Result of FASTA (omim) for
pFN21AB9426
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9426, 683 aa
1>>>pF1KB9426 683 - 683 aa - 683 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.2457+/-0.000755; mu= -42.5318+/- 0.044
mean_var=875.3852+/-190.957, 0's: 0 Z-trim(112.9): 1519 B-trim: 0 in 0/54
Lambda= 0.043349
statistics sampled from 20086 (21960) to 20086 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.257), width: 16
Scan time: 9.220
The best scores are: opt bits E(85289)
NP_006246 (OMIM: 601367,605437) protein kinase C e ( 683) 4721 312.5 3.4e-84
XP_011535256 (OMIM: 601367,605437) PREDICTED: prot ( 604) 3919 262.3 3.9e-69
XP_011535257 (OMIM: 601367,605437) PREDICTED: prot ( 603) 3901 261.2 8.5e-69
XP_016876947 (OMIM: 601367,605437) PREDICTED: prot ( 522) 3647 245.2 4.6e-64
XP_011535258 (OMIM: 601367,605437) PREDICTED: prot ( 524) 3278 222.1 4.1e-57
XP_011535259 (OMIM: 601367,605437) PREDICTED: prot ( 489) 3272 221.7 5e-57
XP_016876948 (OMIM: 601367,605437) PREDICTED: prot ( 444) 2960 202.2 3.5e-51
XP_011531285 (OMIM: 176975) PREDICTED: protein kin ( 436) 1747 126.3 2.4e-28
XP_006712113 (OMIM: 176975) PREDICTED: protein kin ( 460) 1747 126.4 2.5e-28
XP_011531284 (OMIM: 176975) PREDICTED: protein kin ( 497) 1747 126.4 2.6e-28
XP_011531282 (OMIM: 176975) PREDICTED: protein kin ( 587) 1747 126.4 3e-28
XP_016859980 (OMIM: 176975) PREDICTED: protein kin ( 587) 1747 126.4 3e-28
XP_011531283 (OMIM: 176975) PREDICTED: protein kin ( 587) 1747 126.4 3e-28
XP_016859978 (OMIM: 176975) PREDICTED: protein kin ( 587) 1747 126.4 3e-28
XP_016859979 (OMIM: 176975) PREDICTED: protein kin ( 587) 1747 126.4 3e-28
XP_016859977 (OMIM: 176975) PREDICTED: protein kin ( 623) 1747 126.5 3.1e-28
XP_016859976 (OMIM: 176975) PREDICTED: protein kin ( 623) 1747 126.5 3.1e-28
XP_011531280 (OMIM: 176975) PREDICTED: protein kin ( 623) 1747 126.5 3.1e-28
XP_016859975 (OMIM: 176975) PREDICTED: protein kin ( 641) 1747 126.5 3.2e-28
XP_011531273 (OMIM: 176975) PREDICTED: protein kin ( 641) 1747 126.5 3.2e-28
XP_011531277 (OMIM: 176975) PREDICTED: protein kin ( 641) 1747 126.5 3.2e-28
XP_005264485 (OMIM: 176975) PREDICTED: protein kin ( 737) 1747 126.5 3.5e-28
NP_005391 (OMIM: 176975) protein kinase C epsilon ( 737) 1747 126.5 3.5e-28
NP_001303256 (OMIM: 176977,615559) protein kinase ( 676) 1505 111.4 1.2e-23
XP_006713322 (OMIM: 176977,615559) PREDICTED: prot ( 676) 1505 111.4 1.2e-23
NP_006245 (OMIM: 176977,615559) protein kinase C d ( 676) 1505 111.4 1.2e-23
NP_997704 (OMIM: 176977,615559) protein kinase C d ( 676) 1505 111.4 1.2e-23
XP_016862345 (OMIM: 176977,615559) PREDICTED: prot ( 676) 1505 111.4 1.2e-23
XP_016862344 (OMIM: 176977,615559) PREDICTED: prot ( 676) 1505 111.4 1.2e-23
XP_006713320 (OMIM: 176977,615559) PREDICTED: prot ( 692) 1505 111.4 1.2e-23
XP_016859981 (OMIM: 176975) PREDICTED: protein kin ( 481) 1444 107.4 1.3e-22
XP_005264488 (OMIM: 176975) PREDICTED: protein kin ( 496) 1444 107.4 1.3e-22
NP_997700 (OMIM: 176970) protein kinase C beta typ ( 671) 1367 102.7 4.7e-21
XP_016880329 (OMIM: 176960) PREDICTED: protein kin ( 586) 1354 101.9 7.4e-21
XP_016880327 (OMIM: 176960) PREDICTED: protein kin ( 586) 1354 101.9 7.4e-21
XP_016880328 (OMIM: 176960) PREDICTED: protein kin ( 586) 1354 101.9 7.4e-21
XP_016880326 (OMIM: 176960) PREDICTED: protein kin ( 621) 1354 101.9 7.7e-21
