Result of FASTA (ccds) for
pFN21AA0987
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0987, 1087 aa
1>>>pF1KA0987 1087 - 1087 aa - 1087 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6472+/-0.000932; mu= 11.9901+/- 0.056
mean_var=128.1364+/-24.997, 0's: 0 Z-trim(110.0): 76 B-trim: 0 in 0/51
Lambda= 0.113302
statistics sampled from 11193 (11269) to 11193 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.346), width: 16
Scan time: 5.240
The best scores are: opt bits E(32554)
CCDS11838.1 EPB41L3 gene_id:23136|Hs108|chr18 (1087) 7097 1171.9 0
CCDS62381.1 EPB41L3 gene_id:23136|Hs108|chr18 ( 865) 2989 500.4 7.2e-141
CCDS62382.1 EPB41L3 gene_id:23136|Hs108|chr18 ( 883) 2989 500.4 7.3e-141
CCDS82237.1 EPB41L3 gene_id:23136|Hs108|chr18 ( 918) 2989 500.4 7.6e-141
CCDS82236.1 EPB41L3 gene_id:23136|Hs108|chr18 ( 756) 2297 387.2 7.2e-107
CCDS58771.1 EPB41L1 gene_id:2036|Hs108|chr20 ( 880) 2116 357.7 6.6e-98
CCDS13271.1 EPB41L1 gene_id:2036|Hs108|chr20 ( 881) 2116 357.7 6.6e-98
CCDS58770.1 EPB41L1 gene_id:2036|Hs108|chr20 ( 701) 2057 348.0 4.4e-95
CCDS13272.1 EPB41L1 gene_id:2036|Hs108|chr20 ( 779) 2051 347.0 9.4e-95
CCDS59037.1 EPB41L2 gene_id:2037|Hs108|chr6 ( 747) 1943 329.4 1.9e-89
CCDS47474.1 EPB41L2 gene_id:2037|Hs108|chr6 ( 673) 1937 328.4 3.4e-89
CCDS56450.1 EPB41L2 gene_id:2037|Hs108|chr6 ( 852) 1937 328.4 4.1e-89
CCDS5141.1 EPB41L2 gene_id:2037|Hs108|chr6 (1005) 1937 328.4 4.8e-89
CCDS53288.1 EPB41 gene_id:2035|Hs108|chr1 ( 864) 1827 310.4 1.1e-83
CCDS53289.1 EPB41 gene_id:2035|Hs108|chr1 ( 720) 1821 309.4 1.8e-83
CCDS331.1 EPB41 gene_id:2035|Hs108|chr1 ( 588) 1747 297.3 6.7e-80
CCDS332.1 EPB41 gene_id:2035|Hs108|chr1 ( 641) 1747 297.3 7.2e-80
CCDS330.1 EPB41 gene_id:2035|Hs108|chr1 ( 775) 1539 263.3 1.5e-69
CCDS2129.1 PTPN4 gene_id:5775|Hs108|chr2 ( 926) 1055 184.3 1.1e-45
CCDS9487.1 FARP1 gene_id:10160|Hs108|chr13 (1045) 949 167.0 2e-40
CCDS66572.1 FARP1 gene_id:10160|Hs108|chr13 (1076) 949 167.0 2.1e-40
CCDS54392.1 EPB41L5 gene_id:57669|Hs108|chr2 ( 505) 934 164.4 6e-40
CCDS54393.1 EPB41L5 gene_id:57669|Hs108|chr2 ( 687) 934 164.4 7.8e-40
CCDS82506.1 EPB41L5 gene_id:57669|Hs108|chr2 ( 732) 934 164.4 8.2e-40
CCDS2130.1 EPB41L5 gene_id:57669|Hs108|chr2 ( 733) 934 164.4 8.2e-40
CCDS43860.1 EPB41L4B gene_id:54566|Hs108|chr9 ( 518) 905 159.6 1.6e-38
CCDS43859.1 EPB41L4B gene_id:54566|Hs108|chr9 ( 900) 905 159.7 2.6e-38
CCDS59133.1 FRMD3 gene_id:257019|Hs108|chr9 ( 556) 888 156.9 1.2e-37
CCDS43840.1 FRMD3 gene_id:257019|Hs108|chr9 ( 597) 888 156.9 1.3e-37
CCDS63198.1 FARP2 gene_id:9855|Hs108|chr2 ( 638) 886 156.6 1.7e-37
CCDS63197.1 FARP2 gene_id:9855|Hs108|chr2 ( 647) 886 156.6 1.7e-37
CCDS33424.1 FARP2 gene_id:9855|Hs108|chr2 (1054) 886 156.7 2.6e-37
CCDS43350.1 EPB41L4A gene_id:64097|Hs108|chr5 ( 686) 876 154.9 5.5e-37
CCDS10107.2 FRMD5 gene_id:84978|Hs108|chr15 ( 570) 835 148.2 4.9e-35
CCDS35397.1 FRMD7 gene_id:90167|Hs108|chrX ( 714) 826 146.8 1.7e-34
CCDS75852.1 FRMD3 gene_id:257019|Hs108|chr9 ( 553) 821 145.9 2.3e-34
CCDS6776.1 PTPN3 gene_id:5774|Hs108|chr9 ( 913) 768 137.3 1.5e-31
CCDS78504.1 FRMD7 gene_id:90167|Hs108|chrX ( 699) 627 114.2 1e-24
CCDS73716.1 FRMD5 gene_id:84978|Hs108|chr15 ( 414) 565 104.0 7.2e-22
CCDS9884.1 PTPN21 gene_id:11099|Hs108|chr14 (1174) 561 103.6 2.8e-21
CCDS48001.1 PTPN3 gene_id:5774|Hs108|chr9 ( 782) 518 96.4 2.6e-19
CCDS48000.1 PTPN3 gene_id:5774|Hs108|chr9 ( 737) 507 94.6 8.5e-19
CCDS4536.1 MYLIP gene_id:29116|Hs108|chr6 ( 445) 428 81.6 4.2e-15
CCDS1514.1 PTPN14 gene_id:5784|Hs108|chr1 (1187) 435 83.0 4.5e-15
CCDS5258.1 EZR gene_id:7430|Hs108|chr6 ( 586) 355 69.7 2.1e-11
CCDS8343.1 RDX gene_id:5962|Hs108|chr11 ( 583) 344 67.9 7.3e-11
CCDS58174.1 RDX gene_id:5962|Hs108|chr11 ( 604) 344 68.0 7.5e-11
>>CCDS11838.1 EPB41L3 gene_id:23136|Hs108|chr18 (1087 aa)
initn: 7097 init1: 7097 opt: 7097 Z-score: 6270.0 bits: 1171.9 E(32554): 0
Smith-Waterman score: 7097; 100.0% identity (100.0% similar) in 1087 aa overlap (1-1087:1-1087)
