Result of FASTA (omim) for
pFN21AB4411
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4411, 186 aa
1>>>pF1KB4411 186 - 186 aa - 186 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5656+/-0.000386; mu= 17.6297+/- 0.024
mean_var=80.2420+/-16.252, 0's: 0 Z-trim(114.7): 367 B-trim: 632 in 1/53
Lambda= 0.143177
statistics sampled from 24206 (24653) to 24206 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.289), width: 16
Scan time: 5.740
The best scores are: opt bits E(85289)
XP_006724169 (OMIM: 615870,615996) PREDICTED: intr ( 186) 1232 263.6 1.3e-70
NP_001171172 (OMIM: 615870,615996) intraflagellar ( 186) 1232 263.6 1.3e-70
NP_006851 (OMIM: 615870,615996) intraflagellar tra ( 185) 1212 259.5 2.3e-69
XP_016884029 (OMIM: 615870,615996) PREDICTED: intr ( 145) 970 209.4 2.2e-54
NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201) 322 75.7 5.3e-14
NP_055303 (OMIM: 605693) ras-related protein Rab-3 ( 203) 321 75.5 6.1e-14
NP_001272988 (OMIM: 605693) ras-related protein Ra ( 203) 321 75.5 6.1e-14
NP_001272990 (OMIM: 605693) ras-related protein Ra ( 203) 321 75.5 6.1e-14
NP_001272989 (OMIM: 605693) ras-related protein Ra ( 203) 321 75.5 6.1e-14
NP_004152 (OMIM: 179508) ras-related protein Rab-1 ( 205) 321 75.5 6.1e-14
NP_112243 (OMIM: 612565) ras-related protein Rab-1 ( 201) 315 74.2 1.4e-13
NP_002861 (OMIM: 602672) ras-related protein Rab-1 ( 203) 311 73.4 2.6e-13
NP_002856 (OMIM: 179509) ras-related protein Rab-2 ( 212) 311 73.4 2.6e-13
NP_116235 (OMIM: 607466) ras-related protein Rab-2 ( 216) 305 72.2 6.3e-13
NP_005361 (OMIM: 165040) ras-related protein Rab-8 ( 207) 302 71.6 9.4e-13
NP_057215 (OMIM: 612672) ras-related protein Rab-1 ( 200) 301 71.3 1.1e-12
NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207) 301 71.4 1.1e-12
NP_004153 (OMIM: 179512) ras-related protein Rab-5 ( 215) 301 71.4 1.1e-12
NP_004785 (OMIM: 300333) ras-related protein Rab-3 ( 237) 299 71.0 1.6e-12
XP_011526322 (OMIM: 165040) PREDICTED: ras-related ( 215) 296 70.3 2.3e-12
NP_001006639 (OMIM: 609956) ras-related protein Ra ( 223) 296 70.4 2.3e-12
NP_001265595 (OMIM: 201000,606144) ras-related pro ( 237) 294 70.0 3.2e-12
NP_001265596 (OMIM: 201000,606144) ras-related pro ( 237) 294 70.0 3.2e-12
NP_899050 (OMIM: 201000,606144) ras-related protei ( 237) 294 70.0 3.2e-12
NP_057361 (OMIM: 201000,606144) ras-related protei ( 237) 294 70.0 3.2e-12
NP_001265597 (OMIM: 201000,606144) ras-related pro ( 237) 294 70.0 3.2e-12
NP_055168 (OMIM: 605455) ras-related protein Rab-2 ( 256) 294 70.0 3.4e-12
NP_001317400 (OMIM: 609956) ras-related protein Ra ( 196) 292 69.5 3.8e-12
NP_001157461 (OMIM: 609956) ras-related protein Ra ( 228) 292 69.5 4.2e-12
NP_001294982 (OMIM: 605455) ras-related protein Ra ( 190) 286 68.2 8.8e-12
XP_011523393 (OMIM: 604037) PREDICTED: ras-related ( 216) 285 68.1 1.1e-11
NP_958842 (OMIM: 604037) ras-related protein Rab-5 ( 216) 285 68.1 1.1e-11
XP_011523392 (OMIM: 604037) PREDICTED: ras-related ( 216) 285 68.1 1.1e-11
NP_004574 (OMIM: 604037) ras-related protein Rab-5 ( 216) 285 68.1 1.1e-11
NP_001238968 (OMIM: 604037) ras-related protein Ra ( 249) 285 68.1 1.2e-11
NP_783865 (OMIM: 609956) ras-related protein Rab-3 ( 216) 283 67.7 1.5e-11
NP_057661 (OMIM: 615852) ras-related protein Rab-6 ( 208) 282 67.4 1.7e-11
NP_004654 (OMIM: 605570) ras-related protein Rab-1 ( 216) 282 67.5 1.7e-11
NP_942599 (OMIM: 179513) ras-related protein Rab-6 ( 208) 280 67.0 2.2e-11
NP_741995 (OMIM: 300774) ras-related protein Rab-3 ( 213) 280 67.0 2.2e-11
XP_005269109 (OMIM: 179514) PREDICTED: ras-related ( 215) 279 66.8 2.6e-11
XP_005269108 (OMIM: 179514) PREDICTED: ras-related ( 215) 279 66.8 2.6e-11
NP_002859 (OMIM: 179514) ras-related protein Rab-5 ( 215) 279 66.8 2.6e-11
NP_001238965 (OMIM: 179514) ras-related protein Ra ( 215) 279 66.8 2.6e-11
