Result of FASTA (omim) for
pFN21AA0767
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0767, 578 aa
1>>>pF1KA0767 578 - 578 aa - 578 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4624+/-0.000444; mu= 9.5691+/- 0.027
mean_var=167.6084+/-33.289, 0's: 0 Z-trim(116.6): 37 B-trim: 746 in 1/55
Lambda= 0.099066
statistics sampled from 27806 (27843) to 27806 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.326), width: 16
Scan time: 9.530
The best scores are: opt bits E(85289)
XP_016884159 (OMIM: 613691) PREDICTED: GRAM domain ( 578) 3826 559.5 1.1e-158
XP_006724233 (OMIM: 613691) PREDICTED: GRAM domain ( 578) 3826 559.5 1.1e-158
NP_055939 (OMIM: 613691) GRAM domain-containing pr ( 578) 3826 559.5 1.1e-158
XP_006724232 (OMIM: 613691) PREDICTED: GRAM domain ( 601) 3826 559.5 1.1e-158
XP_005261453 (OMIM: 613691) PREDICTED: GRAM domain ( 604) 3826 559.5 1.1e-158
XP_011528313 (OMIM: 613691) PREDICTED: GRAM domain ( 577) 3623 530.5 5.9e-150
XP_011528314 (OMIM: 613691) PREDICTED: GRAM domain ( 555) 3473 509.0 1.6e-143
XP_011528315 (OMIM: 613691) PREDICTED: GRAM domain ( 561) 3470 508.6 2.2e-143
XP_011528316 (OMIM: 613691) PREDICTED: GRAM domain ( 453) 2761 407.2 6e-113
XP_005255017 (OMIM: 616297) PREDICTED: multiple C2 ( 466) 233 45.9 0.00036
XP_011520077 (OMIM: 616297) PREDICTED: multiple C2 ( 506) 233 45.9 0.00038
XP_016877892 (OMIM: 616297) PREDICTED: multiple C2 ( 866) 233 46.1 0.00057
XP_005255012 (OMIM: 616297) PREDICTED: multiple C2 ( 878) 233 46.1 0.00057
XP_006720666 (OMIM: 616297) PREDICTED: multiple C2 ( 878) 233 46.1 0.00057
NP_060819 (OMIM: 616297) multiple C2 and transmemb ( 878) 233 46.1 0.00057
XP_011520073 (OMIM: 616297) PREDICTED: multiple C2 ( 878) 233 46.1 0.00057
XP_011520074 (OMIM: 616297) PREDICTED: multiple C2 ( 878) 233 46.1 0.00057
>>XP_016884159 (OMIM: 613691) PREDICTED: GRAM domain-con (578 aa)
initn: 3826 init1: 3826 opt: 3826 Z-score: 2969.9 bits: 559.5 E(85289): 1.1e-158
Smith-Waterman score: 3826; 100.0% identity (100.0% similar) in 578 aa overlap (1-578:1-578)
10 20 30 40 50 60
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
490 500 510 520 530 540
550 560 570
pF1KA0 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
::::::::::::::::::::::::::::::::::::::
XP_016 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
550 560 570
>>XP_006724233 (OMIM: 613691) PREDICTED: GRAM domain-con (578 aa)
initn: 3826 init1: 3826 opt: 3826 Z-score: 2969.9 bits: 559.5 E(85289): 1.1e-158
Smith-Waterman score: 3826; 100.0% identity (100.0% similar) in 578 aa overlap (1-578:1-578)
10 20 30 40 50 60
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
490 500 510 520 530 540
550 560 570
pF1KA0 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
::::::::::::::::::::::::::::::::::::::
XP_006 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
550 560 570
>>NP_055939 (OMIM: 613691) GRAM domain-containing protei (578 aa)
initn: 3826 init1: 3826 opt: 3826 Z-score: 2969.9 bits: 559.5 E(85289): 1.1e-158
Smith-Waterman score: 3826; 100.0% identity (100.0% similar) in 578 aa overlap (1-578:1-578)
10 20 30 40 50 60
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
490 500 510 520 530 540
550 560 570
pF1KA0 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
::::::::::::::::::::::::::::::::::::::
NP_055 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
550 560 570
>>XP_006724232 (OMIM: 613691) PREDICTED: GRAM domain-con (601 aa)
initn: 3826 init1: 3826 opt: 3826 Z-score: 2969.7 bits: 559.5 E(85289): 1.1e-158
Smith-Waterman score: 3826; 100.0% identity (100.0% similar) in 578 aa overlap (1-578:24-601)
10 20 30
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIP
:::::::::::::::::::::::::::::::::::::
XP_006 MPVGLPREPERHVRVKQRTSVLNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 LKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 LRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAER
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 RSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 FVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 IVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 LYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 TDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENE
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 RPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDIT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 DIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGD
550 560 570 580 590 600
pF1KA0 S
:
XP_006 S
>>XP_005261453 (OMIM: 613691) PREDICTED: GRAM domain-con (604 aa)
initn: 3826 init1: 3826 opt: 3826 Z-score: 2969.7 bits: 559.5 E(85289): 1.1e-158
Smith-Waterman score: 3826; 100.0% identity (100.0% similar) in 578 aa overlap (1-578:27-604)
10 20 30
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSD
::::::::::::::::::::::::::::::::::
