Result of FASTA (omim) for
pFN21ASDA0224
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0224, 1227 aa
1>>>pF1KSDA0224 1227 - 1227 aa - 1227 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5297+/-0.000492; mu= 8.5578+/- 0.031
mean_var=284.6710+/-57.721, 0's: 0 Z-trim(116.5): 197 B-trim: 126 in 1/56
Lambda= 0.076016
statistics sampled from 27474 (27686) to 27474 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.325), width: 16
Scan time: 14.540
The best scores are: opt bits E(85289)
XP_011521786 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1227) 8205 915.2 0
NP_054722 (OMIM: 605584) pre-mRNA-splicing factor (1227) 8205 915.2 0
XP_011521787 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1227) 8205 915.2 0
XP_005256326 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1192) 6892 771.2 0
XP_016879402 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1192) 6892 771.2 0
NP_001309146 (OMIM: 600396) ATP-dependent RNA heli (1129) 2545 294.4 2.7e-78
NP_004932 (OMIM: 600396) ATP-dependent RNA helicas (1220) 2545 294.5 2.9e-78
NP_001309150 (OMIM: 600396) ATP-dependent RNA heli (1218) 2537 293.6 5.3e-78
NP_001309145 (OMIM: 600396) ATP-dependent RNA heli ( 945) 2481 287.3 3.1e-76
NP_001309148 (OMIM: 600396) ATP-dependent RNA heli (1169) 2374 275.7 1.2e-72
NP_001289552 (OMIM: 600396) ATP-dependent RNA heli (1181) 2374 275.7 1.2e-72
NP_001309149 (OMIM: 600396) ATP-dependent RNA heli (1152) 2371 275.4 1.5e-72
NP_001309147 (OMIM: 600396) ATP-dependent RNA heli (1179) 2366 274.8 2.3e-72
NP_001157711 (OMIM: 603405) putative pre-mRNA-spli ( 981) 2338 271.7 1.7e-71
NP_003578 (OMIM: 603405) putative pre-mRNA-splicin (1041) 2331 270.9 3e-71
XP_011513241 (OMIM: 603405) PREDICTED: putative pr ( 742) 2316 269.1 7.5e-71
XP_011513240 (OMIM: 603405) PREDICTED: putative pr ( 742) 2316 269.1 7.5e-71
NP_001349 (OMIM: 603403) pre-mRNA-splicing factor ( 795) 1856 218.7 1.2e-55
XP_011513242 (OMIM: 603405) PREDICTED: putative pr ( 560) 1768 208.9 7.7e-53
XP_011513243 (OMIM: 603405) PREDICTED: putative pr ( 524) 1764 208.4 1e-52
NP_001186628 (OMIM: 614405) putative ATP-dependent ( 534) 1283 155.7 7.7e-37
NP_064547 (OMIM: 614405) putative ATP-dependent RN ( 707) 1257 153.0 6.7e-36
XP_011525852 (OMIM: 615475) PREDICTED: probable AT (1143) 1155 142.0 2.1e-32
XP_005259500 (OMIM: 615475) PREDICTED: probable AT (1143) 1155 142.0 2.1e-32
XP_011525853 (OMIM: 615475) PREDICTED: probable AT (1143) 1155 142.0 2.1e-32
NP_055496 (OMIM: 615475) probable ATP-dependent RN (1143) 1155 142.0 2.1e-32
XP_016871893 (OMIM: 607960) PREDICTED: putative pr ( 743) 1100 135.8 1e-30
NP_060650 (OMIM: 607960) putative pre-mRNA-splicin ( 743) 1100 135.8 1e-30
XP_016871894 (OMIM: 607960) PREDICTED: putative pr ( 743) 1100 135.8 1e-30
XP_006722146 (OMIM: 607570) PREDICTED: probable AT ( 752) 998 124.6 2.5e-27
XP_016880572 (OMIM: 607570) PREDICTED: probable AT ( 640) 847 107.9 2.1e-22
XP_016880571 (OMIM: 607570) PREDICTED: probable AT ( 640) 847 107.9 2.1e-22
XP_011523556 (OMIM: 607570) PREDICTED: probable AT ( 680) 847 108.0 2.2e-22
NP_001159773 (OMIM: 607570) probable ATP-dependent ( 702) 847 108.0 2.3e-22