XP_011511195 (OMIM: 615852) PREDICTED: ras-related ( 195) 273 65.5 5.7e-11
NP_002860 (OMIM: 179513) ras-related protein Rab-6 ( 208) 273 65.6 6e-11
NP_057406 (OMIM: 612673) ras-related protein Rab-1 ( 215) 272 65.4 7.1e-11
XP_011526466 (OMIM: 179490) PREDICTED: ras-related ( 220) 271 65.2 8.3e-11
NP_002857 (OMIM: 179490) ras-related protein Rab-3 ( 220) 271 65.2 8.3e-11
NP_006859 (OMIM: 605694) ras-related protein Rab-3 ( 195) 269 64.7 1e-10
>>XP_006724169 (OMIM: 615870,615996) PREDICTED: intrafla (186 aa)
initn: 1232 init1: 1232 opt: 1232 Z-score: 1388.7 bits: 263.6 E(85289): 1.3e-70
Smith-Waterman score: 1232; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)
10 20 30 40 50 60
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVE
130 140 150 160 170 180
pF1KB4 VFRALA
::::::
XP_006 VFRALA
>>NP_001171172 (OMIM: 615870,615996) intraflagellar tran (186 aa)
initn: 1232 init1: 1232 opt: 1232 Z-score: 1388.7 bits: 263.6 E(85289): 1.3e-70
Smith-Waterman score: 1232; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)
10 20 30 40 50 60
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVE
130 140 150 160 170 180
pF1KB4 VFRALA
::::::
NP_001 VFRALA
>>NP_006851 (OMIM: 615870,615996) intraflagellar transpo (185 aa)
initn: 1210 init1: 1157 opt: 1212 Z-score: 1366.4 bits: 259.5 E(85289): 2.3e-69
Smith-Waterman score: 1212; 99.5% identity (99.5% similar) in 186 aa overlap (1-186:1-185)
10 20 30 40 50 60
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVEL
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MVKLAAKCILA-DPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVEL
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 FIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 VGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVE
120 130 140 150 160 170
pF1KB4 VFRALA
::::::
NP_006 VFRALA
180
>>XP_016884029 (OMIM: 615870,615996) PREDICTED: intrafla (145 aa)
initn: 970 init1: 970 opt: 970 Z-score: 1097.5 bits: 209.4 E(85289): 2.2e-54
Smith-Waterman score: 970; 100.0% identity (100.0% similar) in 145 aa overlap (42-186:1-145)
20 30 40 50 60 70
pF1KB4 GDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKELF
::::::::::::::::::::::::::::::
XP_016 MDLVVKTVPVPDTGDSVELFIFDSAGKELF
10 20 30
80 90 100 110 120 130
pF1KB4 SEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAGRR
40 50 60 70 80 90
140 150 160 170 180
pF1KB4 AVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVEVFRALA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVEVFRALA
100 110 120 130 140
>>NP_006852 (OMIM: 604199) ras-related protein Rab-35 is (201 aa)
initn: 216 init1: 104 opt: 322 Z-score: 372.4 bits: 75.7 E(85289): 5.3e-14
Smith-Waterman score: 322; 35.0% identity (66.9% similar) in 163 aa overlap (7-169:10-166)
10 20 30 40 50
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDS
: .. :: .:::..: ..: :. :: : :.:. ..:: . .:..
NP_006 MARDYDHLFKLLIIGDSGVGKSSL--LLRFADNTFSGSYITTIGVDFKIRTVEI--NGEK
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 VELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLP
:.: :.:.::.: : . . ... . . .:::::. ::: : ..::.. .. .
NP_006 VKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVC--
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 GVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYRE
.:::::.: :..:.. .: .: .:.. ::::.:: : : :.:...
NP_006 RILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKD
120 130 140 150 160 170
180
pF1KB4 KVEVFRALA
NP_006 NLAKQQQQQQNDVVKLTKNSKRKKRCC
180 190 200
>>NP_055303 (OMIM: 605693) ras-related protein Rab-30 [H (203 aa)
initn: 238 init1: 121 opt: 321 Z-score: 371.3 bits: 75.5 E(85289): 6.1e-14
Smith-Waterman score: 321; 37.7% identity (68.0% similar) in 175 aa overlap (7-181:11-180)
10 20 30 40 50
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGD
: .: :. .:::: :.. : ..: : . : :.:...::: . .:.
