Result of FASTA (omim) for
pFN21AA0600
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0600, 1037 aa
1>>>pF1KA0600 1037 - 1037 aa - 1037 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.9838+/-0.000407; mu= -7.9997+/- 0.025
mean_var=373.4691+/-77.991, 0's: 0 Z-trim(123.0): 187 B-trim: 1452 in 1/59
Lambda= 0.066366
statistics sampled from 41786 (42004) to 41786 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.492), width: 16
Scan time: 16.410
The best scores are: opt bits E(85289)
XP_005256963 (OMIM: 605315) PREDICTED: histone dea (1122) 4507 446.2 4.6e-124
NP_005465 (OMIM: 605315) histone deacetylase 5 iso (1122) 4507 446.2 4.6e-124
NP_001015053 (OMIM: 605315) histone deacetylase 5 (1123) 4495 445.1 1e-123
XP_005256962 (OMIM: 605315) PREDICTED: histone dea (1122) 4476 443.3 3.6e-123
XP_011522452 (OMIM: 605315) PREDICTED: histone dea (1113) 4444 440.2 3e-122
XP_016879479 (OMIM: 605315) PREDICTED: histone dea (1160) 4303 426.7 3.6e-118
XP_016879478 (OMIM: 605315) PREDICTED: histone dea (1161) 4303 426.7 3.6e-118
XP_016879477 (OMIM: 605315) PREDICTED: histone dea (1161) 4303 426.7 3.6e-118
XP_016879480 (OMIM: 605315) PREDICTED: histone dea (1160) 4284 424.9 1.3e-117
XP_016879481 (OMIM: 605315) PREDICTED: histone dea (1156) 4244 421.1 1.8e-116
XP_016879485 (OMIM: 605315) PREDICTED: histone dea (1081) 4239 420.6 2.4e-116
XP_011522451 (OMIM: 605315) PREDICTED: histone dea (1114) 3760 374.7 1.6e-102
XP_016879482 (OMIM: 605315) PREDICTED: histone dea (1152) 3747 373.5 3.8e-102
XP_016879484 (OMIM: 605315) PREDICTED: histone dea (1113) 3746 373.4 3.9e-102
XP_016879483 (OMIM: 605315) PREDICTED: histone dea (1120) 3746 373.4 4e-102
XP_016860883 (OMIM: 605314) PREDICTED: histone dea (1069) 1863 193.1 7.2e-48
XP_011510532 (OMIM: 605314) PREDICTED: histone dea ( 673) 1792 186.1 5.5e-46
XP_011510521 (OMIM: 605314) PREDICTED: histone dea (1103) 1796 186.7 6.3e-46
XP_011510520 (OMIM: 605314) PREDICTED: histone dea (1108) 1796 186.7 6.3e-46
XP_016860884 (OMIM: 605314) PREDICTED: histone dea ( 917) 1792 186.2 7e-46
XP_011510529 (OMIM: 605314) PREDICTED: histone dea (1041) 1792 186.3 7.8e-46
XP_006712943 (OMIM: 605314) PREDICTED: histone dea (1062) 1792 186.3 7.9e-46
XP_006712942 (OMIM: 605314) PREDICTED: histone dea (1062) 1792 186.3 7.9e-46
XP_011510528 (OMIM: 605314) PREDICTED: histone dea (1065) 1792 186.3 7.9e-46
XP_011510527 (OMIM: 605314) PREDICTED: histone dea (1079) 1792 186.3 8e-46
NP_006028 (OMIM: 605314) histone deacetylase 4 [Ho (1084) 1792 186.3 8.1e-46
XP_011510526 (OMIM: 605314) PREDICTED: histone dea (1084) 1792 186.3 8.1e-46
XP_011510523 (OMIM: 605314) PREDICTED: histone dea (1089) 1792 186.3 8.1e-46
XP_011510524 (OMIM: 605314) PREDICTED: histone dea (1089) 1792 186.3 8.1e-46
XP_011510525 (OMIM: 605314) PREDICTED: histone dea (1089) 1792 186.3 8.1e-46
XP_006712941 (OMIM: 605314) PREDICTED: histone dea (1089) 1792 186.3 8.1e-46
XP_011510522 (OMIM: 605314) PREDICTED: histone dea (1090) 1792 186.3 8.1e-46
XP_006712940 (OMIM: 605314) PREDICTED: histone dea (1108) 1792 186.3 8.2e-46
XP_011510519 (OMIM: 605314) PREDICTED: histone dea (1113) 1792 186.3 8.2e-46
NP_001308797 (OMIM: 606543) histone deacetylase 9 (1044) 1779 185.0 1.9e-45
NP_001308826 (OMIM: 606543) histone deacetylase 9 (1025) 1773 184.4 2.7e-45
NP_001308806 (OMIM: 606543) histone deacetylase 9 (1025) 1773 184.4 2.7e-45
XP_016868317 (OMIM: 606543) PREDICTED: histone dea (1025) 1773 184.4 2.7e-45
XP_011513936 (OMIM: 606543) PREDICTED: histone dea (1044) 1773 184.4 2.8e-45
XP_011513948 (OMIM: 606543) PREDICTED: histone dea (1035) 1726 179.9 6.2e-44
XP_011513946 (OMIM: 606543) PREDICTED: histone dea (1038) 1726 179.9 6.2e-44
XP_011513947 (OMIM: 606543) PREDICTED: histone dea (1038) 1726 179.9 6.2e-44
XP_011513944 (OMIM: 606543) PREDICTED: histone dea (1043) 1726 179.9 6.2e-44
XP_016868316 (OMIM: 606543) PREDICTED: histone dea (1043) 1726 179.9 6.2e-44
XP_011513943 (OMIM: 606543) PREDICTED: histone dea (1043) 1726 179.9 6.2e-44
NP_848510 (OMIM: 606543) histone deacetylase 9 iso (1066) 1726 180.0 6.3e-44
XP_016868315 (OMIM: 606543) PREDICTED: histone dea (1066) 1726 180.0 6.3e-44
XP_011513940 (OMIM: 606543) PREDICTED: histone dea (1069) 1726 180.0 6.4e-44
XP_011513941 (OMIM: 606543) PREDICTED: histone dea (1069) 1726 180.0 6.4e-44
NP_848512 (OMIM: 606543) histone deacetylase 9 iso (1069) 1726 180.0 6.4e-44
>>XP_005256963 (OMIM: 605315) PREDICTED: histone deacety (1122 aa)
initn: 4506 init1: 4506 opt: 4507 Z-score: 2348.3 bits: 446.2 E(85289): 4.6e-124
Smith-Waterman score: 6346; 92.0% identity (92.0% similar) in 1069 aa overlap (1-984:1-1069)
10 20 30 40 50 60
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
610 620 630 640 650 660
670 680
pF1KA0 SSPAAPGGMKSPPDQPVKHLFTTG------------------------------------
::::::::::::::::::::::::
