Result of FASTA (ccds) for
pFN21AB5053
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5053, 780 aa
1>>>pF1KB5053 780 - 780 aa - 780 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6481+/-0.000993; mu= 18.4132+/- 0.060
mean_var=67.5270+/-13.665, 0's: 0 Z-trim(104.5): 39 B-trim: 315 in 2/49
Lambda= 0.156076
statistics sampled from 7914 (7934) to 7914 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.244), width: 16
Scan time: 3.620
The best scores are: opt bits E(32554)
CCDS14017.1 ACO2 gene_id:50|Hs108|chr22 ( 780) 5255 1192.7 0
CCDS6525.1 ACO1 gene_id:48|Hs108|chr9 ( 889) 352 88.8 4.3e-17
CCDS10302.1 IREB2 gene_id:3658|Hs108|chr15 ( 963) 325 82.7 3.1e-15
>>CCDS14017.1 ACO2 gene_id:50|Hs108|chr22 (780 aa)
initn: 5255 init1: 5255 opt: 5255 Z-score: 6387.7 bits: 1192.7 E(32554): 0
Smith-Waterman score: 5255; 100.0% identity (100.0% similar) in 780 aa overlap (1-780:1-780)
10 20 30 40 50 60
pF1KB5 MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 RPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 PSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILEN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 YAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 WSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 WSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 HRMKKYLSKTGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 HRMKKYLSKTGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 EQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 DANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 QDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 QDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 GPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 GDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 VDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
730 740 750 760 770 780
>>CCDS6525.1 ACO1 gene_id:48|Hs108|chr9 (889 aa)
initn: 689 init1: 303 opt: 352 Z-score: 420.3 bits: 88.8 E(32554): 4.3e-17
Smith-Waterman score: 737; 28.5% identity (54.4% similar) in 744 aa overlap (91-709:78-818)
70 80 90 100 110
pF1KB5 RPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF--ISSGLSKV
..: :: .:: :. :...: . ....:.
CCDS65 RNCDEFLVKKQDIENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKL
50 60 70 80 90 100
120 130 140 150 160
pF1KB5 A---------VPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAG-AKYGV
. :. . :: :... . . : :.. .:. :.: ..:: .. : ...
CCDS65 GGDPEKINPVCPADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNM
110 120 130 140 150 160
170 180 190 200 210
pF1KB5 GFWKPGSGIIHQIILE----------NYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADA
. ::::::::. :: .: :: : .:::::: ::: . :::: .:
CCDS65 RIIPPGSGIIHQVNLEYLARVVFDQDGYYYPDSL-VGTDSHTTMIDGLGILGWGVGGIEA
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB5 VDVMAGIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVD
:: : : . :.::: .: :. . :..: .. : : .: .::. ::::
CCDS65 EAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVA
230 240 250 260 270 280
280 290 300 310 320
pF1KB5 SISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRED--------IANLADEFKDH
..: . ::: :: : :::.. :: .. :: .:::.. . . :.:
CCDS65 QLSIADRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDF
290 300 310 320 330 340
330 340 350 360 370
pF1KB5 LVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGK-----VAEKEGW------P
:. . :..:..:. . : .:: :. :... : .. :.:. :
CCDS65 NDPSQDPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAP
350 360 370 380 390 400
380 390 400 410
pF1KB5 ----------LD----------IRVGLIGSCTNSSYEDMGRSAAV-AKQALAHGLKCKS-
: . .. : ::::.: .. .:.. ::.:. ::.
CCDS65 EHHNDHKTFIYDNTEFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPY
410 420 430 440 450 460
420 430 440 450 460
pF1KB5 -QFTITPGSEQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDR------KDIKKGEK
. ...::: . ....: : .:: :.. .: :::. . : .:.
CCDS65 IKTSLSPGSGVVTYYLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDL
470 480 490 500 510 520
470 480 490 500 510 520
pF1KB5 NTI-VTSYNRNFTGRNDANPETHA-FVTSPEIVTALAIAGTLKFNPETDYL-TGTDGKKF
.. : : :::: :: ..:.:.: ...:: .: : :::::.... : . : ... :..
CCDS65 VAVGVLSGNRNFEGR--VHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQV
530 540 550 560 570 580
530 540 550 560
pF1KB5 RLEA--PDADELPKGEFD---PG--QDTYQHPPKDSSGQHVDVSPT-------SQRLQLL
:. : ::. : . :: ...::. . . .. ..:. :. .
