Result of FASTA (omim) for
pFN21AB8305
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8305, 657 aa
1>>>pF1KB8305 657 - 657 aa - 657 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4088+/-0.000569; mu= 2.1785+/- 0.035
mean_var=591.6538+/-134.146, 0's: 0 Z-trim(117.5): 1880 B-trim: 0 in 0/54
Lambda= 0.052728
statistics sampled from 26943 (29510) to 26943 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.346), width: 16
Scan time: 10.640
The best scores are: opt bits E(85289)
NP_976226 (OMIM: 602539) mitogen-activated protein ( 657) 4370 348.7 3.9e-95
XP_005257433 (OMIM: 602539) PREDICTED: mitogen-act ( 653) 4327 345.4 3.8e-94
NP_002392 (OMIM: 602539) mitogen-activated protein ( 626) 3899 312.8 2.4e-84
NP_001317360 (OMIM: 602539) mitogen-activated prot ( 622) 3856 309.6 2.3e-83
XP_005257435 (OMIM: 602539) PREDICTED: mitogen-act ( 532) 3466 279.8 1.8e-74
NP_006600 (OMIM: 609487) mitogen-activated protein ( 619) 2597 213.8 1.5e-54
XP_016864974 (OMIM: 600982,613762) PREDICTED: mito (1349) 714 71.1 3e-11
XP_016864973 (OMIM: 600982,613762) PREDICTED: mito (1375) 714 71.1 3e-11
NP_005912 (OMIM: 600982,613762) mitogen-activated (1512) 714 71.2 3.1e-11
NP_001278887 (OMIM: 602425) mitogen-activated prot (1061) 687 68.9 1.1e-10
XP_016866358 (OMIM: 602425) PREDICTED: mitogen-act (1517) 687 69.1 1.3e-10
NP_001288001 (OMIM: 602425) mitogen-activated prot (1604) 687 69.2 1.3e-10
NP_005913 (OMIM: 602425) mitogen-activated protein (1608) 687 69.2 1.3e-10
XP_005267046 (OMIM: 602425) PREDICTED: mitogen-act (1554) 671 67.9 3.1e-10
NP_006715 (OMIM: 602425) mitogen-activated protein (1558) 671 67.9 3.1e-10
XP_011543813 (OMIM: 300820) PREDICTED: mitogen-act ( 748) 593 61.5 1.3e-08
XP_011543812 (OMIM: 300820) PREDICTED: mitogen-act ( 871) 593 61.6 1.4e-08
XP_011543810 (OMIM: 300820) PREDICTED: mitogen-act (1295) 593 61.9 1.7e-08
NP_001001671 (OMIM: 300820) mitogen-activated prot (1313) 593 61.9 1.7e-08
XP_011543809 (OMIM: 300820) PREDICTED: mitogen-act (1324) 593 61.9 1.7e-08
XP_016858260 (OMIM: 604468) PREDICTED: mitogen-act ( 869) 582 60.8 2.5e-08
XP_016866366 (OMIM: 602448) PREDICTED: mitogen-act (1181) 583 61.0 2.8e-08
XP_016866365 (OMIM: 602448) PREDICTED: mitogen-act (1191) 583 61.1 2.8e-08
XP_011534141 (OMIM: 602448) PREDICTED: mitogen-act (1286) 583 61.1 2.9e-08
NP_005914 (OMIM: 602448) mitogen-activated protein (1374) 583 61.2 3e-08
NP_001284538 (OMIM: 604468) mitogen-activated prot (1280) 582 61.0 3e-08
NP_004663 (OMIM: 604468) mitogen-activated protein (1288) 582 61.0 3.1e-08
XP_016866364 (OMIM: 602448) PREDICTED: mitogen-act (1447) 583 61.2 3.1e-08
XP_016866363 (OMIM: 602448) PREDICTED: mitogen-act (1458) 583 61.2 3.1e-08
XP_016866362 (OMIM: 602448) PREDICTED: mitogen-act (1483) 583 61.2 3.1e-08
XP_016866361 (OMIM: 602448) PREDICTED: mitogen-act (1484) 583 61.2 3.1e-08
XP_016866360 (OMIM: 602448) PREDICTED: mitogen-act (1493) 583 61.2 3.1e-08
XP_016866359 (OMIM: 602448) PREDICTED: mitogen-act (1494) 583 61.2 3.1e-08
XP_011534679 (OMIM: 604923) PREDICTED: mitogen-act ( 845) 513 55.5 9.4e-07
NP_942089 (OMIM: 604923) mitogen-activated protein ( 846) 513 55.5 9.4e-07
NP_006566 (OMIM: 604923) mitogen-activated protein ( 846) 513 55.5 9.4e-07
XP_006720076 (OMIM: 604923) PREDICTED: mitogen-act ( 846) 513 55.5 9.4e-07
XP_011544288 (OMIM: 613199) PREDICTED: serine/thre ( 851) 513 55.5 9.4e-07
NP_001257354 (OMIM: 604921) mitogen-activated prot ( 873) 512 55.4 1e-06
NP_003609 (OMIM: 604921) mitogen-activated protein ( 894) 512 55.4 1e-06
NP_004774 (OMIM: 613199) serine/threonine-protein (1049) 513 55.6 1e-06
XP_011544287 (OMIM: 613199) PREDICTED: serine/thre (1055) 513 55.6 1.1e-06
XP_011544286 (OMIM: 613199) PREDICTED: serine/thre (1056) 513 55.6 1.1e-06
NP_001238972 (OMIM: 613199) serine/threonine-prote (1122) 513 55.7 1.1e-06
