Result of FASTA (omim) for
pFN21AB5448
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5448, 193 aa
1>>>pF1KB5448 193 - 193 aa - 193 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2647+/-0.000358; mu= 13.7504+/- 0.023
mean_var=78.9158+/-15.666, 0's: 0 Z-trim(115.9): 399 B-trim: 597 in 1/53
Lambda= 0.144375
statistics sampled from 26247 (26731) to 26247 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.313), width: 16
Scan time: 5.930
The best scores are: opt bits E(85289)
NP_001300870 (OMIM: 165390) transforming protein R ( 193) 1306 281.1 7.7e-76
NP_001655 (OMIM: 165390) transforming protein RhoA ( 193) 1306 281.1 7.7e-76
NP_001036143 (OMIM: 165380) rho-related GTP-bindin ( 193) 1222 263.6 1.4e-70
NP_786886 (OMIM: 165380) rho-related GTP-binding p ( 193) 1222 263.6 1.4e-70
NP_001036144 (OMIM: 165380) rho-related GTP-bindin ( 193) 1222 263.6 1.4e-70
NP_004031 (OMIM: 165370) rho-related GTP-binding p ( 196) 1122 242.8 2.7e-64
NP_001300872 (OMIM: 165390) transforming protein R ( 187) 944 205.7 3.8e-53
NP_001300873 (OMIM: 165390) transforming protein R ( 173) 889 194.2 1e-49
NP_001300874 (OMIM: 165390) transforming protein R ( 112) 766 168.4 3.7e-42
NP_008839 (OMIM: 602048) ras-related C3 botulinum ( 192) 735 162.1 4.9e-40
NP_001656 (OMIM: 179505) rho-related GTP-binding p ( 191) 724 159.9 2.4e-39
XP_016873208 (OMIM: 179505) PREDICTED: rho-related ( 191) 724 159.9 2.4e-39
XP_005252973 (OMIM: 179505) PREDICTED: rho-related ( 191) 724 159.9 2.4e-39
NP_001782 (OMIM: 116952,616737) cell division cont ( 191) 705 155.9 3.7e-38
NP_001034891 (OMIM: 116952,616737) cell division c ( 191) 705 155.9 3.7e-38
NP_005043 (OMIM: 602050) ras-related C3 botulinum ( 192) 704 155.7 4.3e-38
NP_002863 (OMIM: 602049,608203) ras-related C3 bot ( 192) 700 154.9 7.6e-38
NP_426359 (OMIM: 116952,616737) cell division cont ( 191) 696 154.0 1.4e-37
NP_055393 (OMIM: 605781) rho-related GTP-binding p ( 210) 682 151.1 1.1e-36
NP_036381 (OMIM: 605857) rho-related GTP-binding p ( 205) 679 150.5 1.7e-36
NP_001241667 (OMIM: 602924) rho-related GTP-bindin ( 244) 661 146.8 2.6e-35
NP_005159 (OMIM: 602924) rho-related GTP-binding p ( 244) 661 146.8 2.6e-35
NP_005431 (OMIM: 601555) rho-related GTP-binding p ( 227) 650 144.5 1.2e-34
XP_011523618 (OMIM: 601555) PREDICTED: rho-related ( 234) 650 144.5 1.2e-34
NP_065714 (OMIM: 607653) rho-related GTP-binding p ( 214) 641 142.6 4.2e-34
NP_001303236 (OMIM: 602050) ras-related C3 botulin ( 170) 619 137.9 8.4e-33
XP_006724349 (OMIM: 602049,608203) PREDICTED: ras- ( 161) 604 134.8 7e-32
XP_016859205 (OMIM: 605857) PREDICTED: rho-related ( 172) 591 132.1 4.8e-31
NP_067028 (OMIM: 606366) rho-related GTP-binding p ( 258) 593 132.7 4.9e-31
XP_011531028 (OMIM: 605857) PREDICTED: rho-related ( 192) 590 131.9 6e-31
NP_055285 (OMIM: 609038) rho-related GTP-binding p ( 232) 550 123.7 2.2e-28
XP_006720277 (OMIM: 607653) PREDICTED: rho-related ( 176) 547 123.0 2.8e-28
XP_011523619 (OMIM: 601555) PREDICTED: rho-related ( 206) 535 120.5 1.8e-27
NP_001265296 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
XP_016863677 (OMIM: 602037) PREDICTED: rho-related ( 191) 512 115.7 4.7e-26
NP_001265289 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_001265294 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
XP_011511994 (OMIM: 602037) PREDICTED: rho-related ( 191) 512 115.7 4.7e-26
XP_016863678 (OMIM: 602037) PREDICTED: rho-related ( 191) 512 115.7 4.7e-26
NP_001265298 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_001265293 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_001265290 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_001265291 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_001265292 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_001265297 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_001265295 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_001265288 (OMIM: 602037) rho-related GTP-bindin ( 191) 512 115.7 4.7e-26
NP_004301 (OMIM: 602037) rho-related GTP-binding p ( 191) 512 115.7 4.7e-26
XP_011531030 (OMIM: 605857) PREDICTED: rho-related ( 157) 445 101.7 6.4e-22
NP_001300875 (OMIM: 165390) transforming protein R ( 109) 391 90.3 1.2e-18
>>NP_001300870 (OMIM: 165390) transforming protein RhoA (193 aa)
initn: 1306 init1: 1306 opt: 1306 Z-score: 1482.5 bits: 281.1 E(85289): 7.7e-76
Smith-Waterman score: 1306; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
130 140 150 160 170 180
190
pF1KB5 ARRGKKKSGCLVL
:::::::::::::
NP_001 ARRGKKKSGCLVL
190
>>NP_001655 (OMIM: 165390) transforming protein RhoA iso (193 aa)
