Result of FASTA (omim) for
pFN21AB7296
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7296, 1333 aa
1>>>pF1KB7296 1333 - 1333 aa - 1333 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.8742+/-0.000557; mu= -33.3029+/- 0.035
mean_var=671.8879+/-139.979, 0's: 0 Z-trim(121.3): 160 B-trim: 297 in 1/59
Lambda= 0.049480
statistics sampled from 37478 (37656) to 37478 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.442), width: 16
Scan time: 19.490
The best scores are: opt bits E(85289)
NP_005624 (OMIM: 135300,182530,610733) son of seve (1333) 8954 655.7 6.4e-187
XP_011531364 (OMIM: 135300,182530,610733) PREDICTE (1326) 8763 642.0 8.1e-183
XP_011531366 (OMIM: 135300,182530,610733) PREDICTE (1276) 8577 628.7 7.8e-179
XP_005264572 (OMIM: 135300,182530,610733) PREDICTE (1318) 7500 551.9 1.1e-155
XP_011531368 (OMIM: 135300,182530,610733) PREDICTE ( 978) 6609 488.2 1.2e-136
NP_008870 (OMIM: 601247,616559) son of sevenless h (1332) 6229 461.1 2.3e-128
NP_722522 (OMIM: 606600) ras-specific guanine nucl ( 489) 531 54.1 2.8e-06
NP_001139120 (OMIM: 606600) ras-specific guanine n (1257) 531 54.4 6.1e-06
XP_016877945 (OMIM: 606600) PREDICTED: ras-specifi (1260) 531 54.4 6.1e-06
XP_016877944 (OMIM: 606600) PREDICTED: ras-specifi (1270) 531 54.4 6.2e-06
NP_002882 (OMIM: 606600) ras-specific guanine nucl (1273) 531 54.4 6.2e-06
XP_016865171 (OMIM: 606614) PREDICTED: ras-specifi (1142) 476 50.4 8.6e-05
NP_008840 (OMIM: 606614) ras-specific guanine nucl (1237) 476 50.4 9.2e-05
XP_016870839 (OMIM: 614444) PREDICTED: ras-specifi ( 384) 411 45.5 0.00086
NP_005303 (OMIM: 600303) rap guanine nucleotide ex (1077) 428 47.0 0.00088
NP_001291204 (OMIM: 600303) rap guanine nucleotide (1094) 428 47.0 0.00089
NP_941372 (OMIM: 600303) rap guanine nucleotide ex (1095) 428 47.0 0.00089
XP_006717137 (OMIM: 600303) PREDICTED: rap guanine (1100) 428 47.0 0.00089
XP_011516881 (OMIM: 600303) PREDICTED: rap guanine (1108) 428 47.0 0.0009
XP_011516880 (OMIM: 600303) PREDICTED: rap guanine (1139) 428 47.0 0.00092
XP_011516879 (OMIM: 600303) PREDICTED: rap guanine (1160) 428 47.0 0.00094
XP_011516878 (OMIM: 600303) PREDICTED: rap guanine (1161) 428 47.0 0.00094
XP_016870128 (OMIM: 600303) PREDICTED: rap guanine (1192) 428 47.0 0.00096
XP_016870127 (OMIM: 600303) PREDICTED: rap guanine (1194) 428 47.0 0.00096
XP_016870126 (OMIM: 600303) PREDICTED: rap guanine (1225) 428 47.0 0.00098
XP_005272248 (OMIM: 600303) PREDICTED: rap guanine (1226) 428 47.0 0.00098
XP_006717135 (OMIM: 600303) PREDICTED: rap guanine (1232) 428 47.0 0.00098
XP_016870125 (OMIM: 600303) PREDICTED: rap guanine (1233) 428 47.0 0.00098
XP_016870124 (OMIM: 600303) PREDICTED: rap guanine (1241) 428 47.0 0.00099
XP_016870123 (OMIM: 600303) PREDICTED: rap guanine (1241) 428 47.0 0.00099
XP_011516877 (OMIM: 600303) PREDICTED: rap guanine (1246) 428 47.0 0.00099
XP_011516876 (OMIM: 600303) PREDICTED: rap guanine (1247) 428 47.0 0.00099
XP_016870122 (OMIM: 600303) PREDICTED: rap guanine (1247) 428 47.0 0.00099
XP_011516875 (OMIM: 600303) PREDICTED: rap guanine (1255) 428 47.0 0.001
XP_005272243 (OMIM: 600303) PREDICTED: rap guanine (1264) 428 47.0 0.001
XP_006717130 (OMIM: 600303) PREDICTED: rap guanine (1270) 428 47.0 0.001
XP_011516874 (OMIM: 600303) PREDICTED: rap guanine (1272) 428 47.0 0.001
XP_011516873 (OMIM: 600303) PREDICTED: rap guanine (1273) 428 47.0 0.001
XP_011516872 (OMIM: 600303) PREDICTED: rap guanine (1277) 428 47.0 0.001
XP_011516871 (OMIM: 600303) PREDICTED: rap guanine (1278) 428 47.0 0.001
NP_001309253 (OMIM: 614444) ras-specific guanine n ( 514) 412 45.7 0.001
XP_016870837 (OMIM: 614444) PREDICTED: ras-specifi ( 527) 412 45.7 0.0011
XP_011517538 (OMIM: 614444) PREDICTED: ras-specifi ( 515) 408 45.4 0.0013
NP_001177657 (OMIM: 614444) ras-specific guanine n ( 529) 408 45.4 0.0013
NP_001177658 (OMIM: 614444) ras-specific guanine n ( 537) 408 45.4 0.0013
NP_001309249 (OMIM: 614444) ras-specific guanine n ( 537) 408 45.4 0.0013
NP_001309251 (OMIM: 614444) ras-specific guanine n ( 576) 406 45.3 0.0015
NP_001309250 (OMIM: 614444) ras-specific guanine n ( 584) 406 45.3 0.0016
NP_001177659 (OMIM: 614444) ras-specific guanine n ( 305) 392 44.1 0.0018
XP_011517535 (OMIM: 614444) PREDICTED: ras-specifi ( 585) 402 45.0 0.0019
>>NP_005624 (OMIM: 135300,182530,610733) son of sevenles (1333 aa)
