Result of FASTA (omim) for
pFN21AB7559
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7559, 206 aa
1>>>pF1KB7559 206 - 206 aa - 206 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1379+/-0.00029; mu= 7.2367+/- 0.018
mean_var=154.1473+/-30.906, 0's: 0 Z-trim(123.1): 61 B-trim: 2242 in 1/53
Lambda= 0.103301
statistics sampled from 42377 (42443) to 42377 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.498), width: 16
Scan time: 6.660
The best scores are: opt bits E(85289)
NP_005089 (OMIM: 603628) musculin [Homo sapiens] ( 206) 1380 216.1 3.1e-56
NP_938206 (OMIM: 603306) transcription factor 21 [ ( 179) 635 105.0 7.5e-23
NP_003197 (OMIM: 603306) transcription factor 21 [ ( 179) 635 105.0 7.5e-23
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202) 271 50.8 1.8e-06
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202) 271 50.8 1.8e-06
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199) 251 47.9 1.4e-05
NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201) 242 46.5 3.5e-05
XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201) 242 46.5 3.5e-05
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160) 226 44.1 0.00015
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160) 226 44.1 0.00015
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217) 218 43.0 0.00044
NP_005590 (OMIM: 162361) helix-loop-helix protein ( 135) 209 41.5 0.00079
NP_001104531 (OMIM: 162361) helix-loop-helix prote ( 135) 209 41.5 0.00079
XP_005264216 (OMIM: 609635) PREDICTED: transcripti ( 210) 211 41.9 0.00089
NP_786951 (OMIM: 609635) transcription factor 23 [ ( 214) 211 41.9 0.0009
NP_005589 (OMIM: 162360) helix-loop-helix protein ( 133) 198 39.8 0.0024
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328) 200 40.4 0.0038
NP_660161 (OMIM: 609875) protein atonal homolog 7 ( 152) 189 38.5 0.0068
XP_016871769 (OMIM: 604882,610370) PREDICTED: neur ( 214) 191 38.9 0.0071
NP_066279 (OMIM: 604882,610370) neurogenin-3 [Homo ( 214) 191 38.9 0.0071
NP_689627 (OMIM: 613483) class E basic helix-loop- ( 381) 195 39.8 0.0072
NP_005163 (OMIM: 601461) protein atonal homolog 1 ( 354) 194 39.6 0.0075
>>NP_005089 (OMIM: 603628) musculin [Homo sapiens] (206 aa)
initn: 1380 init1: 1380 opt: 1380 Z-score: 1130.5 bits: 216.1 E(85289): 3.1e-56
Smith-Waterman score: 1380; 100.0% identity (100.0% similar) in 206 aa overlap (1-206:1-206)
10 20 30 40 50 60
pF1KB7 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW
130 140 150 160 170 180
190 200
pF1KB7 PFVVSGRPDSDTKEVSAANRLCGTTA
::::::::::::::::::::::::::
NP_005 PFVVSGRPDSDTKEVSAANRLCGTTA
190 200
>>NP_938206 (OMIM: 603306) transcription factor 21 [Homo (179 aa)
initn: 654 init1: 614 opt: 635 Z-score: 531.2 bits: 105.0 E(85289): 7.5e-23
Smith-Waterman score: 635; 71.5% identity (83.2% similar) in 137 aa overlap (70-206:44-178)
40 50 60 70 80 90
pF1KB7 SPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKG
:. :. : :: : . :: : .:
NP_938 EVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQ-KGRGGLGKRRKAPTKKS-PLSG
20 30 40 50 60 70
100 110 120 130 140 150
pF1KB7 SAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHL
. : :: :::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_938 VSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHL
80 90 100 110 120 130
160 170 180 190 200
pF1KB7 RQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
::.: .:.:::::.:::::::::.:.:.:.:: ::: .:.:::::::
NP_938 RQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
140 150 160 170
>>NP_003197 (OMIM: 603306) transcription factor 21 [Homo (179 aa)
initn: 654 init1: 614 opt: 635 Z-score: 531.2 bits: 105.0 E(85289): 7.5e-23
Smith-Waterman score: 635; 71.5% identity (83.2% similar) in 137 aa overlap (70-206:44-178)
40 50 60 70 80 90
pF1KB7 SPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKG
:. :. : :: : . :: : .:
NP_003 EVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQ-KGRGGLGKRRKAPTKKS-PLSG
20 30 40 50 60 70
100 110 120 130 140 150
pF1KB7 SAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHL
. : :: :::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_003 VSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHL
80 90 100 110 120 130
160 170 180 190 200
pF1KB7 RQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
::.: .:.:::::.:::::::::.:.:.:.:: ::: .:.:::::::
NP_003 RQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
140 150 160 170
>>XP_011513798 (OMIM: 101400,123100,180750,601622) PREDI (202 aa)
initn: 416 init1: 170 opt: 271 Z-score: 237.4 bits: 50.8 E(85289): 1.8e-06
Smith-Waterman score: 271; 34.7% identity (58.5% similar) in 193 aa overlap (1-184:5-189)
10 20 30 40 50
pF1KB7 MSTGSVSDPEEMELRGLQREYPVPASKRPPL--RGVERSYASPSDNSSAEEEDPDG
.:.. :: : . : . ..: : ..:: :: .. .: :.. : :
XP_011 MMQDVSSSPVS-PADDSLSNSEEE---PDRQQPPSGKRGGRKRRSS--RRSAGGGAGPGG
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 EEERCALG--TAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAA
. : :: :: . . :: ::.::..::::.. .. .. : :.:: :
XP_011 AAGGGVGGGDEPGSPAQGKRGK-KSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 NARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN--
:.::: : . :..::. :. .: .: : ::::..::.::. :: : :.:: :. ..
