Result of FASTA (omim) for
pFN21AB3471
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3471, 534 aa
1>>>pF1KB3471 534 - 534 aa - 534 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9191+/-0.0004; mu= 22.1699+/- 0.025
mean_var=91.7751+/-18.121, 0's: 0 Z-trim(113.4): 83 B-trim: 21 in 1/52
Lambda= 0.133879
statistics sampled from 22605 (22688) to 22605 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.266), width: 16
Scan time: 8.940
The best scores are: opt bits E(85289)
NP_001269373 (OMIM: 605888) EH domain-containing p ( 534) 3552 696.7 4.6e-200
XP_011543041 (OMIM: 605888) PREDICTED: EH domain-c ( 534) 3552 696.7 4.6e-200
NP_006786 (OMIM: 605888) EH domain-containing prot ( 534) 3552 696.7 4.6e-200
NP_001269374 (OMIM: 605888) EH domain-containing p ( 548) 3552 696.7 4.7e-200
NP_055415 (OMIM: 605891) EH domain-containing prot ( 535) 3188 626.4 6.8e-179
NP_644670 (OMIM: 605892) EH domain-containing prot ( 541) 2759 543.5 6e-154
NP_055416 (OMIM: 605890) EH domain-containing prot ( 543) 2608 514.3 3.6e-145
XP_016877589 (OMIM: 605892) PREDICTED: EH domain-c ( 453) 2348 464.0 4.2e-130
XP_011531108 (OMIM: 605891) PREDICTED: EH domain-c ( 322) 1875 372.5 1.1e-102
NP_001310597 (OMIM: 604992) sarcalumenin isoform 2 ( 431) 765 158.3 4.5e-38
NP_001310596 (OMIM: 604992) sarcalumenin isoform 2 ( 431) 765 158.3 4.5e-38
XP_016879018 (OMIM: 604992) PREDICTED: sarcalumeni ( 431) 765 158.3 4.5e-38
XP_016879017 (OMIM: 604992) PREDICTED: sarcalumeni ( 431) 765 158.3 4.5e-38
NP_001092284 (OMIM: 604992) sarcalumenin isoform 1 ( 473) 765 158.3 4.7e-38
XP_016879016 (OMIM: 604992) PREDICTED: sarcalumeni ( 857) 765 158.6 7e-38
XP_016856106 (OMIM: 600051) PREDICTED: epidermal g ( 828) 344 77.3 2.1e-13
XP_016856105 (OMIM: 600051) PREDICTED: epidermal g ( 865) 344 77.3 2.1e-13
NP_001972 (OMIM: 600051) epidermal growth factor r ( 896) 344 77.3 2.2e-13
XP_016856104 (OMIM: 600051) PREDICTED: epidermal g ( 933) 344 77.3 2.2e-13
NP_001245305 (OMIM: 616826) epidermal growth facto ( 601) 326 73.6 1.9e-12
XP_016882581 (OMIM: 616826) PREDICTED: epidermal g ( 750) 326 73.7 2.2e-12
NP_001245304 (OMIM: 616826) epidermal growth facto ( 754) 326 73.8 2.2e-12
XP_016882580 (OMIM: 616826) PREDICTED: epidermal g ( 796) 326 73.8 2.2e-12
XP_016882579 (OMIM: 616826) PREDICTED: epidermal g ( 797) 326 73.8 2.2e-12
XP_016882578 (OMIM: 616826) PREDICTED: epidermal g ( 845) 326 73.8 2.3e-12
NP_067058 (OMIM: 616826) epidermal growth factor r ( 864) 326 73.8 2.4e-12
XP_016882577 (OMIM: 616826) PREDICTED: epidermal g ( 874) 326 73.8 2.4e-12
NP_001245303 (OMIM: 616826) epidermal growth facto ( 910) 326 73.8 2.4e-12
XP_016882576 (OMIM: 616826) PREDICTED: epidermal g ( 915) 326 73.8 2.5e-12
XP_016882575 (OMIM: 616826) PREDICTED: epidermal g ( 926) 326 73.9 2.5e-12
XP_011527995 (OMIM: 602442) PREDICTED: intersectin (1020) 269 62.9 5.4e-09
XP_016883930 (OMIM: 602442) PREDICTED: intersectin (1025) 269 62.9 5.5e-09
XP_011527994 (OMIM: 602442) PREDICTED: intersectin (1107) 269 62.9 5.7e-09
XP_016883929 (OMIM: 602442) PREDICTED: intersectin (1112) 269 62.9 5.8e-09
NP_001317940 (OMIM: 602442) intersectin-1 isoform (1144) 269 62.9 5.9e-09
NP_001317937 (OMIM: 602442) intersectin-1 isoform (1149) 269 62.9 5.9e-09
NP_001317941 (OMIM: 602442) intersectin-1 isoform (1178) 269 63.0 6e-09
XP_016883927 (OMIM: 602442) PREDICTED: intersectin (1183) 269 63.0 6e-09
NP_001317938 (OMIM: 602442) intersectin-1 isoform (1215) 269 63.0 6.1e-09
NP_001001132 (OMIM: 602442) intersectin-1 isoform (1220) 269 63.0 6.1e-09
XP_016883925 (OMIM: 602442) PREDICTED: intersectin (1608) 269 63.1 7.3e-09
XP_016883924 (OMIM: 602442) PREDICTED: intersectin (1613) 269 63.1 7.3e-09
XP_016883923 (OMIM: 602442) PREDICTED: intersectin (1645) 269 63.1 7.4e-09
XP_016883922 (OMIM: 602442) PREDICTED: intersectin (1650) 269 63.1 7.5e-09
XP_016883921 (OMIM: 602442) PREDICTED: intersectin (1660) 269 63.1 7.5e-09
XP_016883920 (OMIM: 602442) PREDICTED: intersectin (1665) 269 63.1 7.5e-09