initn: 1306 init1: 1306 opt: 1306 Z-score: 1482.5 bits: 281.1 E(85289): 7.7e-76
Smith-Waterman score: 1306; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
130 140 150 160 170 180
190
pF1KB5 ARRGKKKSGCLVL
:::::::::::::
NP_001 ARRGKKKSGCLVL
190
>>NP_001036143 (OMIM: 165380) rho-related GTP-binding pr (193 aa)
initn: 1222 init1: 1222 opt: 1222 Z-score: 1388.0 bits: 263.6 E(85289): 1.4e-70
Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_001 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB5 ARRGKKKSGCLVL
.:..:.. :: .:
NP_001 VRKNKRRRGCPIL
190
>>NP_786886 (OMIM: 165380) rho-related GTP-binding prote (193 aa)
initn: 1222 init1: 1222 opt: 1222 Z-score: 1388.0 bits: 263.6 E(85289): 1.4e-70
Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_786 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_786 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB5 ARRGKKKSGCLVL
.:..:.. :: .:
NP_786 VRKNKRRRGCPIL
190
>>NP_001036144 (OMIM: 165380) rho-related GTP-binding pr (193 aa)
initn: 1222 init1: 1222 opt: 1222 Z-score: 1388.0 bits: 263.6 E(85289): 1.4e-70
Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_001 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
130 140 150 160 170 180
190
pF1KB5 ARRGKKKSGCLVL
.:..:.. :: .:
NP_001 VRKNKRRRGCPIL
190
>>NP_004031 (OMIM: 165370) rho-related GTP-binding prote (196 aa)
initn: 1130 init1: 1110 opt: 1122 Z-score: 1275.3 bits: 242.8 E(85289): 2.7e-64
Smith-Waterman score: 1122; 85.3% identity (94.8% similar) in 191 aa overlap (1-191:1-190)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::.::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_004 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
:::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_004 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
::.:::.: :::.::::::. ..:: :: :: :. :.:::::::.::::::: :::::::
NP_004 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
130 140 150 160 170 180
190
pF1KB5 ARRGKKKSGCLVL
: :.. .::.
NP_004 KRYGSQ-NGCINCCKVL
190
>>NP_001300872 (OMIM: 165390) transforming protein RhoA (187 aa)
initn: 944 init1: 944 opt: 944 Z-score: 1075.2 bits: 205.7 E(85289): 3.8e-53
Smith-Waterman score: 944; 100.0% identity (100.0% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
::::::::::::::::::
NP_001 LRNDEHTRRELAKMKQEPHCVARLECCGTILAQLQPPPPRFKRFPCLSLLSSWGYRRPLP
130 140 150 160 170 180
>>NP_001300873 (OMIM: 165390) transforming protein RhoA (173 aa)
initn: 889 init1: 889 opt: 889 Z-score: 1013.8 bits: 194.2 E(85289): 1e-49
Smith-Waterman score: 1124; 89.6% identity (89.6% similar) in 193 aa overlap (1-193:1-173)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
:::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYV-----------------
10 20 30 40
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
110 120 130 140 150 160
190
pF1KB5 ARRGKKKSGCLVL
:::::::::::::
NP_001 ARRGKKKSGCLVL
170
>>NP_001300874 (OMIM: 165390) transforming protein RhoA (112 aa)
initn: 766 init1: 766 opt: 766 Z-score: 877.9 bits: 168.4 E(85289): 3.7e-42
Smith-Waterman score: 766; 100.0% identity (100.0% similar) in 112 aa overlap (82-193:1-112)
60 70 80 90 100 110
pF1KB5 QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVP
::::::::::::::::::::::::::::::
NP_001 MCFSIDSPDSLENIPEKWTPEVKHFCPNVP
10 20 30
120 130 140 150 160 170
pF1KB5 IILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVF
40 50 60 70 80 90
180 190
pF1KB5 EMATRAALQARRGKKKSGCLVL
::::::::::::::::::::::
NP_001 EMATRAALQARRGKKKSGCLVL
100 110
>>NP_008839 (OMIM: 602048) ras-related C3 botulinum toxi (192 aa)
initn: 719 init1: 719 opt: 735 Z-score: 839.8 bits: 162.1 E(85289): 4.9e-40
Smith-Waterman score: 735; 57.7% identity (76.3% similar) in 194 aa overlap (1-193:1-192)
10 20 30 40 50 60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
: :: : :.::::: ::::::: .. . :: :.::::.:: :.. :::: :.:.::::
NP_008 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
:::::::::::::::.:::.:.:::. :: :.::. :: :::.: :::.::::::.: :
NP_008 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLD
60 70 80 90 100 110
130 140 150 160 170
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL-
::.:. : ..: . : :. .: ::..::: :.:::: :. :.. ::. : ::.:
NP_008 LRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC
120 130 140 150 160 170
180 190
pF1KB5 QARRGKKKSGCLVL
:.: ::.:
NP_008 PPPVKKRKRKCLLL
180 190
193 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:24:30 2016 done: Thu Nov 3 17:24:32 2016
Total Scan time: 5.930 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]