CCDS65 FLKDIWPTRDEIQAVERQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIK
590 600 610 620 630 640
570 580 590 600
pF1KB5 EP-------FDKWDGKDLEDLQILIKVKGKCTTDHISAAG------PWLKF---RG----
: .: :.. : .:... . :::::: :: : .. ::
CCDS65 SPPFFENLTLDLQPPKSIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPR
650 660 670 680 690 700
610 620 630 640 650
pF1KB5 HLDNISNNLLIGAI-------NIE------NGKANSVRNAVTQEFGPVPDTARYYKKHGI
.... .. :. ::. : .: .. . . :. : :.:. :.. :.
CCDS65 EFNSYGSRRGNDAVMARGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGL
710 720 730 740 750 760
660 670 680 690 700 710
pF1KB5 RWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADY
.:.. ..:: ::::. :: : :: .:....:. :::..:: .:..:: .
CCDS65 PLIVLAGKEYGAGSSRDWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENA
770 780 790 800 810 820
720 730 740 750 760 770
pF1KB5 NKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRM
CCDS65 DALGLTGQERYTIIIPENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMI
830 840 850 860 870 880
>>CCDS10302.1 IREB2 gene_id:3658|Hs108|chr15 (963 aa)
initn: 571 init1: 283 opt: 325 Z-score: 386.9 bits: 82.7 E(32554): 3.1e-15
Smith-Waterman score: 598; 28.3% identity (52.1% similar) in 674 aa overlap (147-709:225-893)
120 130 140 150 160 170
pF1KB5 KVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKY-GVGFWKPGSGIIHQ
:.: .:. .. . .:. ::.:. ::
CCDS10 ENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQ
200 210 220 230 240 250
180 190 200 210 220
pF1KB5 IILE----------NYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELK
: :: . .: . .::::: .::: . :::: .. :: :.: :
CCDS10 INLEYLSRVVFEEKDLLFPDSV-VGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLT
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB5 CPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICN
:.:.: .:::: . . . ::.: .. : : .: .::. : ::...: . .:: :
CCDS10 LPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIAN
320 330 340 350 360 370
290 300 310 320 330
pF1KB5 MGAEIGATTSVFPYNHRMKKYLSKTG--------REDIANLADEFKDHLVPDPGCHYDQL
: : :: : :: .. :.: .:: : . . :.. . .:.:.
CCDS10 MCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQV
380 390 400 410 420 430
340 350 360 370
pF1KB5 IEINLSELKPHINGPFTP-----------DLAHPVAE-VG-----KVAEK---------E
:.:::. . : ..:: : :. . : :: .::: :
CCDS10 IQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQKDIVSIHYE
440 450 460 470 480 490
380 390 400 410 420
pF1KB5 G--WPLD---IRVGLIGSCTNSSYEDMGRSAAV-AKQALAHGLKCKSQF--TITPGSEQI
: . :. . .. . ::::. .. .:.. ::.:. ::. : . ...::: ..
CCDS10 GSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTSLSPGSGMV
500 510 520 530 540 550
430 440 450 460 470
pF1KB5 RATIERDGYAQILRDLGGIVLANACGPCIGQW-DRKD-----IKKGEKNTI-VTSYNRNF
. .: : :: ... .:. :.:. .: .:.:. : . : :.::
CCDS10 THYLSSSGVLPYLSKLGFEIVGYGCSICVGNTAPLSDAVLNAVKQGDLVTCGILSGNKNF
560 570 580 590 600 610
480 490 500 510 520 530
pF1KB5 TGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTD--GKKFRLEA--PDADEL
:: . ...:: .:.: :::::.... .:. : ::: ::.. :. :. .:.
CCDS10 EGRL-CDCVRANYLASPPLVVAYAIAGTVNIDFQTEPL-GTDPTGKNIYLHDIWPSREEV
620 630 640 650 660 670
540 550 560 570
pF1KB5 PKGE--------FDPGQDTYQHPPK--------DSSGQHVDVSPTSQRLQLLEPFDKWDG
. : : .: . : :: :.. : : . :::
CCDS10 HRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSF--FDKLTK
680 690 700 710 720
580 590 600 610 620
pF1KB5 KDL-----EDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLL----IGAINIENG
. . :. ..:. . . :::::: :: . . ..: : ... . . :
CCDS10 EPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRG
730 740 750 760 770 780
630 640 650 660
pF1KB5 K-ANSVRN--AVTQEFG-----PVPDT--------------ARYYKKHGIRWVVIGDENY
. : .:. : . :. :.: : :. :.:.:: .... ..:
CCDS10 NDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKY
790 800 810 820 830 840
670 680 690 700 710 720
pF1KB5 GEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLT
: :.::. :: : :: .:....:. .::. .: :. :: :
CCDS10 GSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRET
850 860 870 880 890 900
730 740 750 760 770 780
pF1KB5 IQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
CCDS10 FSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARKFS
910 920 930 940 950 960
780 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:50:09 2016 done: Thu Nov 3 15:50:10 2016
Total Scan time: 3.620 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]