Result of FASTA (omim) for
pFN21AB3955
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3955, 454 aa
1>>>pF1KB3955 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6049+/-0.000389; mu= -6.9197+/- 0.024
mean_var=291.7638+/-60.998, 0's: 0 Z-trim(121.1): 143 B-trim: 0 in 0/55
Lambda= 0.075086
statistics sampled from 37166 (37309) to 37166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.437), width: 16
Scan time: 10.500
The best scores are: opt bits E(85289)
NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 3248 365.2 2e-100
XP_011513470 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1905 219.8 1.3e-56
XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1905 219.8 1.3e-56
NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 1905 219.8 1.3e-56
XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1905 219.8 1.3e-56
XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 1798 208.2 3.9e-53
XP_011513469 (OMIM: 600541) PREDICTED: ETS translo ( 491) 1797 208.1 4.4e-53
NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 1492 175.0 3.5e-43
NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 1443 169.7 1.2e-41
NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 1371 161.9 3e-39
NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 1365 161.3 5e-39
NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 1365 161.3 5e-39
NP_004445 (OMIM: 601600) ETS translocation variant ( 510) 1139 136.8 1.3e-31
NP_001248366 (OMIM: 600711) ETS translocation vari ( 445) 1084 130.8 7.2e-30
NP_001248367 (OMIM: 600711) ETS translocation vari ( 445) 1084 130.8 7.2e-30
NP_001073143 (OMIM: 600711) ETS translocation vari ( 484) 1084 130.8 7.7e-30
NP_001977 (OMIM: 600711) ETS translocation variant ( 484) 1084 130.8 7.7e-30
XP_016879838 (OMIM: 600711) PREDICTED: ETS translo ( 479) 1068 129.1 2.5e-29
NP_001248368 (OMIM: 600711) ETS translocation vari ( 207) 1007 122.3 1.3e-27
XP_011522816 (OMIM: 600711) PREDICTED: ETS translo ( 221) 1007 122.3 1.3e-27
NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 441 61.1 5.6e-09
XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 441 61.1 6.1e-09
XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 441 61.2 6.5e-09
NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 434 60.2 6.5e-09
XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 430 60.0 1.4e-08
NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 430 60.0 1.5e-08
XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 430 60.0 1.5e-08
XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 430 60.0 1.6e-08
XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 430 60.0 1.6e-08
NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 430 60.0 1.6e-08
XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 429 59.9 1.7e-08
NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 429 59.9 1.7e-08
XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 429 59.9 1.7e-08
XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 430 60.0 1.7e-08
NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 429 60.0 2.1e-08
NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 405 57.2 8.9e-08
XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 405 57.3 1e-07
NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 405 57.3 1.1e-07
NP_001230357 (OMIM: 165080) transcriptional regula ( 486) 405 57.3 1.1e-07
NP_001129626 (OMIM: 165080) transcriptional regula ( 486) 405 57.3 1.1e-07
NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 393 55.9 2.1e-07
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 393 56.0 2.4e-07
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 393 56.0 2.4e-07
NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 393 56.0 2.5e-07
NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 393 56.0 2.5e-07
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 384 54.8 3.1e-07
NP_001244097 (OMIM: 311040) ETS domain-containing ( 95) 373 53.3 3.2e-07
NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 382 54.6 3.4e-07
XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410) 386 55.2 3.9e-07
NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 384 54.9 4.3e-07
>>NP_001156619 (OMIM: 600541) ETS translocation variant (454 aa)
initn: 3248 init1: 3248 opt: 3248 Z-score: 1924.0 bits: 365.2 E(85289): 2e-100
Smith-Waterman score: 3248; 99.8% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDSGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVGSAASQSFPPPLMIKQEPRDFAYDSGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 REGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 MNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHIN
370 380 390 400 410 420
430 440 450
pF1KB3 EEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
::::::::::::::::::::::::::::::::::
