Result of FASTA (omim) for
pFN21AB7611
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7611, 302 aa
1>>>pF1KB7611 302 - 302 aa - 302 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8862+/-0.000349; mu= 2.3701+/- 0.022
mean_var=309.5729+/-62.841, 0's: 0 Z-trim(124.4): 222 B-trim: 134 in 2/57
Lambda= 0.072894
statistics sampled from 45777 (46061) to 45777 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.834), E-opt: 0.2 (0.54), width: 16
Scan time: 6.540
The best scores are: opt bits E(85289)
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302) 2058 229.0 8.8e-60
XP_011530329 (OMIM: 137600,180500,180550,601542,60 ( 271) 1011 118.9 1.1e-26
NP_001191328 (OMIM: 137600,180500,180550,601542,60 ( 271) 1011 118.9 1.1e-26
NP_700476 (OMIM: 137600,180500,180550,601542,60422 ( 271) 1011 118.9 1.1e-26
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317) 1010 118.9 1.4e-26
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317) 1010 118.9 1.4e-26
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317) 1010 118.9 1.4e-26
NP_000316 (OMIM: 137600,180500,180550,601542,60422 ( 324) 1008 118.7 1.6e-26
NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314) 801 96.9 5.6e-20
NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 442 59.4 1.9e-08
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 366 51.2 3.5e-06
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 363 50.8 3.8e-06
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 363 50.9 4.4e-06
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 364 51.0 4.5e-06
XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 342 48.4 1.6e-05
NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326) 342 48.6 1.9e-05
NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354) 340 48.4 2.4e-05
NP_001186699 (OMIM: 600036) homeobox protein OTX1 ( 354) 340 48.4 2.4e-05
NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 336 47.8 2.4e-05
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 342 48.8 2.6e-05
NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 342 48.9 2.6e-05
NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 342 48.9 2.6e-05
NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377) 338 48.3 2.9e-05
XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377) 338 48.3 2.9e-05
XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377) 338 48.3 2.9e-05
NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382) 338 48.3 2.9e-05
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 335 48.0 3.7e-05
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 332 47.7 4.6e-05
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 328 47.0 4.7e-05
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 329 47.2 5e-05
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 332 47.8 5.2e-05
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 332 47.8 5.2e-05
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 332 47.8 5.2e-05
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 332 47.8 5.4e-05
NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 322 46.4 7.1e-05
NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406) 325 46.9 7.7e-05
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 317 45.7 8.6e-05
NP_001257454 (OMIM: 600037,610125,613986) homeobox ( 297) 318 46.0 0.00011
NP_068374 (OMIM: 600037,610125,613986) homeobox pr ( 297) 318 46.0 0.00011
NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289) 310 45.2 0.00019
NP_758840 (OMIM: 600037,610125,613986) homeobox pr ( 289) 310 45.2 0.00019
NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289) 310 45.2 0.00019
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 312 45.6 0.0002
NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184) 303 44.2 0.00023
NP_001290437 (OMIM: 612019) intestine-specific hom ( 245) 304 44.5 0.00026
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 305 44.7 0.00028
NP_005306 (OMIM: 601845) homeobox protein goosecoi ( 205) 284 42.3 0.00099
NP_001297090 (OMIM: 106210,120430,136520,148190,16 ( 286) 286 42.7 0.0011
NP_001297089 (OMIM: 106210,120430,136520,148190,16 ( 286) 286 42.7 0.0011
NP_000545 (OMIM: 120970,268000,602225,613829) cone ( 299) 284 42.5 0.0013
>>NP_005020 (OMIM: 107250,602669,610623) pituitary homeo (302 aa)
initn: 2058 init1: 2058 opt: 2058 Z-score: 1194.3 bits: 229.0 E(85289): 8.8e-60
Smith-Waterman score: 2058; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302)
10 20 30 40 50 60
pF1KB7 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 KQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVER
250 260 270 280 290 300
pF1KB7 PV
::