XP_016880569 (OMIM: 607570) PREDICTED: probable AT ( 723) 847 108.0 2.3e-22
NP_078888 (OMIM: 607570) probable ATP-dependent RN ( 779) 847 108.0 2.4e-22
XP_016880366 (OMIM: 614405) PREDICTED: putative AT ( 279) 694 90.7 1.4e-17
XP_011523555 (OMIM: 607570) PREDICTED: probable AT ( 718) 693 91.1 2.8e-17
NP_065916 (OMIM: 612767) ATP-dependent RNA helicas (1008) 615 82.7 1.3e-14
NP_001348 (OMIM: 603115) ATP-dependent RNA helicas (1270) 568 77.7 5.4e-13
XP_016880570 (OMIM: 607570) PREDICTED: probable AT ( 653) 560 76.5 6.5e-13
NP_001107869 (OMIM: 612767) ATP-dependent RNA heli ( 994) 536 74.1 5.3e-12
XP_016865224 (OMIM: 616530) PREDICTED: probable AT ( 971) 507 70.9 4.7e-11
NP_001332905 (OMIM: 616530) probable ATP-dependent (1130) 507 70.9 5.2e-11
XP_016865222 (OMIM: 616530) PREDICTED: probable AT (1139) 507 70.9 5.2e-11
XP_011541888 (OMIM: 616530) PREDICTED: probable AT (1162) 507 71.0 5.3e-11
NP_001332904 (OMIM: 616530) probable ATP-dependent (1268) 507 71.0 5.6e-11
XP_016865220 (OMIM: 616530) PREDICTED: probable AT (1277) 507 71.0 5.6e-11
XP_011541884 (OMIM: 616530) PREDICTED: probable AT (1406) 507 71.1 6e-11
NP_073739 (OMIM: 616530) probable ATP-dependent RN (1430) 507 71.1 6.1e-11
>>XP_011521786 (OMIM: 605584) PREDICTED: pre-mRNA-splici (1227 aa)
initn: 8205 init1: 8205 opt: 8205 Z-score: 4880.8 bits: 915.2 E(85289): 0
Smith-Waterman score: 8205; 99.9% identity (100.0% similar) in 1227 aa overlap (1-1227:1-1227)
10 20 30 40 50 60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
1150 1160 1170 1180 1190 1200
1210 1220
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
::::::::::::::::.::::::::::
XP_011 STKIYTPGRKEQGEPMTPRRTPARFGL
1210 1220
>>NP_054722 (OMIM: 605584) pre-mRNA-splicing factor ATP- (1227 aa)
initn: 8205 init1: 8205 opt: 8205 Z-score: 4880.8 bits: 915.2 E(85289): 0
Smith-Waterman score: 8205; 99.9% identity (100.0% similar) in 1227 aa overlap (1-1227:1-1227)
10 20 30 40 50 60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
1150 1160 1170 1180 1190 1200
1210 1220
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
::::::::::::::::.::::::::::
NP_054 STKIYTPGRKEQGEPMTPRRTPARFGL
1210 1220
>>XP_011521787 (OMIM: 605584) PREDICTED: pre-mRNA-splici (1227 aa)
initn: 8205 init1: 8205 opt: 8205 Z-score: 4880.8 bits: 915.2 E(85289): 0
Smith-Waterman score: 8205; 99.9% identity (100.0% similar) in 1227 aa overlap (1-1227:1-1227)
10 20 30 40 50 60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
1150 1160 1170 1180 1190 1200
1210 1220
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
::::::::::::::::.::::::::::
XP_011 STKIYTPGRKEQGEPMTPRRTPARFGL
1210 1220
>>XP_005256326 (OMIM: 605584) PREDICTED: pre-mRNA-splici (1192 aa)
initn: 6825 init1: 6825 opt: 6892 Z-score: 4102.7 bits: 771.2 E(85289): 0
Smith-Waterman score: 7882; 97.1% identity (97.1% similar) in 1227 aa overlap (1-1227:1-1192)
10 20 30 40 50 60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD---------
130 140 150 160 170
190 200 210 220 230 240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
::::::::::::::::::::::::::::::::::
XP_005 --------------------------AATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
180 190 200
