Result of FASTA (omim) for
pFN21AB3619
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3619, 902 aa
1>>>pF1KB3619 902 - 902 aa - 902 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5140+/-0.000419; mu= 15.6130+/- 0.026
mean_var=113.1426+/-23.254, 0's: 0 Z-trim(114.7): 195 B-trim: 684 in 1/54
Lambda= 0.120576
statistics sampled from 24407 (24654) to 24407 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.289), width: 16
Scan time: 13.490
The best scores are: opt bits E(85289)
NP_001305713 (OMIM: 300535,300555,309000) inositol ( 902) 6123 1077.0 0
NP_000267 (OMIM: 300535,300555,309000) inositol po ( 901) 6101 1073.1 0
NP_001578 (OMIM: 300535,300555,309000) inositol po ( 893) 6025 1059.9 0
XP_011529646 (OMIM: 300535,300555,309000) PREDICTE ( 853) 5579 982.3 0
XP_011529647 (OMIM: 300535,300555,309000) PREDICTE ( 853) 5579 982.3 0
XP_016885043 (OMIM: 300535,300555,309000) PREDICTE ( 831) 5292 932.4 0
XP_005262479 (OMIM: 300535,300555,309000) PREDICTE ( 744) 5055 891.1 0
NP_001284363 (OMIM: 147264) type II inositol 1,4,5 ( 749) 2078 373.3 2.5e-102
XP_016856696 (OMIM: 147264) PREDICTED: type II ino ( 794) 2078 373.3 2.6e-102
XP_016856695 (OMIM: 147264) PREDICTED: type II ino ( 823) 2078 373.3 2.7e-102
XP_006710684 (OMIM: 147264) PREDICTED: type II ino ( 848) 2078 373.3 2.8e-102
NP_005531 (OMIM: 147264) type II inositol 1,4,5-tr ( 913) 2078 373.3 2.9e-102
XP_011539694 (OMIM: 147264) PREDICTED: type II ino ( 720) 2074 372.5 4e-102
XP_011539695 (OMIM: 147264) PREDICTED: type II ino ( 720) 2074 372.5 4e-102
XP_016856698 (OMIM: 147264) PREDICTED: type II ino ( 693) 2073 372.4 4.3e-102
XP_016856697 (OMIM: 147264) PREDICTED: type II ino ( 693) 2073 372.4 4.3e-102
XP_005267256 (OMIM: 609410) PREDICTED: synaptojani (1113) 663 127.2 4.3e-28
XP_016866895 (OMIM: 609410) PREDICTED: synaptojani (1113) 663 127.2 4.3e-28
XP_011534530 (OMIM: 609410) PREDICTED: synaptojani (1113) 663 127.2 4.3e-28
XP_011534529 (OMIM: 609410) PREDICTED: synaptojani (1158) 663 127.2 4.4e-28
XP_005267255 (OMIM: 609410) PREDICTED: synaptojani (1165) 663 127.2 4.5e-28
XP_011534528 (OMIM: 609410) PREDICTED: synaptojani (1165) 663 127.2 4.5e-28
XP_011534532 (OMIM: 609410) PREDICTED: synaptojani (1243) 663 127.3 4.7e-28
NP_001171559 (OMIM: 609410) synaptojanin-2 isoform (1259) 663 127.3 4.7e-28
XP_011534527 (OMIM: 609410) PREDICTED: synaptojani (1259) 663 127.3 4.7e-28
XP_006715655 (OMIM: 609410) PREDICTED: synaptojani (1288) 663 127.3 4.8e-28
XP_011534526 (OMIM: 609410) PREDICTED: synaptojani (1451) 663 127.3 5.3e-28
NP_003889 (OMIM: 609410) synaptojanin-2 isoform 1 (1496) 663 127.3 5.4e-28
XP_016883993 (OMIM: 604297,615530) PREDICTED: syna (1269) 626 120.8 4.1e-26
XP_016883992 (OMIM: 604297,615530) PREDICTED: syna (1282) 626 120.8 4.2e-26
XP_016883991 (OMIM: 604297,615530) PREDICTED: syna (1294) 626 120.8 4.2e-26
NP_001153774 (OMIM: 604297,615530) synaptojanin-1 (1295) 626 120.8 4.2e-26
XP_016883994 (OMIM: 604297,615530) PREDICTED: syna (1303) 626 120.8 4.2e-26
XP_016883990 (OMIM: 604297,615530) PREDICTED: syna (1310) 626 120.8 4.2e-26
XP_016883989 (OMIM: 604297,615530) PREDICTED: syna (1311) 626 120.8 4.2e-26
NP_982271 (OMIM: 604297,615530) synaptojanin-1 iso (1350) 626 120.9 4.3e-26
NP_001153778 (OMIM: 604297,615530) synaptojanin-1 (1526) 626 120.9 4.8e-26
XP_016883987 (OMIM: 604297,615530) PREDICTED: syna (1531) 626 120.9 4.8e-26
XP_016883985 (OMIM: 604297,615530) PREDICTED: syna (1544) 626 120.9 4.8e-26
XP_016883983 (OMIM: 604297,615530) PREDICTED: syna (1557) 626 120.9 4.8e-26
XP_016883988 (OMIM: 604297,615530) PREDICTED: syna (1565) 626 120.9 4.9e-26
XP_016883986 (OMIM: 604297,615530) PREDICTED: syna (1596) 626 120.9 4.9e-26
XP_016883984 (OMIM: 604297,615530) PREDICTED: syna (1607) 626 120.9 5e-26
NP_003886 (OMIM: 604297,615530) synaptojanin-1 iso (1612) 626 120.9 5e-26
XP_005267257 (OMIM: 609410) PREDICTED: synaptojani ( 909) 612 118.3 1.7e-25
XP_011543302 (OMIM: 258480,600829) PREDICTED: phos (1206) 563 109.9 7.9e-23
XP_011543301 (OMIM: 258480,600829) PREDICTED: phos (1258) 563 109.9 8.2e-23
NP_001558 (OMIM: 258480,600829) phosphatidylinosit (1258) 563 109.9 8.2e-23