10 20 30 40 50 60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEKKAEEERDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEKKAEEERDE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 VHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 AKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 VSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 HITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI
1030 1040 1050 1060 1070 1080
pF1KA0 TPEDGED
:::::::
CCDS11 TPEDGED
>>CCDS62381.1 EPB41L3 gene_id:23136|Hs108|chr18 (865 aa)
initn: 4943 init1: 2989 opt: 2989 Z-score: 2642.5 bits: 500.4 E(32554): 7.2e-141
Smith-Waterman score: 4916; 76.7% identity (76.7% similar) in 1105 aa overlap (1-1087:1-865)
10 20 30 40 50 60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
370 380 390 400 410 420
430 440 450 460
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDG------------------EVGTGQYATTKGISQT
:::::::::::::::::::::::::: ::::::::::::::::
CCDS62 ALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQT
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAP
::::::::::::::::::::::::::::::::::::::::
CCDS62 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGK--------------------
490 500 510 520
530 540 550 560 570 580
pF1KA0 TSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKG
CCDS62 ------------------------------------------------------------
590 600 610 620 630 640
pF1KA0 TTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFF
CCDS62 ------------------------------------------------------------
650 660 670 680 690 700
pF1KA0 LLSASFSVPYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGE
:::::::::::::
CCDS62 -----------------------------------------------TDSERTDTAADGE
530
710 720 730 740 750 760
pF1KA0 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
::::: :::::::::::::::::::::::::::::::::::::::::::
CCDS62 TTATE------------ELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
540 550 560 570 580
770 780 790 800 810 820
pF1KA0 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
:::::::::::::::::::::
CCDS62 PVRLAARQEDAPMIEPLVPEE---------------------------------------
590 600
830 840 850 860 870 880
pF1KA0 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 --KMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
610 620 630 640 650 660
890 900 910 920 930 940
pF1KA0 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
670 680 690 700 710 720
950 960 970 980 990 1000
pF1KA0 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
730 740 750 760 770 780
1010 1020 1030 1040 1050 1060
pF1KA0 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
790 800 810 820 830 840
1070 1080
pF1KA0 QHPDMSVTKVVVHKETEITPEDGED
:::::::::::::::::::::::::
CCDS62 QHPDMSVTKVVVHKETEITPEDGED
850 860
>>CCDS62382.1 EPB41L3 gene_id:23136|Hs108|chr18 (883 aa)
initn: 5216 init1: 2989 opt: 2989 Z-score: 2642.4 bits: 500.4 E(32554): 7.3e-141
Smith-Waterman score: 5146; 80.8% identity (80.8% similar) in 1069 aa overlap (1-1051:1-882)
10 20 30 40 50 60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
370 380 390 400 410 420
430 440 450 460
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDG------------------EVGTGQYATTKGISQT
:::::::::::::::::::::::::: ::::::::::::::::
CCDS62 ALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQT
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAP
::::::::::::::::::::::::::::::::::::::::
CCDS62 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGK--------------------
490 500 510 520
530 540 550 560 570 580
pF1KA0 TSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKG
CCDS62 ------------------------------------------------------------
590 600 610 620 630 640
pF1KA0 TTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFF
CCDS62 ------------------------------------------------------------
650 660 670 680 690 700
pF1KA0 LLSASFSVPYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGE
:::::::::::::
CCDS62 -----------------------------------------------TDSERTDTAADGE
530
710 720 730 740 750 760
pF1KA0 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
540 550 560 570 580 590
770 780 790 800 810 820
pF1KA0 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
600 610 620 630 640 650
830 840 850 860 870 880
