Result of FASTA (omim) for
pFN21AB3411
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3411, 899 aa
1>>>pF1KB3411 899 - 899 aa - 899 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7955+/-0.00043; mu= 6.4460+/- 0.027
mean_var=305.2219+/-61.270, 0's: 0 Z-trim(121.5): 288 B-trim: 901 in 1/51
Lambda= 0.073412
statistics sampled from 37801 (38180) to 37801 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.448), width: 16
Scan time: 14.540
The best scores are: opt bits E(85289)
NP_002493 (OMIM: 164012,615577) nuclear factor NF- ( 899) 6027 652.9 1.9e-186
NP_001275653 (OMIM: 164012,615577) nuclear factor ( 899) 6027 652.9 1.9e-186
NP_001248332 (OMIM: 164012,615577) nuclear factor ( 899) 6027 652.9 1.9e-186
NP_001309863 (OMIM: 164012,615577) nuclear factor ( 900) 6015 651.7 4.7e-186
NP_001070962 (OMIM: 164012,615577) nuclear factor ( 900) 6015 651.7 4.7e-186
XP_016871767 (OMIM: 164012,615577) PREDICTED: nucl (1081) 5965 646.5 2.1e-184
XP_011538132 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 5008 544.9 5.3e-154
XP_011538133 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 5008 544.9 5.3e-154
NP_001309864 (OMIM: 164012,615577) nuclear factor ( 858) 3486 383.8 1.9e-105
NP_001306155 (OMIM: 164011,616576) nuclear factor ( 968) 923 112.4 1.1e-23
NP_001158884 (OMIM: 164011,616576) nuclear factor ( 968) 923 112.4 1.1e-23
NP_003989 (OMIM: 164011,616576) nuclear factor NF- ( 969) 923 112.4 1.1e-23
XP_011530308 (OMIM: 164011,616576) PREDICTED: nucl ( 976) 923 112.4 1.1e-23
XP_011530310 (OMIM: 164011,616576) PREDICTED: nucl ( 916) 761 95.2 1.5e-18
XP_011531312 (OMIM: 164910) PREDICTED: proto-oncog ( 489) 523 69.7 4e-11
NP_001278675 (OMIM: 164910) proto-oncogene c-Rel i ( 587) 523 69.8 4.5e-11
XP_016860116 (OMIM: 164910) PREDICTED: proto-oncog ( 564) 522 69.6 4.7e-11
NP_002899 (OMIM: 164910) proto-oncogene c-Rel isof ( 619) 520 69.5 5.8e-11
NP_005169 (OMIM: 109560) B-cell lymphoma 3 protein ( 454) 508 68.1 1.1e-10
XP_011525499 (OMIM: 109560) PREDICTED: B-cell lymp ( 539) 508 68.1 1.3e-10
XP_016882599 (OMIM: 109560) PREDICTED: B-cell lymp ( 356) 504 67.5 1.3e-10
XP_011525502 (OMIM: 109560) PREDICTED: B-cell lymp ( 378) 504 67.5 1.4e-10
XP_016882598 (OMIM: 109560) PREDICTED: B-cell lymp ( 434) 504 67.6 1.5e-10
XP_011525500 (OMIM: 109560) PREDICTED: B-cell lymp ( 696) 504 67.8 2e-10
XP_005259184 (OMIM: 604758) PREDICTED: transcripti ( 576) 477 64.9 1.3e-09
NP_006500 (OMIM: 604758) transcription factor RelB ( 579) 477 64.9 1.3e-09
NP_004547 (OMIM: 604548) NF-kappa-B inhibitor epsi ( 500) 460 63.0 4.1e-09
NP_065390 (OMIM: 164008,612132) NF-kappa-B inhibit ( 317) 396 56.0 3.4e-07
XP_011543509 (OMIM: 164014) PREDICTED: transcripti ( 445) 397 56.3 3.9e-07
NP_001230914 (OMIM: 164014) transcription factor p ( 448) 397 56.3 3.9e-07
XP_011543508 (OMIM: 164014) PREDICTED: transcripti ( 480) 397 56.3 4.1e-07
NP_001230913 (OMIM: 164014) transcription factor p ( 482) 397 56.3 4.1e-07
NP_068810 (OMIM: 164014) transcription factor p65 ( 551) 397 56.4 4.5e-07
NP_001138610 (OMIM: 164014) transcription factor p ( 548) 395 56.2 5.1e-07
XP_005259185 (OMIM: 604758) PREDICTED: transcripti ( 507) 346 51.0 1.8e-05
XP_016881362 (OMIM: 608677,615092) PREDICTED: E3 u ( 834) 313 47.7 0.00028
NP_065825 (OMIM: 608677,615092) E3 ubiquitin-prote (1006) 313 47.8 0.00031
XP_011524400 (OMIM: 608677,615092) PREDICTED: E3 u ( 516) 299 46.0 0.00057
NP_002494 (OMIM: 604495) NF-kappa-B inhibitor beta ( 356) 280 43.8 0.0018
>>NP_002493 (OMIM: 164012,615577) nuclear factor NF-kapp (899 aa)
initn: 6027 init1: 6027 opt: 6027 Z-score: 3468.1 bits: 652.9 E(85289): 1.9e-186
Smith-Waterman score: 6027; 100.0% identity (100.0% similar) in 899 aa overlap (1-899:1-899)
10 20 30 40 50 60
pF1KB3 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
790 800 810 820 830 840
850 860 870 880 890
pF1KB3 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
850 860 870 880 890
>>NP_001275653 (OMIM: 164012,615577) nuclear factor NF-k (899 aa)
initn: 6027 init1: 6027 opt: 6027 Z-score: 3468.1 bits: 652.9 E(85289): 1.9e-186
Smith-Waterman score: 6027; 100.0% identity (100.0% similar) in 899 aa overlap (1-899:1-899)
10 20 30 40 50 60
pF1KB3 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
790 800 810 820 830 840
850 860 870 880 890
pF1KB3 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
850 860 870 880 890
>>NP_001248332 (OMIM: 164012,615577) nuclear factor NF-k (899 aa)
initn: 6027 init1: 6027 opt: 6027 Z-score: 3468.1 bits: 652.9 E(85289): 1.9e-186