250 260 270 280 290 300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
570 580 590 600 610 620
670 680 690 700 710 720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
630 640 650 660 670 680
730 740 750 760 770 780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
690 700 710 720 730 740
790 800 810 820 830 840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
750 760 770 780 790 800
850 860 870 880 890 900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
810 820 830 840 850 860
910 920 930 940 950 960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
1110 1120 1130 1140 1150 1160
1210 1220
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
::::::::::::::::.::::::::::
XP_005 STKIYTPGRKEQGEPMTPRRTPARFGL
1170 1180 1190
>>XP_016879402 (OMIM: 605584) PREDICTED: pre-mRNA-splici (1192 aa)
initn: 6825 init1: 6825 opt: 6892 Z-score: 4102.7 bits: 771.2 E(85289): 0
Smith-Waterman score: 7882; 97.1% identity (97.1% similar) in 1227 aa overlap (1-1227:1-1192)
10 20 30 40 50 60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD---------
130 140 150 160 170
190 200 210 220 230 240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
::::::::::::::::::::::::::::::::::
XP_016 --------------------------AATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
180 190 200
250 260 270 280 290 300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
570 580 590 600 610 620
670 680 690 700 710 720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
630 640 650 660 670 680
730 740 750 760 770 780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
690 700 710 720 730 740
790 800 810 820 830 840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
750 760 770 780 790 800
850 860 870 880 890 900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
810 820 830 840 850 860
910 920 930 940 950 960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
1110 1120 1130 1140 1150 1160
1210 1220
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
::::::::::::::::.::::::::::
XP_016 STKIYTPGRKEQGEPMTPRRTPARFGL
1170 1180 1190
>>NP_001309146 (OMIM: 600396) ATP-dependent RNA helicase (1129 aa)
initn: 2544 init1: 1248 opt: 2545 Z-score: 1526.6 bits: 294.4 E(85289): 2.7e-78
Smith-Waterman score: 2617; 41.4% identity (69.5% similar) in 1084 aa overlap (133-1177:70-1119)
110 120 130 140 150 160
pF1KSD NIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDR
.::. :.:.. ..:.... .....:::
NP_001 RTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDR----TKKKKRSRSRDRNRDR
40 50 60 70 80 90
170 180 190 200 210 220
pF1KSD DYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGY
: ::.:.::. . :: :::. . :. .::. .: :.: .. . . ...:. :
NP_001 DRDRERNRDRDHKRRHRSRSR---SRSRTRERNKVKS-RYRSRSRSQSPPKDRKDRDK-Y
100 110 120 130 140 150
230 240 250 260 270
pF1KSD GSSRRSQW-----ESPSPT-PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNE
: ..: . : : :. : .. : . : . . : .
NP_001 GERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQF-----GCFVQLEGLRKRWEGLVH
160 170 180 190 200
280 290 300 310 320 330
pF1KSD WADDRRHLGSTPRLSR--GRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGY
.. ::. : . .. ..:.: . . .:: . . .: ::. .. : .
