Result of FASTA (omim) for
pFN21AB7204
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7204, 189 aa
1>>>pF1KB7204 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2636+/-0.000408; mu= 12.6960+/- 0.025
mean_var=58.2362+/-11.647, 0's: 0 Z-trim(110.9): 17 B-trim: 38 in 1/50
Lambda= 0.168065
statistics sampled from 19319 (19336) to 19319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.227), width: 16
Scan time: 5.580
The best scores are: opt bits E(85289)
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 1242 309.5 2.1e-84
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1106 276.5 1.8e-74
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 1082 270.7 1e-72
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1081 270.4 1.2e-72
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 1061 265.6 3.4e-71
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1053 263.6 1.3e-70
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1040 260.5 1.2e-69
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1039 260.3 1.4e-69
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 991 248.6 4.4e-66
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 975 244.7 6.5e-65
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 973 244.3 9.1e-65
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 944 237.2 1.2e-62
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 939 236.0 2.7e-62
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 681 173.5 1.9e-43
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 347 92.5 4.4e-19
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 340 90.8 1.6e-18
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 158 46.7 3e-05
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 1242 init1: 1242 opt: 1242 Z-score: 1636.3 bits: 309.5 E(85289): 2.1e-84
Smith-Waterman score: 1242; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
:::::::::
NP_002 LQKGLRRKD
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1106 init1: 1106 opt: 1106 Z-score: 1458.1 bits: 276.5 E(85289): 1.8e-74
Smith-Waterman score: 1106; 88.9% identity (95.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
::.: :::.:::::::::..:::::::::::::.::::::...::.:: ::.:::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::: ::::::: ::::::::::::::::::::: ::::::::::::::::::.:::::
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
::: :::::
NP_066 LQKRLRRKD
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1082 init1: 1082 opt: 1082 Z-score: 1426.6 bits: 270.7 E(85289): 1e-72
Smith-Waterman score: 1082; 87.3% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::.:::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
.::: ::::::::.::::..:::::::::::::.::::::...::.:: ::.::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::: ::::.:: ::::::::::::::::::::: ::::::::::::::::::.:::::
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
::: :::::
NP_067 LQKILRRKD
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1081 init1: 1081 opt: 1081 Z-score: 1425.3 bits: 270.4 E(85289): 1.2e-72
Smith-Waterman score: 1081; 87.3% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
:::::::::::::::::::::::::::::::::::::::::.:::::: :::::::.::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
.::: :::::::::::::..:::::::::::::.::::::...::.:: ::.:::::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::: ::::::: :::::::::::::::::::::. .:::::::::::::::::.:::::
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
::: :::::
NP_002 LQKRLRRKD
>>NP_066401 (OMIM: 147567) interferon alpha-7 precursor (189 aa)
initn: 1061 init1: 1061 opt: 1061 Z-score: 1399.1 bits: 265.6 E(85289): 3.4e-71
Smith-Waterman score: 1061; 85.7% identity (93.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
:: ::::::.:::::::::::::::::::::: ::::::::::::::: :::::::..:
NP_066 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
::.: :::.::::.::::..:::::::::::::.::::::...::.:: ::.:::::::
NP_066 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::: ::::::: ::::: :::::::::::::::: ::::::::::::::::::::::::
NP_066 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
:.:::::::
NP_066 LKKGLRRKD
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1074 init1: 1053 opt: 1053 Z-score: 1388.6 bits: 263.6 E(85289): 1.3e-70
Smith-Waterman score: 1053; 85.7% identity (92.6% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::.:::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
:::: :::::::::::::..::::::::::::::::::.:...::.:: :: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::: ::::::: ::: ::::::.:::::::::: ::::::::::::::::::::.:
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
.:. ::::.
NP_002 FQERLRRKE
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1040 init1: 1040 opt: 1040 Z-score: 1371.6 bits: 260.5 E(85289): 1.2e-69
Smith-Waterman score: 1040; 83.6% identity (93.1% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
::: :.:.::..::: :: :::::.: :::::.:::.:.:.::: ::: :::::::.::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
:::: :::::::::::::..:::.::::::::::.::::::::::.:::::::::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::: ::::::: ::::::::::.::::::::::: ::::::::::::::::::.:::::
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
::: :::::
NP_002 LQKRLRRKD
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1039 init1: 1039 opt: 1039 Z-score: 1370.3 bits: 260.3 E(85289): 1.4e-69
Smith-Waterman score: 1039; 82.5% identity (93.1% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
::: : ::::..::. ::::::::::::::::.:::.:...::::::: :::::::.:::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
:::: :::::::::::::..::::::::::::::::::.:::::::::: ::.:::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::. ::::::. ::: ::::.:::::::::::: ::::::::::::::::::::.:.:
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
::. ::::.
NP_002 LQERLRRKE
>>NP_000596 (OMIM: 147562) interferon alpha-2 precursor (188 aa)
initn: 989 init1: 654 opt: 991 Z-score: 1307.4 bits: 248.6 E(85289): 4.4e-66
Smith-Waterman score: 991; 81.0% identity (91.0% similar) in 189 aa overlap (1-189:1-188)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
:::.:.::.:.:::: :: ::.:::::::::::.::.:.::::: ::: :::::::.:::
NP_000 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
:::: : :::::::..: ..:::::: :::::::::::::::::::::: ::.:::::::
NP_000 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
70 80 90 100 110
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::: : ::: : ::.:::::::::::::::::: ::::::::::::::::::::.:::
NP_000 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
120 130 140 150 160 170
pF1KB7 LQKGLRRKD
::..:: :.
NP_000 LQESLRSKE
180
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 975 init1: 975 opt: 975 Z-score: 1286.4 bits: 244.7 E(85289): 6.5e-65
Smith-Waterman score: 975; 79.9% identity (88.9% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
::: :.::::..::: :: ::: ::::::::::.::...::::: ::: :::::::.::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
:::: :::::::::.:::..::.::::::::::::::.:::: ::::.: ::.:::::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
::: ::: : ::::::::::::::::::::: :::::::::::::::::::: : :
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
pF1KB7 LQKGLRRKD
::. ::::.
NP_066 LQERLRRKE
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:56:37 2016 done: Fri Nov 4 05:56:37 2016
Total Scan time: 5.580 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]