Result of FASTA (omim) for
pFN21AB5400
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5400, 471 aa
1>>>pF1KB5400 471 - 471 aa - 471 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0871+/-0.000383; mu= 12.9309+/- 0.024
mean_var=402.1619+/-83.679, 0's: 0 Z-trim(124.2): 54 B-trim: 2640 in 2/60
Lambda= 0.063955
statistics sampled from 45217 (45286) to 45217 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.531), width: 16
Scan time: 11.070
The best scores are: opt bits E(85289)
NP_031389 (OMIM: 300084,300967) non-POU domain-con ( 471) 3200 309.0 1.8e-83
NP_001138880 (OMIM: 300084,300967) non-POU domain- ( 471) 3200 309.0 1.8e-83
NP_001138881 (OMIM: 300084,300967) non-POU domain- ( 471) 3200 309.0 1.8e-83
NP_001138882 (OMIM: 300084,300967) non-POU domain- ( 382) 2567 250.4 6.3e-66
XP_011533439 (OMIM: 612408) PREDICTED: paraspeckle ( 469) 1776 177.6 6.6e-44
XP_006719907 (OMIM: 612408) PREDICTED: paraspeckle ( 523) 1773 177.4 8.4e-44
NP_001035879 (OMIM: 612408) paraspeckle component ( 523) 1773 177.4 8.4e-44
XP_016857543 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1716 172.3 3.8e-42
XP_005271170 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1716 172.3 3.8e-42
XP_005271169 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1716 172.3 3.8e-42
XP_016857542 (OMIM: 605199) PREDICTED: splicing fa ( 707) 1716 172.3 3.8e-42
NP_005057 (OMIM: 605199) splicing factor, proline- ( 707) 1716 172.3 3.8e-42
XP_005271172 (OMIM: 605199) PREDICTED: splicing fa ( 669) 1696 170.4 1.3e-41
XP_011540252 (OMIM: 605199) PREDICTED: splicing fa ( 679) 1696 170.5 1.3e-41
XP_011533444 (OMIM: 612408) PREDICTED: paraspeckle ( 406) 1660 166.8 1e-40
XP_016876139 (OMIM: 612408) PREDICTED: paraspeckle ( 393) 1655 166.3 1.4e-40
XP_011533443 (OMIM: 612408) PREDICTED: paraspeckle ( 409) 1655 166.3 1.4e-40
XP_011533442 (OMIM: 612408) PREDICTED: paraspeckle ( 417) 1655 166.3 1.4e-40
XP_011533441 (OMIM: 612408) PREDICTED: paraspeckle ( 417) 1655 166.3 1.4e-40
XP_011533440 (OMIM: 612408) PREDICTED: paraspeckle ( 447) 1655 166.4 1.5e-40
>>NP_031389 (OMIM: 300084,300967) non-POU domain-contain (471 aa)
initn: 3200 init1: 3200 opt: 3200 Z-score: 1619.4 bits: 309.0 E(85289): 1.8e-83
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)
10 20 30 40 50 60
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
430 440 450 460 470
>>NP_001138880 (OMIM: 300084,300967) non-POU domain-cont (471 aa)
initn: 3200 init1: 3200 opt: 3200 Z-score: 1619.4 bits: 309.0 E(85289): 1.8e-83
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)
10 20 30 40 50 60
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
430 440 450 460 470
>>NP_001138881 (OMIM: 300084,300967) non-POU domain-cont (471 aa)
initn: 3200 init1: 3200 opt: 3200 Z-score: 1619.4 bits: 309.0 E(85289): 1.8e-83
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)
10 20 30 40 50 60
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
430 440 450 460 470
>>NP_001138882 (OMIM: 300084,300967) non-POU domain-cont (382 aa)
initn: 2567 init1: 2567 opt: 2567 Z-score: 1304.6 bits: 250.4 E(85289): 6.3e-66
Smith-Waterman score: 2567; 100.0% identity (100.0% similar) in 382 aa overlap (90-471:1-382)
60 70 80 90 100 110
pF1KB5 KNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETR
::::::::::::::::::::::::::::::
NP_001 MRKLFEKYGKAGEVFIHKDKGFGFIRLETR
10 20 30
120 130 140 150 160 170
pF1KB5 TLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVV
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB5 IVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEK
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB5 LVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEME
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB5 MEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQ
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB5 EEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATM
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB5 MPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
340 350 360 370 380
>>XP_011533439 (OMIM: 612408) PREDICTED: paraspeckle com (469 aa)
initn: 1679 init1: 1594 opt: 1776 Z-score: 909.3 bits: 177.6 E(85289): 6.6e-44
Smith-Waterman score: 1776; 63.8% identity (84.0% similar) in 425 aa overlap (37-460:45-463)
10 20 30 40 50 60
pF1KB5 FNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPG
: :: :: .. ... :.:::.:.: :::
XP_011 NPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPG
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB5 EKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAK
:::.::: :::::::: :::::....:::.::. .::::..:.::::::::.::::::::
XP_011 EKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAK
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB5 VELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGR
.:::. :... ::.::: :.:.:::.:: :::::::.::: :: ::.:::.::::::
XP_011 AELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGR
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB5 PSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQ
.:::.:::..:: :::::.::..:.::::: :::: ::::.:.:::.::::::. :.::
XP_011 ATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQ
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB5 FHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE
.::::::::::::::.::.::: ::::: ::::::..::::::.::.:::: ::::::::
XP_011 YHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHE
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB5 HQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM-RRQQEEMMRR
::.::::::::::::::::.:::.:::.:::::..::.:::.::::::: :....: .::
XP_011 HQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRR
320 330 340 350 360 370
370 380 390 400 410 420
pF1KB5 QQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMMPDGTL
:::::: .. . ::::.:::.:. ::..... :. ::: ::. .:: : : ..