XP_016883919 (OMIM: 602442) PREDICTED: intersectin (1679) 269 63.1 7.5e-09
XP_016883918 (OMIM: 602442) PREDICTED: intersectin (1684) 269 63.1 7.6e-09
NP_001317939 (OMIM: 602442) intersectin-1 isoform (1716) 269 63.1 7.7e-09
NP_003015 (OMIM: 602442) intersectin-1 isoform ITS (1721) 269 63.1 7.7e-09
>>NP_001269373 (OMIM: 605888) EH domain-containing prote (534 aa)
initn: 3552 init1: 3552 opt: 3552 Z-score: 3712.7 bits: 696.7 E(85289): 4.6e-200
Smith-Waterman score: 3552; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
430 440 450 460 470 480
490 500 510 520 530
pF1KB3 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
490 500 510 520 530
>>XP_011543041 (OMIM: 605888) PREDICTED: EH domain-conta (534 aa)
initn: 3552 init1: 3552 opt: 3552 Z-score: 3712.7 bits: 696.7 E(85289): 4.6e-200
Smith-Waterman score: 3552; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
430 440 450 460 470 480
490 500 510 520 530
pF1KB3 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
490 500 510 520 530
>>NP_006786 (OMIM: 605888) EH domain-containing protein (534 aa)
initn: 3552 init1: 3552 opt: 3552 Z-score: 3712.7 bits: 696.7 E(85289): 4.6e-200
Smith-Waterman score: 3552; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
430 440 450 460 470 480
490 500 510 520 530
pF1KB3 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
490 500 510 520 530
>>NP_001269374 (OMIM: 605888) EH domain-containing prote (548 aa)
initn: 3552 init1: 3552 opt: 3552 Z-score: 3712.6 bits: 696.7 E(85289): 4.7e-200
Smith-Waterman score: 3552; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:15-548)
10 20 30 40
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFH
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQPGTAASPVSGSMFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 SPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB3 GVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRIS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 RGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIET
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB3 QQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB3 RNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREH
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB3 QISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB3 QVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGAN
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB3 AKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLV
490 500 510 520 530 540
530
pF1KB3 PPSKRRHE
::::::::
NP_001 PPSKRRHE
>>NP_055415 (OMIM: 605891) EH domain-containing protein (535 aa)
initn: 3220 init1: 3188 opt: 3188 Z-score: 3332.7 bits: 626.4 E(85289): 6.8e-179
Smith-Waterman score: 3188; 87.0% identity (97.2% similar) in 532 aa overlap (1-532:1-532)
10 20 30 40 50 60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::.. : ::.:.::.::::.:::..:: .:::::::::::::::::::::::::::::
NP_055 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
::::::::::::::::.:.::::::::::::::::::::::.: ::..:::::::::..
NP_055 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
::::::::::::::::.:::::::::.:::.:::::::::::::::::::::::::::::
NP_055 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_055 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
:::.:::::.:::::::::::::::::::::::::::::.::::::::::::::::::::
NP_055 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
:::::::::::::::::::.::::..:::::::::.::: .:::::::::::::.:..::
NP_055 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
. ::.::::::: :: :::..::::::.:::.:::.:::::: : :.::::::.::..:
NP_055 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
::::::::::::::::.::::..::: :::::::::::.:::::::::::::.:::::.:
NP_055 PFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSV
430 440 450 460 470 480
490 500 510 520 530
pF1KB3 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
:::::::::.::::.:::.::::::::::::::::::: .:: ::.:::::.