pF1KA0 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
660 670 680 690 700 710
890 900 910 920 930 940
pF1KA0 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
720 730 740 750 760 770
950 960 970 980 990 1000
pF1KA0 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
780 790 800 810 820 830
1010 1020 1030 1040 1050 1060
pF1KA0 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQE
840 850 860 870 880
1070 1080
pF1KA0 QHPDMSVTKVVVHKETEITPEDGED
>>CCDS82237.1 EPB41L3 gene_id:23136|Hs108|chr18 (918 aa)
initn: 5444 init1: 2989 opt: 2989 Z-score: 2642.1 bits: 500.4 E(32554): 7.6e-141
Smith-Waterman score: 5374; 81.4% identity (81.4% similar) in 1105 aa overlap (1-1087:1-918)
10 20 30 40 50 60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
370 380 390 400 410 420
430 440 450 460
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDG------------------EVGTGQYATTKGISQT
:::::::::::::::::::::::::: ::::::::::::::::
CCDS82 ALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQT
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAP
::::::::::::::::::::::::::::::::::::::::
CCDS82 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGK--------------------
490 500 510 520
530 540 550 560 570 580
pF1KA0 TSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKG
CCDS82 ------------------------------------------------------------
590 600 610 620 630 640
pF1KA0 TTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFF
CCDS82 ------------------------------------------------------------
650 660 670 680 690 700
pF1KA0 LLSASFSVPYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGE
:::::::::::::
CCDS82 -----------------------------------------------TDSERTDTAADGE
530
710 720 730 740 750 760
pF1KA0 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
540 550 560 570 580 590
770 780 790 800 810 820
pF1KA0 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
600 610 620 630 640 650
830 840 850 860 870 880
pF1KA0 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
660 670 680 690 700 710
890 900 910 920 930 940
pF1KA0 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
720 730 740 750 760 770
950 960 970 980 990 1000
pF1KA0 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
780 790 800 810 820 830
1010 1020 1030 1040 1050 1060
pF1KA0 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
840 850 860 870 880 890
1070 1080
pF1KA0 QHPDMSVTKVVVHKETEITPEDGED
:::::::::::::::::::::::::
CCDS82 QHPDMSVTKVVVHKETEITPEDGED
900 910
>>CCDS82236.1 EPB41L3 gene_id:23136|Hs108|chr18 (756 aa)
initn: 4251 init1: 2297 opt: 2297 Z-score: 2032.1 bits: 387.2 E(32554): 7.2e-107
Smith-Waterman score: 4224; 74.1% identity (74.1% similar) in 996 aa overlap (110-1087:1-756)
80 90 100 110 120 130
pF1KA0 QQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKV
::::::::::::::::::::::::::::::
CCDS82 MQCKVILLDGSEYTCDVEKRSRGQVLFDKV
10 20 30
140 150 160 170 180 190
pF1KA0 CEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSED
40 50 60 70 80 90
200 210 220 230 240 250
pF1KA0 ITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNH
100 110 120 130 140 150
260 270 280 290 300 310
pF1KA0 TKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASG
160 170 180 190 200 210
320 330 340 350 360 370
pF1KA0 LLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKV
220 230 240 250 260 270
380 390 400 410 420 430
pF1KA0 CVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYT
280 290 300 310 320 330
440 450 460 470 480
pF1KA0 MSRSLDG------------------EVGTGQYATTKGISQTNLITTVTPEKKAEEERDEE
::::::: :::::::::::::::::::::::::::::::::::
CCDS82 MSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQTNLITTVTPEKKAEEERDEE
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 EDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLPG
:::::::::::::::::::::
CCDS82 EDKRRKGEEVTPISAIRHEGK---------------------------------------
400 410
550 560 570 580 590 600
pF1KA0 YEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLLD
CCDS82 ------------------------------------------------------------
610 620 630 640 650 660
pF1KA0 DDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPLA
CCDS82 ------------------------------------------------------------
670 680 690 700 710 720
pF1KA0 LCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQEL
:::::::::::::::::: ::
CCDS82 ----------------------------TDSERTDTAADGETTATE------------EL
420 430
730 740 750 760 770 780
pF1KA0 EKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVP
440 450 460 470 480 490
790 800 810 820 830 840
pF1KA0 EETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPTV
:: :::::::::::::::::
CCDS82 EE-----------------------------------------KMETKTESSGIETEPTV
500 510
850 860 870 880 890 900
pF1KA0 HHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 HHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGA
520 530 540 550 560 570
910 920 930 940 950 960
pF1KA0 KEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGSV
580 590 600 610 620 630
970 980 990 1000 1010 1020
pF1KA0 SPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTTH
640 650 660 670 680 690
1030 1040 1050 1060 1070 1080
pF1KA0 ITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEIT
700 710 720 730 740 750
pF1KA0 PEDGED
::::::
CCDS82 PEDGED
>>CCDS58771.1 EPB41L1 gene_id:2036|Hs108|chr20 (880 aa)
initn: 2640 init1: 2037 opt: 2116 Z-score: 1871.2 bits: 357.7 E(32554): 6.6e-98
Smith-Waterman score: 2286; 43.5% identity (63.0% similar) in 1086 aa overlap (1-1084:1-872)
10 20 30 40 50 60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
::::.: ::: : :: :: : .:.: : : . : : . .. : ..
CCDS58 MTTETGPDSEVKKAQEEAPQ-----QPEAAAAVTTPVTPAGHGHPE---ANSNEKHPSQQ
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
.. :: . .. .:. : : ::.... :: ..:: ::.:: :: :.: :::.:
CCDS58 DTRPAEQSLDM---EEKDYS--EADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDAS
60 70 80 90 100
130 140 150 160 170 180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
:: :.:::..::::::: ::::::::::::::::. ::..:::::::.::::::.::. :
CCDS58 EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPW
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
.:.:.:::::::::::.::::::::::::: ::..::::::::: ::::::.::.:::::
CCDS58 NFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
: .: ..:.::.:::::.:.:::....::::..:::::.:::.::::::::::::::::
CCDS58 DAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
::::::::..:::::::.::::::::::::::::::.:::::::.::::::::::.::::
CCDS58 HHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
:::::::::::.::::::::.::::::::. :: ::: ::..:::::::::::::::.::
CCDS58 STIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQAS
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEKKAEEERDE
::::::::.::::::::::::::::: .... ..:... . :. ..: :
CCDS58 ALIDRPAPFFERSSSKRYTMSRSLDG----AEFSRPASVSENH---DAGPDGDKRDEDGE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 EEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLP
.: ..:: : ..: : :.: . :.: : :.
CCDS58 SGGQRSEAEE--------GEVRTP---TKIKELKPEQE----TTP-----RHKQ------
470 480 490
550 560 570 580 590 600
pF1KA0 GYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLL
: : : : .:: .... . .. .. .:. :.: .:.
CCDS58 -------EFL--------DKP-------EDVLLKHQASINE----LKRTLKEPNS--KLI
500 510 520
610 620 630 640 650 660
pF1KA0 DDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPL
: . . ::.: : ::: : .
CCDS58 HRDR-----DWERERRLPSS-----PA-SPS-------------------PKGT------
530 540 550
670 680 690 700 710 720
pF1KA0 ALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQE
:. :. :.: ..:::.. : : ...: ..:::.:. .
CCDS58 --------PEKANERAGL----REGSEEKVKPPRP-RAPESDTGDEDQDQERDTVF----
560 570 580 590
730 740 750 760 770 780
pF1KA0 LEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLV
:. .. . .. ..:. . . ::. .: .: .... .. :: : .
CCDS58 LKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYH----------GSAFEDFSRSLPEL
600 610 620 630 640
790 800 810 820 830 840
pF1KA0 PEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPT
.. ..:. : :. :: .. :. : .. ::.::: :
CCDS58 DRDKSDSDTEGLL-----FS--------RDLNKGAPSQDD----------ESGGIEDSP-
650 660 670
850 860 870 880 890 900
pF1KA0 VHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEG
.: .: .. : .: : .: . .. . .
