Result of FASTA (omim) for
pFN21AB7062
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7062, 664 aa
1>>>pF1KB7062 664 - 664 aa - 664 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0438+/-0.000584; mu= 22.1835+/- 0.036
mean_var=111.6813+/-23.723, 0's: 0 Z-trim(108.7): 205 B-trim: 748 in 1/47
Lambda= 0.121362
statistics sampled from 16508 (16758) to 16508 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.531), E-opt: 0.2 (0.196), width: 16
Scan time: 10.180
The best scores are: opt bits E(85289)
NP_009149 (OMIM: 144700,603046) E3 ubiquitin-prote ( 664) 4406 783.7 0
XP_016868491 (OMIM: 144700,603046) PREDICTED: E3 u ( 537) 3575 638.1 2.4e-182
NP_115807 (OMIM: 608046) E3 ubiquitin-protein liga ( 616) 264 58.5 8.6e-08
XP_011543605 (OMIM: 608046) PREDICTED: E3 ubiquiti ( 617) 264 58.5 8.6e-08
NP_757385 (OMIM: 608046) E3 ubiquitin-protein liga ( 617) 264 58.5 8.6e-08
NP_001310441 (OMIM: 603243) E3 ubiquitin-protein l ( 675) 235 53.5 3.1e-06
NP_001310440 (OMIM: 603243) E3 ubiquitin-protein l ( 548) 216 50.0 2.7e-05
XP_005255947 (OMIM: 603243) PREDICTED: E3 ubiquiti ( 548) 216 50.0 2.7e-05
NP_001135 (OMIM: 603243) E3 ubiquitin-protein liga ( 643) 216 50.1 3e-05
XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193) 201 46.8 8.9e-05
XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250) 189 44.9 0.00045
XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 189 44.9 0.00046
XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 189 44.9 0.00046
XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 189 44.9 0.00046
XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 189 44.9 0.00046
XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 189 44.9 0.00046
XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 189 44.9 0.00046
NP_057209 (OMIM: 615172) RING finger and transmemb ( 435) 190 45.3 0.00055
XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 189 45.1 0.00058
NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 189 45.1 0.00058
XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 189 45.1 0.00058
XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 189 45.1 0.00058
NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 189 45.1 0.00058
XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 189 45.1 0.00058
NP_009150 (OMIM: 612489) RING finger protein 24 is ( 148) 181 43.2 0.00085
NP_001308678 (OMIM: 612489) RING finger protein 24 ( 148) 181 43.2 0.00085
NP_001127809 (OMIM: 612489) RING finger protein 24 ( 148) 181 43.2 0.00085
XP_011527448 (OMIM: 612489) PREDICTED: RING finger ( 163) 181 43.2 0.00091
NP_001127810 (OMIM: 612489) RING finger protein 24 ( 169) 181 43.2 0.00093
XP_011527447 (OMIM: 612489) PREDICTED: RING finger ( 169) 181 43.2 0.00093
XP_016883110 (OMIM: 612489) PREDICTED: RING finger ( 169) 181 43.2 0.00093
XP_016883109 (OMIM: 612489) PREDICTED: RING finger ( 169) 181 43.2 0.00093
NP_057578 (OMIM: 612490) E3 ubiquitin-protein liga ( 153) 171 41.4 0.0029
NP_078815 (OMIM: 300439) E3 ubiquitin-protein liga ( 402) 174 42.5 0.0037
NP_919445 (OMIM: 300439) E3 ubiquitin-protein liga ( 428) 174 42.5 0.0038
XP_005247976 (OMIM: 608672) PREDICTED: E3 ubiquiti (1002) 178 43.7 0.004
NP_859061 (OMIM: 612063) E3 ubiquitin-protein liga ( 429) 173 42.4 0.0043
XP_005247974 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 178 43.8 0.0044
XP_005247975 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 178 43.8 0.0044
XP_016863029 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 178 43.8 0.0044
NP_055463 (OMIM: 608672) E3 ubiquitin-protein liga (1208) 178 43.8 0.0044
XP_005247973 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 178 43.8 0.0044
XP_005247971 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 178 43.8 0.0044
XP_005247972 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 178 43.8 0.0044
XP_016869785 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402) 170 41.8 0.006
XP_016869786 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402) 170 41.8 0.006
XP_011516015 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 170 41.8 0.0062
XP_016869784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 170 41.8 0.0062
NP_919313 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 170 41.8 0.0062
XP_011516014 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 170 41.8 0.0062
>>NP_009149 (OMIM: 144700,603046) E3 ubiquitin-protein l (664 aa)
initn: 4406 init1: 4406 opt: 4406 Z-score: 4179.9 bits: 783.7 E(85289): 0
Smith-Waterman score: 4406; 100.0% identity (100.0% similar) in 664 aa overlap (1-664:1-664)