NP_005 PV
>>XP_011530329 (OMIM: 137600,180500,180550,601542,604229 (271 aa)
initn: 1012 init1: 712 opt: 1011 Z-score: 599.8 bits: 118.9 E(85289): 1.1e-26
Smith-Waterman score: 1011; 61.0% identity (79.8% similar) in 277 aa overlap (33-302:12-271)
10 20 30 40 50 60
pF1KB7 FGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQ
: :.. :.... :. :: : ::.:
XP_011 METNCRKLVSACVQLEKDKSQQGKNEDVGA--EDPSKKKRQ
10 20 30
70 80 90 100 110 120
pF1KB7 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 SQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPFAFNSVNVGP
.:::::::..:. ..::. ::...::::::.:: :.: . :..:.::: :::.::.:
XP_011 NQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF-FNSMNVNP
100 110 120 130 140 150
190 200 210 220 230
pF1KB7 LASQPVFSPPSSIAASMVPSAAAAPGTVPG-PGA-LQGLGG----GPPGLAPAAVSSGAV
:.:: .::::.::. :: :.. .:..: : ::. :..:.. . :.: .:: . :
XP_011 LSSQSMFSPPNSIS-SMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN-SAVPTPA-
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 SCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQ
:::: . :::::: :::::::::::::::.::.: .:..: :.::: ::
XP_011 -CPYAPP--------TPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNP--ASNLSACQ
220 230 240 250 260
300
pF1KB7 YAVERPV
:::.:::
XP_011 YAVDRPV
270
>>NP_001191328 (OMIM: 137600,180500,180550,601542,604229 (271 aa)
initn: 1012 init1: 712 opt: 1011 Z-score: 599.8 bits: 118.9 E(85289): 1.1e-26
Smith-Waterman score: 1011; 61.0% identity (79.8% similar) in 277 aa overlap (33-302:12-271)
10 20 30 40 50 60
pF1KB7 FGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQ
: :.. :.... :. :: : ::.:
NP_001 METNCRKLVSACVQLEKDKSQQGKNEDVGA--EDPSKKKRQ
10 20 30
70 80 90 100 110 120
pF1KB7 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 SQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPFAFNSVNVGP
.:::::::..:. ..::. ::...::::::.:: :.: . :..:.::: :::.::.:
NP_001 NQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF-FNSMNVNP
100 110 120 130 140 150
190 200 210 220 230
pF1KB7 LASQPVFSPPSSIAASMVPSAAAAPGTVPG-PGA-LQGLGG----GPPGLAPAAVSSGAV
:.:: .::::.::. :: :.. .:..: : ::. :..:.. . :.: .:: . :
NP_001 LSSQSMFSPPNSIS-SMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN-SAVPTPA-
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 SCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQ
:::: . :::::: :::::::::::::::.::.: .:..: :.::: ::
NP_001 -CPYAPP--------TPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNP--ASNLSACQ
220 230 240 250 260
300
pF1KB7 YAVERPV
:::.:::
NP_001 YAVDRPV
270
>>NP_700476 (OMIM: 137600,180500,180550,601542,604229) p (271 aa)
initn: 1012 init1: 712 opt: 1011 Z-score: 599.8 bits: 118.9 E(85289): 1.1e-26
Smith-Waterman score: 1011; 61.0% identity (79.8% similar) in 277 aa overlap (33-302:12-271)
10 20 30 40 50 60
pF1KB7 FGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQ
: :.. :.... :. :: : ::.:
NP_700 METNCRKLVSACVQLEKDKSQQGKNEDVGA--EDPSKKKRQ
10 20 30
70 80 90 100 110 120
pF1KB7 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_700 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 SQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPFAFNSVNVGP
.:::::::..:. ..::. ::...::::::.:: :.: . :..:.::: :::.::.:
NP_700 NQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF-FNSMNVNP
100 110 120 130 140 150
190 200 210 220 230
pF1KB7 LASQPVFSPPSSIAASMVPSAAAAPGTVPG-PGA-LQGLGG----GPPGLAPAAVSSGAV
:.:: .::::.::. :: :.. .:..: : ::. :..:.. . :.: .:: . :
NP_700 LSSQSMFSPPNSIS-SMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN-SAVPTPA-
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 SCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQ
:::: . :::::: :::::::::::::::.::.: .:..: :.::: ::
NP_700 -CPYAPP--------TPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNP--ASNLSACQ
220 230 240 250 260
300
pF1KB7 YAVERPV
:::.:::
NP_700 YAVDRPV
270
>>NP_001191327 (OMIM: 137600,180500,180550,601542,604229 (317 aa)
initn: 1012 init1: 712 opt: 1010 Z-score: 598.4 bits: 118.9 E(85289): 1.4e-26
Smith-Waterman score: 1010; 61.1% identity (80.4% similar) in 275 aa overlap (35-302:59-317)
10 20 30 40 50 60
pF1KB7 LLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRR
: ...:. . . . :. :: : ::.:::
NP_001 DSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQGKNEDVGA-EDPSKKKRQRR
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB7 QRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 QRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQ
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB7 QAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPFAFNSVNVGPLA
::::::..:. ..::. ::...::::::.:: :.: . :..:.::: :::.::.::.