XP_005 SSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQE
670 680 690 700 710 720
690
pF1KA0 -------------------------------------------------PISQKMYAVLP
:::::::::::
XP_005 TGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
730 740 750 760 770 780
700 710 720 730 740 750
pF1KA0 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
790 800 810 820 830 840
760 770 780 790 800 810
pF1KA0 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
850 860 870 880 890 900
820 830 840 850 860 870
pF1KA0 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
910 920 930 940 950 960
880 890 900 910 920 930
pF1KA0 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
970 980 990 1000 1010 1020
940 950 960 970 980 990
pF1KA0 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
1030 1040 1050 1060 1070 1080
1000 1010 1020 1030
pF1KA0 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
XP_005 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
1090 1100 1110 1120
>>NP_005465 (OMIM: 605315) histone deacetylase 5 isoform (1122 aa)
initn: 4506 init1: 4506 opt: 4507 Z-score: 2348.3 bits: 446.2 E(85289): 4.6e-124
Smith-Waterman score: 6346; 92.0% identity (92.0% similar) in 1069 aa overlap (1-984:1-1069)
10 20 30 40 50 60
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
610 620 630 640 650 660
670 680
pF1KA0 SSPAAPGGMKSPPDQPVKHLFTTG------------------------------------
::::::::::::::::::::::::
NP_005 SSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQE
670 680 690 700 710 720
690
pF1KA0 -------------------------------------------------PISQKMYAVLP
:::::::::::
NP_005 TGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
730 740 750 760 770 780
700 710 720 730 740 750
pF1KA0 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
790 800 810 820 830 840
760 770 780 790 800 810
pF1KA0 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
850 860 870 880 890 900
820 830 840 850 860 870
pF1KA0 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
910 920 930 940 950 960
880 890 900 910 920 930
pF1KA0 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
970 980 990 1000 1010 1020
940 950 960 970 980 990
pF1KA0 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
1030 1040 1050 1060 1070 1080
1000 1010 1020 1030
pF1KA0 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
NP_005 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
1090 1100 1110 1120
>>NP_001015053 (OMIM: 605315) histone deacetylase 5 isof (1123 aa)
initn: 4460 init1: 4460 opt: 4495 Z-score: 2342.1 bits: 445.1 E(85289): 1e-123
Smith-Waterman score: 6334; 92.0% identity (92.0% similar) in 1070 aa overlap (1-984:1-1070)
10 20 30 40 50
pF1KA0 MNSPNES-DGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVEL
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVEL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 RGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 QQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA0 STEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA0 LPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA0 ITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPN
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 QFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 TSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVAT
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 SMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 ELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEE
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 DCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRT
610 620 630 640 650 660
660 670 680
pF1KA0 QSSPAAPGGMKSPPDQPVKHLFTTG-----------------------------------
:::::::::::::::::::::::::
NP_001 QSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQ
670 680 690 700 710 720
690
pF1KA0 --------------------------------------------------PISQKMYAVL
::::::::::
NP_001 ETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVL
730 740 750 760 770 780
700 710 720 730 740 750
pF1KA0 PCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTA
790 800 810 820 830 840
760 770 780 790 800 810
pF1KA0 MGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGN
850 860 870 880 890 900
820 830 840 850 860 870
pF1KA0 FFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLV
910 920 930 940 950 960
880 890 900 910 920 930
pF1KA0 SAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACV
970 980 990 1000 1010 1020
940 950 960 970 980 990
pF1KA0 SALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGE
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGE
1030 1040 1050 1060 1070 1080
1000 1010 1020 1030
pF1KA0 TEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
NP_001 TEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
1090 1100 1110 1120
>>XP_005256962 (OMIM: 605315) PREDICTED: histone deacety (1122 aa)
