Result of FASTA (omim) for
pFN21AB5275
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5275, 469 aa
1>>>pF1KB5275 469 - 469 aa - 469 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2734+/-0.000314; mu= 18.3832+/- 0.020
mean_var=72.2655+/-14.439, 0's: 0 Z-trim(116.1): 14 B-trim: 33 in 1/51
Lambda= 0.150872
statistics sampled from 27001 (27015) to 27001 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.317), width: 16
Scan time: 7.560
The best scores are: opt bits E(85289)
NP_001243808 (OMIM: 600815) DNA polymerase delta s ( 469) 3145 693.7 2.8e-199
NP_001120690 (OMIM: 600815) DNA polymerase delta s ( 469) 3145 693.7 2.8e-199
XP_011513733 (OMIM: 600815) PREDICTED: DNA polymer ( 502) 3145 693.7 2.9e-199
NP_006221 (OMIM: 600815) DNA polymerase delta subu ( 504) 3145 693.7 2.9e-199
>>NP_001243808 (OMIM: 600815) DNA polymerase delta subun (469 aa)
initn: 3145 init1: 3145 opt: 3145 Z-score: 3698.8 bits: 693.7 E(85289): 2.8e-199
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KB5 MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
370 380 390 400 410 420
430 440 450 460
pF1KB5 QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
430 440 450 460
>>NP_001120690 (OMIM: 600815) DNA polymerase delta subun (469 aa)
initn: 3145 init1: 3145 opt: 3145 Z-score: 3698.8 bits: 693.7 E(85289): 2.8e-199
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KB5 MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
370 380 390 400 410 420
430 440 450 460
pF1KB5 QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
430 440 450 460
>>XP_011513733 (OMIM: 600815) PREDICTED: DNA polymerase (502 aa)
initn: 3145 init1: 3145 opt: 3145 Z-score: 3698.4 bits: 693.7 E(85289): 2.9e-199
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:34-502)
10 20 30
pF1KB5 MFSEQAAQRAHTLLSPPSANNATFARVPVA
::::::::::::::::::::::::::::::
XP_011 LVTDGARRAAIVNLLGLGEAVWTKQVRSVAMFSEQAAQRAHTLLSPPSANNATFARVPVA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 TYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 CCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 SKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 SLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 ASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTN
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 PYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPI
430 440 450 460 470 480
460
pF1KB5 SFSGFGAEDDDLGGLGLGP
:::::::::::::::::::
XP_011 SFSGFGAEDDDLGGLGLGP
490 500
>>NP_006221 (OMIM: 600815) DNA polymerase delta subunit (504 aa)
initn: 3145 init1: 3145 opt: 3145 Z-score: 3698.3 bits: 693.7 E(85289): 2.9e-199
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:36-504)
10 20 30
pF1KB5 MFSEQAAQRAHTLLSPPSANNATFARVPVA
::::::::::::::::::::::::::::::
NP_006 ARGLAGCGAPRVNLLGLGEAVWTKQVRSVAMFSEQAAQRAHTLLSPPSANNATFARVPVA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 TYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 CCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 SKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 SLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 ASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTN
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 PYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPI
430 440 450 460 470 480
460
pF1KB5 SFSGFGAEDDDLGGLGLGP
:::::::::::::::::::
NP_006 SFSGFGAEDDDLGGLGLGP
490 500
469 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:31:21 2016 done: Fri Nov 4 03:31:22 2016
Total Scan time: 7.560 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]