NP_002728 (OMIM: 176960) protein kinase C alpha ty ( 672) 1355 102.0 7.8e-21
NP_002729 (OMIM: 176970) protein kinase C beta typ ( 673) 1345 101.4 1.2e-20
NP_001269574 (OMIM: 600448) protein kinase C theta ( 581) 1311 99.2 4.7e-20
XP_016871900 (OMIM: 600448) PREDICTED: protein kin ( 581) 1311 99.2 4.7e-20
NP_001310195 (OMIM: 600448) protein kinase C theta ( 581) 1311 99.2 4.7e-20
NP_001269573 (OMIM: 600448) protein kinase C theta ( 670) 1311 99.2 5.3e-20
XP_016871899 (OMIM: 600448) PREDICTED: protein kin ( 706) 1311 99.2 5.5e-20
NP_006248 (OMIM: 600448) protein kinase C theta ty ( 706) 1311 99.2 5.5e-20
NP_001310194 (OMIM: 600448) protein kinase C theta ( 706) 1311 99.2 5.5e-20
XP_006717528 (OMIM: 600448) PREDICTED: protein kin ( 706) 1311 99.2 5.5e-20
XP_005252553 (OMIM: 600448) PREDICTED: protein kin ( 740) 1311 99.3 5.7e-20
NP_002730 (OMIM: 176980,605361) protein kinase C g ( 697) 1284 97.5 1.8e-19
NP_001303258 (OMIM: 176980,605361) protein kinase ( 710) 1284 97.6 1.8e-19
>>NP_006246 (OMIM: 601367,605437) protein kinase C eta t (683 aa)
initn: 4721 init1: 4721 opt: 4721 Z-score: 1632.6 bits: 312.5 E(85289): 3.4e-84
Smith-Waterman score: 4721; 100.0% identity (100.0% similar) in 683 aa overlap (1-683:1-683)
10 20 30 40 50 60
pF1KB9 MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 KLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 GVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 TQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDE
610 620 630 640 650 660
670 680
pF1KB9 GHLPMINQDEFRNFSYVSPELQP
:::::::::::::::::::::::
NP_006 GHLPMINQDEFRNFSYVSPELQP
670 680
>>XP_011535256 (OMIM: 601367,605437) PREDICTED: protein (604 aa)
initn: 3916 init1: 3916 opt: 3919 Z-score: 1362.2 bits: 262.3 E(85289): 3.9e-69
Smith-Waterman score: 3919; 98.3% identity (99.3% similar) in 576 aa overlap (108-683:31-604)
80 90 100 110 120 130
pF1KB9 DGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEGWVDLEPEGKVFVVITLT
:::. ... .. :::::::::::::::::
XP_011 MNHGSRSGAGVDPGETSRVDVLGSESDSMYLLRSWASGVAY--WVDLEPEGKVFVVITLT
10 20 30 40 50
140 150 160 170 180 190
pF1KB9 GSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLRQPTYCSHCREFIWGVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLRQPTYCSHCREFIWGVFG
60 70 80 90 100 110
200 210 220 230 240 250
pF1KB9 KQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIHNYKVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIHNYKVPT
120 130 140 150 160 170
260 270 280 290 300 310
pF1KB9 FCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNIS
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB9 PTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKET
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB9 GDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVN
300 310 320 330 340 350
440 450 460 470 480 490
pF1KB9 GGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLAD
360 370 380 390 400 410
500 510 520 530 540 550
pF1KB9 FGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAE
420 430 440 450 460 470
560 570 580 590 600 610
pF1KB9 NEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEI
480 490 500 510 520 530
620 630 640 650 660 670
pF1KB9 DWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYV
540 550 560 570 580 590
680
pF1KB9 SPELQP
::::::
XP_011 SPELQP
600
>>XP_011535257 (OMIM: 601367,605437) PREDICTED: protein (603 aa)