CCDS58 -------------------DR-----------GACSTPD---MPQFEPVKTETMTVSSLA
680 690 700
910 920 930 940 950 960
pF1KA0 AKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGS
... : :::. . ..: . : . ::.. : . : .. ::::: .
CCDS58 IRKKIEPE---AVLQTR--VSAMDNTQVDGSASVG-REFIATTP-----SITTETIS--T
710 720 730 740 750
970 980 990 1000 1010
pF1KA0 VSPGGVKLEISTKEVPVVHTETKTITYESSQVDP--GTDLEPGVLMSAQTITSETTSTTT
. ...: : : . .. .:.. : ...: : : :: :. :.:: ::.:
CCDS58 TMENSLK---SGKGAAAMIPGPQTVATEIRSLSPIIGKD----VLTSTYGATAETLSTST
760 770 780 790 800
1020 1030 1040 1050 1060 1070
pF1KA0 TTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKET
:::.:::::::.:::::::::.:::: :.:.::::: :::::: ::::: :::.::..::
CCDS58 TTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVTKAVVYRET
810 820 830 840 850 860
1080
pF1KA0 EITPEDGED
. .::.
CCDS58 DPSPEERDKKPQES
870 880
>>CCDS13271.1 EPB41L1 gene_id:2036|Hs108|chr20 (881 aa)
initn: 2630 init1: 2037 opt: 2116 Z-score: 1871.2 bits: 357.7 E(32554): 6.6e-98
Smith-Waterman score: 2296; 43.6% identity (63.1% similar) in 1086 aa overlap (1-1084:1-873)
10 20 30 40 50 60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
::::.: ::: : :: :: : .:.: : : . : : . .. : ..
CCDS13 MTTETGPDSEVKKAQEEAPQ-----QPEAAAAVTTPVTPAGHGHPE---ANSNEKHPSQQ
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
.. :: . .. .:. : : ::.... :: ..:: ::.:: :: :.: :::.:
CCDS13 DTRPAEQSLDM---EEKDYS--EADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDAS
60 70 80 90 100
130 140 150 160 170 180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
:: :.:::..::::::: ::::::::::::::::. ::..:::::::.::::::.::. :
CCDS13 EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPW
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
.:.:.:::::::::::.::::::::::::: ::..::::::::: ::::::.::.:::::
CCDS13 NFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
: .: ..:.::.:::::.:.:::....::::..:::::.:::.::::::::::::::::
CCDS13 DAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
::::::::..:::::::.::::::::::::::::::.:::::::.::::::::::.::::
CCDS13 HHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
:::::::::::.::::::::.::::::::. :: ::: ::..:::::::::::::::.::
CCDS13 STIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQAS
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEKKAEEERDE
::::::::.::::::::::::::::: .... ..:... . :. ..: :
CCDS13 ALIDRPAPFFERSSSKRYTMSRSLDG----AEFSRPASVSENH---DAGPDGDKRDEDGE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 EEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLP
.: ..:: : ..: : :.: . :.: : :.
CCDS13 SGGQRSEAEE--------GEVRTP---TKIKELKPEQE----TTP-----RHKQ------
470 480 490
550 560 570 580 590 600
pF1KA0 GYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLL
: : : : .:: .... . .. .. .:. :.: .:.
CCDS13 -------EFL--------DKP-------EDVLLKHQASINE----LKRTLKEPNS--KLI
500 510 520
610 620 630 640 650 660
pF1KA0 DDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPL
: . . ::.: : ::: : .
CCDS13 HRDR-----DWERERRLPSS-----PA-SPS-------------------PKGT------
530 540 550
670 680 690 700 710 720
pF1KA0 ALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQE
:. :. :.: ..:::.. : : ...: ..:::.:. .
CCDS13 --------PEKANERAGL----REGSEEKVKPPRP-RAPESDTGDEDQDQERDTVF----
560 570 580 590
730 740 750 760 770 780
pF1KA0 LEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLV
:. .. . .. ..:. . . ::. .: .: .... .. :: : .
CCDS13 LKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYH----------GSAFEDFSRSLPEL
600 610 620 630 640
790 800 810 820 830 840
pF1KA0 PEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPT
.. ..:. : :. :: .. :. : .. ::.::: :
CCDS13 DRDKSDSDTEGLL-----FS--------RDLNKGAPSQDD----------ESGGIEDSP-
650 660 670
850 860 870 880 890 900
pF1KA0 VHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEG
.: .: .. : .: : .: . .. . .