XP_016873162 (OMIM: 258480,600829) PREDICTED: phos (1270) 563 109.9 8.2e-23
XP_005274036 (OMIM: 258480,600829) PREDICTED: phos (1280) 563 109.9 8.3e-23
>>NP_001305713 (OMIM: 300535,300555,309000) inositol pol (902 aa)
initn: 6123 init1: 6123 opt: 6123 Z-score: 5759.7 bits: 1077.0 E(85289): 0
Smith-Waterman score: 6123; 100.0% identity (100.0% similar) in 902 aa overlap (1-902:1-902)
10 20 30 40 50 60
pF1KB3 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
850 860 870 880 890 900
pF1KB3 ED
::
NP_001 ED
>>NP_000267 (OMIM: 300535,300555,309000) inositol polyph (901 aa)
initn: 6099 init1: 6020 opt: 6101 Z-score: 5739.1 bits: 1073.1 E(85289): 0
Smith-Waterman score: 6101; 99.9% identity (99.9% similar) in 902 aa overlap (1-902:1-901)
10 20 30 40 50 60
pF1KB3 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEPPLPVGAQPLA-TVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
840 850 860 870 880 890
pF1KB3 ED
::
NP_000 ED
900
>>NP_001578 (OMIM: 300535,300555,309000) inositol polyph (893 aa)
initn: 4789 init1: 4710 opt: 6025 Z-score: 5667.7 bits: 1059.9 E(85289): 0
Smith-Waterman score: 6025; 99.0% identity (99.0% similar) in 902 aa overlap (1-902:1-893)
10 20 30 40 50 60
pF1KB3 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPLPVGAQPLA-TVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_001 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLE--------KSLLQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSE
840 850 860 870 880 890
pF1KB3 ED
::
NP_001 ED
>>XP_011529646 (OMIM: 300535,300555,309000) PREDICTED: i (853 aa)
initn: 5579 init1: 5579 opt: 5579 Z-score: 5248.6 bits: 982.3 E(85289): 0
Smith-Waterman score: 5579; 100.0% identity (100.0% similar) in 821 aa overlap (82-902:33-853)
60 70 80 90 100 110
pF1KB3 HVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSA
::::::::::::::::::::::::::::::
XP_011 WRLLVNLKQFQRDPKLMAGDRVERKSYEPGGCKIRVQGDWIRERRFEIPDEEHCLKFLSA
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB3 VLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQP
70 80 90 100 110 120
180 190 200 210 220 230
pF1KB3 TGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKR
130 140 150 160 170 180
240 250 260 270 280 290
pF1KB3 EKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFE
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB3 SVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMG
250 260 270 280 290 300
360 370 380 390 400 410
pF1KB3 KMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB3 IMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGE
370 380 390 400 410 420
480 490 500 510 520 530
pF1KB3 IKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSAL
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB3 FHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQIS
490 500 510 520 530 540
600 610 620 630 640 650
pF1KB3 NNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGE
550 560 570 580 590 600
660 670 680 690 700 710
pF1KB3 DKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSF
610 620 630 640 650 660
720 730 740 750 760 770
pF1KB3 LEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIID
670 680 690 700 710 720
780 790 800 810 820 830
pF1KB3 CLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPR
730 740 750 760 770 780
840 850 860 870 880 890
pF1KB3 CHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQF
790 800 810 820 830 840
900
pF1KB3 LLGFLLGSEED
:::::::::::
XP_011 LLGFLLGSEED
850
>>XP_011529647 (OMIM: 300535,300555,309000) PREDICTED: i (853 aa)
initn: 5579 init1: 5579 opt: 5579 Z-score: 5248.6 bits: 982.3 E(85289): 0
Smith-Waterman score: 5579; 100.0% identity (100.0% similar) in 821 aa overlap (82-902:33-853)
60 70 80 90 100 110
pF1KB3 HVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSA
::::::::::::::::::::::::::::::
XP_011 WRLLVNLKQFQRDPKLMAGDRVERKSYEPGGCKIRVQGDWIRERRFEIPDEEHCLKFLSA
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB3 VLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQP
70 80 90 100 110 120
180 190 200 210 220 230
pF1KB3 TGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKR
130 140 150 160 170 180
240 250 260 270 280 290
pF1KB3 EKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFE
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB3 SVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMG
250 260 270 280 290 300
360 370 380 390 400 410
pF1KB3 KMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB3 IMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGE
370 380 390 400 410 420
480 490 500 510 520 530
pF1KB3 IKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSAL
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB3 FHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQIS
490 500 510 520 530 540
600 610 620 630 640 650
pF1KB3 NNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGE
550 560 570 580 590 600
660 670 680 690 700 710
pF1KB3 DKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSF
610 620 630 640 650 660
720 730 740 750 760 770
pF1KB3 LEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIID
670 680 690 700 710 720
780 790 800 810 820 830
pF1KB3 CLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPR
730 740 750 760 770 780
840 850 860 870 880 890
pF1KB3 CHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQF
790 800 810 820 830 840
900
pF1KB3 LLGFLLGSEED
:::::::::::
XP_011 LLGFLLGSEED
850
>>XP_016885043 (OMIM: 300535,300555,309000) PREDICTED: i (831 aa)
initn: 5289 init1: 5210 opt: 5292 Z-score: 4979.0 bits: 932.4 E(85289): 0
Smith-Waterman score: 5292; 97.3% identity (98.4% similar) in 804 aa overlap (1-804:1-803)
10 20 30 40 50 60
pF1KB3 MEPPLPVGAQPLAHTVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPPLPVGAQPLA-TVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPIN
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIW
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKY
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHF
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPET
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 IPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYL
: . .. . .. .: :..
XP_016 IRILCDQSLRSWMRTFDLFPYPALTKRKQGVDNNDLKAWDIEATALVLFSFR
780 790 800 810 820 830
>>XP_005262479 (OMIM: 300535,300555,309000) PREDICTED: i (744 aa)
initn: 5055 init1: 5055 opt: 5055 Z-score: 4756.9 bits: 891.1 E(85289): 0
Smith-Waterman score: 5055; 100.0% identity (100.0% similar) in 744 aa overlap (159-902:1-744)
130 140 150 160 170 180
pF1KB3 DSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPPPFSVNKM
::::::::::::::::::::::::::::::
XP_005 MNLDKKINSQNQPTGIHREPPPPPFSVNKM
10 20 30
190 200 210 220 230 240
pF1KB3 LPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTW
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB3 NVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHS
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB3 KAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNT
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB3 TFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRL
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB3 CMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWD
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB3 SSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVF
340 350 360 370 380 390
550 560 570 580 590 600
pF1KB3 EDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLND
400 410 420 430 440 450
610 620 630 640 650 660
pF1KB3 SQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDY
460 470 480 490 500 510
670 680 690 700 710 720
pF1KB3 FLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGA
520 530 540 550 560 570
730 740 750 760 770 780
pF1KB3 SERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSV
580 590 600 610 620 630
790 800 810 820 830 840
pF1KB3 AEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELL
640 650 660 670 680 690
850 860 870 880 890 900
pF1KB3 KFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED
700 710 720 730 740
>>NP_001284363 (OMIM: 147264) type II inositol 1,4,5-tri (749 aa)
initn: 2591 init1: 1570 opt: 2078 Z-score: 1958.1 bits: 373.3 E(85289): 2.5e-102
Smith-Waterman score: 2657; 51.1% identity (78.2% similar) in 751 aa overlap (147-896:16-745)
120 130 140 150 160 170
pF1KB3 KAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHR
:.. :.. : ... .:.. .:..: ...