initn: 8954 init1: 8954 opt: 8954 Z-score: 3476.8 bits: 655.7 E(85289): 6.4e-187
Smith-Waterman score: 8954; 100.0% identity (100.0% similar) in 1333 aa overlap (1-1333:1-1333)
10 20 30 40 50 60
pF1KB7 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB7 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB7 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB7 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB7 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
1270 1280 1290 1300 1310 1320
1330
pF1KB7 RDGPPLLENAHSS
:::::::::::::
NP_005 RDGPPLLENAHSS
1330
>>XP_011531364 (OMIM: 135300,182530,610733) PREDICTED: s (1326 aa)
initn: 8763 init1: 8763 opt: 8763 Z-score: 3403.1 bits: 642.0 E(85289): 8.1e-183
Smith-Waterman score: 8763; 99.9% identity (100.0% similar) in 1306 aa overlap (28-1333:21-1326)
10 20 30 40 50 60
pF1KB7 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
.::::::::::::::::::::::::::::::::
XP_011 MDTRLRTLEFILGRQCEFLNRKVQGQVHPTLESNDDALQYVEELILQLLNMLC
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB7 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB7 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB7 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB7 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB7 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB7 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB7 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB7 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB7 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB7 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB7 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB7 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB7 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB7 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
1260 1270 1280 1290 1300 1310
1330
pF1KB7 RDGPPLLENAHSS
:::::::::::::
XP_011 RDGPPLLENAHSS
1320
>>XP_011531366 (OMIM: 135300,182530,610733) PREDICTED: s (1276 aa)
initn: 8577 init1: 8577 opt: 8577 Z-score: 3331.6 bits: 628.7 E(85289): 7.8e-179
Smith-Waterman score: 8577; 100.0% identity (100.0% similar) in 1276 aa overlap (58-1333:1-1276)
30 40 50 60 70 80
pF1KB7 KKVQGQVHPTLESNDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAI
::::::::::::::::::::::::::::::
XP_011 MLCQAQPRSASDVEERVQKSFPHPIDKWAI
10 20 30
90 100 110 120 130 140
pF1KB7 ADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGN
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB7 YVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB7 FMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTV
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB7 EMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSI
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB7 GEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGM
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB7 EKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIME
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB7 GTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDT
400 410 420 430 440 450
510 520 530 540 550 560
pF1KB7 NEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQM
460 470 480 490 500 510
570 580 590 600 610 620
pF1KB7 RLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTF
520 530 540 550 560 570
630 640 650 660 670 680
pF1KB7 LTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQL
580 590 600 610 620 630
690 700 710 720 730 740
pF1KB7 RVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNG
640 650 660 670 680 690
750 760 770 780 790 800
pF1KB7 PGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGS
700 710 720 730 740 750
810 820 830 840 850 860
pF1KB7 VWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNN
760 770 780 790 800 810
870 880 890 900 910 920
pF1KB7 FNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV
820 830 840 850 860 870
930 940 950 960 970 980
pF1KB7 PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDI
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KB7 KRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRP
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KB7 GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDS
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KB7 DHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESS
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KB7 PSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFS
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KB7 SSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSI
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330
pF1KB7 AGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
1240 1250 1260 1270
>>XP_005264572 (OMIM: 135300,182530,610733) PREDICTED: s (1318 aa)
initn: 7553 init1: 7411 opt: 7500 Z-score: 2915.9 bits: 551.9 E(85289): 1.1e-155
Smith-Waterman score: 8811; 98.9% identity (98.9% similar) in 1333 aa overlap (1-1333:1-1318)
10 20 30 40 50 60
pF1KB7 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB7 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
::::::::::::::::::::::::::::::::::: ::::::::::
XP_005 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHS---------------RSASVSSISL
1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KB7 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KB7 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KB7 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
1250 1260 1270 1280 1290 1300
1330
pF1KB7 RDGPPLLENAHSS
:::::::::::::
XP_005 RDGPPLLENAHSS
1310
>>XP_011531368 (OMIM: 135300,182530,610733) PREDICTED: s (978 aa)
initn: 6609 init1: 6609 opt: 6609 Z-score: 2574.1 bits: 488.2 E(85289): 1.2e-136
Smith-Waterman score: 6609; 100.0% identity (100.0% similar) in 976 aa overlap (358-1333:3-978)
330 340 350 360 370 380
pF1KB7 GEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGM
::::::::::::::::::::::::::::::
XP_011 MGKQLEEKSEDQEDKECLKQAITALLNVQSGM
10 20 30
390 400 410 420 430 440
pF1KB7 EKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIME
40 50 60 70 80 90
450 460 470 480 490 500
pF1KB7 GTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDT
100 110 120 130 140 150
510 520 530 540 550 560
pF1KB7 NEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQM
160 170 180 190 200 210
570 580 590 600 610 620
pF1KB7 RLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTF
220 230 240 250 260 270
630 640 650 660 670 680
pF1KB7 LTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQL
280 290 300 310 320 330
690 700 710 720 730 740
pF1KB7 RVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNG
340 350 360 370 380 390
750 760 770 780 790 800
pF1KB7 PGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGS
400 410 420 430 440 450
810 820 830 840 850 860
pF1KB7 VWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNN
460 470 480 490 500 510
870 880 890 900 910 920
pF1KB7 FNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV
520 530 540 550 560 570
930 940 950 960 970 980
pF1KB7 PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDI
580 590 600 610 620 630
990 1000 1010 1020 1030 1040
pF1KB7 KRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRP
640 650 660 670 680 690
1050 1060 1070 1080 1090 1100
pF1KB7 GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDS
700 710 720 730 740 750
1110 1120 1130 1140 1150 1160
pF1KB7 DHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESS
760 770 780 790 800 810
1170 1180 1190 1200 1210 1220
pF1KB7 PSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFS
820 830 840 850 860 870
1230 1240 1250 1260 1270 1280
pF1KB7 SSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSI
880 890 900 910 920 930
1290 1300 1310 1320 1330
pF1KB7 AGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
940 950 960 970
>>NP_008870 (OMIM: 601247,616559) son of sevenless homol (1332 aa)
initn: 4614 init1: 4562 opt: 6229 Z-score: 2425.5 bits: 461.1 E(85289): 2.3e-128
Smith-Waterman score: 6229; 69.5% identity (85.6% similar) in 1351 aa overlap (1-1332:1-1330)
10 20 30 40 50 60
pF1KB7 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
:: :::::::::.:::::::: ::.::: :::::: .:...: :.::::.:::: ::
NP_008 MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
.::::...::::::::.:::::::::::::::::::::::::: :::.:::: :::::::
NP_008 MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
:.:..::.::::::::::::::::.:::: :::::::..:::::.::::::::::: ::
NP_008 KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQD-
130 140 150 160 170
190 200 210 220 230 240
pF1KB7 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
::...:: ..:::.::: .:::::.. .:: :::.::::.::::::: :.:. :::. .