XP_011 NVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKM
120 130 140 150 160 170
180 190 200
pF1KB7 ---GYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
.:: :.. : :
XP_011 ASCSYVAHERLSYAFSVWRMEGAWSMSASH
180 190 200
>>NP_000465 (OMIM: 101400,123100,180750,601622) twist-re (202 aa)
initn: 416 init1: 170 opt: 271 Z-score: 237.4 bits: 50.8 E(85289): 1.8e-06
Smith-Waterman score: 271; 34.7% identity (58.5% similar) in 193 aa overlap (1-184:5-189)
10 20 30 40 50
pF1KB7 MSTGSVSDPEEMELRGLQREYPVPASKRPPL--RGVERSYASPSDNSSAEEEDPDG
.:.. :: : . : . ..: : ..:: :: .. .: :.. : :
NP_000 MMQDVSSSPVS-PADDSLSNSEEE---PDRQQPPSGKRGGRKRRSS--RRSAGGGAGPGG
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 EEERCALG--TAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAA
. : :: :: . . :: ::.::..::::.. .. .. : :.:: :
NP_000 AAGGGVGGGDEPGSPAQGKRGK-KSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 NARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN--
:.::: : . :..::. :. .: .: : ::::..::.::. :: : :.:: :. ..
NP_000 NVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKM
120 130 140 150 160 170
180 190 200
pF1KB7 ---GYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
.:: :.. : :
NP_000 ASCSYVAHERLSYAFSVWRMEGAWSMSASH
180 190 200
>>NP_004600 (OMIM: 601010) transcription factor 15 [Homo (199 aa)
initn: 264 init1: 221 opt: 251 Z-score: 221.3 bits: 47.9 E(85289): 1.4e-05
Smith-Waterman score: 251; 42.6% identity (62.3% similar) in 122 aa overlap (53-171:23-137)
30 40 50 60 70 80
pF1KB7 VPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKR--KRPRVAGG
. ::.: .. .. :: . . : . :
NP_004 MAFALLRPVGAHVLYPDVRLLSEDEENRSESDASDQSFGCCEGPEAARRGPG
10 20 30 40 50
90 100 110 120 130 140
pF1KB7 GGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPD
:.: ::::: :.. ::.::::::: : . .. ::. :.: .: : :
NP_004 PGGGRRAGGGG-------GAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVD
60 70 80 90 100
150 160 170 180 190
pF1KB7 TKLSKLDTLRLASSYIAHLRQ-LLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAAN
::::..:::::::::::: . :: : ..:
NP_004 RKLSKIETLRLASSYIAHLANVLLLGDSADDGQPCFRAAGSAKGAVPAAADGGRQPRSIC
110 120 130 140 150 160
200
pF1KB7 RLCGTTA
NP_004 TFCLSNQRKGGGRRDLGGSCLKVRGVAPLRGPRR
170 180 190
>>NP_001073983 (OMIM: 609067) basic helix-loop-helix tra (201 aa)
initn: 279 init1: 197 opt: 242 Z-score: 214.0 bits: 46.5 E(85289): 3.5e-05
Smith-Waterman score: 252; 37.5% identity (57.6% similar) in 144 aa overlap (22-163:8-131)
10 20 30 40 50
pF1KB7 MSTGSVSDPEEMELRGLQREYPVPASKR--PPLRGVERSYASPSDNSSAEEEDPDGEEER
:.: .. : . . .. ::.:...:. . :
NP_001 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAAR
10 20 30 40
60 70 80 90 100 110
pF1KB7 CALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERA
:.: : : .: ::::: :: : ..: ::..::::::
NP_001 CGLQGARRRAGGRR-----AGGGGPGGRPG---REP------------RQRHTANARERD
50 60 70 80
120 130 140 150 160 170
pF1KB7 RMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNL
: .. ::. :.: .: : : ::::..:::::::::.:: ..:
NP_001 RTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSG
90 100 110 120 130 140
180 190 200
pF1KB7 TWPFVVSGRPDSDTKEVSAANRLCGTTA