NP_001 ISELRRE-GRVANVADVVSKGQRVKVKV-LSFTGTKTSLSMKDVDQETGE------DLNP
210 220 230 240 250
340 350 360 370 380
pF1KSD DEFHNPLAYSSEDYVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTS
.. .: .. ..:. : : :: . .. : .:..... : :.:: ..:...
NP_001 NRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAA
260 270 280 290 300 310
390 400 410 420 430
pF1KSD GVVHRLEV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK
.:. . : :: : :::. ...:. .. :::: :. . . :. ::
NP_001 NVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVK
320 330 340 350 360 370
440 450 460 470 480
pF1KSD DATSDLAIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEE
. ..:. : : ....:: :. ...:. .::: : : : .
NP_001 NPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAA
380 390 400 410 420 430
490 500 510 520 530 540
pF1KSD EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTII
. . . .. :. . .:: . ::::::. :::. ....:. .
NP_001 NMRGIGMMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAV
440 450 460 470 480
550 560 570 580 590 600
pF1KSD RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNL
.::.:.::.::::::::::.:::: : :::. : :::::::::::::::::::::.: :
NP_001 HDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCL
490 500 510 520 530 540
610 620 630 640 650 660
pF1KSD GEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLF
:.::::.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...:::::
NP_001 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF
550 560 570 580 590 600
670 680 690 700 710 720
pF1KSD GLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVE
:::...: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..
NP_001 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLD
610 620 630 640 650 660
730 740 750 760 770 780
pF1KSD AAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPS
:.. .:.::. :::::.:. :::.:... . . :... : ..: : .::.:: :::
NP_001 ASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS
670 680 690 700 710 720
790 800 810 820 830 840
pF1KSD DLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYP
..:..::. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :
NP_001 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP
730 740 750 760 770 780
850 860 870 880 890 900
pF1KSD ISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ
::::.:.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..
NP_001 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGIN
790 800 810 820 830 840
910 920 930 940 950 960
pF1KSD DLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCD
:::.: ::: :: ......: ::. :::::. : :: :: :.::::.: : ::::.:
NP_001 DLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVH
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KSD MGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYS
.::: :.: ::::::: .::::: .. .:: . :: :.:::: : :: .::::..:
NP_001 LGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFS
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KSD TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL
. :: ..::.:...:.....: :. :: .......::: . :.: ::...:..:::
NP_001 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKK
970 980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KSD KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAEL
: .. . ..::.:.::. :...::::::.::::::. ::..: .::.:.
NP_001 DPQEGYRTLIDQQVVYIHPSSALFN--RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KSD GPMFYSVKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTK
.: :..:.. : :.:....: . . .:: :
NP_001 APAFFKVSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR
1090 1100 1110 1120
1210 1220
pF1KSD IYTPGRKEQGEPMAPRRTPARFGL
>>NP_004932 (OMIM: 600396) ATP-dependent RNA helicase DH (1220 aa)
initn: 2544 init1: 1248 opt: 2545 Z-score: 1526.2 bits: 294.5 E(85289): 2.9e-78
Smith-Waterman score: 2617; 41.4% identity (69.5% similar) in 1084 aa overlap (133-1177:161-1210)
110 120 130 140 150 160
pF1KSD NIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDR
.::. :.:.. ..:.... .....:::
NP_004 RTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDR----TKKKKRSRSRDRNRDR
140 150 160 170 180
170 180 190 200 210 220
pF1KSD DYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGY
: ::.:.::. . :: :::. . :. .::. .: :.: .. . . ...:. :
NP_004 DRDRERNRDRDHKRRHRSRSR---SRSRTRERNKVKS-RYRSRSRSQSPPKDRKDRDK-Y
190 200 210 220 230 240
230 240 250 260 270
pF1KSD GSSRRSQW-----ESPSPT-PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNE
: ..: . : : :. : .. : . : . . : .
NP_004 GERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQF-----GCFVQLEGLRKRWEGLVH
250 260 270 280 290
280 290 300 310 320 330
pF1KSD WADDRRHLGSTPRLSR--GRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGY
.. ::. : . .. ..:.: . . .:: . . .: ::. .. : .