NP_001 QAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF-FNSMNVNPLS
150 160 170 180 190 200
190 200 210 220 230
pF1KB7 SQPVFSPPSSIAASMVPSAAAAPGTVPG-PGA-LQGLGG----GPPGLAPAAVSSGAVSC
:: .::::.::. :: :.. .:..: : ::. :..:.. . :.: .:: . : :
NP_001 SQSMFSPPNSIS-SMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN-SAVPTPA--C
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB7 PYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYA
::: . :::::: :::::::::::::::.::.: .:..: :.::: ::::
NP_001 PYAPP--------TPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNP--ASNLSACQYA
270 280 290 300 310
300
pF1KB7 VERPV
:.:::
NP_001 VDRPV
>>NP_001191326 (OMIM: 137600,180500,180550,601542,604229 (317 aa)
initn: 1012 init1: 712 opt: 1010 Z-score: 598.4 bits: 118.9 E(85289): 1.4e-26
Smith-Waterman score: 1010; 61.1% identity (80.4% similar) in 275 aa overlap (35-302:59-317)
10 20 30 40 50 60
pF1KB7 LLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRR
: ...:. . . . :. :: : ::.:::
NP_001 DSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQGKNEDVGA-EDPSKKKRQRR
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB7 QRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 QRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQ
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB7 QAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPFAFNSVNVGPLA
::::::..:. ..::. ::...::::::.:: :.: . :..:.::: :::.::.::.
NP_001 QAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF-FNSMNVNPLS
150 160 170 180 190 200
190 200 210 220 230
pF1KB7 SQPVFSPPSSIAASMVPSAAAAPGTVPG-PGA-LQGLGG----GPPGLAPAAVSSGAVSC
:: .::::.::. :: :.. .:..: : ::. :..:.. . :.: .:: . : :
NP_001 SQSMFSPPNSIS-SMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN-SAVPTPA--C
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB7 PYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYA
::: . :::::: :::::::::::::::.::.: .:..: :.::: ::::
NP_001 PYAPP--------TPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNP--ASNLSACQYA
270 280 290 300 310
300
pF1KB7 VERPV
:.:::
NP_001 VDRPV
>>NP_700475 (OMIM: 137600,180500,180550,601542,604229) p (317 aa)
initn: 1012 init1: 712 opt: 1010 Z-score: 598.4 bits: 118.9 E(85289): 1.4e-26
Smith-Waterman score: 1010; 61.1% identity (80.4% similar) in 275 aa overlap (35-302:59-317)
10 20 30 40 50 60
pF1KB7 LLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRR
: ...:. . . . :. :: : ::.:::
NP_700 DSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQGKNEDVGA-EDPSKKKRQRR
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB7 QRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_700 QRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQ
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB7 QAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPFAFNSVNVGPLA
::::::..:. ..::. ::...::::::.:: :.: . :..:.::: :::.::.::.
NP_700 QAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF-FNSMNVNPLS
150 160 170 180 190 200
190 200 210 220 230
pF1KB7 SQPVFSPPSSIAASMVPSAAAAPGTVPG-PGA-LQGLGG----GPPGLAPAAVSSGAVSC
:: .::::.::. :: :.. .:..: : ::. :..:.. . :.: .:: . : :
NP_700 SQSMFSPPNSIS-SMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN-SAVPTPA--C
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB7 PYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYA
::: . :::::: :::::::::::::::.::.: .:..: :.::: ::::
NP_700 PYAPP--------TPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNP--ASNLSACQYA
270 280 290 300 310
300
pF1KB7 VERPV
:.:::
NP_700 VDRPV
>>NP_000316 (OMIM: 137600,180500,180550,601542,604229) p (324 aa)
initn: 932 init1: 712 opt: 1008 Z-score: 597.2 bits: 118.7 E(85289): 1.6e-26
Smith-Waterman score: 1013; 56.9% identity (77.6% similar) in 304 aa overlap (6-302:47-324)
10 20 30
pF1KB7 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKG
:. .. : . ..::...:. ... .:
NP_000 TKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 QEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI
. .: ..: :: : ::.::::::::::::::::::::::::::::::::::
NP_000 K----NEDVGA-------EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI
80 90 100 110 120
100 110 120 130 140 150
pF1KB7 AVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGN
:::::::::::::::::::::::::::.:::::::..:. ..::. ::...::::::.:
NP_000 AVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNN
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB7 WPPKAL-APPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG-PG
: :.: . :..:.::: :::.::.::.:: .::::.::. :: :.. .:..: : ::
NP_000 WAAKGLTSASLSTKSFPF-FNSMNVNPLSSQSMFSPPNSIS-SMSMSSSMVPSAVTGVPG
190 200 210 220 230 240
220 230 240 250 260
pF1KB7 A-LQGLGG----GPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLR
. :..:.. . :.: .:: . : :::: . :::::: :::::::::
NP_000 SSLNSLNNLNNLSSPSLN-SAVPTPA--CPYAPP--------TPPYVYRDTCNSSLASLR
250 260 270 280 290
270 280 290 300
pF1KB7 LKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV
::::::.::.: .:..: :.::: :::::.:::
NP_000 LKAKQHSSFGYASVQNP--ASNLSACQYAVDRPV
300 310 320
>>NP_002644 (OMIM: 119800,186550,602149) pituitary homeo (314 aa)
initn: 841 init1: 558 opt: 801 Z-score: 479.7 bits: 96.9 E(85289): 5.6e-20
Smith-Waterman score: 969; 56.3% identity (75.3% similar) in 300 aa overlap (3-296:31-312)
10 20 30
pF1KB7 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHG
: : :. : : : : . . .:::.