Smith-Waterman score: 6027; 100.0% identity (100.0% similar) in 899 aa overlap (1-899:1-899)
10 20 30 40 50 60
pF1KB3 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
790 800 810 820 830 840
850 860 870 880 890
pF1KB3 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
850 860 870 880 890
>>NP_001309863 (OMIM: 164012,615577) nuclear factor NF-k (900 aa)
initn: 5942 init1: 5747 opt: 6015 Z-score: 3461.3 bits: 651.7 E(85289): 4.7e-186
Smith-Waterman score: 6015; 99.9% identity (99.9% similar) in 900 aa overlap (1-899:1-900)
10 20 30 40 50 60
pF1KB3 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
790 800 810 820 830 840
850 860 870 880 890
pF1KB3 EEGVRLLRGPETRDKLPST-EVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 EEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
850 860 870 880 890 900
>>NP_001070962 (OMIM: 164012,615577) nuclear factor NF-k (900 aa)
initn: 5942 init1: 5747 opt: 6015 Z-score: 3461.3 bits: 651.7 E(85289): 4.7e-186
Smith-Waterman score: 6015; 99.9% identity (99.9% similar) in 900 aa overlap (1-899:1-900)
10 20 30 40 50 60
pF1KB3 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
790 800 810 820 830 840
850 860 870 880 890
pF1KB3 EEGVRLLRGPETRDKLPST-EVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 EEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
850 860 870 880 890 900
>>XP_016871767 (OMIM: 164012,615577) PREDICTED: nuclear (1081 aa)
initn: 5886 init1: 5691 opt: 5965 Z-score: 3431.7 bits: 646.5 E(85289): 2.1e-184
Smith-Waterman score: 5965; 99.8% identity (99.8% similar) in 895 aa overlap (6-899:187-1081)
10 20 30
pF1KB3 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETA
: ::::::::::::::::::::::::::::
XP_016 ILGSRTWPEPLDRAGPSPETWRVATTHLSPNQGLDGIIEYDDFKLNSSIVEPKEPAPETA
160 170 180 190 200 210
40 50 60 70 80 90
pF1KB3 DGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDL
220 230 240 250 260 270
100 110 120 130 140 150
pF1KB3 VTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQ
280 290 300 310 320 330
160 170 180 190 200 210
pF1KB3 RQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQ
340 350 360 370 380 390
220 230 240 250 260 270
pF1KB3 PIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGD
400 410 420 430 440 450
280 290 300 310 320 330
pF1KB3 FSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEV
460 470 480 490 500 510
340 350 360 370 380 390
pF1KB3 QRKRRKALPTFSQPFGGGSHMGGGSGGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRKRRKALPTFSQPFGGGSHMGGGSGGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPM
520 530 540 550 560 570
400 410 420 430 440 450
pF1KB3 GCYPGGGGGAQMAATVPSRDSGEEAAEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCYPGGGGGAQMAATVPSRDSGEEAAEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQ
580 590 600 610 620 630
460 470 480 490 500 510
pF1KB3 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ
640 650 660 670 680 690
520 530 540 550 560 570
pF1KB3 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP
700 710 720 730 740 750
580 590 600 610 620 630
pF1KB3 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR
760 770 780 790 800 810
640 650 660 670 680 690
pF1KB3 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH
820 830 840 850 860 870
700 710 720 730 740 750
pF1KB3 AENEEPLCPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AENEEPLCPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTME
880 890 900 910 920 930
760 770 780 790 800 810
pF1KB3 PPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSG
940 950 960 970 980 990
820 830 840 850 860 870
pF1KB3 SLLRSYELAGGDLAGLLEALSDMGLEEGVRLLRGPETRDKLPST-EVKEDSAYGSQSVEQ
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 SLLRSYELAGGDLAGLLEALSDMGLEEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQ
1000 1010 1020 1030 1040 1050
880 890
pF1KB3 EAEKLGPPPEPPGGLCHGHPQPQVH
:::::::::::::::::::::::::
XP_016 EAEKLGPPPEPPGGLCHGHPQPQVH
1060 1070 1080
>>XP_011538132 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa)
initn: 4935 init1: 4740 opt: 5008 Z-score: 2885.7 bits: 544.9 E(85289): 5.3e-154
Smith-Waterman score: 5008; 99.9% identity (99.9% similar) in 755 aa overlap (146-899:1-755)
120 130 140 150 160 170
pF1KB3 ELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELE
::::::::::::::::::::::::::::::
XP_011 MMGTMIQKLQRQRLRSRPQGLTEAEQRELE
10 20 30
180 190 200 210 220 230
pF1KB3 QEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDK
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB3 TAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYH
