Result of FASTA (omim) for
pFN21AB7232
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7232, 396 aa
1>>>pF1KB7232 396 - 396 aa - 396 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3647+/-0.000331; mu= 17.7020+/- 0.021
mean_var=77.9914+/-15.474, 0's: 0 Z-trim(117.1): 79 B-trim: 876 in 1/54
Lambda= 0.145228
statistics sampled from 28666 (28748) to 28666 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.337), width: 16
Scan time: 9.370
The best scores are: opt bits E(85289)
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 2695 573.9 2.3e-163
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 1676 360.2 3e-99
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 1548 333.6 5.3e-91
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 1548 333.6 5.3e-91
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 1548 333.6 5.3e-91
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 1548 333.6 5.3e-91
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 1497 322.8 7.6e-88
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 1497 322.8 7.6e-88
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 524 119.0 1.9e-26
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 497 113.4 1.2e-24
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 491 112.1 2.4e-24
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 488 111.3 2.5e-24
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 489 111.7 3.4e-24
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 488 111.5 4.1e-24
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 475 108.8 2.7e-23
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 473 108.4 3.9e-23
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 473 108.4 3.9e-23
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 473 108.4 3.9e-23
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 467 107.1 8.7e-23
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 450 103.5 9.8e-22
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 430 99.3 1.8e-20
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 414 96.0 2e-19
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 394 91.8 3.4e-18
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 393 91.6 3.9e-18
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 393 91.6 3.9e-18
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 393 91.6 4.2e-18
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 393 91.7 4.7e-18
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 390 91.0 6.5e-18
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 365 85.5 1.3e-16
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 365 85.7 1.9e-16
NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392) 360 84.7 4.4e-16
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 353 83.1 1.1e-15
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 352 83.0 1.3e-15
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 347 81.9 3e-15
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390) 328 77.9 4.5e-14
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391) 325 77.3 7e-14
XP_011540324 (OMIM: 602284) PREDICTED: bone morpho ( 357) 320 76.2 1.3e-13
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 306 73.3 1e-12
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 296 71.1 3.6e-12
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366) 296 71.2 4.5e-12
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366) 296 71.2 4.5e-12
NP_001275757 (OMIM: 601918) growth/differentiation ( 366) 296 71.2 4.5e-12
NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 296 71.2 4.5e-12
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366) 296 71.2 4.5e-12
NP_001275756 (OMIM: 601918) growth/differentiation ( 366) 296 71.2 4.5e-12
NP_001275755 (OMIM: 601918) growth/differentiation ( 366) 296 71.2 4.5e-12
NP_001275754 (OMIM: 601918) growth/differentiation ( 366) 296 71.2 4.5e-12
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366) 296 71.2 4.5e-12
NP_005250 (OMIM: 601788,614160) growth/differentia ( 375) 295 71.0 5.3e-12
NP_005251 (OMIM: 601918) growth/differentiation fa ( 454) 296 71.3 5.3e-12
>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene (396 aa)
initn: 2695 init1: 2695 opt: 2695 Z-score: 3053.8 bits: 573.9 E(85289): 2.3e-163
Smith-Waterman score: 2695; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KB7 MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 LPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKAC
310 320 330 340 350 360
370 380 390
pF1KB7 CVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
::::::::::::::::::::::::::::::::::::
NP_001 CVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
370 380 390
>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b (240 aa)
initn: 1676 init1: 1676 opt: 1676 Z-score: 1902.9 bits: 360.2 E(85289): 3e-99
Smith-Waterman score: 1676; 100.0% identity (100.0% similar) in 240 aa overlap (157-396:1-240)
130 140 150 160 170 180
pF1KB7 KTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKF
::::::::::::::::::::::::::::::
XP_011 MQDALGNNSSFHHRINIYEIIKPATANSKF
10 20 30
190 200 210 220 230 240
pF1KB7 PVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRI
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB7 SRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFS
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB7 DVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTEL
160 170 180 190 200 210
370 380 390
pF1KB7 SAISMLYLDENEKVVLKNYQDMVVEGCGCR
::::::::::::::::::::::::::::::
XP_011 SAISMLYLDENEKVVLKNYQDMVVEGCGCR
220 230 240
>>NP_570911 (OMIM: 112262,600625,607932) bone morphogene (408 aa)
initn: 947 init1: 687 opt: 1548 Z-score: 1754.8 bits: 333.6 E(85289): 5.3e-91
Smith-Waterman score: 1650; 62.8% identity (82.0% similar) in 411 aa overlap (1-396:1-408)
10 20 30 40 50
pF1KB7 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
:. :.: :...:: ::::::: :.:.:: :..: : ..:: :.: : :.: .::
NP_570 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
::.::::..:: ::..::.: :: :::: .:: : : . .. :: ::::::::
NP_570 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
:::::: ::..: :: ... ::.::::::: .: :.::::..::::.... . .:: :
NP_570 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFH-R
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
:::::..:: : . .:::::::::..:..:::.:::.:::.::: . . :.:...:
NP_570 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
:.::.. . . .:::::::: : .:.:.:::::::::::.:: : ..: ::. ::.