CCDS13 -------------------DR-----------GACSTPD---MPQFEPVKTETMTVSSLA
680 690 700
910 920 930 940 950 960
pF1KA0 AKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGS
... : ::: : ...: . .: . ::.. : . : .. ::::: .
CCDS13 IRKKIEPE---AVL-QTRVSAMDNTQQVDGSASVG-REFIATTP-----SITTETIS--T
710 720 730 740 750
970 980 990 1000 1010
pF1KA0 VSPGGVKLEISTKEVPVVHTETKTITYESSQVDP--GTDLEPGVLMSAQTITSETTSTTT
. ...: : : . .. .:.. : ...: : : :: :. :.:: ::.:
CCDS13 TMENSLK---SGKGAAAMIPGPQTVATEIRSLSPIIGKD----VLTSTYGATAETLSTST
760 770 780 790 800
1020 1030 1040 1050 1060 1070
pF1KA0 TTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKET
:::.:::::::.:::::::::.:::: :.:.::::: :::::: ::::: :::.::..::
CCDS13 TTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVTKAVVYRET
810 820 830 840 850 860
1080
pF1KA0 EITPEDGED
. .::.
CCDS13 DPSPEERDKKPQES
870 880
>>CCDS58770.1 EPB41L1 gene_id:2036|Hs108|chr20 (701 aa)
initn: 2519 init1: 2037 opt: 2057 Z-score: 1820.6 bits: 348.0 E(32554): 4.4e-95
Smith-Waterman score: 2095; 63.8% identity (82.2% similar) in 506 aa overlap (72-571:25-515)
50 60 70 80 90
pF1KA0 QQALEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQL---EDDKLSQKSSSSKLSR
:..:.:.... : : ::.... :: ..
CCDS58 MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQK
10 20 30 40 50
100 110 120 130 140 150
pF1KA0 SPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDA
:: ::.:: :: :.: :::.::: :.:::..::::::: ::::::::::::::::. ::
CCDS58 SPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDA
60 70 80 90 100 110
160 170 180 190 200 210
pF1KA0 ENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRL
..:::::::.::::::.::. :.:.:.:::::::::::.::::::::::::: ::..:::
CCDS58 DSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRL
120 130 140 150 160 170
220 230 240 250 260 270
pF1KA0 PCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMT
:::::: ::::::.::.:::::: .: ..:.::.:::::.:.:::....::::..::::
CCDS58 PCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMT
180 190 200 210 220 230
280 290 300 310 320 330
pF1KA0 PAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVL
:.:::.::::::::::::::::::::::::..:::::::.::::::::::::::::::.:
CCDS58 PGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKIL
240 250 260 270 280 290
340 350 360 370 380 390
pF1KA0 KISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKK
::::::.::::::::::.:::::::::::::::.::::::::.::::::::. :: :::
CCDS58 KISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKG
300 310 320 330 340 350
400 410 420 430 440 450
pF1KA0 FLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKG
::..:::::::::::::::.::::::::::.::::::::::::::::: .... .
CCDS58 FLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG----AEFSRPAS
360 370 380 390 400 410
460 470 480 490 500 510
pF1KA0 ISQTNLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPST
.:... . :. ..: : .: ..:: . .: : : . : .
CCDS58 VSENH---DAGPDGDKRDEDGESGGQRSEAEE----GEVRTPTKIKELKFLDKPEDVLLK
420 430 440 450 460
520 530 540 550 560 570
pF1KA0 HCAPTSPTELRRRCKENDCKLPGYEPS--RAEHLPGEPALDSDGP-GRPYLGDQDVAFSY
: : : .::.: :: . :: . . : ..::. :: : .: : : ... :
CCDS58 HQA--SINELKRTLKEPNSKLIHRDRDWERERRLPSSPA--SPSPKGTPEKANEPVKTET
470 480 490 500 510
580 590 600 610 620 630
pF1KA0 RQQTGKGTTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPC
CCDS58 MTVSSLAIRKKIEPEAVLQTRVSAMDNTQQVDGSASVGREFIATTPSITTETISTTMENS
520 530 540 550 560 570
>--
initn: 408 init1: 370 opt: 390 Z-score: 347.9 bits: 75.5 E(32554): 4.6e-13
Smith-Waterman score: 390; 46.6% identity (69.3% similar) in 176 aa overlap (911-1084:534-693)
890 900 910 920 930 940
pF1KA0 AAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETL
.::: : ...: . .: . ::.. : .