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB3 KMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSH
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB3 MGGGSGGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGGSGGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRD
220 230 240 250 260 270
420 430 440 450 460 470
pF1KB3 SGEEAAEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGEEAAEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLA
280 290 300 310 320 330
480 490 500 510 520 530
pF1KB3 GQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAV
340 350 360 370 380 390
540 550 560 570 580 590
pF1KB3 ITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHM
400 410 420 430 440 450
600 610 620 630 640 650
pF1KB3 PDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVT
460 470 480 490 500 510
660 670 680 690 700 710
pF1KB3 KLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDS
520 530 540 550 560 570
720 730 740 750 760 770
pF1KB3 DSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTAL
580 590 600 610 620 630
780 790 800 810 820 830
pF1KB3 QNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEAL
640 650 660 670 680 690
840 850 860 870 880 890
pF1KB3 SDMGLEEGVRLLRGPETRDKLPST-EVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHP
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 SDMGLEEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHP
700 710 720 730 740 750
pF1KB3 QPQVH
:::::
XP_011 QPQVH
>>XP_011538133 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa)
initn: 4935 init1: 4740 opt: 5008 Z-score: 2885.7 bits: 544.9 E(85289): 5.3e-154
Smith-Waterman score: 5008; 99.9% identity (99.9% similar) in 755 aa overlap (146-899:1-755)
120 130 140 150 160 170
pF1KB3 ELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELE
::::::::::::::::::::::::::::::
XP_011 MMGTMIQKLQRQRLRSRPQGLTEAEQRELE
10 20 30
180 190 200 210 220 230
pF1KB3 QEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDK
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB3 TAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYH
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB3 KMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSH
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB3 MGGGSGGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGGSGGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRD
220 230 240 250 260 270
420 430 440 450 460 470
pF1KB3 SGEEAAEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGEEAAEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLA
280 290 300 310 320 330
480 490 500 510 520 530
pF1KB3 GQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAV
340 350 360 370 380 390
540 550 560 570 580 590
pF1KB3 ITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHM
400 410 420 430 440 450
600 610 620 630 640 650
pF1KB3 PDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVT
460 470 480 490 500 510
660 670 680 690 700 710
pF1KB3 KLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDS
520 530 540 550 560 570
720 730 740 750 760 770
pF1KB3 DSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTAL
580 590 600 610 620 630
780 790 800 810 820 830
pF1KB3 QNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEAL
640 650 660 670 680 690
840 850 860 870 880 890
pF1KB3 SDMGLEEGVRLLRGPETRDKLPST-EVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHP
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 SDMGLEEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHP
700 710 720 730 740 750
pF1KB3 QPQVH
:::::
XP_011 QPQVH
>>NP_001309864 (OMIM: 164012,615577) nuclear factor NF-k (858 aa)
initn: 5624 init1: 3218 opt: 3486 Z-score: 2013.9 bits: 383.8 E(85289): 1.9e-105
Smith-Waterman score: 5625; 95.2% identity (95.2% similar) in 900 aa overlap (1-899:1-858)
10 20 30 40 50 60
pF1KB3 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
::::::::::::::::::::::::::::::
NP_001 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVE------------------------------
310 320 330
370 380 390 400 410 420
pF1KB3 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------GGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
340 350 360 370
430 440 450 460 470 480
pF1KB3 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB3 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB3 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB3 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
560 570 580 590 600 610