NP_570 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
:: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
NP_570 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
300 310 320 330 340 350
350 360 370 380 390
pF1KB7 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
:::::::::.::::::::::::::::::::: .::::::::.:::::::::
NP_570 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
360 370 380 390 400
>>NP_001193 (OMIM: 112262,600625,607932) bone morphogene (408 aa)
initn: 947 init1: 687 opt: 1548 Z-score: 1754.8 bits: 333.6 E(85289): 5.3e-91
Smith-Waterman score: 1650; 62.8% identity (82.0% similar) in 411 aa overlap (1-396:1-408)
10 20 30 40 50
pF1KB7 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
:. :.: :...:: ::::::: :.:.:: :..: : ..:: :.: : :.: .::
NP_001 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
::.::::..:: ::..::.: :: :::: .:: : : . .. :: ::::::::
NP_001 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
:::::: ::..: :: ... ::.::::::: .: :.::::..::::.... . .:: :
NP_001 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFH-R
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
:::::..:: : . .:::::::::..:..:::.:::.:::.::: . . :.:...:
NP_001 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
:.::.. . . .:::::::: : .:.:.:::::::::::.:: : ..: ::. ::.
NP_001 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
:: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
NP_001 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
300 310 320 330 340 350
350 360 370 380 390
pF1KB7 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
:::::::::.::::::::::::::::::::: .::::::::.:::::::::
NP_001 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
360 370 380 390 400
>>XP_016877092 (OMIM: 112262,600625,607932) PREDICTED: b (408 aa)
initn: 947 init1: 687 opt: 1548 Z-score: 1754.8 bits: 333.6 E(85289): 5.3e-91
Smith-Waterman score: 1650; 62.8% identity (82.0% similar) in 411 aa overlap (1-396:1-408)
10 20 30 40 50
pF1KB7 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
:. :.: :...:: ::::::: :.:.:: :..: : ..:: :.: : :.: .::
XP_016 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
::.::::..:: ::..::.: :: :::: .:: : : . .. :: ::::::::
XP_016 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
:::::: ::..: :: ... ::.::::::: .: :.::::..::::.... . .:: :
XP_016 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFH-R
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
:::::..:: : . .:::::::::..:..:::.:::.:::.::: . . :.:...:
XP_016 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
:.::.. . . .:::::::: : .:.:.:::::::::::.:: : ..: ::. ::.
XP_016 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
:: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
XP_016 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
300 310 320 330 340 350
350 360 370 380 390
pF1KB7 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
:::::::::.::::::::::::::::::::: .::::::::.:::::::::
XP_016 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
360 370 380 390 400
>>XP_005268072 (OMIM: 112262,600625,607932) PREDICTED: b (408 aa)
initn: 947 init1: 687 opt: 1548 Z-score: 1754.8 bits: 333.6 E(85289): 5.3e-91
Smith-Waterman score: 1650; 62.8% identity (82.0% similar) in 411 aa overlap (1-396:1-408)
10 20 30 40 50
pF1KB7 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
:. :.: :...:: ::::::: :.:.:: :..: : ..:: :.: : :.: .::
XP_005 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
::.::::..:: ::..::.: :: :::: .:: : : . .. :: ::::::::
XP_005 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
:::::: ::..: :: ... ::.::::::: .: :.::::..::::.... . .:: :
XP_005 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFH-R
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
:::::..:: : . .:::::::::..:..:::.:::.:::.::: . . :.:...:
XP_005 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
:.::.. . . .:::::::: : .:.:.:::::::::::.:: : ..: ::. ::.