initn: 3738 init1: 3738 opt: 4476 Z-score: 2332.2 bits: 443.3 E(85289): 3.6e-123
Smith-Waterman score: 6315; 91.9% identity (91.9% similar) in 1070 aa overlap (1-984:1-1069)
10 20 30 40 50
pF1KA0 MNSPNES-DGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVEL
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVEL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 RGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 QQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIA
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 Q-EMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIA
130 140 150 160 170
180 190 200 210 220 230
pF1KA0 STEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KA0 LPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 ITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KA0 QFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMS
360 370 380 390 400 410
420 430 440 450 460 470
pF1KA0 TSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVAT
420 430 440 450 460 470
480 490 500 510 520 530
pF1KA0 SMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTG
480 490 500 510 520 530
540 550 560 570 580 590
pF1KA0 ELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEE
540 550 560 570 580 590
600 610 620 630 640 650
pF1KA0 DCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRT
600 610 620 630 640 650
660 670 680
pF1KA0 QSSPAAPGGMKSPPDQPVKHLFTTG-----------------------------------
:::::::::::::::::::::::::
XP_005 QSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQ
660 670 680 690 700 710
690
pF1KA0 --------------------------------------------------PISQKMYAVL
::::::::::
XP_005 ETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVL
720 730 740 750 760 770
700 710 720 730 740 750
pF1KA0 PCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTA
780 790 800 810 820 830
760 770 780 790 800 810
pF1KA0 MGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGN
840 850 860 870 880 890
820 830 840 850 860 870
pF1KA0 FFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLV
900 910 920 930 940 950
880 890 900 910 920 930
pF1KA0 SAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACV
960 970 980 990 1000 1010
940 950 960 970 980 990
pF1KA0 SALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGE
1020 1030 1040 1050 1060 1070
1000 1010 1020 1030
pF1KA0 TEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
XP_005 TEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
1080 1090 1100 1110 1120
>>XP_011522452 (OMIM: 605315) PREDICTED: histone deacety (1113 aa)
initn: 4443 init1: 4443 opt: 4444 Z-score: 2315.7 bits: 440.2 E(85289): 3e-122
Smith-Waterman score: 6283; 92.0% identity (92.0% similar) in 1060 aa overlap (10-984:1-1060)
10 20 30 40 50 60
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
600 610 620 630 640 650
670 680
pF1KA0 SSPAAPGGMKSPPDQPVKHLFTTG------------------------------------
::::::::::::::::::::::::
XP_011 SSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQE
660 670 680 690 700 710
690
pF1KA0 -------------------------------------------------PISQKMYAVLP
:::::::::::
XP_011 TGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
720 730 740 750 760 770
700 710 720 730 740 750
pF1KA0 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
780 790 800 810 820 830
760 770 780 790 800 810
pF1KA0 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
840 850 860 870 880 890
820 830 840 850 860 870
pF1KA0 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
900 910 920 930 940 950
880 890 900 910 920 930
pF1KA0 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
960 970 980 990 1000 1010
940 950 960 970 980 990
pF1KA0 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
1020 1030 1040 1050 1060 1070
1000 1010 1020 1030
pF1KA0 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
XP_011 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
1080 1090 1100 1110
>>XP_016879479 (OMIM: 605315) PREDICTED: histone deacety (1160 aa)
initn: 4302 init1: 4302 opt: 4303 Z-score: 2242.5 bits: 426.7 E(85289): 3.6e-118
Smith-Waterman score: 6218; 88.8% identity (88.8% similar) in 1101 aa overlap (7-984:7-1107)
10 20 30
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTV----------------------------
::::::::::::::::::::::::::
XP_016 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQEL
10 20 30 40 50 60
40 50 60 70 80
pF1KA0 ----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLA
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLA
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 LKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELE
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 QQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 LNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPN
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 LKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSP
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 NSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTV
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 TNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHA
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 SLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLP
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 QSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEV
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 LLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEP
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 GAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFT
670 680 690 700 710 720
pF1KA0 TG----------------------------------------------------------
::
XP_016 TGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQT
730 740 750 760 770 780
690 700 710
pF1KA0 ---------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVR
:::::::::::::::::::::::::::::::::
XP_016 VHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVR
790 800 810 820 830 840
720 730 740 750 760 770
pF1KA0 MAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVG
850 860 870 880 890 900
780 790 800 810 820 830
pF1KA0 KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNV
910 920 930 940 950 960
840 850 860 870 880 890
pF1KA0 AWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARC
970 980 990 1000 1010 1020
900 910 920 930 940 950
pF1KA0 FGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNIN
1030 1040 1050 1060 1070 1080
960 970 980 990 1000 1010
pF1KA0 AVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAA
:::::::::::::::::::::::::::
XP_016 AVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAA
1090 1100 1110 1120 1130 1140
>>XP_016879478 (OMIM: 605315) PREDICTED: histone deacety (1161 aa)
initn: 4302 init1: 4302 opt: 4303 Z-score: 2242.5 bits: 426.7 E(85289): 3.6e-118
Smith-Waterman score: 6214; 88.7% identity (88.8% similar) in 1101 aa overlap (7-984:8-1108)
10 20 30
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTV---------------------------
.:::::::::::::::::::::::::
XP_016 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQE
10 20 30 40 50 60
40 50 60 70 80
pF1KA0 -----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
670 680 690 700 710 720
pF1KA0 TTG---------------------------------------------------------
:::
XP_016 TTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQ
730 740 750 760 770 780
690 700 710
pF1KA0 ----------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
::::::::::::::::::::::::::::::::
XP_016 TVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
790 800 810 820 830 840
720 730 740 750 760 770
pF1KA0 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
850 860 870 880 890 900
780 790 800 810 820 830
pF1KA0 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
910 920 930 940 950 960
840 850 860 870 880 890
pF1KA0 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
970 980 990 1000 1010 1020
900 910 920 930 940 950
pF1KA0 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
1030 1040 1050 1060 1070 1080
960 970 980 990 1000 1010
pF1KA0 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
::::::::::::::::::::::::::::
XP_016 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
1090 1100 1110 1120 1130 1140
>>XP_016879477 (OMIM: 605315) PREDICTED: histone deacety (1161 aa)
initn: 4302 init1: 4302 opt: 4303 Z-score: 2242.5 bits: 426.7 E(85289): 3.6e-118
Smith-Waterman score: 6214; 88.7% identity (88.8% similar) in 1101 aa overlap (7-984:8-1108)
10 20 30
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTV---------------------------
.:::::::::::::::::::::::::
XP_016 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQE
10 20 30 40 50 60
40 50 60 70 80
pF1KA0 -----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
670 680 690 700 710 720
pF1KA0 TTG---------------------------------------------------------
:::
XP_016 TTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQ
730 740 750 760 770 780
690 700 710
pF1KA0 ----------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
::::::::::::::::::::::::::::::::
XP_016 TVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
790 800 810 820 830 840
720 730 740 750 760 770
pF1KA0 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
850 860 870 880 890 900
780 790 800 810 820 830
pF1KA0 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
910 920 930 940 950 960
840 850 860 870 880 890
pF1KA0 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
970 980 990 1000 1010 1020
900 910 920 930 940 950
pF1KA0 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
1030 1040 1050 1060 1070 1080
960 970 980 990 1000 1010
pF1KA0 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
::::::::::::::::::::::::::::