10 20 30 40 50 60
pF1KB7 MAAVGPPQQQVRMAHQQVWAALEVALRVPCLYIIDAIFNSYPDSSQSRFCIVLQIFLRLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MAAVGPPQQQVRMAHQQVWAALEVALRVPCLYIIDAIFNSYPDSSQSRFCIVLQIFLRLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GVFASSIVLILSQRSLFKFYTYSSAFLLAATSVLVNYYASLHIDFYGAYNTSAFGIELLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GVFASSIVLILSQRSLFKFYTYSSAFLLAATSVLVNYYASLHIDFYGAYNTSAFGIELLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKGPSLWMALIVLQLTFGIGYVTLLQIHSIYSQLIILDLLVPVIGLITELPLHIRETLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RKGPSLWMALIVLQLTFGIGYVTLLQIHSIYSQLIILDLLVPVIGLITELPLHIRETLLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TSSLILTLNTVFVLAVKLKWFYYSTRYVYLLVRHMYRIYGLQLLMEDTWKRIRFPDILRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TSSLILTLNTVFVLAVKLKWFYYSTRYVYLLVRHMYRIYGLQLLMEDTWKRIRFPDILRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 FWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLICNLIISGCDSTLTVLGMSAVISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLICNLIISGCDSTLTVLGMSAVISS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 TAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWHHYALNTWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWHHYALNTWL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 FAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEFIFGVVMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEFIFGVVMF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 GNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSLPEIKGSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSLPEIKGSRL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 QEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIKDNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIKDNSN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 VSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAAEEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAAEEFN
610 620 630 640 650 660
pF1KB7 DDTD
::::
NP_009 DDTD
>>XP_016868491 (OMIM: 144700,603046) PREDICTED: E3 ubiqu (537 aa)
initn: 3575 init1: 3575 opt: 3575 Z-score: 3394.6 bits: 638.1 E(85289): 2.4e-182
Smith-Waterman score: 3575; 100.0% identity (100.0% similar) in 537 aa overlap (128-664:1-537)
100 110 120 130 140 150
pF1KB7 YASLHIDFYGAYNTSAFGIELLPRKGPSLWMALIVLQLTFGIGYVTLLQIHSIYSQLIIL
::::::::::::::::::::::::::::::
XP_016 MALIVLQLTFGIGYVTLLQIHSIYSQLIIL
10 20 30
160 170 180 190 200 210
pF1KB7 DLLVPVIGLITELPLHIRETLLFTSSLILTLNTVFVLAVKLKWFYYSTRYVYLLVRHMYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLVPVIGLITELPLHIRETLLFTSSLILTLNTVFVLAVKLKWFYYSTRYVYLLVRHMYR
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB7 IYGLQLLMEDTWKRIRFPDILRVFWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGLQLLMEDTWKRIRFPDILRVFWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLI
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB7 CNLIISGCDSTLTVLGMSAVISSVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNLIISGCDSTLTVLGMSAVISSVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQ
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB7 TGLSGLRPEERLIRLSRNMCLLLTAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGLSGLRPEERLIRLSRNMCLLLTAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSA
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB7 CLFILPVLLSYVLWHHYALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLFILPVLLSYVLWHHYALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKL
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB7 DDYVYYVRSTGSIIEFIFGVVMFGNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYVYYVRSTGSIIEFIFGVVMFGNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWK
340 350 360 370 380 390
520 530 540 550 560 570
pF1KB7 TFMNRRTAVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFMNRRTAVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLY
400 410 420 430 440 450
580 590 600 610 620 630
pF1KB7 IQDTCPMCHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQDTCPMCHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDC
460 470 480 490 500 510
640 650 660
pF1KB7 DDDVQRERNGVIQHTGAAAEEFNDDTD
:::::::::::::::::::::::::::
XP_016 DDDVQRERNGVIQHTGAAAEEFNDDTD
520 530
>>NP_115807 (OMIM: 608046) E3 ubiquitin-protein ligase s (616 aa)
initn: 256 init1: 222 opt: 264 Z-score: 260.9 bits: 58.5 E(85289): 8.6e-08
Smith-Waterman score: 264; 27.6% identity (57.6% similar) in 203 aa overlap (395-589:141-333)
370 380 390 400 410 420
pF1KB7 HFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWH--HYALNTWLFA
. . .:.: .: . : : :. .