NP_004 ISELRRE-GRVANVADVVSKGQRVKVKV-LSFTGTKTSLSMKDVDQETGE------DLNP
300 310 320 330 340
340 350 360 370 380
pF1KSD DEFHNPLAYSSEDYVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTS
.. .: .. ..:. : : :: . .. : .:..... : :.:: ..:...
NP_004 NRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAA
350 360 370 380 390 400
390 400 410 420 430
pF1KSD GVVHRLEV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK
.:. . : :: : :::. ...:. .. :::: :. . . :. ::
NP_004 NVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVK
410 420 430 440 450 460
440 450 460 470 480
pF1KSD DATSDLAIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEE
. ..:. : : ....:: :. ...:. .::: : : : .
NP_004 NPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAA
470 480 490 500 510 520
490 500 510 520 530 540
pF1KSD EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTII
. . . .. :. . .:: . ::::::. :::. ....:. .
NP_004 NMRGIGMMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAV
530 540 550 560 570
550 560 570 580 590 600
pF1KSD RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNL
.::.:.::.::::::::::.:::: : :::. : :::::::::::::::::::::.: :
NP_004 HDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCL
580 590 600 610 620 630
610 620 630 640 650 660
pF1KSD GEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLF
:.::::.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...:::::
NP_004 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF
640 650 660 670 680 690
670 680 690 700 710 720
pF1KSD GLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVE
:::...: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..
NP_004 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLD
700 710 720 730 740 750
730 740 750 760 770 780
pF1KSD AAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPS
:.. .:.::. :::::.:. :::.:... . . :... : ..: : .::.:: :::
NP_004 ASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS
760 770 780 790 800 810
790 800 810 820 830 840
pF1KSD DLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYP
..:..::. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :
NP_004 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP
820 830 840 850 860 870
850 860 870 880 890 900
pF1KSD ISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ
::::.:.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..
NP_004 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGIN
880 890 900 910 920 930
910 920 930 940 950 960
pF1KSD DLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCD
:::.: ::: :: ......: ::. :::::. : :: :: :.::::.: : ::::.:
NP_004 DLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVH
940 950 960 970 980 990
970 980 990 1000 1010 1020
pF1KSD MGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYS
.::: :.: ::::::: .::::: .. .:: . :: :.:::: : :: .::::..:
NP_004 LGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFS
1000 1010 1020 1030 1040 1050
1030 1040 1050 1060 1070 1080
pF1KSD TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL
. :: ..::.:...:.....: :. :: .......::: . :.: ::...:..:::
NP_004 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKK
1060 1070 1080 1090 1100 1110
1090 1100 1110 1120 1130 1140
pF1KSD KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAEL
: .. . ..::.:.::. :...::::::.::::::. ::..: .::.:.
NP_004 DPQEGYRTLIDQQVVYIHPSSALFN--RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF
1120 1130 1140 1150 1160 1170
1150 1160 1170 1180 1190 1200
pF1KSD GPMFYSVKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTK
.: :..:.. : :.:....: . . .:: :
NP_004 APAFFKVSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR
1180 1190 1200 1210 1220
1210 1220
pF1KSD IYTPGRKEQGEPMAPRRTPARFGL
>>NP_001309150 (OMIM: 600396) ATP-dependent RNA helicase (1218 aa)
initn: 2609 init1: 1248 opt: 2537 Z-score: 1521.4 bits: 293.6 E(85289): 5.3e-78
Smith-Waterman score: 2611; 41.4% identity (69.3% similar) in 1084 aa overlap (133-1177:161-1208)
110 120 130 140 150 160
pF1KSD NIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDR
.::. :.: ..:.... .....:::
NP_001 RTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHR------TKKKKRSRSRDRNRDR
140 150 160 170 180
170 180 190 200 210 220
pF1KSD DYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGY
: ::.:.::. . :: :::. . :. .::. .: :.: .. . . ...:. :
NP_001 DRDRERNRDRDHKRRHRSRSR---SRSRTRERNKVKS-RYRSRSRSQSPPKDRKDRDK-Y
190 200 210 220 230
230 240 250 260 270
pF1KSD GSSRRSQW-----ESPSPT-PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNE
: ..: . : : :. : .. : . : . . : .
