Result of FASTA (omim) for
pFN21ASDA0076
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0076, 1698 aa
1>>>pF1KSDA0076 1698 - 1698 aa - 1698 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6287+/-0.000368; mu= 23.5076+/- 0.023
mean_var=85.1918+/-16.810, 0's: 0 Z-trim(115.2): 73 B-trim: 58 in 1/53
Lambda= 0.138955
statistics sampled from 25419 (25492) to 25419 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.299), width: 16
Scan time: 18.610
The best scores are: opt bits E(85289)
NP_055595 (OMIM: 273750,609577) cullin-7 isoform 2 (1698) 11425 2301.3 0
XP_005249560 (OMIM: 273750,609577) PREDICTED: cull (1750) 11425 2301.3 0
XP_016867028 (OMIM: 273750,609577) PREDICTED: cull (1702) 11407 2297.7 0
XP_011513322 (OMIM: 273750,609577) PREDICTED: cull (1754) 11407 2297.7 0
XP_016867026 (OMIM: 273750,609577) PREDICTED: cull (1730) 10099 2035.5 0
NP_001161842 (OMIM: 273750,609577) cullin-7 isofor (1782) 10099 2035.5 0
XP_006715348 (OMIM: 273750,609577) PREDICTED: cull (1734) 10081 2031.9 0
XP_011513321 (OMIM: 273750,609577) PREDICTED: cull (1786) 10081 2031.9 0
XP_016867023 (OMIM: 273750,609577) PREDICTED: cull (1791) 7889 1592.5 0
XP_016867027 (OMIM: 273750,609577) PREDICTED: cull (1711) 7871 1588.8 0
XP_016867025 (OMIM: 273750,609577) PREDICTED: cull (1743) 7871 1588.8 0
XP_016867024 (OMIM: 273750,609577) PREDICTED: cull (1763) 7871 1588.8 0
XP_016867022 (OMIM: 273750,609577) PREDICTED: cull (1795) 7871 1588.8 0
XP_011513323 (OMIM: 273750,609577) PREDICTED: cull ( 989) 6567 1327.2 0
NP_055904 (OMIM: 607489) cullin-9 [Homo sapiens] (2517) 3425 697.7 3.5e-199
XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 is (1834) 2833 578.9 1.5e-163
XP_011512730 (OMIM: 607489) PREDICTED: cullin-9 is (1851) 2833 578.9 1.5e-163
XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 is (1909) 2833 578.9 1.5e-163
XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 is (2095) 2833 578.9 1.6e-163
XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 is (2339) 2833 579.0 1.8e-163
XP_011512727 (OMIM: 607489) PREDICTED: cullin-9 is (2456) 2833 579.0 1.8e-163
XP_011512725 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 2833 579.0 1.9e-163
XP_011512724 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 2833 579.0 1.9e-163
XP_016866078 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 2833 579.0 1.9e-163
XP_011512726 (OMIM: 607489) PREDICTED: cullin-9 is (2539) 2807 573.8 6.9e-162
XP_011512732 (OMIM: 607489) PREDICTED: cullin-9 is (1403) 2247 461.3 2.7e-128
XP_016867029 (OMIM: 273750,609577) PREDICTED: cull ( 897) 2220 455.8 8.2e-127
XP_016878186 (OMIM: 176270,227220,605837,615516) P (2556) 324 76.0 4.9e-12
XP_016878187 (OMIM: 176270,227220,605837,615516) P (2556) 324 76.0 4.9e-12
XP_011520435 (OMIM: 176270,227220,605837,615516) P (3749) 324 76.1 6.6e-12
XP_011520433 (OMIM: 176270,227220,605837,615516) P (4673) 324 76.2 7.8e-12
XP_006720790 (OMIM: 176270,227220,605837,615516) P (4748) 324 76.2 7.9e-12
XP_005268333 (OMIM: 176270,227220,605837,615516) P (4796) 324 76.2 8e-12
XP_016878185 (OMIM: 176270,227220,605837,615516) P (4796) 324 76.2 8e-12
XP_016878184 (OMIM: 176270,227220,605837,615516) P (4796) 324 76.2 8e-12
XP_006720789 (OMIM: 176270,227220,605837,615516) P (4829) 324 76.2 8e-12
NP_004658 (OMIM: 176270,227220,605837,615516) E3 u (4834) 324 76.2 8e-12
XP_016868212 (OMIM: 603134) PREDICTED: cullin-1 is ( 455) 186 47.8 0.00027
XP_005250117 (OMIM: 603134) PREDICTED: cullin-1 is ( 776) 186 48.0 0.00041
NP_003583 (OMIM: 603134) cullin-1 [Homo sapiens] ( 776) 186 48.0 0.00041
XP_011514934 (OMIM: 603134) PREDICTED: cullin-1 is ( 776) 186 48.0 0.00041
XP_011514931 (OMIM: 603134) PREDICTED: cullin-1 is ( 776) 186 48.0 0.00041
XP_011514933 (OMIM: 603134) PREDICTED: cullin-1 is ( 776) 186 48.0 0.00041
XP_011514932 (OMIM: 603134) PREDICTED: cullin-1 is ( 776) 186 48.0 0.00041
NP_055700 (OMIM: 613745) anaphase-promoting comple ( 185) 168 43.9 0.0016
NP_001243636 (OMIM: 613745) anaphase-promoting com ( 185) 168 43.9 0.0016
NP_001243637 (OMIM: 613745) anaphase-promoting com ( 185) 168 43.9 0.0016
NP_001243635 (OMIM: 613745) anaphase-promoting com ( 185) 168 43.9 0.0016
XP_011529826 (OMIM: 613745) PREDICTED: anaphase-pr ( 185) 168 43.9 0.0016
NP_001243638 (OMIM: 613745) anaphase-promoting com ( 196) 168 43.9 0.0017
>>NP_055595 (OMIM: 273750,609577) cullin-7 isoform 2 [Ho (1698 aa)
initn: 11425 init1: 11425 opt: 11425 Z-score: 12366.8 bits: 2301.3 E(85289): 0
Smith-Waterman score: 11425; 99.9% identity (100.0% similar) in 1698 aa overlap (1-1698:1-1698)
10 20 30 40 50 60
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD GTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD YWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPED
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIELA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD QDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQAKD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQLQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD RQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSPNT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD DREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFKCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFKCE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD KHAHLYRKLITNILGGCIQMVLGQIEDHRRTHRPINIPFFDVFLRYLCQGSSVEVKEDKC
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_055 KHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRYLCQGSSVEVKEDKC
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD WEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDSSY
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD MPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGIDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGIDTR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD EQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEAVF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD NPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSSIM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD RNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQNG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD CAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGLEI
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD ATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQFHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQFHV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD YQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENEDL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD YYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPALER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPALER
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD GSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADMLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADMLNQ
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD AIGPLTSSRGPLDLHEQKDIPGGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AIGPLTSSRGPLDLHEQKDIPGGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD EKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTD
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD VLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQIRS
1630 1640 1650 1660 1670 1680
1690
pF1KSD RGVPYASCTATQSFSTFR
::::::::::::::::::
NP_055 RGVPYASCTATQSFSTFR
1690
>>XP_005249560 (OMIM: 273750,609577) PREDICTED: cullin-7 (1750 aa)
initn: 11425 init1: 11425 opt: 11425 Z-score: 12366.6 bits: 2301.3 E(85289): 0
Smith-Waterman score: 11425; 99.9% identity (100.0% similar) in 1698 aa overlap (1-1698:53-1750)
10 20 30
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRV
::::::::::::::::::::::::::::::
XP_005 ADSRGCSSVPRRHAPSRLSVSTPSRGPGARMVGELRYREFRVPLGPGLHAYPDELIRQRV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KSD GHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KSD PSQESAGEVGALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSQESAGEVGALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASI
150 160 170 180 190 200
160 170 180 190 200 210
pF1KSD EPLTGVFKDPRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAGTRTQILLSLSQQEAIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPLTGVFKDPRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAGTRTQILLSLSQQEAIE
210 220 230 240 250 260
220 230 240 250 260 270
pF1KSD KHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDS
270 280 290 300 310 320
280 290 300 310 320 330
pF1KSD AAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISELVQAMRWDQASDRPRSSARSPGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISELVQAMRWDQASDRPRSSARSPGSI
330 340 350 360 370 380
340 350 360 370 380 390
pF1KSD FQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDDYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDDYE
390 400 410 420 430 440
400 410 420 430 440 450
pF1KSD EISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQGAV
450 460 470 480 490 500
460 470 480 490 500 510
pF1KSD ASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPDHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPDHQ
510 520 530 540 550 560
520 530 540 550 560 570
pF1KSD EVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYGP
570 580 590 600 610 620
580 590 600 610 620 630
pF1KSD EALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGP
630 640 650 660 670 680
640 650 660 670 680 690
pF1KSD AGKILLDLEQALSSEGTQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGKILLDLEQALSSEGTQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLRIL
690 700 710 720 730 740
700 710 720 730 740 750
pF1KSD KQLVDFPEALLLPWHEAVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQLVDFPEALLLPWHEAVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQLG
750 760 770 780 790 800
760 770 780 790 800 810
pF1KSD ARDAISKALEKHLGKLELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARDAISKALEKHLGKLELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDHRR
810 820 830 840 850 860