XP_011 QQEGFKPNYMENREQEMRMGDMGPRGAINMGD--AFSPAP--AGNQGPP-PMMGMNMNNR
380 390 400 410 420
430 440 450 460 470
pF1KB5 GLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY
. : : : :: . .: :: . .: :
XP_011 ATIPGPPMGPGPAMGPEGAANMG-TPMMPDNGAVGDKRKCG
430 440 450 460
>>XP_006719907 (OMIM: 612408) PREDICTED: paraspeckle com (523 aa)
initn: 1767 init1: 1594 opt: 1773 Z-score: 907.4 bits: 177.4 E(85289): 8.4e-44
Smith-Waterman score: 1780; 60.0% identity (79.1% similar) in 468 aa overlap (37-460:45-511)
10 20 30 40 50 60
pF1KB5 FNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPG
: :: :: .. ... :.:::.:.: :::
XP_006 NPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPG
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB5 EKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAK
:::.::: :::::::: :::::....:::.::. .::::..:.::::::::.::::::::
XP_006 EKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAK
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB5 VELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGR
.:::. :... ::.::: :.:.:::.:: :::::::.::: :: ::.:::.::::::
XP_006 AELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGR
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB5 PSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQ
.:::.:::..:: :::::.::..:.::::: :::: ::::.:.:::.::::::. :.::
XP_006 ATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQ
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB5 FHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE
.::::::::::::::.::.::: ::::: ::::::..::::::.::.:::: ::::::::
XP_006 YHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHE
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB5 HQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM-RRQQEEMMRR
::.::::::::::::::::.:::.:::.:::::..::.:::.::::::: :....: .::
XP_006 HQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRR
320 330 340 350 360 370
370 380 390 400
pF1KB5 QQEGFKGTFPDAREQEIRMGQMA------MGGA----------------MGINNRGAMPP
:::::: .. . ::::.:::.:. :: : :..:::...:
XP_006 QQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNMNNRATIPG
380 390 400 410 420 430
410 420 430 440
pF1KB5 APVPAGTPA--PPGPATM----MPDG------TLGLTPPTT------ERFGQA---ATME
:. : :: : : :.: :::. . ::. : :. : :
XP_006 PPMGPG-PAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMGSRTGSETPQAPMS
440 450 460 470 480 490
450 460 470
pF1KB5 GIGAIGGTPPAFNRAAPGAEFAPNKRRRY
:.: ..: : .:.:.. :
XP_006 GVGPVSGGPGGFGRGSQGGNFEGPNKRRRY
500 510 520
>>NP_001035879 (OMIM: 612408) paraspeckle component 1 [H (523 aa)
initn: 1767 init1: 1594 opt: 1773 Z-score: 907.4 bits: 177.4 E(85289): 8.4e-44
Smith-Waterman score: 1780; 60.0% identity (79.1% similar) in 468 aa overlap (37-460:45-511)
10 20 30 40 50 60
pF1KB5 FNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPG
: :: :: .. ... :.:::.:.: :::
NP_001 NPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPG
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB5 EKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAK
:::.::: :::::::: :::::....:::.::. .::::..:.::::::::.::::::::
NP_001 EKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAK
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB5 VELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGR
.:::. :... ::.::: :.:.:::.:: :::::::.::: :: ::.:::.::::::
NP_001 AELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGR
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB5 PSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQ
.:::.:::..:: :::::.::..:.::::: :::: ::::.:.:::.::::::. :.::
NP_001 ATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQ
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB5 FHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE
.::::::::::::::.::.::: ::::: ::::::..::::::.::.:::: ::::::::
NP_001 YHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHE
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB5 HQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM-RRQQEEMMRR
::.::::::::::::::::.:::.:::.:::::..::.:::.::::::: :....: .::
NP_001 HQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRR
320 330 340 350 360 370
370 380 390 400
pF1KB5 QQEGFKGTFPDAREQEIRMGQMA------MGGA----------------MGINNRGAMPP
:::::: .. . ::::.:::.:. :: : :..:::...:
NP_001 QQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNMNNRATIPG
380 390 400 410 420 430
410 420 430 440
pF1KB5 APVPAGTPA--PPGPATM----MPDG------TLGLTPPTT------ERFGQA---ATME
:. : :: : : :.: :::. . ::. : :. : :
NP_001 PPMGPG-PAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMGSRTGSETPQAPMS
440 450 460 470 480 490
450 460 470
pF1KB5 GIGAIGGTPPAFNRAAPGAEFAPNKRRRY
:.: ..: : .:.:.. :
NP_001 GVGPVSGGPGGFGRGSQGGNFEGPNKRRRY
500 510 520
>>XP_016857543 (OMIM: 605199) PREDICTED: splicing factor (707 aa)
initn: 1765 init1: 1622 opt: 1716 Z-score: 877.7 bits: 172.3 E(85289): 3.8e-42
Smith-Waterman score: 1778; 60.0% identity (79.9% similar) in 473 aa overlap (16-471:241-707)
10 20 30 40
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANG
:: .::: .:::..: ::: . .
XP_016 KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH--PPYHQQHHQGPPPGGPGGRS
220 230 240 250 260
50 60 70 80 90 100
pF1KB5 QQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI
.. :..::. .:. .:.:::::.::: :::::::: ::::.:...:: :::. :::::
XP_016 EEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI
270 280 290 300 310 320
110 120 130 140 150 160
pF1KB5 HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLE
.: ::::::.::.:.::::::.:::. :.::.::::::: :.:.:.:::: ::::::::
XP_016 NKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLE
330 340 350 360 370 380
170 180 190 200 210 220
pF1KB5 EAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVE
:::: :: .:::::::::::: .:::::::..:::::::..::::: ::::: :::: ::
XP_016 EAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVE
390 400 410 420 430 440
230 240 250 260 270 280
pF1KB5 PMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV
:..:::::.::::::. :: ...:::: :::::: :.:::::..:::.: ::::::..::
XP_016 PLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQV
450 460 470 480 490 500
290 300 310 320 330 340
pF1KB5 DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE
..:.:.:..::: ::: : ::::. :.:::::::::::::::::::::.::::...::::
XP_016 EKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQE
510 520 530 540 550 560
350 360 370 380 390
pF1KB5 EERRRREEEM---RRQQEEMMRRQ-QEGF-KGTFPDAREQEIRMG---QMAMGGAMGINN
:::::::::: .:..::.:::: .:.. . . : ::...::: : :: .: ..
XP_016 EERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAMNMGDPYGSGG
570 580 590 600 610 620
400 410 420 430 440
pF1KB5 RGAMPPAPVPAGT--PAPPG--PATMMPDGTLGLTPPTTERFGQ--AATMEGIGAIG---
. .:: .: : :: :::: .:.. . :::::: :. . : : :
XP_016 Q-KFPPLGGGGGIGYEANPGVPPATM--SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGP
630 640 650 660 670 680
450 460 470
pF1KB5 GTPPAFNRAAPGAEFAPNKRRRY
::: ...:. : .:::. :.
XP_016 GTPAGYGRGREEYE-GPNKKPRF
690 700
>>XP_005271170 (OMIM: 605199) PREDICTED: splicing factor (707 aa)
initn: 1765 init1: 1622 opt: 1716 Z-score: 877.7 bits: 172.3 E(85289): 3.8e-42
Smith-Waterman score: 1778; 60.0% identity (79.9% similar) in 473 aa overlap (16-471:241-707)
10 20 30 40
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANG
:: .::: .:::..: ::: . .