NP_001 GERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQF-----GCFVQLEGLRKRWEGLVH
240 250 260 270 280 290
280 290 300 310 320 330
pF1KSD WADDRRHLGSTPRLSR--GRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGY
.. ::. : . .. ..:.: . . .:: . . .: ::. .. : .
NP_001 ISELRRE-GRVANVADVVSKGQRVKVKV-LSFTGTKTSLSMKDVDQETGE------DLNP
300 310 320 330 340
340 350 360 370 380
pF1KSD DEFHNPLAYSSEDYVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTS
.. .: .. ..:. : : :: . .. : .:..... : :.:: ..:...
NP_001 NRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAA
350 360 370 380 390 400
390 400 410 420 430
pF1KSD GVVHRLEV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK
.:. . : :: : :::. ...:. .. :::: :. . . :. ::
NP_001 NVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVK
410 420 430 440 450 460
440 450 460 470 480
pF1KSD DATSDLAIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEE
. ..:. : : ....:: :. ...:. .::: : : : .
NP_001 NPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAA
470 480 490 500 510 520
490 500 510 520 530 540
pF1KSD EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTII
. . . .. :. . .:: . ::::::. :::. ....:. .
NP_001 NMRGIGMMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAV
530 540 550 560 570
550 560 570 580 590 600
pF1KSD RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNL
.::.:.::.::::::::::.:::: : :::. : :::::::::::::::::::::.: :
NP_001 HDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCL
580 590 600 610 620 630
610 620 630 640 650 660
pF1KSD GEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLF
:.::::.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...:::::
NP_001 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF
640 650 660 670 680 690
670 680 690 700 710 720
pF1KSD GLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVE
:::...: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..
NP_001 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLD
700 710 720 730 740 750
730 740 750 760 770 780
pF1KSD AAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPS
:.. .:.::. :::::.:. :::.:... . . :... : ..: : .::.:: :::
NP_001 ASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS
760 770 780 790 800 810
790 800 810 820 830 840
pF1KSD DLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYP
..:..::. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :
NP_001 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP
820 830 840 850 860 870
850 860 870 880 890 900
pF1KSD ISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ
::::.:.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..
NP_001 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGIN
880 890 900 910 920 930
910 920 930 940 950 960
pF1KSD DLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCD
:::.: ::: :: ......: ::. :::::. : :: :: :.::::.: : ::::.:
NP_001 DLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVH
940 950 960 970 980 990
970 980 990 1000 1010 1020
pF1KSD MGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYS
.::: :.: ::::::: .::::: .. .:: . :: :.:::: : :: .::::..:
NP_001 LGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFS
1000 1010 1020 1030 1040 1050
1030 1040 1050 1060 1070 1080
pF1KSD TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL
. :: ..::.:...:.....: :. :: .......::: . :.: ::...:..:::
NP_001 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKK
1060 1070 1080 1090 1100 1110
1090 1100 1110 1120 1130 1140
pF1KSD KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAEL
: .. . ..::.:.::. :...::::::.::::::. ::..: .::.:.
