Result of FASTA (ccds) for
pFN21AA0068
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0068, 1253 aa
1>>>pF1KA0068 1253 - 1253 aa - 1253 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7388+/-0.00118; mu= 20.0664+/- 0.072
mean_var=67.0446+/-13.507, 0's: 0 Z-trim(101.1): 29 B-trim: 132 in 1/49
Lambda= 0.156636
statistics sampled from 6387 (6398) to 6387 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.541), E-opt: 0.2 (0.197), width: 16
Scan time: 4.500
The best scores are: opt bits E(32554)
CCDS73696.1 CYFIP1 gene_id:23191|Hs108|chr15 (1253) 8354 1897.8 0
CCDS75364.1 CYFIP2 gene_id:26999|Hs108|chr5 (1253) 7477 1699.6 0
CCDS78078.1 CYFIP2 gene_id:26999|Hs108|chr5 (1227) 6883 1565.4 0
CCDS73695.1 CYFIP1 gene_id:23191|Hs108|chr15 ( 822) 4676 1066.6 0
CCDS78077.1 CYFIP2 gene_id:26999|Hs108|chr5 (1278) 4101 936.7 0
>>CCDS73696.1 CYFIP1 gene_id:23191|Hs108|chr15 (1253 aa)
initn: 8354 init1: 8354 opt: 8354 Z-score: 10190.8 bits: 1897.8 E(32554): 0
Smith-Waterman score: 8354; 100.0% identity (100.0% similar) in 1253 aa overlap (1-1253:1-1253)
10 20 30 40 50 60
pF1KA0 MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 IVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 QLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 DKYSNKDCPDSAEEYERATRYNYTSEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DKYSNKDCPDSAEEYERATRYNYTSEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 YAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 YAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 FYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 MEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 ELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDAMFREANHNVSAPYGRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDAMFREANHNVSAPYGRIT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 IYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKIC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 DLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 LTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 PVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 PVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVP
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250
pF1KA0 LKKMVERIRKFQILNDEIITILDKYLKSGDGEGTPVEHVRCFQPPIHQSLASS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LKKMVERIRKFQILNDEIITILDKYLKSGDGEGTPVEHVRCFQPPIHQSLASS
1210 1220 1230 1240 1250
>>CCDS75364.1 CYFIP2 gene_id:26999|Hs108|chr5 (1253 aa)
initn: 7474 init1: 5150 opt: 7477 Z-score: 9119.8 bits: 1699.6 E(32554): 0
Smith-Waterman score: 7477; 87.6% identity (96.8% similar) in 1253 aa overlap (1-1253:1-1252)
10 20 30 40 50 60
pF1KA0 MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYI
:...:::::::::::::::::::::::::::::::..:: ::.:::::::::::::::::
CCDS75 MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS75 EQATVHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCS
:::.::::::.::::::.::.:::::::::::::::::.:::::::::::::::::::::
CCDS75 KLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLAD
::::::::::::::::::::::::::::::::::::::.::: :.:::::: ::::::::
CCDS75 VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 IVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFK
:::.:::::::.::::::::::::::::::::::::.::::::::::::::::::::.::
CCDS75 IVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFI
::::::::::::::::::::::::::::::.::::.:. ::::::::::.:::.::.:::
CCDS75 QLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPT
:::::::::::::::: ..::.: :::.::::::.::::::.:::::::::::::::::
CCDS75 SELARYSNSEVVTGSG-LDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPT
370 380 390 400 410
430 440 450 460 470 480
pF1KA0 DKYSNKDCPDSAEEYERATRYNYTSEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTV
::. ::::: .:::::::::::::::::::.::::::::::::::::::::::.:::.:.