NP_055 LGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
490 500 510 520 530
>>NP_644670 (OMIM: 605892) EH domain-containing protein (541 aa)
initn: 2795 init1: 2732 opt: 2759 Z-score: 2884.8 bits: 543.5 E(85289): 6e-154
Smith-Waterman score: 2759; 75.0% identity (91.6% similar) in 535 aa overlap (1-532:1-535)
10 20 30 40 50
pF1KB3 MFSWVSKDA---RRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDN
::::....: .: . :::. :::.:: .:.::::: ::::::::::::::::.:
NP_644 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 KPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVD
:::.:::::::::::::::.:.::::::::::::::::::::::.: ::: .::::::::
NP_644 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 PRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEW
:..:::::. :::::::::::.:::: :: :::.::.::::::::::::::::: ::.:
NP_644 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 FAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALM
:::::::::::::::::::::::::.:::.....::::::::::::..::::::::::::
NP_644 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 WSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDL
:::::.::::::.::::::::..:: :::.::::: ::::.::::::..::.::::::
NP_644 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 IKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLR
::::::::::::::: ::::::.:::::.::.::.. : ::: ...::.::: :::: ..
NP_644 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB3 KMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGT
::: :.. ::.::..:::::...::.::.: :. :: .. :::. :.:.:.:::::::
NP_644 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB3 MNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLP
.:::..:::::: :: :. ::::.::::.:::.::::::.::::.:.::::::: ::::
NP_644 TEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB3 NTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
:.:::::::::: : ::.::.::::::.::::.::.:.:::..:::::::::.:.
NP_644 NSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKA
490 500 510 520 530 540
NP_644 D
>>NP_055416 (OMIM: 605890) EH domain-containing protein (543 aa)
initn: 2598 init1: 2122 opt: 2608 Z-score: 2727.2 bits: 514.3 E(85289): 3.6e-145
Smith-Waterman score: 2608; 71.5% identity (90.0% similar) in 540 aa overlap (1-534:1-539)
10 20 30 40 50 60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::... . : ..:: ..::. .:..:: ::::::::::: ::::::::::::.:::
NP_055 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
::..::::::::.::..:.::. :: :.::::::: :.::::: :::.:::::::::: .
NP_055 VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
:::::: :::.:::::::::::: ::.::::::::::::: :::.:::::: :::.::::
NP_055 PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
::: ::::::::::.:::::::.: ::..:::::::::::::..::::::::::::::.:
NP_055 RVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
::...::::.:::::::::.:::.::::.::: ::::::.:::.:::.:::::::::.::
NP_055 GKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
:::..::::::: ::::::.:::::.:::.:. .: :. ::. ::.:::::::. .:::
NP_055 ARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQ
310 320 330 340 350 360
370 380 390 400 410
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQV-VKGGAFDGTMN
:::...::.::..::::::...:.::..:::.:: ..:::: : ..: :.::::.::
NP_055 ELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEE-LESTEVGVQGGAFEGTHM
370 380 390 400 410
420 430 440 450 460 470
pF1KB3 GPF---GHGYG-EGAGEGIDD-VEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKS
::: : . : . :: :: .:::: ::: ::::::.:.:..::..:..:: :: .
NP_055 GPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGT
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 KLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
::::.:::.::::.:::.::.:::::::::.:::..::::: :::.:: .:::::::::.
NP_055 KLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHK
480 490 500 510 520 530
NP_055 GSAE
540
>>XP_016877589 (OMIM: 605892) PREDICTED: EH domain-conta (453 aa)
initn: 2381 init1: 2348 opt: 2348 Z-score: 2456.7 bits: 464.0 E(85289): 4.2e-130
Smith-Waterman score: 2348; 75.8% identity (92.6% similar) in 447 aa overlap (86-532:1-447)
60 70 80 90 100 110
pF1KB3 DNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALV
::::::::::::::::.: ::: .::::::
XP_016 MRIGPEPTTDSFIAVMYGETEGSTPGNALV
10 20 30
120 130 140 150 160 170
pF1KB3 VDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVL
:::..:::::. :::::::::::.:::: :: :::.::.::::::::::::::::: ::
XP_016 VDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB3 EWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGA
.::::::::::::::::::::::::::.:::.....::::::::::::..::::::::::
XP_016 QWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB3 LMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLN
:::::::.::::::.::::::::..:: :::.::::: ::::.::::::..::.::::
XP_016 LMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLN
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB3 DLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPS
::::::::::::::::: ::::::.:::::.::.::.. : ::: ...::.::: ::::
XP_016 DLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPE
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB3 LRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFD
.. ::: :.. ::.::..:::::...::.::.: :. :: .. :::. :.:.:.:::::
XP_016 VKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFD
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB3 GTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSK
:: .:::..:::::: :: :. ::::.::::.:::.::::::.::::.:.::::::: ::
XP_016 GTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSK
340 350 360 370 380 390
480 490 500 510 520 530
pF1KB3 LPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
:::.:::::::::: : ::.::.::::::.::::.::.:.:::..:::::::::.:.