670 680 690 700 710 720
pF1KB3 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
620 630 640 650 660 670
730 740 750 760 770 780
pF1KB3 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
680 690 700 710 720 730
790 800 810 820 830 840
pF1KB3 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
740 750 760 770 780 790
850 860 870 880 890
pF1KB3 EEGVRLLRGPETRDKLPST-EVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 EEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
800 810 820 830 840 850
>>NP_001306155 (OMIM: 164011,616576) nuclear factor NF-k (968 aa)
initn: 1759 init1: 463 opt: 923 Z-score: 546.3 bits: 112.4 E(85289): 1.1e-23
Smith-Waterman score: 2240; 44.8% identity (68.5% similar) in 899 aa overlap (17-858:18-899)
10 20 30 40 50
pF1KB3 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETA---DGPYLVIVEQPKQRGFRFRYG
: .:. .: .:. :. : ::::: :.::::::::::::
NP_001 MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 CEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSE
::::::::::::::::..:.:: :::::: ::::. :.:::.. . ::::::::.: :
NP_001 CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHC-E
70 80 90 100 110
120 130 140 150 160
pF1KB3 LGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLT--------E
:::.:..:::::.. : :::.::::::... :. .. . .:. :: .
NP_001 DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ
120 130 140 150 160 170
170 180 190 200 210
pF1KB3 AE---QRELEQEAKEL--------KKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPI
:: .:.: .. ::: : ::::.::: :.::: : :::. :.::.:. :
NP_001 AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB3 HDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENG--WQAFGD
.:::.:.:::::: :::.::: : ::.:.::::::::::::..::::..::: :..:::
NP_001 YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB3 FSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEV
:::::::.:.::::.:: :. ..: .:..::.::.:: ..:. : : ::: ..:::::
NP_001 FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV
300 310 320 330 340 350
340 350 360 370 380
pF1KB3 QRKRRKALPTFSQPFGGGSHMGGGSGGAAGGYGGAGGGGSLG----F----FPS--SLAY
::::.: .:.::. ::::: :.:.:: :. ::.:: :: : : ::. ....
NP_001 QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF
360 370 380 390 400 410
390 400 410 420
pF1KB3 SP--YQSGAG-------------PMGCYPGGGGGA--QMAATVPSRDSGEEAAEPSAP--
: .:.:: : :: . .. .. .. . .. .: .: ..
NP_001 HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG
420 430 440 450 460 470
430 440 450 460 470 480
pF1KB3 --SRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHLLTAQ
. : . . . . . ::.: : ::.::.::.:.. ::: :::: ..:
NP_001 EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ
480 490 500 510 520 530
490 500 510 520 530 540
pF1KB3 DENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVS
:::::. ::::::: ......... : . ..:. : :.:::::::::: : .::
NP_001 DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE
540 550 560 570 580 590
550 560 570 580 590 600
pF1KB3 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV
:::.::: .:::: :.:..::: : : ..: ::. :. :: :. .:: .
NP_001 DLLRAGADLSLLDRLGNSVLHLA--AKEGHDKVLSILLKHKKAAL--LLDHPNGDGLNAI
600 610 620 630 640 650
610 620 630 640 650 660
pF1KB3 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR
:::. . : :: ::: .::.:.: :...::::::::.: ....:. :. . :.:..
NP_001 HLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDST
660 670 680 690 700 710
670 680 690 700 710 720
pF1KB3 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT
:. :.::::.::: : :. :: :::: .:: ::: : :.. :. .:
NP_001 TYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPL--------YDLDDSWENAGED-
720 730 740 750 760
730 740 750 760 770 780
pF1KB3 RSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPS--PAGPGLSLGDTALQNLEQLL
.. : ::::.. : .: .: :. . .:: .: . : .:.. . .: .::
NP_001 EGVVPGTTPLDMATSWQVFDIL-NG--KPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLL
770 780 790 800 810 820
790 800 810 820 830 840
pF1KB3 DGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEE
. :. . .:: ::..::: : ...: . .:: .:. .::..:: . :.::: .:: :
NP_001 EIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTE
830 840 850 860 870 880
850 860 870 880 890
pF1KB3 GVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
....... . : :
NP_001 AIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLT
890 900 910 920 930 940
899 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:13:42 2016 done: Thu Nov 3 13:13:44 2016
Total Scan time: 14.540 Total Display time: 0.400
Function used was FASTA [36.3.4 Apr, 2011]