Result of FASTA (omim) for
pFN21AB4394
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4394, 834 aa
1>>>pF1KB4394 834 - 834 aa - 834 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9167+/-0.000348; mu= 6.7750+/- 0.022
mean_var=226.7597+/-47.063, 0's: 0 Z-trim(122.2): 39 B-trim: 1953 in 1/57
Lambda= 0.085171
statistics sampled from 39839 (39894) to 39839 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.468), width: 16
Scan time: 11.510
The best scores are: opt bits E(85289)
NP_150252 (OMIM: 102578) protein PML isoform 10 [H ( 585) 3897 491.9 3.6e-138
NP_150253 (OMIM: 102578) protein PML isoform 11 [H ( 781) 3587 453.9 1.3e-126
NP_150249 (OMIM: 102578) protein PML isoform 7 [Ho ( 423) 2896 368.7 3e-101
NP_150250 (OMIM: 102578) protein PML isoform 8 [Ho ( 435) 2896 368.8 3e-101
NP_150247 (OMIM: 102578) protein PML isoform 5 [Ho ( 560) 2896 368.8 3.7e-101
NP_150243 (OMIM: 102578) protein PML isoform 2 [Ho ( 611) 2896 368.9 3.9e-101
NP_002666 (OMIM: 102578) protein PML isoform 6 [Ho ( 633) 2896 368.9 4e-101
NP_150242 (OMIM: 102578) protein PML isoform 9 [Ho ( 829) 2896 369.0 5e-101
NP_150241 (OMIM: 102578) protein PML isoform 1 [Ho ( 882) 2896 369.0 5.2e-101
>>NP_150252 (OMIM: 102578) protein PML isoform 10 [Homo (585 aa)
initn: 3931 init1: 3897 opt: 3897 Z-score: 2601.6 bits: 491.9 E(85289): 3.6e-138
Smith-Waterman score: 3897; 99.8% identity (100.0% similar) in 573 aa overlap (1-573:1-573)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 GPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSI
::::::::::::::::::::::::::::::::.
NP_150 GPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI
550 560 570 580
610 620 630 640 650 660
pF1KB4 YSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFL
>>NP_150253 (OMIM: 102578) protein PML isoform 11 [Homo (781 aa)
initn: 3587 init1: 3587 opt: 3587 Z-score: 2394.0 bits: 453.9 E(85289): 1.3e-126
Smith-Waterman score: 3587; 97.9% identity (98.9% similar) in 535 aa overlap (1-535:1-535)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLE
:::::::::::::::::::::::::::::::::::::::::: . .. . .::
NP_150 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 GPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSI
NP_150 PAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQER
550 560 570 580 590 600
>>NP_150249 (OMIM: 102578) protein PML isoform 7 [Homo s (423 aa)
initn: 2896 init1: 2896 opt: 2896 Z-score: 1938.8 bits: 368.7 E(85289): 3e-101
Smith-Waterman score: 2896; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLRN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
NP_150 ALW
>>NP_150250 (OMIM: 102578) protein PML isoform 8 [Homo s (435 aa)
initn: 2896 init1: 2896 opt: 2896 Z-score: 1938.6 bits: 368.8 E(85289): 3e-101
Smith-Waterman score: 2896; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
NP_150 PPAHALTGPAQSSTH
430
>>NP_150247 (OMIM: 102578) protein PML isoform 5 [Homo s (560 aa)
initn: 3458 init1: 2896 opt: 2896 Z-score: 1937.1 bits: 368.8 E(85289): 3.7e-101
Smith-Waterman score: 3367; 91.0% identity (91.2% similar) in 556 aa overlap (1-507:1-556)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE
370 380 390 400 410 420
420 430
pF1KB4 ----------------------------------------------DVSNTTTAQKRKCS
::::::::::::::
NP_150 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS
430 440 450 460 470 480
440 450 460 470 480 490
pF1KB4 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB4 NSNHVASGAGEA-EERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDEN
:::::::::::: .::
NP_150 NSNHVASGAGEAGRERNALW
550 560
>>NP_150243 (OMIM: 102578) protein PML isoform 2 [Homo s (611 aa)
initn: 3565 init1: 2896 opt: 2896 Z-score: 1936.6 bits: 368.9 E(85289): 3.9e-101
Smith-Waterman score: 3479; 88.4% identity (89.9% similar) in 596 aa overlap (1-547:1-596)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE
370 380 390 400 410 420
420 430
pF1KB4 ----------------------------------------------DVSNTTTAQKRKCS
::::::::::::::