XP_016 LPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLP
400 410 420 430 440 450
XP_016 KAD
>>XP_011531108 (OMIM: 605891) PREDICTED: EH domain-conta (322 aa)
initn: 1905 init1: 1873 opt: 1875 Z-score: 1964.7 bits: 372.5 E(85289): 1.1e-102
Smith-Waterman score: 1875; 85.9% identity (96.9% similar) in 319 aa overlap (214-532:1-319)
190 200 210 220 230 240
pF1KB3 RIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKI
.:::::::::::::::::::::::::::::
XP_011 MRVVLNKADQIETQQLMRVYGALMWSLGKI
10 20 30
250 260 270 280 290 300
pF1KB3 INTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARL
.:::::.:::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 VNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARL
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB3 AKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELL
::::::::::::::::.::::..:::::::::.::: .:::::::::::::.:..::. :
XP_011 AKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQL
100 110 120 130 140 150
370 380 390 400 410 420
pF1KB3 QTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNGPFG
:.::::::: :: :::..::::::.:::.:::.:::::: : :.::::::.::..::::
XP_011 QAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHGPFG
160 170 180 190 200 210
430 440 450 460 470 480
pF1KB3 HGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGK
:::::::::::::.::::..::: :::::::::::.:::::::::::::.:::::.::::
XP_011 HGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGK
220 230 240 250 260 270
490 500 510 520 530
pF1KB3 IWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
::::::.::::.:::.::::::::::::::::::: .:: ::.:::::.
XP_011 IWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
280 290 300 310 320
>>NP_001310597 (OMIM: 604992) sarcalumenin isoform 2 [Ho (431 aa)
initn: 533 init1: 390 opt: 765 Z-score: 804.6 bits: 158.3 E(85289): 4.5e-38
Smith-Waterman score: 765; 33.2% identity (69.4% similar) in 373 aa overlap (13-377:6-377)
10 20 30 40 50 60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
: . ...: . ::..: ... :::. :...:... . :... .:::
NP_001 MLNEDKPSDDYSAVLQRLRKIYHSSIKPLEQSYKYNELRQHEITDGEITSKPM
10 20 30 40 50
70 80 90 100 110
pF1KB3 VLLVGQYSTGKTTFIRHLI--EQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDP
::..: .:.::.:.: .:. :. . : ::::. : ..:::: .. : ....:
NP_001 VLFLGPWSVGKSTMINYLLGLENTRYQLYTGAEPTTSEFTVLMHGPKLKTIEGIVMAADS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 RRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWF
: : :. ::. ::.... ..:. .:. ....:::::. ..::. ::: : : .::
NP_001 ARSFSPLEKFGQNFLEKLIGIEVPHKLLERVTFVDTPGIIENRKQQ-ERGYPFNDVCQWF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 AERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMW
.:.: :...:: :::.. :. ... ::..:..::..:::::.. ::.::::::::.:
NP_001 IDRADLIFVVFDPTKLDVGLELEMLFRQLKGRESQIRIILNKADNLATQMLMRVYGALFW
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 SLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLI
::. .::. : :::..::: . ...:: :: .:..:.... .: :. .
NP_001 SLAPLINVTEPPRVYVSSFWPQEYKPDTHQELFLQEEISLLEDLNQVIENRLENKIAFIR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 KRARLAKVHAYIIS----SLKKEMPNVFGKESKKKELVNNLGE--IYQKIEREHQISPGD
..: ...:: ... . : .: : :..:.. . :.. : . ..: :
NP_001 QHAIRVRIHALLVDRYLQTYKDKMTFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFD
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 FPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGG
.:. . ..... . .:.:. :. .
NP_001 LPNREAYKDFFGINPISSFKLLSQQCSYMGGCFLEKIERAITQELPGLLGSLGLGKNPGA
360 370 380 390 400 410
534 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:20:42 2016 done: Thu Nov 3 13:20:43 2016
Total Scan time: 8.940 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]