NP_001 MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQP
10 20 30 40
180 190 200 210 220 230
pF1KB3 EPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYV
. .. :. : . . ... .. .:.:. : :. ..: : ..:..:.
NP_001 RQNKSKSEITDMV-RSSTITVSDKAHIL-SMQKF-------GLRDTIVKSHLLQKEEDYT
50 60 70 80 90
240 250 260 270 280 290
pF1KB3 NIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQ
::.::::.::.::::::: :. ::. . ::.::.:::::::: ::::. .. ::.
NP_001 YIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEE
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB3 EWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNK
:: :: .::: ::: ::.:.::::.:::....... :: .. .:::::::::.::::
NP_001 EWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNK
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB3 GGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHE
::::.:: ::::..:.::::::::.:..:::::::::::.::.: :. .:: :.: .:.
NP_001 GGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHD
220 230 240 250 260 270
420 430 440 450 460 470
pF1KB3 VVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIP
:..::::::::. :...::.::..::.: : .:::.:: . : .: :.:::. : :
NP_001 VILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQP
280 290 300 310 320 330
480 490 500 510 520 530
pF1KB3 TYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGV
:::::. .: ::.: :::.:::::::::.: :..::.:.::: ::::::::::..: :::
NP_001 TYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGV
340 350 360 370 380 390
540 550 560 570 580 590
pF1KB3 KVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQV
.::... :::..:. :: .:.::: .::. ::.::: :.:::. ::. :.: : .::::
NP_001 RVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQV
400 410 420 430 440 450
600 610 620 630 640 650
pF1KB3 PCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIED
:::: :: : .. .::: :: :.: .:.: :. :.:.:...:.: ..: ::::::::::
NP_001 PCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIED
460 470 480 490 500 510
660 670 680 690 700 710
pF1KB3 ILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEK
::::::::::::::..::::::::::. ...:: :..:: ..:. . .:
NP_001 ILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLETISEL----------
520 530 540 550 560
720 730 740 750 760 770
pF1KB3 SLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDT
.:. . :.:.. . :...:::.:..::.:.. : .:::::: ::.. :...: :::::
NP_001 TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDT
570 580 590 600 610 620
780 790 800 810 820 830
pF1KB3 SIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRN
.. ... .::::::::::.:::.:::::::: :. ::. . . .:::: :: :.:
NP_001 GMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVISTLPIFHKN
630 640 650 660 670 680
840 850 860 870 880 890
pF1KB3 VFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGF
::.::::::::::: : : .. :..:..: ::::: : . . .....: .:. :
NP_001 VFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAG-HQKLDMTEKKKAQEFIHQF
690 700 710 720 730 740
900
pF1KB3 LLGSEED
:
NP_001 LCNPL
>>XP_016856696 (OMIM: 147264) PREDICTED: type II inosito (794 aa)
initn: 2591 init1: 1570 opt: 2078 Z-score: 1957.7 bits: 373.3 E(85289): 2.6e-102
Smith-Waterman score: 2657; 51.1% identity (78.2% similar) in 751 aa overlap (147-896:61-790)
120 130 140 150 160 170
pF1KB3 KAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHR
:.. :.. : ... .:.. .:..: ...
XP_016 AELELEMPTPRGCNSALVTWPGYATIGGGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQP
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB3 EPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYV
. .. :. : . . ... .. .:.:. : :. ..: : ..:..:.
XP_016 RQNKSKSEITDMV-RSSTITVSDKAHIL-SMQKF-------GLRDTIVKSHLLQKEEDYT
100 110 120 130 140
240 250 260 270 280 290
pF1KB3 NIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQ
::.::::.::.::::::: :. ::. . ::.::.:::::::: ::::. .. ::.
XP_016 YIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEE
150 160 170 180 190 200
300 310 320 330 340 350
pF1KB3 EWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNK
:: :: .::: ::: ::.:.::::.:::....... :: .. .:::::::::.::::
XP_016 EWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNK
210 220 230 240 250 260
360 370 380 390 400 410
pF1KB3 GGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHE
::::.:: ::::..:.::::::::.:..:::::::::::.::.: :. .:: :.: .:.