XP_005 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
:: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
XP_005 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
300 310 320 330 340 350
350 360 370 380 390
pF1KB7 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
:::::::::.::::::::::::::::::::: .::::::::.:::::::::
XP_005 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
360 370 380 390 400
>>XP_016877094 (OMIM: 112262,600625,607932) PREDICTED: b (345 aa)
initn: 1508 init1: 687 opt: 1497 Z-score: 1698.0 bits: 322.8 E(85289): 7.6e-88
Smith-Waterman score: 1497; 65.4% identity (83.9% similar) in 347 aa overlap (60-396:1-345)
30 40 50 60 70 80
pF1KB7 RRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-
::::..:: ::..::.: :: :::: .::
XP_016 MFGLRRRPQPSKSAVIPDYMRDLYRLQSGE
10 20 30
90 100 110 120 130 140
pF1KB7 ----QPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEF
: : . .. :: :::::::::::::: ::..: :: ... ::.::::::: .:
XP_016 EEEEQIHSTGLEYP-ERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEV
40 50 60 70 80
150 160 170 180 190 200
pF1KB7 ITSAELQVFREQMQDALGNNSSFHHRINIYEIIKP-ATANSKFPVTRLLDTRLVNQNASR
:.::::..::::.... . .:: ::::::..:: : . .:::::::::..:..:
XP_016 ISSAELRLFREQVDQGPDWERGFH-RINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTR
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB7 WESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPL
::.:::.:::.::: . . :.:...::.::.. . . .:::::::: : .:.:.:::
XP_016 WETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPL
150 160 170 180 190 200
270 280 290 300 310
pF1KB7 LVTFGHDGKGHPL--HKREKRQAKHK-QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPG
::::::::.:: : ..: ::. ::. :: : :. .:.:: :::::::::::::::::::
XP_016 LVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPG
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB7 YHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEK
:.::::::.::::::::::::::::::::::::::.::::::::::::::::::::: .:
XP_016 YQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDK
270 280 290 300 310 320
380 390
pF1KB7 VVLKNYQDMVVEGCGCR
:::::::.:::::::::
XP_016 VVLKNYQEMVVEGCGCR
330 340
>>XP_016877093 (OMIM: 112262,600625,607932) PREDICTED: b (345 aa)
initn: 1508 init1: 687 opt: 1497 Z-score: 1698.0 bits: 322.8 E(85289): 7.6e-88
Smith-Waterman score: 1497; 65.4% identity (83.9% similar) in 347 aa overlap (60-396:1-345)
30 40 50 60 70 80
pF1KB7 RRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-
::::..:: ::..::.: :: :::: .::
XP_016 MFGLRRRPQPSKSAVIPDYMRDLYRLQSGE
10 20 30
90 100 110 120 130 140
pF1KB7 ----QPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEF
: : . .. :: :::::::::::::: ::..: :: ... ::.::::::: .:
XP_016 EEEEQIHSTGLEYP-ERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEV
40 50 60 70 80
150 160 170 180 190 200
pF1KB7 ITSAELQVFREQMQDALGNNSSFHHRINIYEIIKP-ATANSKFPVTRLLDTRLVNQNASR
:.::::..::::.... . .:: ::::::..:: : . .:::::::::..:..:
XP_016 ISSAELRLFREQVDQGPDWERGFH-RINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTR
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB7 WESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPL
::.:::.:::.::: . . :.:...::.::.. . . .:::::::: : .:.:.:::
XP_016 WETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPL
150 160 170 180 190 200
270 280 290 300 310
pF1KB7 LVTFGHDGKGHPL--HKREKRQAKHK-QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPG
::::::::.:: : ..: ::. ::. :: : :. .:.:: :::::::::::::::::::
XP_016 LVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPG
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB7 YHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEK
:.::::::.::::::::::::::::::::::::::.::::::::::::::::::::: .:
XP_016 YQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDK
270 280 290 300 310 320
380 390
pF1KB7 VVLKNYQDMVVEGCGCR
:::::::.:::::::::
XP_016 VVLKNYQEMVVEGCGCR
330 340
>>NP_065685 (OMIM: 606522,613702,613703,613704) growth/d (364 aa)
initn: 462 init1: 462 opt: 524 Z-score: 596.0 bits: 119.0 E(85289): 1.9e-26
Smith-Waterman score: 569; 31.7% identity (62.4% similar) in 356 aa overlap (54-395:26-363)
30 40 50 60 70 80
pF1KB7 LVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLY
: .:...:: . :.:.. :: . ..