CCDS58 PKGTPEKANEPVKTETMTVSSLAIRKKIEPEAVL-QTRVSAMDNTQQVDGSASVG-REFI
510 520 530 540 550 560
950 960 970 980 990
pF1KA0 EQKPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDP--GTDL
: .. ::::: .. ...: : : . .. .:.. : ...: : :
CCDS58 ATTP-----SITTETIS--TTMENSLK---SGKGAAAMIPGPQTVATEIRSLSPIIGKD-
570 580 590 600 610
1000 1010 1020 1030 1040 1050
pF1KA0 EPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIK
:: :. :.:: ::.::::.:::::::.:::::::::.:::: :.:.::::: :::
CCDS58 ---VLTSTYGATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIK
620 630 640 650 660
1060 1070 1080
pF1KA0 EAKEQHPDMSVTKVVVHKETEITPEDGED
::: ::::: :::.::..::. .::.
CCDS58 EAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES
670 680 690 700
>>CCDS13272.1 EPB41L1 gene_id:2036|Hs108|chr20 (779 aa)
initn: 2508 init1: 2037 opt: 2051 Z-score: 1814.6 bits: 347.0 E(32554): 9.4e-95
Smith-Waterman score: 2143; 43.4% identity (60.7% similar) in 1004 aa overlap (83-1084:8-771)
60 70 80 90 100 110
pF1KA0 AHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQC
: : ::.... :: ..:: ::.:: :: :
CCDS13 MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAIC
10 20 30
120 130 140 150 160 170
pF1KA0 KVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIK
.: :::.::: :.:::..::::::: ::::::::::::::::. ::..:::::::.::::
CCDS13 RVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIK
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 KQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYT
::.::. :.:.:.:::::::::::.::::::::::::: ::..::::::::: ::::::.
CCDS13 KQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 VQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKK
::.:::::: .: ..:.::.:::::.:.:::....::::..:::::.:::.::::::::
CCDS13 VQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKK
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 LSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIR
::::::::::::::::..:::::::.::::::::::::::::::.:::::::.:::::::
CCDS13 LSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIR
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 PGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRT
:::.:::::::::::::::.::::::::.::::::::. :: ::: ::..::::::::::
CCDS13 PGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRT
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA0 QAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEK
:::::.::::::::::.::::::::::::::::: .... ..:... . :.
CCDS13 QAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG----AEFSRPASVSENH---DAGPDG
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA0 KAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRC
..: : .: ..:: . .: : : . : . : : : .::.:
CCDS13 DKRDEDGESGGQRSEAEE----GEVRTPTKIKELKFLDKPEDVLLKHQA--SINELKRTL
400 410 420 430 440
540 550 560 570 580 590
pF1KA0 KENDCKLPGYEPS--RAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSL
:: . :: . . : ..::. :: : .: :::
CCDS13 KEPNSKLIHRDRDWERERRLPSSPA--SPSP-------------------KGT-------
450 460 470
600 610 620 630 640 650
pF1KA0 QLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSV
CCDS13 ------------------------------------------------------------
660 670 680 690 700 710
pF1KA0 PYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQ
:. :. :.: ..:::.. : : ...: ..::
CCDS13 ------------------PEKANERAGL----REGSEEKVKPPRP-RAPESDTGDEDQDQ
480 490 500 510
720 730 740 750 760 770
pF1KA0 EEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQ
:.:. . :. .. . .. ..:. . . ::. .: .: .... ..
CCDS13 ERDTVF----LKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYH----------GSAF
520 530 540 550
780 790 800 810 820 830
pF1KA0 EDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKT
:: : . .. ..:. : :. :: . :..
CCDS13 EDFSRSLPELDRDKSDSDTEGLL-----FSRDLNKGAPSQ------------------DD
560 570 580 590
840 850 860 870 880 890
pF1KA0 ESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIK
::.::: : .: .: .. : .: : .:
CCDS13 ESGGIEDSP--------------------DR-----------GACSTPD---MPQFEPVK
600 610 620
900 910 920 930 940 950
pF1KA0 GKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESST
. .. . . ... : :::. . .: . ::.. . . . .. :. :
CCDS13 TETMTVSSLAIRKKIEPE---AVLQTRVSAMDNT--QENSLKSGKGAAAMIPGPQ----T
630 640 650 660 670
960 970 980 990 1000 1010
pF1KA0 VKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTIT
: :: :.. :.. : : :: :. :
CCDS13 VATEIRSLS----------------PII----------------GKD----VLTSTYGAT
680 690
1020 1030 1040 1050 1060 1070
pF1KA0 SETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVT
.:: ::.::::.:::::::.:::::::::.:::: :.:.::::: :::::: ::::: ::
CCDS13 AETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVT
700 710 720 730 740 750
1080
pF1KA0 KVVVHKETEITPEDGED
:.::..::. .::.