NP_115 LFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASV
120 130 140 150 160 170
430 440 450 460 470
pF1KB7 VTAFCVELCLKVIVSLTV---YTLFMIDGYYNVLWEKLDDYVYYVRS-TGSIIEFIFGVV
.: : . . . ::. :.: .: . :.. :. :.. :: : ... .
NP_115 QLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAF
180 190 200 210 220 230
480 490 500 510 520 530
pF1KB7 MFGNGAYTMMFESGSKIRAF-MMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSL-PEIK
: :.:. :...: .. .. .. . : :.. . : :....:.: :.
NP_115 M------TIMI----KVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDAT
240 250 260 270 280
540 550 560 570 580 590
pF1KB7 GSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIK
.:: ...:: :: .:..:.:. :::: ::. :::.:. :.::: :.. :
NP_115 PEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPA
290 300 310 320 330 340
600 610 620 630 640 650
pF1KB7 DNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAA
NP_115 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS
350 360 370 380 390 400
>>XP_011543605 (OMIM: 608046) PREDICTED: E3 ubiquitin-pr (617 aa)
initn: 256 init1: 222 opt: 264 Z-score: 260.8 bits: 58.5 E(85289): 8.6e-08
Smith-Waterman score: 264; 27.6% identity (57.6% similar) in 203 aa overlap (395-589:141-333)
370 380 390 400 410 420
pF1KB7 HFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWH--HYALNTWLFA
. . .:.: .: . : : :. .
XP_011 LFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASV
120 130 140 150 160 170
430 440 450 460 470
pF1KB7 VTAFCVELCLKVIVSLTV---YTLFMIDGYYNVLWEKLDDYVYYVRS-TGSIIEFIFGVV
.: : . . . ::. :.: .: . :.. :. :.. :: : ... .
XP_011 QLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAF
180 190 200 210 220 230
480 490 500 510 520 530
pF1KB7 MFGNGAYTMMFESGSKIRAF-MMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSL-PEIK
: :.:. :...: .. .. .. . : :.. . : :....:.: :.
XP_011 M------TIMI----KVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDAT
240 250 260 270 280
540 550 560 570 580 590
pF1KB7 GSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIK
.:: ...:: :: .:..:.:. :::: ::. :::.:. :.::: :.. :
XP_011 PEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPA
290 300 310 320 330 340
600 610 620 630 640 650
pF1KB7 DNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAA
XP_011 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS
350 360 370 380 390 400
>>NP_757385 (OMIM: 608046) E3 ubiquitin-protein ligase s (617 aa)
initn: 256 init1: 222 opt: 264 Z-score: 260.8 bits: 58.5 E(85289): 8.6e-08
Smith-Waterman score: 264; 27.6% identity (57.6% similar) in 203 aa overlap (395-589:141-333)
370 380 390 400 410 420
pF1KB7 HFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWH--HYALNTWLFA
. . .:.: .: . : : :. .
NP_757 LFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASV
120 130 140 150 160 170
430 440 450 460 470
pF1KB7 VTAFCVELCLKVIVSLTV---YTLFMIDGYYNVLWEKLDDYVYYVRS-TGSIIEFIFGVV
.: : . . . ::. :.: .: . :.. :. :.. :: : ... .
NP_757 QLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAF
180 190 200 210 220 230
480 490 500 510 520 530
pF1KB7 MFGNGAYTMMFESGSKIRAF-MMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSL-PEIK
: :.:. :...: .. .. .. . : :.. . : :....:.: :.
NP_757 M------TIMI----KVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDAT
240 250 260 270 280
540 550 560 570 580 590
pF1KB7 GSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIK
.:: ...:: :: .:..:.:. :::: ::. :::.:. :.::: :.. :
NP_757 PEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPA
290 300 310 320 330 340
600 610 620 630 640 650
pF1KB7 DNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAA
NP_757 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS
350 360 370 380 390 400
>>NP_001310441 (OMIM: 603243) E3 ubiquitin-protein ligas (675 aa)
initn: 208 init1: 143 opt: 235 Z-score: 233.0 bits: 53.5 E(85289): 3.1e-06
Smith-Waterman score: 240; 23.8% identity (52.1% similar) in 353 aa overlap (330-664:126-453)
300 310 320 330 340 350
pF1KB7 SVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLL
.:. . . :. ... :... ::
NP_001 MLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVV----MWCLW
100 110 120 130 140 150
360 370 380 390 400 410
pF1KB7 LTAV--LHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFI----LPVLLSYVLWHH
.... ::.. . . :: : .. . : :: . . ... : .. : . . :
NP_001 FAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTH
160 170 180 190 200 210
420 430 440 450 460 470
pF1KB7 YALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEF
...: : ..: . . ... . :.. . : .. :: :::: : ..:.
