Result of FASTA (omim) for
pFN21AB3935
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3935, 422 aa
1>>>pF1KB3935 422 - 422 aa - 422 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1493+/-0.000383; mu= 13.8315+/- 0.024
mean_var=115.8475+/-23.587, 0's: 0 Z-trim(116.5): 409 B-trim: 1513 in 2/55
Lambda= 0.119160
statistics sampled from 27222 (27753) to 27222 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.325), width: 16
Scan time: 7.880
The best scores are: opt bits E(85289)
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 2784 489.7 5.7e-138
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 2784 489.7 5.7e-138
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422) 2784 489.7 5.7e-138
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 2784 489.7 5.7e-138
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 2784 489.7 5.7e-138
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 2752 484.2 2.6e-136
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 2752 484.2 2.6e-136
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419) 2752 484.2 2.6e-136
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422) 2148 380.4 4.7e-105
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422) 2148 380.4 4.7e-105
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422) 2148 380.4 4.7e-105
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479) 2148 380.4 5.2e-105
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419) 2135 378.2 2.2e-104
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419) 2135 378.2 2.2e-104
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419) 2135 378.2 2.2e-104
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476) 2135 378.2 2.4e-104
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 1587 283.9 4.7e-76
XP_006723402 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 1587 283.9 4.7e-76
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 1587 283.9 4.7e-76
NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 ( 386) 1587 283.9 4.7e-76
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385) 1568 280.6 4.5e-75
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383) 1426 256.2 1e-67
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382) 1407 253.0 9.7e-67
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo ( 425) 987 180.8 5.7e-45
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425) 987 180.8 5.7e-45
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443) 987 180.8 5.9e-45
XP_006718799 (OMIM: 604146) PREDICTED: synaptotagm ( 293) 959 175.8 1.2e-43
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403) 959 176.0 1.5e-43
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409) 959 176.0 1.6e-43
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447) 959 176.0 1.7e-43
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449) 959 176.0 1.7e-43
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453) 959 176.0 1.7e-43
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478) 959 176.0 1.7e-43
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484) 959 176.0 1.8e-43
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528) 959 176.1 1.9e-43
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611) 959 176.1 2.1e-43
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617) 959 176.1 2.1e-43
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642) 959 176.2 2.2e-43
XP_011543639 (OMIM: 604146) PREDICTED: synaptotagm ( 648) 959 176.2 2.2e-43
XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651) 959 176.2 2.2e-43
XP_005274440 (OMIM: 604146) PREDICTED: synaptotagm ( 686) 959 176.2 2.3e-43
XP_011543637 (OMIM: 604146) PREDICTED: synaptotagm ( 692) 959 176.2 2.3e-43
XP_011518204 (OMIM: 613528) PREDICTED: synaptotagm ( 535) 948 174.2 7e-43
XP_011518203 (OMIM: 613528) PREDICTED: synaptotagm ( 564) 948 174.2 7.3e-43
XP_011518202 (OMIM: 613528) PREDICTED: synaptotagm ( 567) 948 174.2 7.4e-43
NP_783860 (OMIM: 613528) synaptotagmin-9 [Homo sap ( 491) 947 174.0 7.5e-43
XP_011518206 (OMIM: 613528) PREDICTED: synaptotagm ( 492) 947 174.0 7.5e-43
XP_011525692 (OMIM: 600327) PREDICTED: synaptotagm ( 590) 938 172.5 2.5e-42
NP_001153800 (OMIM: 600327) synaptotagmin-3 [Homo ( 590) 938 172.5 2.5e-42
NP_001153801 (OMIM: 600327) synaptotagmin-3 [Homo ( 590) 938 172.5 2.5e-42
>>XP_016875398 (OMIM: 185605) PREDICTED: synaptotagmin-1 (422 aa)
initn: 2784 init1: 2784 opt: 2784 Z-score: 2597.9 bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
370 380 390 400 410 420
pF1KB3 KK
::
XP_016 KK
>>XP_011537012 (OMIM: 185605) PREDICTED: synaptotagmin-1 (422 aa)
initn: 2784 init1: 2784 opt: 2784 Z-score: 2597.9 bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
370 380 390 400 410 420
pF1KB3 KK
::
XP_011 KK
>>NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 [Ho (422 aa)
initn: 2784 init1: 2784 opt: 2784 Z-score: 2597.9 bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
370 380 390 400 410 420
pF1KB3 KK
::
NP_005 KK