NP_057235 (OMIM: 613199) serine/threonine-protein (1235) 513 55.8 1.1e-06
XP_011544285 (OMIM: 613199) PREDICTED: serine/thre (1241) 513 55.8 1.1e-06
XP_011544284 (OMIM: 613199) PREDICTED: serine/thre (1242) 513 55.8 1.1e-06
XP_016873585 (OMIM: 603166) PREDICTED: mitogen-act ( 584) 500 54.2 1.6e-06
NP_001036065 (OMIM: 601983) mitogen-activated prot ( 821) 503 54.7 1.6e-06
NP_009112 (OMIM: 601983) mitogen-activated protein ( 833) 503 54.7 1.6e-06
>>NP_976226 (OMIM: 602539) mitogen-activated protein kin (657 aa)
initn: 4370 init1: 4370 opt: 4370 Z-score: 1828.9 bits: 348.7 E(85289): 3.9e-95
Smith-Waterman score: 4370; 100.0% identity (100.0% similar) in 657 aa overlap (1-657:1-657)
10 20 30 40 50 60
pF1KB8 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
550 560 570 580 590 600
610 620 630 640 650
pF1KB8 YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_976 YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
610 620 630 640 650
>>XP_005257433 (OMIM: 602539) PREDICTED: mitogen-activat (653 aa)
initn: 2633 init1: 2633 opt: 4327 Z-score: 1811.2 bits: 345.4 E(85289): 3.8e-94
Smith-Waterman score: 4327; 99.4% identity (99.4% similar) in 657 aa overlap (1-657:1-653)
10 20 30 40 50 60
pF1KB8 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_005 EQCMLDPLSSAENSLSGSCQSL----DSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
250 260 270 280 290
310 320 330 340 350 360
pF1KB8 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB8 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB8 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB8 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB8 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
540 550 560 570 580 590
610 620 630 640 650
pF1KB8 YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
600 610 620 630 640 650
>>NP_002392 (OMIM: 602539) mitogen-activated protein kin (626 aa)
initn: 4167 init1: 3899 opt: 3899 Z-score: 1635.4 bits: 312.8 E(85289): 2.4e-84
Smith-Waterman score: 4109; 95.3% identity (95.3% similar) in 657 aa overlap (1-657:1-626)
10 20 30 40 50 60
pF1KB8 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
::::::::::::::::::::::::::::::::::::::::::
NP_002 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQ------------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
:::::::::::::::::::::::::::::::::::::::::::::::
NP_002 -------------SDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
50 60 70 80
130 140 150 160 170 180
pF1KB8 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB8 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB8 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB8 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB8 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB8 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB8 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB8 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
510 520 530 540 550 560
610 620 630 640 650
pF1KB8 YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
570 580 590 600 610 620
>>NP_001317360 (OMIM: 602539) mitogen-activated protein (622 aa)
initn: 2901 init1: 2633 opt: 3856 Z-score: 1617.8 bits: 309.6 E(85289): 2.3e-83
Smith-Waterman score: 4066; 94.7% identity (94.7% similar) in 657 aa overlap (1-657:1-622)
10 20 30 40 50 60
pF1KB8 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQ------------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------SDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
50 60 70 80
130 140 150 160 170 180
pF1KB8 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB8 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB8 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_001 EQCMLDPLSSAENSLSGSCQSL----DSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB8 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB8 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB8 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB8 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB8 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