NP_150 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS
430 440 450 460 470 480
440 450 460 470 480 490
pF1KB4 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB4 NSNHVASGAGEAEERVVVISSSEDSDAENS-SSRELDDSSSESSDLQLEGPSTLRVLDEN
:::::::::::::::::::::::::::::: :. :.. . : .. .: . .:
NP_150 NSNHVASGAGEAEERVVVISSSEDSDAENSVSGPEVQPRTPASPHFRSQGAQPQQVTLRL
550 560 570 580 590 600
560 570 580 590 600 610
pF1KB4 LADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGL
NP_150 ALRLGNFPVRH
610
>>NP_002666 (OMIM: 102578) protein PML isoform 6 [Homo s (633 aa)
initn: 3883 init1: 2896 opt: 2896 Z-score: 1936.4 bits: 368.9 E(85289): 4e-101
Smith-Waterman score: 3791; 92.1% identity (92.3% similar) in 621 aa overlap (1-573:1-621)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE
370 380 390 400 410 420
420 430
pF1KB4 ----------------------------------------------DVSNTTTAQKRKCS
::::::::::::::
NP_002 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS
430 440 450 460 470 480
440 450 460 470 480 490
pF1KB4 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB4 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL
550 560 570 580 590 600
560 570 580 590 600 610
pF1KB4 ADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQ
::::::::::::::::::::.
NP_002 ADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI
610 620 630
>>NP_150242 (OMIM: 102578) protein PML isoform 9 [Homo s (829 aa)
initn: 3573 init1: 2896 opt: 2896 Z-score: 1934.8 bits: 369.0 E(85289): 5e-101
Smith-Waterman score: 3481; 89.9% identity (90.7% similar) in 583 aa overlap (1-535:1-583)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE
370 380 390 400 410 420
420 430
pF1KB4 ----------------------------------------------DVSNTTTAQKRKCS
::::::::::::::
NP_150 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS
430 440 450 460 470 480
440 450 460 470 480 490
pF1KB4 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB4 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL
:::::::::::::::::::::::::::::: . .. . .::
NP_150 NSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPV
550 560 570 580 590 600
560 570 580 590 600 610
pF1KB4 ADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQ
NP_150 QSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLY
610 620 630 640 650 660
>>NP_150241 (OMIM: 102578) protein PML isoform 1 [Homo s (882 aa)
initn: 5575 init1: 2896 opt: 2896 Z-score: 1934.4 bits: 369.0 E(85289): 5.2e-101
Smith-Waterman score: 5383; 94.5% identity (94.5% similar) in 866 aa overlap (1-818:1-866)
10 20 30 40 50 60
pF1KB4 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE
370 380 390 400 410 420
420 430
pF1KB4 ----------------------------------------------DVSNTTTAQKRKCS
::::::::::::::
NP_150 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS
430 440 450 460 470 480
440 450 460 470 480 490
pF1KB4 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB4 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENL
550 560 570 580 590 600
560 570 580 590 600 610
pF1KB4 ADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 ADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQ
610 620 630 640 650 660
620 630 640 650 660 670
pF1KB4 HFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 HFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPG
670 680 690 700 710 720
680 690 700 710 720 730
pF1KB4 ASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 ASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFAS
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB4 LQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 LQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPA
790 800 810 820 830 840
800 810 820 830
pF1KB4 FNLQALGTYFEGLLEGPALARAEGVSTPLAGRGLAERASQQS
::::::::::::::::::::::::::
NP_150 FNLQALGTYFEGLLEGPALARAEGVSTPLAGRGLAERASQQS
850 860 870 880
834 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:56:39 2016 done: Thu Nov 3 14:56:41 2016
Total Scan time: 11.510 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]