CCDS13 KAVVYRETDPSPEERDKKPQES
760 770
>>CCDS59037.1 EPB41L2 gene_id:2037|Hs108|chr6 (747 aa)
initn: 2409 init1: 1668 opt: 1943 Z-score: 1719.5 bits: 329.4 E(32554): 1.9e-89
Smith-Waterman score: 1947; 58.6% identity (80.1% similar) in 517 aa overlap (15-517:115-626)
10 20 30 40
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQA
.: :.: :.: : . . .: . ..
CCDS59 QKSYTLVVAKDGGDKKEPTQAVVEEQVLDKEEPLPEEQRQAKGDA-EEMAQKKQEIKVEV
90 100 110 120 130 140
50 60 70 80 90
pF1KA0 LEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKL--------SQKSSSSKL
:. ... . : .: . :.... .. . .. ..::: ... ....:
CCDS59 KEEKPSVSKEEKPSVSKVEMQPTELVSKE-REEKVKETQEDKLEGGAAKRETKEVQTNEL
150 160 170 180 190 200
100 110 120 130 140 150
pF1KA0 S--RSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLT
. .. :..:: :..:::: ::::.::.::.::...::::::::::::::::::::::
CCDS59 KAEKASQKVTKKTKTVQCKVTLLDGTEYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLL
210 220 230 240 250 260
160 170 180 190 200 210
pF1KA0 YRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIV
.... .::::::::::::.:.:. : :.::::::::::.::.::::::.::::::.::.
CCDS59 FQESPEQKNWLDPAKEIKRQLRNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIA
270 280 290 300 310 320
220 230 240 250 260 270
pF1KA0 SGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSH
:::::::::: :::::::.:.:::::::.: :: .:::.:::..:::::.:: ::::.:
CCDS59 SGRLPCSFVTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTH
330 340 350 360 370 380
280 290 300 310 320 330
pF1KA0 RGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAW
::..::.:. .::::::.:::::::::::::::::.: :::::.:::::.::::::::::
CCDS59 RGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAW
390 400 410 420 430 440
340 350 360 370 380 390
pF1KA0 PKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEA
::.:::::::.:::::.::.:.::::::::::::::::::::::::::::::.::. ::
CCDS59 PKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQ
450 460 470 480 490 500
400 410 420 430 440 450
pF1KA0 PPK-KFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGE-VGTGQ
::: ::::::::::::::::::::.::.:::::::.:::.:::: .:::::: .:. .
CCDS59 PPKAKFLTLGSKFRYSGRTQAQTRQASTLIDRPAPHFERTSSKR--VSRSLDGAPIGVMD
510 520 530 540 550 560
460 470 480 490 500 510
pF1KA0 YATTKGI-SQTNLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRH-EGKSPGLGTDS
. : . . .. :.. : . .. : ::. . : .. ::: : . :.
CCDS59 QSLMKDFPGAAGEISAYGP-GLVSIAVVQDGDGRREVRSPTKAPHLQLIEGKPPVVKTEM
570 580 590 600 610
520 530 540 550 560 570
pF1KA0 CPLSPPSTHCAPTSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQD
.: :
CCDS59 VTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGAGGDSGTLLTAQTITSESVSTTT
620 630 640 650 660 670
>--
initn: 636 init1: 584 opt: 599 Z-score: 532.1 bits: 109.7 E(32554): 2.5e-23
Smith-Waterman score: 599; 79.3% identity (94.2% similar) in 121 aa overlap (967-1087:628-747)
940 950 960 970 980 990
pF1KA0 SETLEQKPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGT
. ::::::::.:.:::::::::: :.: :.
CCDS59 SPTKAPHLQLIEGKPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGA
600 610 620 630 640 650
1000 1010 1020 1030 1040 1050
pF1KA0 DLEPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQA
. :.:..:::::::..::::::::::::::::::::::::::::::.:::::::::::
CCDS59 GGDSGTLLTAQTITSESVSTTTTTHITKTVKGGISETRIEKRIVITGDGDIDHDQALAQA
660 670 680 690 700 710
1060 1070 1080
pF1KA0 IKEAKEQHPDMSVTKVVVHKETEITPEDGED
:.::.:::::::::.::::::::.. :.:::
CCDS59 IREAREQHPDMSVTRVVVHKETELA-EEGED
720 730 740
1087 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:38:11 2016 done: Thu Nov 3 10:38:12 2016
Total Scan time: 5.240 Total Display time: 0.420
Function used was FASTA [36.3.4 Apr, 2011]