NP_001 DPQEGYRTLIDQQVVYIHPSSALFN--RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF
1120 1130 1140 1150 1160 1170
1150 1160 1170 1180 1190 1200
pF1KSD GPMFYSVKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTK
.: :..:.. : :.:....: . . .:: :
NP_001 APAFFKVSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR
1180 1190 1200 1210
1210 1220
pF1KSD IYTPGRKEQGEPMAPRRTPARFGL
>>NP_001309145 (OMIM: 600396) ATP-dependent RNA helicase (945 aa)
initn: 2483 init1: 1248 opt: 2481 Z-score: 1489.5 bits: 287.3 E(85289): 3.1e-76
Smith-Waterman score: 2513; 47.3% identity (74.6% similar) in 838 aa overlap (364-1177:110-935)
340 350 360 370 380 390
pF1KSD DEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINE--DNERWETNRMLTSGVVHRL
: .:..... : :.:: ..:....:. .
NP_001 VGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKE
80 90 100 110 120 130
400 410 420 430 440
pF1KSD EV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDL
: :: : :::. ...:. .. :::: :. . . :. ::. ..:
NP_001 EFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVKNPDGSL
140 150 160 170 180 190
450 460 470 480 490
pF1KSD AIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEEEPDKAV
. : : ....:: :. ...:. .::: : : : . .
NP_001 SQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAANMRGIG
200 210 220 230 240 250
500 510 520 530 540 550
pF1KSD TEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIV
. . .. :. . .:: . ::::::. :::. ....:. ..::.:.
NP_001 MMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQIL
260 270 280 290 300
560 570 580 590 600 610
pF1KSD IVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGY
::.::::::::::.:::: : :::. : :::::::::::::::::::::.: ::.::::
NP_001 IVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGY
310 320 330 340 350 360
620 630 640 650 660 670
pF1KSD AIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREV
.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...::::::::...
NP_001 TIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKT
370 380 390 400 410 420
680 690 700 710 720 730
pF1KSD VARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQS
: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..:..
NP_001 VQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITV
430 440 450 460 470 480
740 750 760 770 780 790
pF1KSD LQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPSDLQAKI
.:.::. :::::.:. :::.:... . . :... : ..: : .::.:: :::..:..:
NP_001 MQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRI
490 500 510 520 530 540
800 810 820 830 840 850
pF1KSD FQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANA
:. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :::::.:
NP_001 FDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQA
550 560 570 580 590 600
860 870 880 890 900 910
pF1KSD NQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFH
.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..:::.:
NP_001 KQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFD
610 620 630 640 650 660
920 930 940 950 960 970
pF1KSD FMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSE
::: :: ......: ::. :::::. : :: :: :.::::.: : ::::.: .::: :
NP_001 FMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEE
670 680 690 700 710 720
980 990 1000 1010 1020 1030
pF1KSD ILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCND
.: ::::::: .::::: .. .:: . :: :.:::: : :: .::::..:. :: .
NP_001 MLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYE
730 740 750 760 770 780
1040 1050 1060 1070 1080 1090
pF1KSD HFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEY
.::.:...:.....: :. :: .......::: . :.: ::...:..::: :
NP_001 NFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGY
790 800 810 820 830 840
1100 1110 1120 1130 1140 1150
pF1KSD VNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYS
.. . ..::.:.::. :...::::::.::::::. ::..: .::.:..: :..
NP_001 RTLIDQQVVYIHPSSALFN--RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFK
850 860 870 880 890 900
1160 1170 1180 1190 1200
pF1KSD VKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTKIYTPGR
:.. : :.:....: . . .:: :
NP_001 VSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR
910 920 930 940
>>NP_001309148 (OMIM: 600396) ATP-dependent RNA helicase (1169 aa)
initn: 2437 init1: 1248 opt: 2374 Z-score: 1425.0 bits: 275.7 E(85289): 1.2e-72
Smith-Waterman score: 2446; 41.2% identity (68.9% similar) in 1025 aa overlap (133-1119:161-1151)
110 120 130 140 150 160
pF1KSD NIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDR
.::. :.:.. ..:.... .....:::
NP_001 RTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDR----TKKKKRSRSRDRNRDR
140 150 160 170 180
170 180 190 200 210 220
pF1KSD DYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGY
: ::.:.::. . :: :::. . :. .::. .: :.: .. . . ...:. :
NP_001 DRDRERNRDRDHKRRHRSRSR---SRSRTRERNKVKS-RYRSRSRSQSPPKDRKDRDK-Y
190 200 210 220 230 240
230 240 250 260 270
pF1KSD GSSRRSQW-----ESPSPT-PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNE
: ..: . : : :. : .. : . : . . : .