initn: 3901 init1: 3901 opt: 3901 Z-score: 1356.1 bits: 261.2 E(85289): 8.5e-69
Smith-Waterman score: 3901; 100.0% identity (100.0% similar) in 562 aa overlap (122-683:42-603)
100 110 120 130 140 150
pF1KB9 LGYDHFVANCTLQFQELLRTTGASDTFEGWVDLEPEGKVFVVITLTGSFTEATLQRDRIF
::::::::::::::::::::::::::::::
XP_011 MQRTTPYEKTSSCIACRMHVLIFQLIGNFKVDLEPEGKVFVVITLTGSFTEATLQRDRIF
20 30 40 50 60 70
160 170 180 190 200 210
pF1KB9 KHFTRKRQRAMRRRVHQINGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHFTRKRQRAMRRRVHQINGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVH
80 90 100 110 120 130
220 230 240 250 260 270
pF1KB9 KRCHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMR
140 150 160 170 180 190
280 290 300 310 320 330
pF1KB9 QGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTSKLVSRSTLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTSKLVSRSTLRRQ
200 210 220 230 240 250
340 350 360 370 380 390
pF1KB9 GKESSKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKESSKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVI
260 270 280 290 300 310
400 410 420 430 440 450
pF1KB9 LQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRF
320 330 340 350 360 370
460 470 480 490 500 510
pF1KB9 DEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTT
380 390 400 410 420 430
520 530 540 550 560 570
pF1KB9 ATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEV
440 450 460 470 480 490
580 590 600 610 620 630
pF1KB9 VYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPF
500 510 520 530 540 550
640 650 660 670 680
pF1KB9 RPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP
560 570 580 590 600
>>XP_016876947 (OMIM: 601367,605437) PREDICTED: protein (522 aa)
initn: 3647 init1: 3647 opt: 3647 Z-score: 1271.1 bits: 245.2 E(85289): 4.6e-64
Smith-Waterman score: 3647; 100.0% identity (100.0% similar) in 522 aa overlap (162-683:1-522)
140 150 160 170 180 190
pF1KB9 VVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLRQPTYCSHCREF
::::::::::::::::::::::::::::::
XP_016 MRRRVHQINGHKFMATYLRQPTYCSHCREF
10 20 30
200 210 220 230 240 250
pF1KB9 IWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIH
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB9 NYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGL
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB9 QPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVML
160 170 180 190 200 210
380 390 400 410 420 430
pF1KB9 ARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFF
220 230 240 250 260 270
440 450 460 470 480 490
pF1KB9 VMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEG
280 290 300 310 320 330
500 510 520 530 540 550
pF1KB9 HCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGH
340 350 360 370 380 390
560 570 580 590 600 610
pF1KB9 APFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRH
400 410 420 430 440 450
620 630 640 650 660 670
pF1KB9 PFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEF
460 470 480 490 500 510
680
pF1KB9 RNFSYVSPELQP
::::::::::::
XP_016 RNFSYVSPELQP
520
>>XP_011535258 (OMIM: 601367,605437) PREDICTED: protein (524 aa)
initn: 3265 init1: 3265 opt: 3278 Z-score: 1146.4 bits: 222.1 E(85289): 4.1e-57
Smith-Waterman score: 3278; 94.0% identity (95.0% similar) in 521 aa overlap (1-518:1-514)
10 20 30 40 50 60
pF1KB9 MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIY---
430 440 450 460 470
490 500 510 520 530