XP_016 GGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHD
270 280 290 300 310 320
420 430 440 450 460 470
pF1KB3 VVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIP
:..::::::::. :...::.::..::.: : .:::.:: . : .: :.:::. : :
XP_016 VILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQP
330 340 350 360 370 380
480 490 500 510 520 530
pF1KB3 TYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGV
:::::. .: ::.: :::.:::::::::.: :..::.:.::: ::::::::::..: :::
XP_016 TYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGV
390 400 410 420 430 440
540 550 560 570 580 590
pF1KB3 KVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQV
.::... :::..:. :: .:.::: .::. ::.::: :.:::. ::. :.: : .::::
XP_016 RVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQV
450 460 470 480 490 500
600 610 620 630 640 650
pF1KB3 PCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIED
:::: :: : .. .::: :: :.: .:.: :. :.:.:...:.: ..: ::::::::::
XP_016 PCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIED
510 520 530 540 550 560
660 670 680 690 700 710
pF1KB3 ILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEK
::::::::::::::..::::::::::. ...:: :..:: ..:. . .:
XP_016 ILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLETISEL----------
570 580 590 600 610
720 730 740 750 760 770
pF1KB3 SLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDT
.:. . :.:.. . :...:::.:..::.:.. : .:::::: ::.. :...: :::::
XP_016 TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDT
620 630 640 650 660 670
780 790 800 810 820 830
pF1KB3 SIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRN
.. ... .::::::::::.:::.:::::::: :. ::. . . .:::: :: :.:
XP_016 GMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVISTLPIFHKN
680 690 700 710 720 730
840 850 860 870 880 890
pF1KB3 VFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGF
::.::::::::::: : : .. :..:..: ::::: : . . .....: .:. :
XP_016 VFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAG-HQKLDMTEKKKAQEFIHQF
740 750 760 770 780
900
pF1KB3 LLGSEED
:
XP_016 LCNPL
790
>>XP_016856695 (OMIM: 147264) PREDICTED: type II inosito (823 aa)
initn: 2129 init1: 1547 opt: 2078 Z-score: 1957.5 bits: 373.3 E(85289): 2.7e-102
Smith-Waterman score: 2174; 51.0% identity (78.6% similar) in 608 aa overlap (147-753:180-767)
120 130 140 150 160 170
pF1KB3 KAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHR
:.. :.. : ... .:.. .:..: ...
XP_016 AELELEMPTPRGCNSALVTWPGYATIGGGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQP
150 160 170 180 190 200
180 190 200 210 220 230
pF1KB3 EPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYV
. .. :. : . . ... .. .:.:. : :. ..: : ..:..:.
XP_016 RQNKSKSEITDMV-RSSTITVSDKAHIL-SMQKF-------GLRDTIVKSHLLQKEEDYT
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB3 NIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQ
::.::::.::.::::::: :. ::. . ::.::.:::::::: ::::. .. ::.
XP_016 YIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEE
270 280 290 300 310 320
300 310 320 330 340 350
pF1KB3 EWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNK
:: :: .::: ::: ::.:.::::.:::....... :: .. .:::::::::.::::
XP_016 EWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNK
330 340 350 360 370 380
360 370 380 390 400 410
pF1KB3 GGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHE
::::.:: ::::..:.::::::::.:..:::::::::::.::.: :. .:: :.: .:.
XP_016 GGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHD
390 400 410 420 430 440
420 430 440 450 460 470
pF1KB3 VVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIP
:..::::::::. :...::.::..::.: : .:::.:: . : .: :.:::. : :
XP_016 VILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQP
450 460 470 480 490 500
480 490 500 510 520 530
pF1KB3 TYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGV
:::::. .: ::.: :::.:::::::::.: :..::.:.::: ::::::::::..: :::
XP_016 TYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGV
510 520 530 540 550 560
540 550 560 570 580 590
pF1KB3 KVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQV
.::... :::..:. :: .:.::: .::. ::.::: :.:::. ::. :.: : .::::
XP_016 RVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQV
570 580 590 600 610
600 610 620 630 640 650
pF1KB3 PCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIED
:::: :: : .. .::: :: :.: .:.: :. :.:.:...:.: ..: ::::::::::
XP_016 PCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIED
620 630 640 650 660 670
660 670 680 690 700 710
pF1KB3 ILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEK
::::::::::::::..::::::::::. ...:: :..:: ..:. . .:
XP_016 ILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLETISEL----------
680 690 700 710 720
720 730 740 750 760 770
pF1KB3 SLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDT
.:. . :.:.. . :...:::.:..::.:.. : .:
XP_016 TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQFYNRCLKTYCRNMPGKACKMNS
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB3 SIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRN
XP_016 PHQPKSDHLSGDSEASPHCSFLHSAIDIARSGNH
790 800 810 820
902 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:04:59 2016 done: Thu Nov 3 21:05:01 2016
Total Scan time: 13.490 Total Display time: 0.280
Function used was FASTA [36.3.4 Apr, 2011]