CCDS75 DKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTI
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 YAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPK
:::::::.:::::::::::..:::::. :::::::::.:::: :.:: ::: ::::::::
CCDS75 YAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 SGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESF
.:::::::::::::::::::::::::::::::::::::::::::.:: .: :: ::..::
CCDS75 GGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSF
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 FYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASM
:.:::.:.::.:::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS75 FFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSM
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 MEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGS
:::::: ::::::::.::::.:.::::::::::::::::::::::::::::::::.::::
CCDS75 MEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 LLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSL
.:::::.:.:::: :. : :::::::::::::::::::::::::::::::.::::::::
CCDS75 VLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 ELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDAMFREANHNVSAPYGRIT
. ::.:::::::::::::. ::::::.::.:: ...:::.::::::::::::::::::::
CCDS75 DQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRIT
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA0 LHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSS
::::::::.::::::::::::::::::..::.:: :::: :.:: ::.::: ::.:::
CCDS75 LHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSH
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA0 IYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKIC
::.:::::::::::..:::::::::::::::::::.::::::::::::::::.:::::::
CCDS75 IYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKIC
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 RLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVC
:::::::::::::::::::::::.::::::: ::.::::::::::::::::.:: ::::
CCDS75 RLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVC
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 DLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDL
:::::::::::::::..::::::...:::::.::::::::::::::::::::::::::::
CCDS75 DLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDL
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA0 LTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCI
::::::::::::::::::::::.:.::::::: :.:::::::::::::::::::::::::
CCDS75 LTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCI
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA0 PVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVP
::::.:::.::::::::.:::: ::::::::::: ..::::::::::..:::::::::::
CCDS75 PVGTNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVP
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250
pF1KA0 LKKMVERIRKFQILNDEIITILDKYLKSGDGEGTPVEHVRCFQPPIHQSLASS
::::..::::.::::.:...::.::.:: . ... ::::::::::::::::..
CCDS75 LKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC
1200 1210 1220 1230 1240 1250
>>CCDS78078.1 CYFIP2 gene_id:26999|Hs108|chr5 (1227 aa)
initn: 7286 init1: 5150 opt: 6883 Z-score: 8394.5 bits: 1565.4 E(32554): 0
Smith-Waterman score: 7241; 85.6% identity (94.7% similar) in 1253 aa overlap (1-1253:1-1226)
10 20 30 40 50 60
pF1KA0 MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYI
:...:::::::::::::::::::::::::::::::..:: ::.:::::::::::::::::
CCDS78 MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVT
::::::::: :::::::::::::::::::::::::
CCDS78 EQATVHSSM--------------------------VKCNEQPNRVEIYEKTVEVLEPEVT
70 80 90
130 140 150 160 170 180
pF1KA0 KLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCS
:::.::::::.::::::.::.:::::::::::::::::.:::::::::::::::::::::
CCDS78 KLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLAD
::::::::::::::::::::::::::::::::::::::.::: :.:::::: ::::::::
CCDS78 VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLAD
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 IVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFK
:::.:::::::.::::::::::::::::::::::::.::::::::::::::::::::.::
CCDS78 IVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFK
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 QLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFI
::::::::::::::::::::::::::::::.::::.:. ::::::::::.:::.::.:::
CCDS78 QLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 SELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPT
:::::::::::::::: ..::.: :::.::::::.::::::.:::::::::::::::::
CCDS78 SELARYSNSEVVTGSG-LDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 DKYSNKDCPDSAEEYERATRYNYTSEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTV
::. ::::: .:::::::::::::::::::.::::::::::::::::::::::.:::.:.
CCDS78 DKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTI
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 YAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPK
:::::::.:::::::::::..:::::. :::::::::.:::: :.:: ::: ::::::::
CCDS78 YAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPK
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 SGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESF
.:::::::::::::::::::::::::::::::::::::::::::.:: .: :: ::..::
CCDS78 GGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSF
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 FYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASM
:.:::.:.::.:::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS78 FFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSM
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 MEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGS
:::::: ::::::::.::::.:.::::::::::::::::::::::::::::::::.::::
CCDS78 MEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGS
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 LLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSL
.:::::.:.:::: :. : :::::::::::::::::::::::::::::::.::::::::
CCDS78 VLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 ELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDAMFREANHNVSAPYGRIT
. ::.:::::::::::::. ::::::.::.:: ...:::.::::::::::::::::::::
CCDS78 DQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRIT
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 LHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSS
::::::::.::::::::::::::::::..::.:: :::: :.:: ::.::: ::.:::
CCDS78 LHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSH
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 IYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKIC
::.:::::::::::..:::::::::::::::::::.::::::::::::::::.:::::::
CCDS78 IYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKIC
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 RLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVC
:::::::::::::::::::::::.::::::: ::.::::::::::::::::.:: ::::
CCDS78 RLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVC
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 DLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDL
:::::::::::::::..::::::...:::::.::::::::::::::::::::::::::::
CCDS78 DLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDL
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 LTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCI
::::::::::::::::::::::.:.::::::: :.:::::::::::::::::::::::::
CCDS78 LTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCI
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 PVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVP
::::.:::.::::::::.:::: ::::::::::: ..::::::::::..:::::::::::
CCDS78 PVGTNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVP
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250
pF1KA0 LKKMVERIRKFQILNDEIITILDKYLKSGDGEGTPVEHVRCFQPPIHQSLASS
::::..::::.::::.:...::.::.:: . ... ::::::::::::::::..