NP_001 EEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
430 440 450
>>XP_011513470 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 3234 init1: 1905 opt: 1905 Z-score: 1137.5 bits: 219.8 E(85289): 1.3e-56
Smith-Waterman score: 3192; 95.0% identity (95.2% similar) in 477 aa overlap (1-454:1-477)
10 20 30 40 50 60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
190 200 210 220 230 240
250 260 270
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPRQ
::::::::::::::::::::::::::: ::::::::::
XP_011 MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
430 440 450 460 470
>>XP_005249693 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 3234 init1: 1905 opt: 1905 Z-score: 1137.5 bits: 219.8 E(85289): 1.3e-56
Smith-Waterman score: 3192; 95.0% identity (95.2% similar) in 477 aa overlap (1-454:1-477)
10 20 30 40 50 60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_005 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
190 200 210 220 230 240
250 260 270
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPRQ
::::::::::::::::::::::::::: ::::::::::
XP_005 MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
430 440 450 460 470
>>NP_004947 (OMIM: 600541) ETS translocation variant 1 i (477 aa)
initn: 3234 init1: 1905 opt: 1905 Z-score: 1137.5 bits: 219.8 E(85289): 1.3e-56
Smith-Waterman score: 3192; 95.0% identity (95.2% similar) in 477 aa overlap (1-454:1-477)
10 20 30 40 50 60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_004 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
190 200 210 220 230 240
250 260 270
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPRQ
::::::::::::::::::::::::::: ::::::::::
NP_004 MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
430 440 450 460 470
>>XP_005249692 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 3234 init1: 1905 opt: 1905 Z-score: 1137.5 bits: 219.8 E(85289): 1.3e-56
Smith-Waterman score: 3192; 95.0% identity (95.2% similar) in 477 aa overlap (1-454:1-477)
10 20 30 40 50 60
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLYN
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_005 AQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNT
190 200 210 220 230 240
250 260 270
pF1KB3 MVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPRQ
::::::::::::::::::::::::::: ::::::::::
XP_005 MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
430 440 450 460 470
>>XP_011513472 (OMIM: 600541) PREDICTED: ETS translocati (472 aa)
initn: 3126 init1: 1797 opt: 1798 Z-score: 1074.9 bits: 208.2 E(85289): 3.9e-53
Smith-Waterman score: 3085; 93.4% identity (94.5% similar) in 470 aa overlap (9-454:3-472)
10 20 30 40 50
pF1KB3 MDGFYDQQVPYM-VTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLA
.:. . .::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLPFSDLDKSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLA
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 EAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQEQPFKFSYGEKCLY
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 EAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 NVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 YPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHN
180 190 200 210 220 230
240 250 260 270
pF1KB3 TMVGSAASQSFPPPLMIKQEPRDFAYDS-----------------------GCMFEKGPR
:::::::::::::::::::::::::::: :::::::::
XP_011 TMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPR
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB3 QFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGR
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB3 GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPE
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB3 ALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
420 430 440 450 460 470
>>XP_011513469 (OMIM: 600541) PREDICTED: ETS translocati (491 aa)
initn: 3126 init1: 1797 opt: 1797 Z-score: 1074.1 bits: 208.1 E(85289): 4.4e-53
Smith-Waterman score: 3084; 94.8% identity (95.0% similar) in 462 aa overlap (16-454:30-491)
10 20 30 40
pF1KB3 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEEL
:::::::::::::::::::::::::::::::
XP_011 MSGRGDGGQQQLLHSKFLAGFVCHIEKNESQRGRNCNEKPTNVRKRKFINRDLAHDSEEL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 FQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEIGSACSQE
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_011 FQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB3 QPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 AHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQG
190 200 210 220 230 240
230 240 250 260
pF1KB3 FKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDS-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_011 FKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB3 ----GCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLD
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB3 DPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVA
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB3 GERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCC
430 440 450 460 470 480
450
pF1KB3 NPHPYNEGYVY
:::::::::::
XP_011 NPHPYNEGYVY
490
>>NP_001156622 (OMIM: 600541) ETS translocation variant (437 aa)
initn: 2821 init1: 1492 opt: 1492 Z-score: 896.2 bits: 175.0 E(85289): 3.5e-43
Smith-Waterman score: 2779; 94.2% identity (94.5% similar) in 417 aa overlap (61-454:21-437)
40 50 60 70 80 90
pF1KB3 KRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKK
::::::::::::::::::::::::::::::
NP_001 MLQDLSASVFFPPCSQHRTLAQVPDNDEQFVPDYQAESLAFHGLPLKIKK
10 20 30 40 50
100 110 120 130 140 150
pF1KB3 EPHSPCSEIGSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHH
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHH
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB3 ASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPM
120 130 140 150 160 170
220 230 240 250 260
pF1KB3 YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDS---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVP
180 190 200 210 220 230
270 280 290 300
pF1KB3 --------------------GCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQ
::::::::::::::::::::::::::::::::::::::::
NP_001 SCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 RSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
360 370 380 390 400 410
430 440 450
pF1KB3 SHFDESMAYMPEGGCCNPHPYNEGYVY
:::::::::::::::::::::::::::
NP_001 SHFDESMAYMPEGGCCNPHPYNEGYVY
420 430
>>NP_001156624 (OMIM: 600541) ETS translocation variant (374 aa)
initn: 2348 init1: 1343 opt: 1443 Z-score: 868.5 bits: 169.7 E(85289): 1.2e-41
Smith-Waterman score: 2184; 79.1% identity (79.4% similar) in 417 aa overlap (61-454:21-374)
40 50 60 70 80 90
pF1KB3 KRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKK
::::::::::::::::::::::::::::::
NP_001 MLQDLSASVFFPPCSQHRTLAQVPDNDEQFVPDYQAESLAFHGLPLKIKK
10 20 30 40 50
100 110 120 130 140 150
pF1KB3 EPHSPCSEIGSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHH
:::::::::.:::::::::::::::::::::
NP_001 EPHSPCSEISSACSQEQPFKFSYGEKCLYNV-----------------------------
60 70 80
160 170 180 190 200 210
pF1KB3 ASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPM
::::::::::::::::::::::::::
NP_001 ----------------------------------RFRRQLSEPCNSFPPLPTMPREGRPM
90 100
220 230 240 250 260
pF1KB3 YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDS---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVP
110 120 130 140 150 160
270 280 290 300
pF1KB3 --------------------GCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQ
::::::::::::::::::::::::::::::::::::::::
NP_001 SCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQ
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB3 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLS
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB3 RSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPL
290 300 310 320 330 340
430 440 450
pF1KB3 SHFDESMAYMPEGGCCNPHPYNEGYVY
:::::::::::::::::::::::::::
NP_001 SHFDESMAYMPEGGCCNPHPYNEGYVY
350 360 370
>>NP_001156623 (OMIM: 600541) ETS translocation variant (419 aa)
initn: 2692 init1: 1363 opt: 1371 Z-score: 825.7 bits: 161.9 E(85289): 3e-39
Smith-Waterman score: 2658; 92.4% identity (93.2% similar) in 409 aa overlap (70-454:11-419)
40 50 60 70 80 90
pF1KB3 AHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESL-AFHGLPLKIKKEPHSPCSE
: : : ..: :::::::::::::::::::
NP_001 MLQDLSASVFFPPCSQHRTLVAFHGLPLKIKKEPHSPCSE
10 20 30 40
100 110 120 130 140 150
pF1KB3 IGSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHT
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHT
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB3 PKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEP
110 120 130 140 150 160
220 230 240 250 260
pF1KB3 NIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDS-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMR
170 180 190 200 210 220
270 280 290 300 310
pF1KB3 ------------GCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLW
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLW
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB3 QFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYE
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB3 KGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMA
350 360 370 380 390 400
440 450
pF1KB3 YMPEGGCCNPHPYNEGYVY
:::::::::::::::::::
NP_001 YMPEGGCCNPHPYNEGYVY
410
454 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:45:24 2016 done: Fri Nov 4 02:45:26 2016
Total Scan time: 10.500 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]