NP_008 -DIGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
:.:.::: : :::::.::::: ::::::::::.:::::.:::::::::: ::::::. ..
NP_008 DIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
::: : ::..: . ...:..::..:::..::::::.::::::.:.::::: :::::::::
NP_008 DILSPEFHEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
. ::.:::.:::.::::::.:.:..:..: .. .:: .. .: :::.:...:.::::
NP_008 KACSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYSHQLRSKHLAIK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB7 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
:::::::::::::::::::::::::::: :::.:::::::::::::::: :: :::: ::
NP_008 KMNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB7 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
:: :.::::::::: :::.:: ::.:: :.:::::.. :::::.::.:::::::::::::
NP_008 PGYSSAEYRLKEKFVMRKIQICDKEDTCEHKHAFELVSKDENSIIFAAKSAEEKNNWMAA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB7 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
::::.:::::.:::: ..:.::.:. .:::: .::::. ::::::.::.:.: ..::::
NP_008 LISLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPI
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB7 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
::.:::.::::::::::::::::::::::::::::::::::::.::::::::::::.::.
NP_008 IKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB7 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
.:::.:.::.::.::::::::.::::::.::: :::::::::::::: ::.:.: ::..
NP_008 LAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB7 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
:::::::::::::.:::.::: :. :: .:::::.: :: .:::::.::..:::::.:::
NP_008 VRGKAMKKWVESIAKIIRRKKQAQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLH
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB7 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_008 PIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB7 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
:.::.::::::.:::::::::::.:::::::::.:::.:: ::::::::: . :..::
NP_008 EAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKI
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB7 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
:.:: :::.::.::::.::.:::::::::::::::::::::::: . ::..::.::::::
NP_008 LDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSK
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB7 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
::::::::::::::::::::::.: :..::::::::::.. :::::::::::::::::::
NP_008 RRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070
pF1KB7 PKPLPRFPKKYSYPLKSPGVRPSNPR----PGTMR-HPTPLQQEPRKISYSRIPESETES
: ::::.: .. :::::.::.. : ::.: :::::..:: :::.::: :.: ::
NP_008 CKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELES
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KB7 TASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASV
:.:::.:: :: ::: .:...:. .: : .: : ...: : :::. .:
NP_008 TVSAPTSPNTPSTPP----VSASSDLSVFLDVDLNSSCGS--NSIFAPVLLPHS-KSFFS
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KB7 SSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPR
: :: : ..: .:::.:::.. . ..: :: : :.::::::::: .::
NP_008 SCGSLHKLSEEPLIPPPLPPRKKFDH---DASNSKGNMKSDDDPPAIPPRQPPPPKVKPR
1140 1150 1160 1170 1180
1200 1210 1220 1230 1240
pF1KB7 YSIS----DRTSISDPPESP----PLLPPREPVRTPDVFSSSPLHLQPPPLG---KKSD-
. : : :: : : :: :.: :. : . :..::::::: . ::
NP_008 VPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDW
1190 1200 1210 1220 1230 1240
1250 1260 1270 1280 1290 1300
pF1KB7 -HGNAFFPNSPSPFTPPPPQTPSPHGTRR-HLPSPPLTQEVDLHSIAGPPVPPRQSTSQH
. . ::::: ::.::::. :: .. : ... .: .:::::::..: :
NP_008 LRDISTCPNSPS----TPPSTPSPRVPRRCYVLS---SSQNNLAHPPAPPVPPRQNSSPH
1250 1260 1270 1280 1290 1300
1310 1320 1330
pF1KB7 IPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
.::::::::::: .:: ..: ::::::..
NP_008 LPKLPPKTYKRELSHPPLYR--LPLLENAETPQ
1310 1320 1330
>>NP_722522 (OMIM: 606600) ras-specific guanine nucleoti (489 aa)
initn: 507 init1: 252 opt: 531 Z-score: 233.8 bits: 54.1 E(85289): 2.8e-06
Smith-Waterman score: 532; 28.2% identity (63.6% similar) in 376 aa overlap (653-1021:134-488)
630 640 650 660 670 680
pF1KB7 FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYI
:. . :... .. : . . ::..