NP_055 MSMEDYDFLFKIVLIGNAGVGKTCLVRRF-TQGL-FPPGQGATIGVDFMIKTVEI--NGE
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 SVELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISL
.:.: :.:.::.: : . .. ..: :.: :.::.: :::: .::.. .. : . ..
NP_055 KVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASN-KV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 PGVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYR
:::::: ::: :: :.. .:. .. .: . .:::.:: .: : : :: .. . :
NP_055 ITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEAR
120 130 140 150 160 170
180
pF1KB4 EKVEVFRALA
... :
NP_055 QNTLVNNVSSPLPGEGKSISYLTCCNFN
180 190 200
>>NP_001272988 (OMIM: 605693) ras-related protein Rab-30 (203 aa)
initn: 238 init1: 121 opt: 321 Z-score: 371.3 bits: 75.5 E(85289): 6.1e-14
Smith-Waterman score: 321; 37.7% identity (68.0% similar) in 175 aa overlap (7-181:11-180)
10 20 30 40 50
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGD
: .: :. .:::: :.. : ..: : . : :.:...::: . .:.
NP_001 MSMEDYDFLFKIVLIGNAGVGKTCLVRRF-TQGL-FPPGQGATIGVDFMIKTVEI--NGE
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 SVELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISL
.:.: :.:.::.: : . .. ..: :.: :.::.: :::: .::.. .. : . ..
NP_001 KVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASN-KV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 PGVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYR
:::::: ::: :: :.. .:. .. .: . .:::.:: .: : : :: .. . :
NP_001 ITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEAR
120 130 140 150 160 170
180
pF1KB4 EKVEVFRALA
... :
NP_001 QNTLVNNVSSPLPGEGKSISYLTCCNFN
180 190 200
>>NP_001272990 (OMIM: 605693) ras-related protein Rab-30 (203 aa)
initn: 238 init1: 121 opt: 321 Z-score: 371.3 bits: 75.5 E(85289): 6.1e-14
Smith-Waterman score: 321; 37.7% identity (68.0% similar) in 175 aa overlap (7-181:11-180)
10 20 30 40 50
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGD
: .: :. .:::: :.. : ..: : . : :.:...::: . .:.
NP_001 MSMEDYDFLFKIVLIGNAGVGKTCLVRRF-TQGL-FPPGQGATIGVDFMIKTVEI--NGE
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 SVELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISL
.:.: :.:.::.: : . .. ..: :.: :.::.: :::: .::.. .. : . ..
NP_001 KVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASN-KV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 PGVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYR
:::::: ::: :: :.. .:. .. .: . .:::.:: .: : : :: .. . :
NP_001 ITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEAR
120 130 140 150 160 170
180
pF1KB4 EKVEVFRALA
... :
NP_001 QNTLVNNVSSPLPGEGKSISYLTCCNFN
180 190 200
>>NP_001272989 (OMIM: 605693) ras-related protein Rab-30 (203 aa)
initn: 238 init1: 121 opt: 321 Z-score: 371.3 bits: 75.5 E(85289): 6.1e-14
Smith-Waterman score: 321; 37.7% identity (68.0% similar) in 175 aa overlap (7-181:11-180)
10 20 30 40 50
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGD
: .: :. .:::: :.. : ..: : . : :.:...::: . .:.
NP_001 MSMEDYDFLFKIVLIGNAGVGKTCLVRRF-TQGL-FPPGQGATIGVDFMIKTVEI--NGE
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 SVELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISL
.:.: :.:.::.: : . .. ..: :.: :.::.: :::: .::.. .. : . ..
NP_001 KVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASN-KV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 PGVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYR
:::::: ::: :: :.. .:. .. .: . .:::.:: .: : : :: .. . :
NP_001 ITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEAR
120 130 140 150 160 170
180
pF1KB4 EKVEVFRALA
... :
NP_001 QNTLVNNVSSPLPGEGKSISYLTCCNFN
180 190 200
>>NP_004152 (OMIM: 179508) ras-related protein Rab-1A is (205 aa)
initn: 264 init1: 119 opt: 321 Z-score: 371.2 bits: 75.5 E(85289): 6.1e-14
Smith-Waterman score: 321; 34.1% identity (66.5% similar) in 167 aa overlap (7-173:13-174)
10 20 30 40 50
pF1KB4 MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDT
: .: :: .:::. : : .: . .:: : :.:. ..:. .
NP_004 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDT--YTESYISTIGVDFKIRTIELD--
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 GDSVELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGI
: ...: :.:.::.: : . .. ... . . .:::::..::::: ..::.. : .
NP_004 GKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYA-SE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 SLPGVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQL
.. .::::: ::. ...:: . :. .: . :. .:::.:. : : : .: ....
NP_004 NVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKR
120 130 140 150 160 170
180
pF1KB4 YREKVEVFRALA
NP_004 MGPGATAGGAEKSNVKIQSTPVKQSGGGCC
180 190 200
186 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:00:15 2016 done: Fri Nov 4 03:00:16 2016
Total Scan time: 5.740 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]