510 520 530 540 550 560
610 620 630 640 650
pF1KB8 YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
570 580 590 600 610 620
>>XP_005257435 (OMIM: 602539) PREDICTED: mitogen-activat (532 aa)
initn: 3466 init1: 3466 opt: 3466 Z-score: 1458.0 bits: 279.8 E(85289): 1.8e-74
Smith-Waterman score: 3466; 100.0% identity (100.0% similar) in 524 aa overlap (1-524:1-524)
10 20 30 40 50 60
pF1KB8 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFG
::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGAWAALWWRC
490 500 510 520 530
550 560 570 580 590 600
pF1KB8 ASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE
>>NP_006600 (OMIM: 609487) mitogen-activated protein kin (619 aa)
initn: 2592 init1: 1618 opt: 2597 Z-score: 1100.2 bits: 213.8 E(85289): 1.5e-54
Smith-Waterman score: 2624; 62.7% identity (78.7% similar) in 663 aa overlap (1-654:1-617)
10 20 30 40 50 60
pF1KB8 MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQKKHNSSSSALLNSPTVTT
::.:.::::::.::..:. : . :: : : :. ::.:
NP_006 MDDQQALNSIMQDLAVLHKASRPALSLQETRKAK----SSSPKKQN--------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 SSCAGASEKKKFLSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNE
:::.:::: ::.::. : :::: ::.. :. .::: .:::: :::
NP_006 --------------DVRVKFEHRGEKRILQFPRPVKLEDLRSKAKIAFGQSMDLHYTNNE
50 60 70 80
130 140 150 160 170 180
pF1KB8 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
: : : .:::::::...:::: ::::.:::. .: .. . .. :
NP_006 LVIPLTTQDDLDKAVELLDRSIHMKSLKILLVI-----------NGSTQATNLEPLPSLE
90 100 110 120 130
190 200 210 220 230
pF1KB8 DI-NTIYQPPEPRSRHLSV-SSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPE
:. ::.. :...::. . . ::::::::.:.. ...::.::.::::::::::::
NP_006 DLDNTVFGAE--RKKRLSIIGPTSRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPE
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB8 TSEQCMLDPLS--SAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQL
. .: :::::: : ::: :::: ::: :. :. :::: ::::.:::.::.:: .. .
NP_006 SMDQ-MLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPI
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB8 YDKGVKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLF----TLVPSSRSLSTNGEN
..: :::::::::::: ::..:.:::.:::: :: ::. . .. :...::::.. .
NP_006 FEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSLRSPVSFSPTDHSLSTSSGS
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB8 MGLAVQYLDPRGRLRSADSEN-ALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCY
.. .: : : : :..: .: .:.:.. . :..:: :: ::: ::::::::::::::::
NP_006 SIFTPEYDDSRIRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCY
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB8 DVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLT
::::::::: ::::::::::::::::.:::::::::::: ::::::::::::: ::::.
NP_006 DVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLS
380 390 400 410 420 430
480 490 500 510 520 530
pF1KB8 IFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA
::::::::::.::::::::::::.::::::::::::. :::::::::::::::::::::.
NP_006 IFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDST
440 450 460 470 480 490
540 550 560 570 580 590
pF1KB8 GNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEM
::::::::::::::::::.:::::.::::::::::::::::::::::::.::..::::::
NP_006 GNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEM
500 510 520 530 540 550
600 610 620 630 640 650
pF1KB8 LTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHH
:::::::::.::::::::::::::::.:: :.:.. ::::.::::::. ::::.::: :
NP_006 LTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSADELLRHM
560 570 580 590 600 610
pF1KB8 FAQLMY
:..
