Result of FASTA (omim) for
pFN21AB8110
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8110, 180 aa
1>>>pF1KB8110 180 - 180 aa - 180 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2865+/-0.000268; mu= 6.3226+/- 0.017
mean_var=165.9977+/-34.257, 0's: 0 Z-trim(125.0): 19 B-trim: 756 in 1/55
Lambda= 0.099546
statistics sampled from 47742 (47762) to 47742 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.856), E-opt: 0.2 (0.56), width: 16
Scan time: 5.570
The best scores are: opt bits E(85289)
NP_001191013 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_001265093 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_001191014 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_001265094 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_005371 (OMIM: 600613) neuroblastoma suppressor ( 181) 1312 198.7 4.2e-51
NP_001265095 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_001191015 (OMIM: 600613) neuroblastoma suppress ( 215) 1312 198.8 4.7e-51
NP_877421 (OMIM: 600613) neuroblastoma suppressor ( 216) 1312 198.8 4.7e-51
XP_011542551 (OMIM: 608832) PREDICTED: gremlin-2 i ( 168) 249 46.0 3.6e-05
NP_071914 (OMIM: 608832) gremlin-2 precursor [Homo ( 168) 249 46.0 3.6e-05
XP_005273283 (OMIM: 608832) PREDICTED: gremlin-2 i ( 186) 249 46.1 3.8e-05
NP_001178252 (OMIM: 603054) gremlin-1 isoform 2 pr ( 143) 231 43.4 0.00019
NP_001178251 (OMIM: 603054) gremlin-1 isoform 3 [H ( 114) 219 41.6 0.00053
NP_037504 (OMIM: 603054) gremlin-1 isoform 1 precu ( 184) 219 41.8 0.00075
XP_016877566 (OMIM: 603054) PREDICTED: gremlin-1 i ( 221) 219 41.8 0.00086
XP_005254358 (OMIM: 603054) PREDICTED: gremlin-1 i ( 240) 219 41.9 0.00091
>>NP_001191013 (OMIM: 600613) neuroblastoma suppressor o (181 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1038.5 bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)
10 20 30 40 50
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
130 140 150 160 170 180
180
pF1KB8 D
:
NP_001 D
>>NP_001265093 (OMIM: 600613) neuroblastoma suppressor o (181 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1038.5 bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)
10 20 30 40 50
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
130 140 150 160 170 180
180
pF1KB8 D
:
NP_001 D
>>NP_001191014 (OMIM: 600613) neuroblastoma suppressor o (181 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1038.5 bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)
10 20 30 40 50
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
130 140 150 160 170 180
180
pF1KB8 D
:
NP_001 D
>>NP_001265094 (OMIM: 600613) neuroblastoma suppressor o (181 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1038.5 bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)
10 20 30 40 50
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
130 140 150 160 170 180
180
pF1KB8 D
:
NP_001 D
>>NP_005371 (OMIM: 600613) neuroblastoma suppressor of t (181 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1038.5 bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)
10 20 30 40 50
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
130 140 150 160 170 180
180
pF1KB8 D
:
NP_005 D
>>NP_001265095 (OMIM: 600613) neuroblastoma suppressor o (181 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1038.5 bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)
10 20 30 40 50
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
130 140 150 160 170 180
180
pF1KB8 D
:
NP_001 D
>>NP_001191015 (OMIM: 600613) neuroblastoma suppressor o (215 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1037.6 bits: 198.8 E(85289): 4.7e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:36-215)
10 20 30
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDK
::::::::::::::::::::::::::::::
NP_001 LQQLISMDLFWRLFFVCGQEGLRALEATGMMLRVLVGAVLPAMLLAAPPPINKLALFPDK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 SAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSM
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 WEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPH
130 140 150 160 170 180
160 170 180
pF1KB8 PHPHPHPGGQTPEPEDPPGAPHTEEEGAED
::::::::::::::::::::::::::::::
NP_001 PHPHPHPGGQTPEPEDPPGAPHTEEEGAED
190 200 210
>>NP_877421 (OMIM: 600613) neuroblastoma suppressor of t (216 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1037.5 bits: 198.8 E(85289): 4.7e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:37-216)
10 20 30
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDK
::::::::::::::::::::::::::::::
NP_877 SQTSRAVSIWKFPAKLGKTHGHRALEATGMMLRVLVGAVLPAMLLAAPPPINKLALFPDK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 SAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSM
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 WEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 WEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPH
130 140 150 160 170 180
160 170 180
pF1KB8 PHPHPHPGGQTPEPEDPPGAPHTEEEGAED
::::::::::::::::::::::::::::::
NP_877 PHPHPHPGGQTPEPEDPPGAPHTEEEGAED
190 200 210
>>XP_011542551 (OMIM: 608832) PREDICTED: gremlin-2 isofo (168 aa)
initn: 231 init1: 217 opt: 249 Z-score: 213.9 bits: 46.0 E(85289): 3.6e-05
Smith-Waterman score: 249; 35.9% identity (62.0% similar) in 92 aa overlap (30-121:69-159)
10 20 30 40 50
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
:: ::... . : :.. ::....: :: :
XP_011 SNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCY
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
::: :. .: . ::. : : : . .: ::::: . :. : ..:. .: :
XP_011 GQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKK-IQKVKQCRC
100 110 120 130 140 150
120 130 140 150 160 170
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
..
XP_011 MSVNLSDSDKQ
160
>>NP_071914 (OMIM: 608832) gremlin-2 precursor [Homo sap (168 aa)
initn: 231 init1: 217 opt: 249 Z-score: 213.9 bits: 46.0 E(85289): 3.6e-05
Smith-Waterman score: 249; 35.9% identity (62.0% similar) in 92 aa overlap (30-121:69-159)
10 20 30 40 50
pF1KB8 MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
:: ::... . : :.. ::....: :: :
NP_071 SNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCY
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
::: :. .: . ::. : : : . .: ::::: . :. : ..:. .: :
NP_071 GQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKK-IQKVKQCRC
100 110 120 130 140 150
120 130 140 150 160 170
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
..
NP_071 MSVNLSDSDKQ
160
180 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:36:01 2016 done: Fri Nov 4 09:36:02 2016
Total Scan time: 5.570 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]