pF1KB9 KLDNVLLDHEGHCKLADFGMCKE-GICNGVT-TATF-CGTPDYIAPEILQEMLYGPAVDW
.. :: : : : : . .. : : :: :: :
XP_011 --STSCQDHAGAAKKED--RCTDRAFWNTVRGQPTFSCGQPILNGRIILEP
480 490 500 510 520
540 550 560 570 580 590
pF1KB9 WAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRL
>>XP_011535259 (OMIM: 601367,605437) PREDICTED: protein (489 aa)
initn: 3272 init1: 3272 opt: 3272 Z-score: 1144.8 bits: 221.7 E(85289): 5e-57
Smith-Waterman score: 3272; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478)
10 20 30 40 50 60
pF1KB9 MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRTA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 KLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAM
XP_011 YIFLWSAHS
>>XP_016876948 (OMIM: 601367,605437) PREDICTED: protein (444 aa)
initn: 3121 init1: 2960 opt: 2960 Z-score: 1039.9 bits: 202.2 E(85289): 3.5e-51
Smith-Waterman score: 2960; 99.5% identity (99.5% similar) in 434 aa overlap (1-434:1-434)
10 20 30 40 50 60
pF1KB9 MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDL
:::::::::: : :
XP_016 CCFQTPDRLFNVSEGWHAAGSSQQ
430 440
>>XP_011531285 (OMIM: 176975) PREDICTED: protein kinase (436 aa)
initn: 1731 init1: 1394 opt: 1747 Z-score: 630.0 bits: 126.3 E(85289): 2.4e-28
Smith-Waterman score: 1747; 68.7% identity (89.8% similar) in 361 aa overlap (325-683:76-436)
300 310 320 330 340 350
pF1KB9 CGVNAVELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNG-IGVNSSNRLGID
:.. .:. : :: . ....:::.:
XP_011 APTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAKRLGLD
50 60 70 80 90 100
360 370 380 390 400 410
pF1KB9 NFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNH
.:.::.:::::::::::::..: ..:::::::::::::::::.:::::::::.:::.:
XP_011 EFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKH
110 120 130 140 150 160
420 430 440 450 460 470
pF1KB9 PFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDK
:.::::.::::: ::::::::.::::::::.::.::.::: :.::::::. :::::::..
XP_011 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQH
170 180 190 200 210 220
480 490 500 510 520 530
pF1KB9 GIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGP
:.:::::::::.::: :::::::::::::::: :::::.::::::::::::::::. :::
XP_011 GVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGP
230 240 250 260 270 280
540 550 560 570 580 590
pF1KB9 AVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNP
.:::::.:::.:::. :. ::::.:::::::.::.:.:.::.:: ..:..:::.::::::
XP_011 SVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNP
290 300 310 320 330 340
600 610 620 630 640 650
pF1KB9 TMRLGSL-TQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEE
::: . .:.:: :: .:::::::::. :....:.:::.::::...::.::: :: .::
XP_011 HKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREE
350 360 370 380 390 400
660 670 680
pF1KB9 PVLTPIDEGHLPMINQDEFRNFSYVSPELQP
:::: .::. . .:::.::..::: . .:.:
XP_011 PVLTLVDEAIVKQINQEEFKGFSYFGEDLMP
410 420 430
>>XP_006712113 (OMIM: 176975) PREDICTED: protein kinase (460 aa)
initn: 1876 init1: 1394 opt: 1747 Z-score: 629.7 bits: 126.4 E(85289): 2.5e-28
Smith-Waterman score: 1808; 60.2% identity (79.6% similar) in 460 aa overlap (281-683:1-460)
260 270 280 290 300 310
pF1KB9 HNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMG
:::: ::..::::::::.: .::.:: .:
XP_006 MNVHRRCETNVAPNCGVDARGIAKVLADLG
10 20 30
320 330
pF1KB9 LQPGNI-----------------------SPTSKLVSRST---------------LRR--
. : .: ::. . :.:. .:.