>>NP_001129278 (OMIM: 185605) synaptotagmin-1 isoform 1 (422 aa)
initn: 2784 init1: 2784 opt: 2784 Z-score: 2597.9 bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
370 380 390 400 410 420
pF1KB3 KK
::
NP_001 KK
>>NP_001129277 (OMIM: 185605) synaptotagmin-1 isoform 1 (422 aa)
initn: 2784 init1: 2784 opt: 2784 Z-score: 2597.9 bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
370 380 390 400 410 420
pF1KB3 KK
::
NP_001 KK
>>XP_005269170 (OMIM: 185605) PREDICTED: synaptotagmin-1 (419 aa)
initn: 2037 init1: 2037 opt: 2752 Z-score: 2568.3 bits: 484.2 E(85289): 2.6e-136
Smith-Waterman score: 2752; 99.3% identity (99.3% similar) in 422 aa overlap (1-422:1-419)
10 20 30 40 50 60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ---
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
360 370 380 390 400 410
pF1KB3 KK
::
XP_005 KK
>>XP_006719639 (OMIM: 185605) PREDICTED: synaptotagmin-1 (419 aa)
initn: 2037 init1: 2037 opt: 2752 Z-score: 2568.3 bits: 484.2 E(85289): 2.6e-136
Smith-Waterman score: 2752; 99.3% identity (99.3% similar) in 422 aa overlap (1-422:1-419)
10 20 30 40 50 60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ---
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
360 370 380 390 400 410
pF1KB3 KK
::
XP_006 KK
>>NP_001278830 (OMIM: 185605) synaptotagmin-1 isoform 2 (419 aa)
initn: 2037 init1: 2037 opt: 2752 Z-score: 2568.3 bits: 484.2 E(85289): 2.6e-136
Smith-Waterman score: 2752; 99.3% identity (99.3% similar) in 422 aa overlap (1-422:1-419)
10 20 30 40 50 60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ---
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
360 370 380 390 400 410
pF1KB3 KK
::
NP_001 KK
>>XP_016855801 (OMIM: 600104,616040) PREDICTED: synaptot (422 aa)
initn: 2349 init1: 1677 opt: 2148 Z-score: 2007.0 bits: 380.4 E(85289): 4.7e-105
Smith-Waterman score: 2148; 77.1% identity (90.3% similar) in 424 aa overlap (2-422:4-422)
10 20 30 40 50
pF1KB3 MVSESHHEALAAPPVTTVAT-VLP-SNATEPASPGEGKEDAFSKLKEKFMNELHKIPL
. . ..: ..:: .::.. . : .:.:: .. ::..:: :.:::::..::..::::
XP_016 MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 PPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKD
:::::::::.:: ::.::::::::::: :::..:: : :: :::.::::.: :. .:
XP_016 PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG-GQLPQD
70 80 90 100 110
120 130 140 150 160 170
pF1KB3 QALKDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMG
:::::::::.:: : :: :: :.:::::.::::::: ::: ::..:::::::::::
XP_016 ----DDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF
::::::::::::::::::.:::::::::::.::: :::::::.::::::::::.::::::
XP_016 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL
:::::::: ::::::::.:. :::::::..:::: ::::::: ::::::::::::: ::
XP_016 SKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCIL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK
:::::::::::::::::::::::::::::::::::.::.:::::.:::::::.:::::::
XP_016 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQK
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 VQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVD
::::::::::::.:::.::::.::: :.::.::::::::::::::::::::.:. :::::
XP_016 VQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVD
360 370 380 390 400 410
420
pF1KB3 AMLAVKK
:.:. .:
XP_016 ALLGKNK
420
>>XP_011507494 (OMIM: 600104,616040) PREDICTED: synaptot (422 aa)
initn: 2349 init1: 1677 opt: 2148 Z-score: 2007.0 bits: 380.4 E(85289): 4.7e-105
Smith-Waterman score: 2148; 77.1% identity (90.3% similar) in 424 aa overlap (2-422:4-422)
10 20 30 40 50
pF1KB3 MVSESHHEALAAPPVTTVAT-VLP-SNATEPASPGEGKEDAFSKLKEKFMNELHKIPL
. . ..: ..:: .::.. . : .:.:: .. ::..:: :.:::::..::..::::
XP_011 MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 PPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKD
:::::::::.:: ::.::::::::::: :::..:: : :: :::.::::.: :. .:
XP_011 PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG-GQLPQD
70 80 90 100 110
120 130 140 150 160 170
pF1KB3 QALKDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMG
:::::::::.:: : :: :: :.:::::.::::::: ::: ::..:::::::::::
XP_011 ----DDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF
::::::::::::::::::.:::::::::::.::: :::::::.::::::::::.::::::
XP_011 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL
:::::::: ::::::::.:. :::::::..:::: ::::::: ::::::::::::: ::
XP_011 SKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCIL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK
:::::::::::::::::::::::::::::::::::.::.:::::.:::::::.:::::::
XP_011 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQK
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 VQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVD
::::::::::::.:::.::::.::: :.::.::::::::::::::::::::.:. :::::
XP_011 VQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVD
360 370 380 390 400 410
420
pF1KB3 AMLAVKK
:.:. .:
XP_011 ALLGKNK
420
422 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:10:50 2016 done: Thu Nov 3 14:10:51 2016
Total Scan time: 7.880 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]