NP_001 PAFFHAARAGSPPPPPPPPPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
150 160 170 180 190 200
>>XP_006716679 (OMIM: 609067) PREDICTED: basic helix-loo (201 aa)
initn: 279 init1: 197 opt: 242 Z-score: 214.0 bits: 46.5 E(85289): 3.5e-05
Smith-Waterman score: 252; 37.5% identity (57.6% similar) in 144 aa overlap (22-163:8-131)
10 20 30 40 50
pF1KB7 MSTGSVSDPEEMELRGLQREYPVPASKR--PPLRGVERSYASPSDNSSAEEEDPDGEEER
:.: .. : . . .. ::.:...:. . :
XP_006 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAAR
10 20 30 40
60 70 80 90 100 110
pF1KB7 CALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERA
:.: : : .: ::::: :: : ..: ::..::::::
XP_006 CGLQGARRRAGGRR-----AGGGGPGGRPG---REP------------RQRHTANARERD
50 60 70 80
120 130 140 150 160 170
pF1KB7 RMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNL
: .. ::. :.: .: : : ::::..:::::::::.:: ..:
XP_006 RTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSG
90 100 110 120 130 140
180 190 200
pF1KB7 TWPFVVSGRPDSDTKEVSAANRLCGTTA
XP_006 PAFFHAARAGSPPPPPPPPPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
150 160 170 180 190 200
>>NP_476527 (OMIM: 200110,209885,227260,607556) twist-re (160 aa)
initn: 217 init1: 116 opt: 226 Z-score: 202.5 bits: 44.1 E(85289): 0.00015
Smith-Waterman score: 234; 36.6% identity (58.8% similar) in 153 aa overlap (37-184:7-147)
10 20 30 40 50 60
pF1KB7 SDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGS
: .:: :. .. ::. . . .:
NP_476 MEEGSSSPVSPVDSLGTSEEELERQPKRF-------
10 20
70 80 90 100 110 120
pF1KB7 AEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKA
: ::. . .. :. . : ::: :. : : :::: ::.::: : . :..:
NP_476 --GRKRRYSKKSSEDGSP-TPGKRGKKGSPSAQSFEEL-QSQRILANVRERQRTQSLNEA
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB7 FSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN-----GYVHPVNLTWP
:. :. .: .: : ::::..::.::. :: : :.:: :...: .:: :..
NP_476 FAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYA
90 100 110 120 130 140
190 200
pF1KB7 FVVSGRPDSDTKEVSAANRLCGTTA
: :
NP_476 FSVWRMEGAWSMSASH
150 160
>>NP_001258822 (OMIM: 200110,209885,227260,607556) twist (160 aa)
initn: 217 init1: 116 opt: 226 Z-score: 202.5 bits: 44.1 E(85289): 0.00015
Smith-Waterman score: 234; 36.6% identity (58.8% similar) in 153 aa overlap (37-184:7-147)
10 20 30 40 50 60
pF1KB7 SDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGS
: .:: :. .. ::. . . .:
NP_001 MEEGSSSPVSPVDSLGTSEEELERQPKRF-------
10 20
70 80 90 100 110 120
pF1KB7 AEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKA
: ::. . .. :. . : ::: :. : : :::: ::.::: : . :..:
NP_001 --GRKRRYSKKSSEDGSP-TPGKRGKKGSPSAQSFEEL-QSQRILANVRERQRTQSLNEA
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB7 FSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN-----GYVHPVNLTWP
:. :. .: .: : ::::..::.::. :: : :.:: :...: .:: :..
NP_001 FAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYA
90 100 110 120 130 140
190 200
pF1KB7 FVVSGRPDSDTKEVSAANRLCGTTA
: :
NP_001 FSVWRMEGAWSMSASH
150 160
206 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:41:58 2016 done: Fri Nov 4 08:41:59 2016
Total Scan time: 6.660 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]