NP_001 -GMHTLAF-MAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY---TDFVMEL
220 230 240 250 260
480 490 500 510 520
pF1KB7 IFGVVMFGNGAYTMMFE----SGSKIRAFMMCLHAYFNIYLQA---KNGWKTF--MNRRT
. . . . . ..: : ... ::. . . .. . :: .. :. :
NP_001 TLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARF
270 280 290 300 310 320
530 540 550 560 570 580
pF1KB7 AVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPM
:: . :: .: :: ::::. . .:: ::.: :: :::.:: . .::
NP_001 AV----ATPE----ELAVNNDDCAICW-DSMQAARKLPCGHLFHNSCLRSWLEQDTSCPT
330 340 350 360 370
590 600 610 620 630 640
pF1KB7 CHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDST---DCDDDV
:.... .: ::. : ... .. :. : ::::. .::. . : ::.
NP_001 CRMSL----NIADNNRVREEH---QGENLDENLVPVAAAEGRPRLNQHNHFFHFDGDDSS
380 390 400 410 420 430
650 660
pF1KB7 QRERNGVIQHTGAAAEEFNDDTD
.: .: .: ..:::
NP_001 MRVTAPEDVPVGQEVEVVDSDTDAPDLWSRIASWLPSFSVEVMHTTNILGITQASNSQLN
440 450 460 470 480 490
>>NP_001310440 (OMIM: 603243) E3 ubiquitin-protein ligas (548 aa)
initn: 208 init1: 143 opt: 216 Z-score: 216.0 bits: 50.0 E(85289): 2.7e-05
Smith-Waterman score: 221; 23.5% identity (53.0% similar) in 319 aa overlap (330-633:31-324)
300 310 320 330 340 350
pF1KB7 SVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLL
.:. . . :. ... :... ::
NP_001 MLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVM----WCLW
10 20 30 40 50
360 370 380 390 400 410
pF1KB7 LTAV--LHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFI----LPVLLSYVLWHH
.... ::.. . . :: : .. . : :: . . ... : .. : . . :
NP_001 FAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTH
60 70 80 90 100 110
420 430 440 450 460 470
pF1KB7 YALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEF
...: : ..: . . ... . :.. . : .. :: :::: : ..:.
NP_001 -GMHTLAF-MAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY---TDFVMEL
120 130 140 150 160 170
480 490 500 510 520
pF1KB7 IFGVVMFGNGAYTMMFE----SGSKIRAFMMCLHAYFNIYLQA---KNGWKTF--MNRRT
. . . . . ..: : ... ::. . . .. . :: .. :. :
NP_001 TLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARF
180 190 200 210 220 230
530 540 550 560 570 580
pF1KB7 AVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPM
:: . :: .: :: ::::. . .:: ::.: :: :::.:: . .::
NP_001 AV----ATPE----ELAVNNDDCAICW-DSMQAARKLPCGHLFHNSCLRSWLEQDTSCPT
240 250 260 270 280
590 600 610 620 630 640
pF1KB7 CHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRE
:.... .: ::. : ... .. :. : ::::. .::. .
NP_001 CRMSL----NIADNNRVREEH---QGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIA
290 300 310 320 330
650 660
pF1KB7 RNGVIQHTGAAAEEFNDDTD
NP_001 SWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEITT
340 350 360 370 380 390
>>XP_005255947 (OMIM: 603243) PREDICTED: E3 ubiquitin-pr (548 aa)
initn: 208 init1: 143 opt: 216 Z-score: 216.0 bits: 50.0 E(85289): 2.7e-05
Smith-Waterman score: 221; 23.5% identity (53.0% similar) in 319 aa overlap (330-633:31-324)
300 310 320 330 340 350
pF1KB7 SVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLL
.:. . . :. ... :... ::
XP_005 MLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVM----WCLW
10 20 30 40 50
360 370 380 390 400 410
pF1KB7 LTAV--LHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFI----LPVLLSYVLWHH
.... ::.. . . :: : .. . : :: . . ... : .. : . . :
XP_005 FAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTH
60 70 80 90 100 110
420 430 440 450 460 470
pF1KB7 YALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEF
...: : ..: . . ... . :.. . : .. :: :::: : ..:.