NP_002 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREP-LENSASESSDTELPEKE
10 20 30 40 50
40 50 60 70 80 90
pF1KB7 CKGQEHSDSEKASASLPG-GSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMST
.: : . : ..:. : :. .: . ::::::::::::::::::::::::::::::::
NP_002 -RGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSM
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB7 REEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYP-G
:::::::::::: ::::::::::::::::::.:: .::::... ..::: :::.:: :
NP_002 REEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAG
120 130 140 150 160 170
160 170 180 190 200
pF1KB7 YSYGNWPPKALAP-PLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTV
:::.:: :.::: ::..:.: : :::.. ::.:: .:: ::::.. .::. . ::.:
NP_002 YSYNNWAAKSLAPAPLSTKSFTF-FNSMS--PLSSQSMFSAPSSISSMTMPSSMG-PGAV
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 PG-PGA-LQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPY-VYRDPCNSSLAS
:: :.. :..... . .:.: :: :::.. : ::: :::: :::::::
NP_002 PGMPNSGLNNINNLTGSSLNSAMSPGA--CPYGTPA--------SPYSVYRDTCNSSLAS
240 250 260 270 280
270 280 290 300
pF1KB7 LRLKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV
::::.:::.::.: ...: ::..:. :::
NP_002 LRLKSKQHSSFGYGGLQG--PASGLNACQYNS
290 300 310
>>NP_620689 (OMIM: 300004,300215,300382,300419,308350,30 (562 aa)
initn: 385 init1: 329 opt: 442 Z-score: 272.7 bits: 59.4 E(85289): 1.9e-08
Smith-Waterman score: 445; 36.2% identity (61.0% similar) in 287 aa overlap (9-276:273-544)
10 20 30
pF1KB7 MEFGLLSEAEARSPALSLSDAG---TPHPQLPEHGCKG
: : . : ... : .:. .: : .
NP_620 LLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHP-ED
250 260 270 280 290 300
40 50 60 70 80 90
pF1KB7 QEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI
: .:.: . :.. :.: ::.:::: :: ::: ::.::: .::...:::. ::::.
NP_620 AEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREEL
310 320 330 340 350 360
100 110 120 130 140 150
pF1KB7 AVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKG-SFAAPLGGLVP--PYEEVYPGYS
:. .::::::.:::.::::::::::.. : : .::.. : :: .. :
NP_620 AMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASP---
370 380 390 400 410
160 170 180 190 200 210
pF1KB7 YGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAP-GTVPG
.::. : : . :.... .. :. : . :: . .::. ::.: .: :
NP_620 ---FPPHH--PALDS-----AWTAAAAAAAAAFPSLPPPPG-SASLPPSGAPLGLSTFLG
420 430 440 450 460
220 230 240 250
pF1KB7 PGALQGLGGGPPG-------LAPAAVSSGAVS-----CPYASAAAAAAAAASSPYVYRDP
.... . :. .:: . .: :.. : . .:.:..: :. . :
NP_620 AAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADR
470 480 490 500 510 520
260 270 280 290 300
pF1KB7 CNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV
::.:.::::::.::.
NP_620 RASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC
530 540 550 560
302 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:57:23 2016 done: Fri Nov 4 08:57:24 2016
Total Scan time: 6.540 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]