NP_006 FVHYH
>>XP_016864974 (OMIM: 600982,613762) PREDICTED: mitogen- (1349 aa)
initn: 634 init1: 219 opt: 714 Z-score: 323.0 bits: 71.1 E(85289): 3e-11
Smith-Waterman score: 714; 30.7% identity (60.7% similar) in 511 aa overlap (160-650:853-1342)
130 140 150 160 170 180
pF1KB8 DLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAGDINTIYQPP
:.::.. . ..... . . . .:
XP_016 PSSSTPSVPAGTATDVSKHRLQGFIPCRIPSASPQTQRKFSLQFHRNCPENKDSDKLSPV
830 840 850 860 870 880
190 200 210 220 230 240
pF1KB8 EPRSRHLSVSS-QNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPL
.:: : :. . : : : :: . ..::. .. . .. ..: .: : .
XP_016 FTQSRPLPSSNIHRPKPSRPTPG-------NTSKQGDPSKNSMTLDL--NSSSKCD-DSF
890 900 910 920 930
250 260 270 280 290 300
pF1KB8 SSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKGVKGGTYPR
. . :: :.. :... .: .: :.. . .. .. . : : :.
XP_016 GCSSNS-SNAVIPSDETVFTPVEEKCRLDVNTELNSSIEDLLEASMPSSDTTV---TF--
940 950 960 970 980
310 320 330 340 350 360
pF1KB8 RYHVSVHHKDYSDGRRTFPR-IRRHQGNLFTLVPSSRSLSTNGENMGLAVQYLDPRGRLR
. .:.: . ... :. . ..: . . . . :. . . : .:.
XP_016 KSEVAVLSPEKAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQ
990 1000 1010 1020 1030 1040
370 380 390 400 410
pF1KB8 SADSENALSVQE---RNVP----TKSP-SAPINWRRGKLLGQGAFGRVYLCYDVDTGREL
..:. . .:. ...: .:.: .: .:. .: :::. : :: :: .
XP_016 VENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLM
1050 1060 1070 1080 1090 1100
420 430 440 450 460 470
pF1KB8 ASKQVQFDPDSPETSKEV-SALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMP
: ::: . .. ..:: ::. ::.....:.: :... : .... .: :.:.:
XP_016 AVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNL--FIEWMA
1110 1120 1130 1140 1150 1160
480 490 500 510 520 530
pF1KB8 GGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGN-VKLG
:::: :. :::. :::. .::.:.:.:.:::: :.:.:::.::::.: ::.:. ....
XP_016 GGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIA
1170 1180 1190 1200 1210 1220
540 550 560 570 580 590
pF1KB8 DFGASKRLQTICMSGTG----MRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLT
::::. :: . .::: . .. :: .:.:::. :. :::. ::::.::...::
XP_016 DFGAAARLAS---KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMAC
1230 1240 1250 1260 1270 1280
600 610 620 630 640
pF1KB8 EKPPW-AEYEA--MAAIFKIATQPTNPQLPSHISEHGRDF-LRRIFVEARQRPSAEELLT
:::: :: .. .: :::::. : :..:::.: :: :: . .. ..:: ..:::
XP_016 AKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK
1290 1300 1310 1320 1330 1340
650
pF1KB8 HHFAQLMY
:
XP_016 HPVFRTTW
>>XP_016864973 (OMIM: 600982,613762) PREDICTED: mitogen- (1375 aa)
initn: 634 init1: 219 opt: 714 Z-score: 323.0 bits: 71.1 E(85289): 3e-11
Smith-Waterman score: 714; 30.7% identity (60.7% similar) in 511 aa overlap (160-650:879-1368)
130 140 150 160 170 180
pF1KB8 DLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAGDINTIYQPP
:.::.. . ..... . . . .:
XP_016 PSSSTPSVPAGTATDVSKHRLQGFIPCRIPSASPQTQRKFSLQFHRNCPENKDSDKLSPV
850 860 870 880 890 900
190 200 210 220 230 240
pF1KB8 EPRSRHLSVSS-QNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPL
.:: : :. . : : : :: . ..::. .. . .. ..: .: : .
XP_016 FTQSRPLPSSNIHRPKPSRPTPG-------NTSKQGDPSKNSMTLDL--NSSSKCD-DSF
910 920 930 940 950
250 260 270 280 290 300
pF1KB8 SSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKGVKGGTYPR
. . :: :.. :... .: .: :.. . .. .. . : : :.
XP_016 GCSSNS-SNAVIPSDETVFTPVEEKCRLDVNTELNSSIEDLLEASMPSSDTTV---TF--
960 970 980 990 1000 1010
310 320 330 340 350 360
pF1KB8 RYHVSVHHKDYSDGRRTFPR-IRRHQGNLFTLVPSSRSLSTNGENMGLAVQYLDPRGRLR
. .:.: . ... :. . ..: . . . . :. . . : .:.