XP_016 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
1090 1100 1110 1120 1130 1140
>>XP_016879480 (OMIM: 605315) PREDICTED: histone deacety (1160 aa)
initn: 3887 init1: 3738 opt: 4284 Z-score: 2232.7 bits: 424.9 E(85289): 1.3e-117
Smith-Waterman score: 6195; 88.6% identity (88.7% similar) in 1101 aa overlap (7-984:8-1107)
10 20 30
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTV---------------------------
.:::::::::::::::::::::::::
XP_016 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQE
10 20 30 40 50 60
40 50 60 70 80
pF1KA0 -----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ-EMLAAKQQQEMLAAKRQQEL
130 140 150 160 170
150 160 170 180 190 200
pF1KA0 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
180 190 200 210 220 230
210 220 230 240 250 260
pF1KA0 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KA0 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
300 310 320 330 340 350
330 340 350 360 370 380
pF1KA0 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
360 370 380 390 400 410
390 400 410 420 430 440
pF1KA0 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KA0 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
480 490 500 510 520 530
510 520 530 540 550 560
pF1KA0 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KA0 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KA0 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
660 670 680 690 700 710
pF1KA0 TTG---------------------------------------------------------
:::
XP_016 TTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQ
720 730 740 750 760 770
690 700 710
pF1KA0 ----------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
::::::::::::::::::::::::::::::::
XP_016 TVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
780 790 800 810 820 830
720 730 740 750 760 770
pF1KA0 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
840 850 860 870 880 890
780 790 800 810 820 830
pF1KA0 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
900 910 920 930 940 950
840 850 860 870 880 890
pF1KA0 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
960 970 980 990 1000 1010
900 910 920 930 940 950
pF1KA0 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
1020 1030 1040 1050 1060 1070
960 970 980 990 1000 1010
pF1KA0 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
::::::::::::::::::::::::::::
XP_016 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
1080 1090 1100 1110 1120 1130
>>XP_016879481 (OMIM: 605315) PREDICTED: histone deacety (1156 aa)
initn: 4124 init1: 2483 opt: 4244 Z-score: 2212.0 bits: 421.1 E(85289): 1.8e-116
Smith-Waterman score: 6175; 88.3% identity (88.3% similar) in 1106 aa overlap (3-984:3-1103)
10 20 30
pF1KA0 MNSPNES-DGMSGREPSLEILPRTSLHSIPVTV---------------------------
::::: :::::::::::::::::::::::::
XP_016 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQE
10 20 30 40 50 60
40 50 60 70 80
pF1KA0 -----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEIT-----ASSVCNSAPGSGPSS
310 320 330 340 350
330 340 350 360 370 380
pF1KA0 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
360 370 380 390 400 410
390 400 410 420 430 440
pF1KA0 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
420 430 440 450 460 470
450 460 470 480 490 500
pF1KA0 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
480 490 500 510 520 530
510 520 530 540 550 560
pF1KA0 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KA0 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
600 610 620 630 640 650
630 640 650 660 670 680
pF1KA0 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
660 670 680 690 700 710
pF1KA0 TTG---------------------------------------------------------
:::
XP_016 TTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQ
720 730 740 750 760 770
690 700 710
pF1KA0 ----------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
::::::::::::::::::::::::::::::::
XP_016 TVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
780 790 800 810 820 830
720 730 740 750 760 770
pF1KA0 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
840 850 860 870 880 890
780 790 800 810 820 830
pF1KA0 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
900 910 920 930 940 950
840 850 860 870 880 890
pF1KA0 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
960 970 980 990 1000 1010
900 910 920 930 940 950
pF1KA0 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
1020 1030 1040 1050 1060 1070
960 970 980 990 1000 1010
pF1KA0 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
::::::::::::::::::::::::::::
XP_016 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
1080 1090 1100 1110 1120 1130
1037 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:49:16 2016 done: Fri Nov 4 00:49:18 2016
Total Scan time: 16.410 Total Display time: 0.420
Function used was FASTA [36.3.4 Apr, 2011]