NP_065 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF
10 20 30 40 50
90 100 110 120 130
pF1KB7 --RRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEELP----ETSGKTTRRFFFNLS
:. .. : ... . :.:..: : .... : ..:. . ..::::
NP_065 QDREAAATTGVSRDLCYVKELGVRGNVLR-FLPDQGFFLYPKKISQASSCLQKLLYFNLS
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB7 SIPTEEFITSAELQVFREQMQDALGNNSSFHH----RINIYEIIKPATANSKFPVT-RLL
.: .: .: :.: . : :: :: .. .. .. . .: . .. : ...
NP_065 AIKEREQLTLAQLGL------D-LGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMF
120 130 140 150 160
200 210 220 230 240
pF1KB7 DTRLVN--QNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQ-GVSKRHVRISRS
: : :.: ... .::. :. . . : :. .:. :... ::. .
NP_065 VLRSVPWPQGAVHFNLLDVAKD---WNDNPRKNFGLFLEILVKEDRDSGVNFQPEDTCAR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 LHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVG
:. . :. :.::.. : . :: .:..: : . :. :.:: :...: :.:
NP_065 LRCSLHA----SLLVVTLNPD-QCHP--SRKRRAAIPVPKLSCKNLCHRHQLFINFRDLG
230 240 250 260 270
310 320 330 340 350 360
pF1KB7 WNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAI
:. ::.:: :. : :::::::: :. :::.:.:..:.:...:. .::.: :.::.:: :
NP_065 WHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPI
280 290 300 310 320 330
370 380 390
pF1KB7 SMLYLDENEKVVLKNYQDMVVEGCGCR
:::: :.:..:.:..:.::::. :::
NP_065 SMLYQDNNDNVILRHYEDMVVDECGCG
340 350 360
>>NP_001709 (OMIM: 112266) bone morphogenetic protein 6 (513 aa)
initn: 703 init1: 313 opt: 497 Z-score: 563.3 bits: 113.4 E(85289): 1.2e-24
Smith-Waterman score: 637; 34.5% identity (59.9% similar) in 357 aa overlap (65-395:170-512)
40 50 60 70 80 90
pF1KB7 AASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSGQPG-SP
:: : :. : .: ::. : ::
NP_001 YNALSADNDEDGASEGERQQSWPHEAASSSQRRQPPPGAAHPLNRKSLLAPGSGSGGASP
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB7 APDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVF
. . . :. : :: . .. . ..: ::::.:: : .:.::....
NP_001 LTSAQDSAFLNDADMVMSFVNLVEYDKEFSPRQRHHKEFKFNLSQIPEGEVVTAAEFRIY
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB7 REQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAV
.. .. .. :.. . :.::.... . . :::::.: . : ::.: .
NP_001 KDCVMGSFKNQTFL---ISIYQVLQE--HQHRDSDLFLLDTRVVWASEEGWLEFDITATS
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB7 MRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKG
:.. . : :. . :. ..:: . : : . . .: .: :..:.: :
NP_001 NLWVVTPQHNMGLQLSVV---TRDGV-HVHPRAAGLVGRDGPYDKQ--PFMVAF---FKV
320 330 340 350 360
280 290 300
pF1KB7 HPLHKREKRQAKHKQRKR------------------------LKSSCKRHPLYVDFSDVG
.: : :.:. ..:.. ::..:..: :::.:.:.:
NP_001 SEVHVRTTRSASSRRRQQSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYVSFQDLG
370 380 390 400 410 420
310 320 330 340 350 360
pF1KB7 WNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSK-IPKACCVPTELSA
:.:::.:: :: : :: ::: ::: :.:.::::::::::. .: . .:: ::.::.:.:
NP_001 WQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNA
430 440 450 460 470 480
370 380 390
pF1KB7 ISMLYLDENEKVVLKNYQDMVVEGCGCR
::.::.:.: .:.::.:..:::..:::
NP_001 ISVLYFDDNSNVILKKYRNMVVRACGCH
490 500 510
396 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:09:25 2016 done: Fri Nov 4 06:09:27 2016
Total Scan time: 9.370 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]