XP_016 KSEVAVLSPEKAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQ
1020 1030 1040 1050 1060 1070
370 380 390 400 410
pF1KB8 SADSENALSVQE---RNVP----TKSP-SAPINWRRGKLLGQGAFGRVYLCYDVDTGREL
..:. . .:. ...: .:.: .: .:. .: :::. : :: :: .
XP_016 VENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLM
1080 1090 1100 1110 1120 1130
420 430 440 450 460 470
pF1KB8 ASKQVQFDPDSPETSKEV-SALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMP
: ::: . .. ..:: ::. ::.....:.: :... : .... .: :.:.:
XP_016 AVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNL--FIEWMA
1140 1150 1160 1170 1180 1190
480 490 500 510 520 530
pF1KB8 GGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGN-VKLG
:::: :. :::. :::. .::.:.:.:.:::: :.:.:::.::::.: ::.:. ....
XP_016 GGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIA
1200 1210 1220 1230 1240 1250
540 550 560 570 580 590
pF1KB8 DFGASKRLQTICMSGTG----MRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLT
::::. :: . .::: . .. :: .:.:::. :. :::. ::::.::...::
XP_016 DFGAAARLAS---KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMAC
1260 1270 1280 1290 1300
600 610 620 630 640
pF1KB8 EKPPW-AEYEA--MAAIFKIATQPTNPQLPSHISEHGRDF-LRRIFVEARQRPSAEELLT
:::: :: .. .: :::::. : :..:::.: :: :: . .. ..:: ..:::
XP_016 AKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK
1310 1320 1330 1340 1350 1360
650
pF1KB8 HHFAQLMY
:
XP_016 HPVFRTTW
1370
>>NP_005912 (OMIM: 600982,613762) mitogen-activated prot (1512 aa)
initn: 634 init1: 219 opt: 714 Z-score: 322.6 bits: 71.2 E(85289): 3.1e-11
Smith-Waterman score: 714; 30.7% identity (60.7% similar) in 511 aa overlap (160-650:1016-1505)
130 140 150 160 170 180
pF1KB8 DLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAGDINTIYQPP
:.::.. . ..... . . . .:
NP_005 PSSSTPSVPAGTATDVSKHRLQGFIPCRIPSASPQTQRKFSLQFHRNCPENKDSDKLSPV
990 1000 1010 1020 1030 1040
190 200 210 220 230 240
pF1KB8 EPRSRHLSVSS-QNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPL
.:: : :. . : : : :: . ..::. .. . .. ..: .: : .
NP_005 FTQSRPLPSSNIHRPKPSRPTPG-------NTSKQGDPSKNSMTLDL--NSSSKCD-DSF
1050 1060 1070 1080 1090
250 260 270 280 290 300
pF1KB8 SSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKGVKGGTYPR
. . :: :.. :... .: .: :.. . .. .. . : : :.
NP_005 GCSSNS-SNAVIPSDETVFTPVEEKCRLDVNTELNSSIEDLLEASMPSSDTTV---TF--
1100 1110 1120 1130 1140
310 320 330 340 350 360
pF1KB8 RYHVSVHHKDYSDGRRTFPR-IRRHQGNLFTLVPSSRSLSTNGENMGLAVQYLDPRGRLR
. .:.: . ... :. . ..: . . . . :. . . : .:.
NP_005 KSEVAVLSPEKAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQ
1150 1160 1170 1180 1190 1200
370 380 390 400 410
pF1KB8 SADSENALSVQE---RNVP----TKSP-SAPINWRRGKLLGQGAFGRVYLCYDVDTGREL
..:. . .:. ...: .:.: .: .:. .: :::. : :: :: .
NP_005 VENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLM
1210 1220 1230 1240 1250 1260
420 430 440 450 460 470
pF1KB8 ASKQVQFDPDSPETSKEV-SALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMP
: ::: . .. ..:: ::. ::.....:.: :... : .... .: :.:.:
NP_005 AVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNL--FIEWMA
1270 1280 1290 1300 1310 1320
480 490 500 510 520 530
pF1KB8 GGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGN-VKLG
:::: :. :::. :::. .::.:.:.:.:::: :.:.:::.::::.: ::.:. ....