XP_005 KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH--PPYHQQHHQGPPPGGPGGRS
220 230 240 250 260
50 60 70 80 90 100
pF1KB5 QQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI
.. :..::. .:. .:.:::::.::: :::::::: ::::.:...:: :::. :::::
XP_005 EEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI
270 280 290 300 310 320
110 120 130 140 150 160
pF1KB5 HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLE
.: ::::::.::.:.::::::.:::. :.::.::::::: :.:.:.:::: ::::::::
XP_005 NKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLE
330 340 350 360 370 380
170 180 190 200 210 220
pF1KB5 EAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVE
:::: :: .:::::::::::: .:::::::..:::::::..::::: ::::: :::: ::
XP_005 EAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVE
390 400 410 420 430 440
230 240 250 260 270 280
pF1KB5 PMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV
:..:::::.::::::. :: ...:::: :::::: :.:::::..:::.: ::::::..::
XP_005 PLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQV
450 460 470 480 490 500
290 300 310 320 330 340
pF1KB5 DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE
..:.:.:..::: ::: : ::::. :.:::::::::::::::::::::.::::...::::
XP_005 EKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQE
510 520 530 540 550 560
350 360 370 380 390
pF1KB5 EERRRREEEM---RRQQEEMMRRQ-QEGF-KGTFPDAREQEIRMG---QMAMGGAMGINN
:::::::::: .:..::.:::: .:.. . . : ::...::: : :: .: ..
XP_005 EERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAMNMGDPYGSGG
570 580 590 600 610 620
400 410 420 430 440
pF1KB5 RGAMPPAPVPAGT--PAPPG--PATMMPDGTLGLTPPTTERFGQ--AATMEGIGAIG---
. .:: .: : :: :::: .:.. . :::::: :. . : : :
XP_005 Q-KFPPLGGGGGIGYEANPGVPPATM--SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGP
630 640 650 660 670 680
450 460 470
pF1KB5 GTPPAFNRAAPGAEFAPNKRRRY
::: ...:. : .:::. :.
XP_005 GTPAGYGRGREEYE-GPNKKPRF
690 700
>>XP_005271169 (OMIM: 605199) PREDICTED: splicing factor (707 aa)
initn: 1765 init1: 1622 opt: 1716 Z-score: 877.7 bits: 172.3 E(85289): 3.8e-42
Smith-Waterman score: 1778; 60.0% identity (79.9% similar) in 473 aa overlap (16-471:241-707)
10 20 30 40
pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANG
:: .::: .:::..: ::: . .
XP_005 KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH--PPYHQQHHQGPPPGGPGGRS
220 230 240 250 260
50 60 70 80 90 100
pF1KB5 QQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI
.. :..::. .:. .:.:::::.::: :::::::: ::::.:...:: :::. :::::
XP_005 EEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI
270 280 290 300 310 320
110 120 130 140 150 160
pF1KB5 HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLE
.: ::::::.::.:.::::::.:::. :.::.::::::: :.:.:.:::: ::::::::
XP_005 NKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLE
330 340 350 360 370 380
170 180 190 200 210 220
pF1KB5 EAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVE
:::: :: .:::::::::::: .:::::::..:::::::..::::: ::::: :::: ::
XP_005 EAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVE
390 400 410 420 430 440
230 240 250 260 270 280
pF1KB5 PMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV
:..:::::.::::::. :: ...:::: :::::: :.:::::..:::.: ::::::..::
XP_005 PLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQV
450 460 470 480 490 500
290 300 310 320 330 340
pF1KB5 DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE
..:.:.:..::: ::: : ::::. :.:::::::::::::::::::::.::::...::::
XP_005 EKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQE
510 520 530 540 550 560
350 360 370 380 390
pF1KB5 EERRRREEEM---RRQQEEMMRRQ-QEGF-KGTFPDAREQEIRMG---QMAMGGAMGINN
:::::::::: .:..::.:::: .:.. . . : ::...::: : :: .: ..
XP_005 EERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAMNMGDPYGSGG
570 580 590 600 610 620
400 410 420 430 440
pF1KB5 RGAMPPAPVPAGT--PAPPG--PATMMPDGTLGLTPPTTERFGQ--AATMEGIGAIG---
. .:: .: : :: :::: .:.. . :::::: :. . : : :
XP_005 Q-KFPPLGGGGGIGYEANPGVPPATM--SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGP
630 640 650 660 670 680
450 460 470
pF1KB5 GTPPAFNRAAPGAEFAPNKRRRY
::: ...:. : .:::. :.
XP_005 GTPAGYGRGREEYE-GPNKKPRF
690 700
471 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:42:58 2016 done: Fri Nov 4 03:43:00 2016
Total Scan time: 11.070 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]