CCDS78 LKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC
1180 1190 1200 1210 1220
>>CCDS73695.1 CYFIP1 gene_id:23191|Hs108|chr15 (822 aa)
initn: 4704 init1: 4674 opt: 4676 Z-score: 5701.9 bits: 1066.6 E(32554): 0
Smith-Waterman score: 4676; 99.6% identity (99.6% similar) in 700 aa overlap (554-1253:123-822)
530 540 550 560 570 580
pF1KA0 GHEPFNDPALRGEKDPKSGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSS
: ::::::::::::::::::::::::::
CCDS73 QGVAEQSFSHGLFEFGITNVPCIFSPPQMFPWIIQLYMVRTMLESLIADKSGSKKTLRSS
100 110 120 130 140 150
590 600 610 620 630 640
pF1KA0 LEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMS
160 170 180 190 200 210
650 660 670 680 690 700
pF1KA0 MPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFV
220 230 240 250 260 270
710 720 730 740 750 760
pF1KA0 YKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 YKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSID
280 290 300 310 320 330
770 780 790 800 810 820
pF1KA0 LNRLITQRVSAAMYKSLELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LNRLITQRVSAAMYKSLELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDA
340 350 360 370 380 390
830 840 850 860 870 880
pF1KA0 MFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNA
400 410 420 430 440 450
890 900 910 920 930 940
pF1KA0 QPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 QPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQG
460 470 480 490 500 510
950 960 970 980 990 1000
pF1KA0 TILQYVKTLMEVMPKICRLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TILQYVKTLMEVMPKICRLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNA
520 530 540 550 560 570
1010 1020 1030 1040 1050 1060
pF1KA0 ILFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ILFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLI
580 590 600 610 620 630
1070 1080 1090 1100 1110 1120
pF1KA0 ERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDE
640 650 660 670 680 690
1130 1140 1150 1160 1170 1180
pF1KA0 CVEFHRLWSAMQFVYCIPVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 CVEFHRLWSAMQFVYCIPVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHL
700 710 720 730 740 750
1190 1200 1210 1220 1230 1240
pF1KA0 LKVQKHDGKDEIIKNVPLKKMVERIRKFQILNDEIITILDKYLKSGDGEGTPVEHVRCFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LKVQKHDGKDEIIKNVPLKKMVERIRKFQILNDEIITILDKYLKSGDGEGTPVEHVRCFQ
760 770 780 790 800 810
1250
pF1KA0 PPIHQSLASS
::::::::::
CCDS73 PPIHQSLASS
820
>>CCDS78077.1 CYFIP2 gene_id:26999|Hs108|chr5 (1278 aa)
initn: 7463 init1: 4101 opt: 4101 Z-score: 4996.5 bits: 936.7 E(32554): 0
Smith-Waterman score: 7417; 85.9% identity (94.9% similar) in 1278 aa overlap (1-1253:1-1277)
10 20 30 40 50 60
pF1KA0 MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYI
:...:::::::::::::::::::::::::::::::..:: ::.:::::::::::::::::
CCDS78 MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVT
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS78 EQATVHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCS
:::.::::::.::::::.::.:::::::::::::::::.:::::::::::::::::::::
CCDS78 KLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLAD
::::::::::::::::::::::::::::::::::::::.::: :.:::::: ::::::::
CCDS78 VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 IVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFK
:::.:::::::.::::::::::::::::::::::::.::::::::::::::::::::.::
CCDS78 IVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFI
::::::::::::::::::::::::::::::.::::.:. ::::::::::.:::.::.:::
CCDS78 QLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPT
:::::::::::::::: ..::.: :::.::::::.::::::.:::::::::::::::::
CCDS78 SELARYSNSEVVTGSG-LDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPT
370 380 390 400 410
430 440 450 460 470 480
pF1KA0 DKYSNKDCPDSAEEYERATRYNYTSEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTV
::. ::::: .:::::::::::::::::::.::::::::::::::::::::::.:::.:.