NP_005 GGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIA
1330 1340 1350 1360 1370 1380
540 550 560 570 580 590
pF1KB8 DFGASKRLQTICMSGTG----MRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLT
::::. :: . .::: . .. :: .:.:::. :. :::. ::::.::...::
NP_005 DFGAAARLAS---KGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMAC
1390 1400 1410 1420 1430 1440
600 610 620 630 640
pF1KB8 EKPPW-AEYEA--MAAIFKIATQPTNPQLPSHISEHGRDF-LRRIFVEARQRPSAEELLT
:::: :: .. .: :::::. : :..:::.: :: :: . .. ..:: ..:::
NP_005 AKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK
1450 1460 1470 1480 1490 1500
650
pF1KB8 HHFAQLMY
:
NP_005 HPVFRTTW
1510
>>NP_001278887 (OMIM: 602425) mitogen-activated protein (1061 aa)
initn: 525 init1: 216 opt: 687 Z-score: 312.9 bits: 68.9 E(85289): 1.1e-10
Smith-Waterman score: 703; 30.3% identity (59.2% similar) in 512 aa overlap (151-655:574-1056)
130 140 150 160 170 180
pF1KB8 LSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAG
:... .: ..::: :. .:
NP_001 WATQGFDFLQAIEPAFISALPEDDFLSLQALMNECIGHVIGKPHSPVTGLYLAIHRNSPR
550 560 570 580 590 600
190 200 210 220 230 240
pF1KB8 DINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETS
... .: . :: . . . . :. . . . : .. .. . .. : .
NP_001 PMKVPRCHSDPPNPHLIIPTPEGFSTRSMPSDARSHGSPAAAAAAAAAAVAASRPSPSGG
610 620 630 640 650 660
250 260 270 280 290
pF1KB8 EQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSR-MSRAQSFPDNRQEYSDRETQLYDK
.. . .:::... ..: :: :. . . : .:: .: ..:.: . : .
NP_001 DSVLPKSISSAHDTRGSSVPENDRLASIAAELQFRSLSRHSSPTEERDEPA------YPR
670 680 690 700 710
300 310 320 330 340 350
pF1KB8 GVKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQY
: ..:. : ... . .. .: . :. : .. : .: .: . :
NP_001 GDSSGSTRRSWELRTLISQSKDTASKLGPIEAIQKSV-RLFEEKRYREMRRKN--IIGQV
720 730 740 750 760 770
360 370 380 390 400 410
pF1KB8 LD-PRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRE
: : .: : :.. : :.: : :.::. .:.: .:.:: : .::::.
NP_001 CDTP----KSYD--NVMHVGLRKVTFK-------WQRGNKIGEGQYGKVYTCISVDTGEL
780 790 800 810 820
420 430 440 450 460 470
pF1KB8 LASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMP
.: :...:.:.. .: ::.. :........: .:.:.: : : . :::::
NP_001 MAMKEIRFQPNDHKTIKETAD---ELKIFEGIKHPNLVRYFGVELHREE--MYIFMEYCD
830 840 850 860 870
480 490 500 510 520 530
pF1KB8 GGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGD
:.. .... : : : : : :..:: ... :: . :::::::::::. :.: .::::
NP_001 EGTL-EEVSRLG-LQEHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGD
880 890 900 910 920 930
540 550 560 570 580 590
pF1KB8 FGASKRLQTICMSGTG-MRSVTGTPYWMSPEVIS---GEGYGRKADVWSLGCTVVEMLTE
:: : .:.. .. : . :. :: .:.::::. :::.:: ::.:::::.:.::.:
NP_001 FGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTG
940 950 960 970 980 990
600 610 620 630 640 650
pF1KB8 KPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIF-VEARQRPSAEELLTHHFA
: :: ::: :. . . .: .: ..: .:.::: . . . ..: .: .:: : :.
NP_001 KRPWHEYEHNFQIMYKVGMGHKPPIPERLSPEGKDFLSHCLESDPKMRWTASQLLDHSFV
1000 1010 1020 1030 1040 1050
pF1KB8 QLMY
..
NP_001 KVCTDEE
1060
657 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:35:00 2016 done: Fri Nov 4 11:35:02 2016
Total Scan time: 10.640 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]