XP_006 VTPDKITNSGQRRKKLIAGAESPQPASGSSPSEEDRSKSAPTSPCDQEIKELENNIRKAL
40 50 60 70 80 90
340 350 360 370
pF1KB9 ----QGKE----SSKEG-------NG-IGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARV
.:.: :: .: :: . ....:::.:.:.::.:::::::::::::..
XP_006 SFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAEL
100 110 120 130 140 150
380 390 400 410 420 430
pF1KB9 KETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVME
: ..:::::::::::::::::.:::::::::.:::.::.::::.::::: ::::::::
XP_006 KGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVME
160 170 180 190 200 210
440 450 460 470 480 490
pF1KB9 FVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCK
.::::::::.::.::.::: :.::::::. :::::::..:.:::::::::.::: :::::
XP_006 YVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCK
220 230 240 250 260 270
500 510 520 530 540 550
pF1KB9 LADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPF
::::::::::: :::::.::::::::::::::::. :::.:::::.:::.:::. :. ::
XP_006 LADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPF
280 290 300 310 320 330
560 570 580 590 600 610
pF1KB9 EAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSL-TQGGEHAILRHPF
::.:::::::.::.:.:.::.:: ..:..:::.:::::: ::: . .:.:: :: .:::
XP_006 EADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPF
340 350 360 370 380 390
620 630 640 650 660 670
pF1KB9 FKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRN
::::::. :....:.:::.::::...::.::: :: .:::::: .::. . .:::.::..
XP_006 FKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKG
400 410 420 430 440 450
680
pF1KB9 FSYVSPELQP
::: . .:.:
XP_006 FSYFGEDLMP
460
>>XP_011531284 (OMIM: 176975) PREDICTED: protein kinase (497 aa)
initn: 2147 init1: 1394 opt: 1747 Z-score: 629.2 bits: 126.4 E(85289): 2.6e-28
Smith-Waterman score: 2079; 62.2% identity (81.1% similar) in 497 aa overlap (244-683:1-497)
220 230 240 250 260 270
pF1KB9 CHHLIVTACTCQNNINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQG
.::::.:::::::::::::::::::..:::
XP_011 MPHKFGIHNYKVPTFCDHCGSLLWGLLRQG
10 20 30
280 290 300 310
pF1KB9 LQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNI-----------------
::::.:::::: ::..::::::::.: .::.:: .:. : .:
XP_011 LQCKVCKMNVHRRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESP
40 50 60 70 80 90
320 330
pF1KB9 ------SPTSKLVSRST---------------LRR------QGKE----SSKEG------
::. . :.:. .:. .:.: :: .:
XP_011 QPASGSSPSEEDRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPG
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB9 -NG-IGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDV
:: . ....:::.:.:.::.:::::::::::::..: ..:::::::::::::::::
XP_011 ENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDV
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB9 ECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARAR
.:::::::::.:::.::.::::.::::: ::::::::.::::::::.::.::.::: :.:
XP_011 DCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSR
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB9 FYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGT
:::::. :::::::..:.:::::::::.::: :::::::::::::::: :::::.:::::
XP_011 FYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGT
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB9 PDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWL
:::::::::::. :::.:::::.:::.:::. :. ::::.:::::::.::.:.:.::.::
XP_011 PDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWL
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB9 HEDATGILKSFMTKNPTMRLGSL-TQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIK
..:..:::.:::::: ::: . .:.:: :: .:::::::::. :....:.:::.::::
XP_011 SKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIK
400 410 420 430 440 450
640 650 660 670 680
pF1KB9 SREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP
...::.::: :: .:::::: .::. . .:::.::..::: . .:.:
XP_011 TKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP
460 470 480 490
683 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:19:31 2016 done: Thu Nov 3 23:19:32 2016
Total Scan time: 9.220 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]