NP_722 TSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFP--PDQRNGDKEFV
110 120 130 140 150 160
690 700 710 720 730
pF1KB7 --QPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG--KAMKKWVESITKIIQ
. . ::::: :::: .: ::: . : .. :. : . . . .. ..::
NP_722 IRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANII-
170 180 190 200 210 220
740 750 760 770 780 790
pF1KB7 RKKIARDNGPGHN-ITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYR
. ..... :: : ::.. .: ..: .:. . : :::.:::::. ...
NP_722 -RTLTQED-PGDNQITLEEITQMAEGVKAEP--FENHSAL-----EIAEQLTLLDHLVFK
230 240 250 260 270
800 810 820 830 840 850
pF1KB7 AVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIE
. :. :. : : .:. .: ..: .: .... . . :...:... ::... . .
NP_722 KIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVA
280 290 300 310 320 330
860 870 880 890 900 910
pF1KB7 ILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKY
. .. . :.:.:.:::..:.:: : ..:: .:. .. .. : .... ..: :: ..:.
NP_722 VADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNL
340 350 360 370 380 390
920 930 940 950 960 970
pF1KB7 LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
:.. .:::::..:.:::.. :::.:. . : :.:::: : ...: ::.:.:
NP_722 REALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTE-DG--LVNFSKMRMISHIIREIRQFQ
400 410 420 430 440
980 990 1000 1010 1020 1030
pF1KB7 NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
. : .. .. . ... . . . :..: :...::.:::. :
NP_722 QTAYKIEHQAKVTQYLLDQSFV---MDEE---SLYESSLRIEPKLPT
450 460 470 480
1040 1050 1060 1070 1080 1090
pF1KB7 KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA
>>NP_001139120 (OMIM: 606600) ras-specific guanine nucle (1257 aa)
initn: 499 init1: 252 opt: 531 Z-score: 227.6 bits: 54.4 E(85289): 6.1e-06
Smith-Waterman score: 532; 28.2% identity (63.6% similar) in 376 aa overlap (653-1021:902-1256)
630 640 650 660 670 680
pF1KB7 FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYI
:. . :... .. : . . ::..
NP_001 TSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFP--PDQRNGDKEFV
880 890 900 910 920
690 700 710 720 730
pF1KB7 --QPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG--KAMKKWVESITKIIQ
. . ::::: :::: .: ::: . : .. :. : . . . .. ..::
NP_001 IRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANII-
930 940 950 960 970 980
740 750 760 770 780 790
pF1KB7 RKKIARDNGPGHN-ITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYR
. ..... :: : ::.. .: ..: .:. . : :::.:::::. ...
NP_001 -RTLTQED-PGDNQITLEEITQMAEGVKAEP--FENHSAL-----EIAEQLTLLDHLVFK
990 1000 1010 1020 1030
800 810 820 830 840 850
pF1KB7 AVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIE
. :. :. : : .:. .: ..: .: .... . . :...:... ::... . .
NP_001 KIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVA
1040 1050 1060 1070 1080 1090
860 870 880 890 900 910
pF1KB7 ILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKY
. .. . :.:.:.:::..:.:: : ..:: .:. .. .. : .... ..: :: ..:.
NP_001 VADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNL
1100 1110 1120 1130 1140 1150
920 930 940 950 960 970
pF1KB7 LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
:.. .:::::..:.:::.. :::.:. . : :.:::: : ...: ::.:.:
NP_001 REALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTE-DG--LVNFSKMRMISHIIREIRQFQ
1160 1170 1180 1190 1200 1210
980 990 1000 1010 1020 1030
pF1KB7 NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
. : .. .. . ... . . . :..: :...::.:::. :
NP_001 QTAYKIEHQAKVTQYLLDQSFV---MDEE---SLYESSLRIEPKLPT
1220 1230 1240 1250
1040 1050 1060 1070 1080 1090
pF1KB7 KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA
>>XP_016877945 (OMIM: 606600) PREDICTED: ras-specific gu (1260 aa)
initn: 499 init1: 252 opt: 531 Z-score: 227.6 bits: 54.4 E(85289): 6.1e-06
Smith-Waterman score: 532; 28.2% identity (63.6% similar) in 376 aa overlap (653-1021:905-1259)
630 640 650 660 670 680
pF1KB7 FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYI
:. . :... .. : . . ::..