XP_005 -GMHTLAF-MAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY---TDFVMEL
120 130 140 150 160 170
480 490 500 510 520
pF1KB7 IFGVVMFGNGAYTMMFE----SGSKIRAFMMCLHAYFNIYLQA---KNGWKTF--MNRRT
. . . . . ..: : ... ::. . . .. . :: .. :. :
XP_005 TLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARF
180 190 200 210 220 230
530 540 550 560 570 580
pF1KB7 AVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPM
:: . :: .: :: ::::. . .:: ::.: :: :::.:: . .::
XP_005 AV----ATPE----ELAVNNDDCAICW-DSMQAARKLPCGHLFHNSCLRSWLEQDTSCPT
240 250 260 270 280
590 600 610 620 630 640
pF1KB7 CHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRE
:.... .: ::. : ... .. :. : ::::. .::. .
XP_005 CRMSL----NIADNNRVREEH---QGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIA
290 300 310 320 330
650 660
pF1KB7 RNGVIQHTGAAAEEFNDDTD
XP_005 SWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEITT
340 350 360 370 380 390
>>NP_001135 (OMIM: 603243) E3 ubiquitin-protein ligase A (643 aa)
initn: 208 init1: 143 opt: 216 Z-score: 215.2 bits: 50.1 E(85289): 3e-05
Smith-Waterman score: 221; 23.5% identity (53.0% similar) in 319 aa overlap (330-633:126-419)
300 310 320 330 340 350
pF1KB7 SVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLL
.:. . . :. ... :... ::
NP_001 MLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVM----WCLW
100 110 120 130 140 150
360 370 380 390 400 410
pF1KB7 LTAV--LHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFI----LPVLLSYVLWHH
.... ::.. . . :: : .. . : :: . . ... : .. : . . :
NP_001 FAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTH
160 170 180 190 200 210
420 430 440 450 460 470
pF1KB7 YALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEF
...: : ..: . . ... . :.. . : .. :: :::: : ..:.
NP_001 -GMHTLAF-MAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY---TDFVMEL
220 230 240 250 260
480 490 500 510 520
pF1KB7 IFGVVMFGNGAYTMMFE----SGSKIRAFMMCLHAYFNIYLQA---KNGWKTF--MNRRT
. . . . . ..: : ... ::. . . .. . :: .. :. :
NP_001 TLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARF
270 280 290 300 310 320
530 540 550 560 570 580
pF1KB7 AVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPM
:: . :: .: :: ::::. . .:: ::.: :: :::.:: . .::
NP_001 AV----ATPE----ELAVNNDDCAICW-DSMQAARKLPCGHLFHNSCLRSWLEQDTSCPT
330 340 350 360 370
590 600 610 620 630 640
pF1KB7 CHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRE
:.... .: ::. : ... .. :. : ::::. .::. .
NP_001 CRMSL----NIADNNRVREEH---QGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIA
380 390 400 410 420 430
650 660
pF1KB7 RNGVIQHTGAAAEEFNDDTD
NP_001 SWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEITT
440 450 460 470 480 490
>>XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquitin-pr (193 aa)
initn: 176 init1: 84 opt: 201 Z-score: 206.8 bits: 46.8 E(85289): 8.9e-05
Smith-Waterman score: 214; 31.4% identity (52.9% similar) in 153 aa overlap (501-640:5-156)
480 490 500 510 520
pF1KB7 IEFIFGVVMFGNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWKTFMNRRTAVKK--
:.. :..: .: ::. ..:
XP_016 MDICCMEICFHFYWITKFVQDRHRARRNRLRKDQ
10 20 30
530 540 550 560 570 580
pF1KB7 INSLPEIKGSRLQEINDVCAICYHEFTTSA--RITPCNHYFHALCLRKWLY-IQDTCPMC
...:: : .. .: :::::: :. . :: ::.: .: :. :: . :::.:
XP_016 LKKLPVHKFKKGDEY-DVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVC
40 50 60 70 80 90
590 600 610 620 630
pF1KB7 HQKVYIE----DDIKDNSNVSNNNGFIPPNETPEEAVRE----AAAESDRELNEDDSTDC
.::: :. :.:. :. : : .: : .:: . : .:.:
XP_016 KQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDY
100 110 120 130 140 150
640 650 660
pF1KB7 DDDVQRERNGVIQHTGAAAEEFNDDTD
..:
XP_016 EEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
160 170 180 190
664 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 04:27:07 2016 done: Fri Nov 4 04:27:09 2016
Total Scan time: 10.180 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]