NP_001 GERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQF-----GCFVQLEGLRKRWEGLVH
250 260 270 280 290
280 290 300 310 320 330
pF1KSD WADDRRHLGSTPRLSR--GRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGY
.. ::. : . .. ..:.: . . .:: . . .: ::. .. : .
NP_001 ISELRRE-GRVANVADVVSKGQRVK-VKVLSFTGTKTSLSMKDVDQETGE------DLNP
300 310 320 330 340
340 350 360 370 380
pF1KSD DEFHNPLAYSSEDYVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTS
.. .: .. ..:. : : :: . .. : .:..... : :.:: ..:...
NP_001 NRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAA
350 360 370 380 390 400
390 400 410 420 430
pF1KSD GVVHRLEV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK
.:. . : :: : :::. ...:. .. :::: :. . . :. ::
NP_001 NVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVK
410 420 430 440 450 460
440 450 460 470 480
pF1KSD DATSDLAIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEE
. ..:. : : ....:: :. ...:. .::: : : : .
NP_001 NPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAA
470 480 490 500 510 520
490 500 510 520 530 540
pF1KSD EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTII
. . . .. :. . .:: . ::::::. :::. ....:. .
NP_001 NMRGIGMMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAV
530 540 550 560 570
550 560 570 580 590 600
pF1KSD RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNL
.::.:.::.::::::::::.:::: : :::. : :::::::::::::::::::::.: :
NP_001 HDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCL
580 590 600 610 620 630
610 620 630 640 650 660
pF1KSD GEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLF
:.::::.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...:::::
NP_001 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF
640 650 660 670 680 690
670 680 690 700 710 720
pF1KSD GLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVE
:::...: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..
NP_001 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLD
700 710 720 730 740 750
730 740 750 760 770 780
pF1KSD AAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPS
:.. .:.::. :::::.:. :::.:... . . :... : ..: : .::.:: :::
NP_001 ASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS
760 770 780 790 800 810
790 800 810 820 830 840
pF1KSD DLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYP
..:..::. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :
NP_001 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP
820 830 840 850 860 870
850 860 870 880 890 900
pF1KSD ISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ
::::.:.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..
NP_001 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGIN
880 890 900 910 920 930
910 920 930 940 950 960
pF1KSD DLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCD
:::.: ::: :: ......: ::. :::::. : :: :: :.::::.: : ::::.:
NP_001 DLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVH
940 950 960 970 980 990
970 980 990 1000 1010 1020
pF1KSD MGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYS
.::: :.: ::::::: .::::: .. .:: . :: :.:::: : :: .::::..:
NP_001 LGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFS
1000 1010 1020 1030 1040 1050
1030 1040 1050 1060 1070 1080
pF1KSD TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL
. :: ..::.:...:.....: :. :: .......::: . :.: ::...:..:::
NP_001 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKK
1060 1070 1080 1090 1100 1110
1090 1100 1110 1120 1130 1140
pF1KSD KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAEL
: .. . ..::.:.::. :.. .:
NP_001 DPQEGYRTLIDQQVVYIHPSSALFN--RQPEWDLYSRFSEWKSGTNCSSLSGT
1120 1130 1140 1150 1160
1150 1160 1170 1180 1190 1200
pF1KSD GPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTKI
1227 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:48:28 2016 done: Thu Nov 3 00:48:30 2016
Total Scan time: 14.540 Total Display time: 0.480
Function used was FASTA [36.3.4 Apr, 2011]