XP_005 MRVGPDIRSGEPERHVRVKQRTSVLNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 EIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 AERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 VTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 QWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 TQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 SLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLT
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 ENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 DITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILSQYIKITSAAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILSQYIKITSAAAS
550 560 570 580 590 600
pF1KA0 GGDS
::::
XP_005 GGDS
>>XP_011528313 (OMIM: 613691) PREDICTED: GRAM domain-con (577 aa)
initn: 3623 init1: 3623 opt: 3623 Z-score: 2813.2 bits: 530.5 E(85289): 5.9e-150
Smith-Waterman score: 3623; 100.0% identity (100.0% similar) in 545 aa overlap (1-545:1-545)
10 20 30 40 50 60
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
490 500 510 520 530 540
550 560 570
pF1KA0 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
:::::
XP_011 STQKPGQRNLSSHPKRFSQPCVPLSRGQKLVHHQSHS
550 560 570
>>XP_011528314 (OMIM: 613691) PREDICTED: GRAM domain-con (555 aa)
initn: 3470 init1: 3470 opt: 3473 Z-score: 2697.5 bits: 509.0 E(85289): 1.6e-143
Smith-Waterman score: 3627; 96.0% identity (96.0% similar) in 578 aa overlap (1-578:1-555)
10 20 30 40 50 60
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
:::::::::::::::::::::::::::::::::::::::::
XP_011 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQK-------------------
490 500 510 520
550 560 570
pF1KA0 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
::::::::::::::::::::::::::::::::::
XP_011 ----PLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
530 540 550
>>XP_011528315 (OMIM: 613691) PREDICTED: GRAM domain-con (561 aa)
initn: 3470 init1: 3470 opt: 3470 Z-score: 2695.1 bits: 508.6 E(85289): 2.2e-143
Smith-Waterman score: 3470; 100.0% identity (100.0% similar) in 521 aa overlap (1-521:27-547)
10 20 30
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSD
::::::::::::::::::::::::::::::::::
XP_011 MRVGPDIRSGEPERHVRVKQRTSVLNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 EIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 AERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 VTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 QWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 TQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 SLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLT
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 ENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 DITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILSQYIKITSAAAS
:::::::
XP_011 DITDIQKVNHHHRSVEAAGTK
550 560
>>XP_011528316 (OMIM: 613691) PREDICTED: GRAM domain-con (453 aa)
initn: 2747 init1: 2747 opt: 2761 Z-score: 2148.7 bits: 407.2 E(85289): 6e-113
Smith-Waterman score: 2761; 94.0% identity (96.4% similar) in 450 aa overlap (1-447:1-448)
10 20 30 40 50 60
pF1KA0 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
310 320 330 340 350 360
370 380 390 400 410
pF1KA0 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRR---LQTT
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRSQALQMC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 SSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRK
:. : :. : :... . . : : ..:..
XP_011 STASQ-PG-PRGMSRPRCSLRGGSDESGGLLGSPH
430 440 450
>>XP_005255017 (OMIM: 616297) PREDICTED: multiple C2 and (466 aa)
initn: 204 init1: 117 opt: 233 Z-score: 195.9 bits: 45.9 E(85289): 0.00036
Smith-Waterman score: 233; 29.5% identity (58.9% similar) in 190 aa overlap (183-363:226-413)
160 170 180 190 200 210
pF1KA0 NGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENT-VETEEPLSARRLTENMRRLKRG
: :.:. :: . :: . :.... :.::
XP_005 KNKDLEQAFKGVIYLEMDLIYNPVKASIRTFTPREKRFVEDSRKLSKKILSRDVDRVKRI
200 210 220 230 240 250
220 230 240 250 260
pF1KA0 AKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHG--WAIPLFLFLAILRLSLNYLIA
. . : .. :.. .: :. :.:::.:.. .::. . ::: :.: .. . . .
XP_005 TMAIWNTMQFLKSCFQWESTLRSTIAFAVFLITVWNFELYMIPLALLLIFVYNFIRPVKG
260 270 280 290 300 310
270 280 290 300 310 320
pF1KA0 RGWRIQWSIVPEVSEPVEPPKEDLTVSEK------FQLVLDVAQKAQNLFGKMADILEKI
. :: : : .. . :: ::: . .: :... .::.. ..:.. :.:
XP_005 KVSSIQDS--QESTDIDDEEDEDDKESEKKGLIERIYMVQDIVSTVQNVLEEIASFGERI
320 330 340 350 360 370
330 340 350 360 370 380
pF1KA0 KNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLR
:: : :. : ... . : :: . :.: : . : :.
XP_005 KNTFNWTVPFLSSLACLILAAATIILYFIPLRYIILIWGINKFTKKLRNPYSIDNNELLD
380 390 400 410 420 430
390 400 410 420 430 440
pF1KA0 AKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTK
XP_005 FLSRVPSDVQKVQYAELKLCSSHSPLRKKRSAL
440 450 460
578 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:59:15 2016 done: Fri Nov 4 00:59:16 2016
Total Scan time: 9.530 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]