CCDS78 DKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTI
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 YAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPK
:::::::.:::::::::::..:::::. :::::::::.:::: :.:: ::: ::::::::
CCDS78 YAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPK
480 490 500 510 520 530
550 560 570
pF1KA0 SGFDIKVPRRAVGPSSTQ-------------------------LYMVRTMLESLIADKSG
.::::::::::::::::: :::::::::::::::::
CCDS78 GGFDIKVPRRAVGPSSTQACQWSPRALFHPTGGTQGRRGCRSLLYMVRTMLESLIADKSG
540 550 560 570 580 590
580 590 600 610 620 630
pF1KA0 SKKTLRSSLEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRR
:::::::::.:: .: :: ::..:::.:::.:.::.::::::::::::::::::::::::
CCDS78 SKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRR
600 610 620 630 640 650
640 650 660 670 680 690
pF1KA0 IQFPIEMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEV
:::::::::::::::::::::: :::::::: ::::::::.::::.:.::::::::::::
CCDS78 IQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEV
660 670 680 690 700 710
700 710 720 730 740 750
pF1KA0 NLCFDQFVYKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHV
::::::::::::::::::::.::::.:::::.:.:::: :. : :::::::::::::::
CCDS78 NLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHV
720 730 740 750 760 770
760 770 780 790 800 810
pF1KA0 QLLGRSIDLNRLITQRVSAAMYKSLELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRY
::::::::::::::::.::::::::. ::.:::::::::::::. ::::::.::.:: ..
CCDS78 QLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKH
780 790 800 810 820 830
820 830 840 850 860 870
pF1KA0 LTLDGFDAMFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEF
.:::.::::::::::::::::::::::::::::.::::::::::::::::::..::.::
CCDS78 MTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEP
840 850 860 870 880 890
880 890 900 910 920 930
pF1KA0 QRDKQPNAQPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLK
:::: :.:: ::.::: ::.::: ::.:::::::::::..:::::::::::::::::::
CCDS78 QRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLK
900 910 920 930 940 950
940 950 960 970 980 990
pF1KA0 VVKSLLQGTILQYVKTLMEVMPKICRLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQ
.::::::::::::::::.::::::::::::::::::::::::::::::.::::::: ::
CCDS78 IVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQ
960 970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KA0 NLREVGNAILFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYA
.::::::::::::::::.:: :::::::::::::::::::..::::::...:::::.:::
CCDS78 SLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYA
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090 1100 1110
pF1KA0 PLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPS
:::::::::::::::::::::::::::::::::::::::::::::::.:.::::::: :.
CCDS78 PLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPT
1080 1090 1100 1110 1120 1130
1120 1130 1140 1150 1160 1170
pF1KA0 NGVMHVDECVEFHRLWSAMQFVYCIPVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFA
:::::::::::::::::::::::::::::.:::.::::::::.:::: :::::::::::
CCDS78 NGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFD
1140 1150 1160 1170 1180 1190
1180 1190 1200 1210 1220 1230
pF1KA0 VLDFCYHLLKVQKHDGKDEIIKNVPLKKMVERIRKFQILNDEIITILDKYLKSGDGEGTP
..::::::::::..:::::::::::::::..::::.::::.:...::.::.:: . ...
CCDS78 LFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSST
1200 1210 1220 1230 1240 1250
1240 1250
pF1KA0 VEHVRCFQPPIHQSLASS
::::::::::::::::..
CCDS78 VEHVRCFQPPIHQSLATTC
1260 1270
1253 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:07:44 2016 done: Thu Nov 3 09:07:45 2016
Total Scan time: 4.500 Total Display time: 0.350
Function used was FASTA [36.3.4 Apr, 2011]