XP_016 TSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFP--PDQRNGDKEFV
880 890 900 910 920 930
690 700 710 720 730
pF1KB7 --QPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG--KAMKKWVESITKIIQ
. . ::::: :::: .: ::: . : .. :. : . . . .. ..::
XP_016 IRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANII-
940 950 960 970 980 990
740 750 760 770 780 790
pF1KB7 RKKIARDNGPGHN-ITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYR
. ..... :: : ::.. .: ..: .:. . : :::.:::::. ...
XP_016 -RTLTQED-PGDNQITLEEITQMAEGVKAEP--FENHSAL-----EIAEQLTLLDHLVFK
1000 1010 1020 1030 1040
800 810 820 830 840 850
pF1KB7 AVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIE
. :. :. : : .:. .: ..: .: .... . . :...:... ::... . .
XP_016 KIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVA
1050 1060 1070 1080 1090 1100
860 870 880 890 900 910
pF1KB7 ILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKY
. .. . :.:.:.:::..:.:: : ..:: .:. .. .. : .... ..: :: ..:.
XP_016 VADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNL
1110 1120 1130 1140 1150 1160
920 930 940 950 960 970
pF1KB7 LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
:.. .:::::..:.:::.. :::.:. . : :.:::: : ...: ::.:.:
XP_016 REALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTE-DG--LVNFSKMRMISHIIREIRQFQ
1170 1180 1190 1200 1210
980 990 1000 1010 1020 1030
pF1KB7 NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
. : .. .. . ... . . . :..: :...::.:::. :
XP_016 QTAYKIEHQAKVTQYLLDQSFV---MDEE---SLYESSLRIEPKLPT
1220 1230 1240 1250 1260
1040 1050 1060 1070 1080 1090
pF1KB7 KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA
>>XP_016877944 (OMIM: 606600) PREDICTED: ras-specific gu (1270 aa)
initn: 499 init1: 252 opt: 531 Z-score: 227.6 bits: 54.4 E(85289): 6.2e-06
Smith-Waterman score: 532; 28.2% identity (63.6% similar) in 376 aa overlap (653-1021:915-1269)
630 640 650 660 670 680
pF1KB7 FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYI
:. . :... .. : . . ::..
XP_016 TSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFP--PDQRNGDKEFV
890 900 910 920 930 940
690 700 710 720 730
pF1KB7 --QPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG--KAMKKWVESITKIIQ
. . ::::: :::: .: ::: . : .. :. : . . . .. ..::
XP_016 IRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANII-
950 960 970 980 990 1000
740 750 760 770 780 790
pF1KB7 RKKIARDNGPGHN-ITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYR
. ..... :: : ::.. .: ..: .:. . : :::.:::::. ...
XP_016 -RTLTQED-PGDNQITLEEITQMAEGVKAEP--FENHSAL-----EIAEQLTLLDHLVFK
1010 1020 1030 1040 1050
800 810 820 830 840 850
pF1KB7 AVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIE
. :. :. : : .:. .: ..: .: .... . . :...:... ::... . .
XP_016 KIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVA
1060 1070 1080 1090 1100 1110
860 870 880 890 900 910
pF1KB7 ILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKY
. .. . :.:.:.:::..:.:: : ..:: .:. .. .. : .... ..: :: ..:.
XP_016 VADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNL
1120 1130 1140 1150 1160 1170
920 930 940 950 960 970
pF1KB7 LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
:.. .:::::..:.:::.. :::.:. . : :.:::: : ...: ::.:.:
XP_016 REALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTE-DG--LVNFSKMRMISHIIREIRQFQ
1180 1190 1200 1210 1220
980 990 1000 1010 1020 1030
pF1KB7 NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
. : .. .. . ... . . . :..: :...::.:::. :
XP_016 QTAYKIEHQAKVTQYLLDQSFV---MDEE---SLYESSLRIEPKLPT
1230 1240 1250 1260 1270
1040 1050 1060 1070 1080 1090
pF1KB7 KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA
1333 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:39:26 2016 done: Fri Nov 4 06:39:29 2016
Total Scan time: 19.490 Total Display time: 0.590
Function used was FASTA [36.3.4 Apr, 2011]