820 830 840 850 860 870
pF1KSD THRPINIPFFDVFLRYLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGS
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THQPINIPFFDVFLRYLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGS
870 880 890 900 910 920
880 890 900 910 920 930
pF1KSD AGSHYITLHMRRGILIRQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGSHYITLHMRRGILIRQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPSAS
930 940 950 960 970 980
940 950 960 970 980 990
pF1KSD RVILLENLTRFWPIIQIRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLFYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVILLENLTRFWPIIQIRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLFYM
990 1000 1010 1020 1030 1040
1000 1010 1020 1030 1040 1050
pF1KSD VRAQAWSQDMAEDRRSLLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRAQAWSQDMAEDRRSLLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVSPV
1050 1060 1070 1080 1090 1100
1060 1070 1080 1090 1100 1110
pF1KSD VQNITSPDEDGISPLGWLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQNITSPDEDGISPLGWLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPP
1110 1120 1130 1140 1150 1160
1120 1130 1140 1150 1160 1170
pF1KSD PVVATPRPKGRNRSHDWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVVATPRPKGRNRSHDWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVP
1170 1180 1190 1200 1210 1220
1180 1190 1200 1210 1220 1230
pF1KSD RYCEHFNILQNSSSELFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYCEHFNILQNSSSELFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQG
1230 1240 1250 1260 1270 1280
1240 1250 1260 1270 1280 1290
pF1KSD SRIGGAQEMERLAQLQQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRIGGAQEMERLAQLQQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAVLE
1290 1300 1310 1320 1330 1340
1300 1310 1320 1330 1340 1350
pF1KSD QIGPCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QIGPCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKE
1350 1360 1370 1380 1390 1400
1360 1370 1380 1390 1400 1410
pF1KSD HKSEKEEEAGAAAVVDVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKSEKEEEAGAAAVVDVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTLNP
1410 1420 1430 1440 1450 1460
1420 1430 1440 1450 1460 1470
pF1KSD RTCLPSYLRGTLNRYSNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTCLPSYLRGTLNRYSNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTVQM
1470 1480 1490 1500 1510 1520
1480 1490 1500 1510 1520 1530
pF1KSD WLLLYLNDLKAVSVESLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIPGGVLKIRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLLLYLNDLKAVSVESLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIPGGVLKIRDG
1530 1540 1550 1560 1570 1580
1540 1550 1560 1570 1580 1590
pF1KSD SKEPRSRWDIVRLIPPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKEPRSRWDIVRLIPPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVC
1590 1600 1610 1620 1630 1640
1600 1610 1620 1630 1640 1650
pF1KSD LVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVPV
1650 1660 1670 1680 1690 1700
1660 1670 1680 1690
pF1KSD TVMEPHTESLNPGSSGPNPPLTFHTLQIRSRGVPYASCTATQSFSTFR
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVMEPHTESLNPGSSGPNPPLTFHTLQIRSRGVPYASCTATQSFSTFR
1710 1720 1730 1740 1750
>>XP_016867028 (OMIM: 273750,609577) PREDICTED: cullin-7 (1702 aa)
initn: 11452 init1: 10220 opt: 11407 Z-score: 12347.3 bits: 2297.7 E(85289): 0
Smith-Waterman score: 11407; 99.7% identity (99.8% similar) in 1702 aa overlap (1-1698:1-1702)
10 20 30 40 50 60
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD GTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD YWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPED
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIELA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD QDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQAKD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQLQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD RQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSPNT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD DREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFKCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFKCE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD KHAHLYRKLITNILGGCIQMVLGQIEDHRRTHRPINIPFFDVFLRYLCQGSSVEVKEDKC
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 KHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRYLCQGSSVEVKEDKC
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD WEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDSSY
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD MPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGIDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGIDTR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD EQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEAVF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD NPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSSIM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD RNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQNG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD CAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGLEI
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD ATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQFHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQFHV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD YQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENEDL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD YYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPALER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPALER
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD GSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADMLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADMLNQ
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550
pF1KSD AIGPLTSSRGPLDLHEQKDIPG----GVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGED
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_016 AIGPLTSSRGPLDLHEQKDIPGAFISGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGED
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KSD GQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSAC
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KSD SSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTL
1630 1640 1650 1660 1670 1680
1680 1690
pF1KSD QIRSRGVPYASCTATQSFSTFR
::::::::::::::::::::::
XP_016 QIRSRGVPYASCTATQSFSTFR
1690 1700
>>XP_011513322 (OMIM: 273750,609577) PREDICTED: cullin-7 (1754 aa)
initn: 11452 init1: 10220 opt: 11407 Z-score: 12347.1 bits: 2297.7 E(85289): 0
Smith-Waterman score: 11407; 99.7% identity (99.8% similar) in 1702 aa overlap (1-1698:53-1754)
10 20 30
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRV
::::::::::::::::::::::::::::::
XP_011 ADSRGCSSVPRRHAPSRLSVSTPSRGPGARMVGELRYREFRVPLGPGLHAYPDELIRQRV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KSD GHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KSD PSQESAGEVGALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSQESAGEVGALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASI
150 160 170 180 190 200
160 170 180 190 200 210
pF1KSD EPLTGVFKDPRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAGTRTQILLSLSQQEAIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPLTGVFKDPRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAGTRTQILLSLSQQEAIE
210 220 230 240 250 260
220 230 240 250 260 270
pF1KSD KHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDS
270 280 290 300 310 320
280 290 300 310 320 330
pF1KSD AAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISELVQAMRWDQASDRPRSSARSPGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISELVQAMRWDQASDRPRSSARSPGSI
330 340 350 360 370 380
340 350 360 370 380 390
pF1KSD FQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDDYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDDYE
390 400 410 420 430 440
400 410 420 430 440 450
pF1KSD EISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQGAV
450 460 470 480 490 500
460 470 480 490 500 510
pF1KSD ASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPDHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPDHQ
510 520 530 540 550 560
520 530 540 550 560 570
pF1KSD EVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYGP
570 580 590 600 610 620
580 590 600 610 620 630
pF1KSD EALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGP
630 640 650 660 670 680
640 650 660 670 680 690
pF1KSD AGKILLDLEQALSSEGTQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKILLDLEQALSSEGTQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLRIL
690 700 710 720 730 740
700 710 720 730 740 750
pF1KSD KQLVDFPEALLLPWHEAVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLVDFPEALLLPWHEAVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQLG
750 760 770 780 790 800
760 770 780 790 800 810
pF1KSD ARDAISKALEKHLGKLELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARDAISKALEKHLGKLELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDHRR
810 820 830 840 850 860
820 830 840 850 860 870
pF1KSD THRPINIPFFDVFLRYLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGS
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THQPINIPFFDVFLRYLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGS
870 880 890 900 910 920
880 890 900 910 920 930
pF1KSD AGSHYITLHMRRGILIRQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGSHYITLHMRRGILIRQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPSAS
930 940 950 960 970 980
940 950 960 970 980 990
pF1KSD RVILLENLTRFWPIIQIRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLFYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVILLENLTRFWPIIQIRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLFYM
990 1000 1010 1020 1030 1040
1000 1010 1020 1030 1040 1050
pF1KSD VRAQAWSQDMAEDRRSLLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRAQAWSQDMAEDRRSLLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVSPV
1050 1060 1070 1080 1090 1100
1060 1070 1080 1090 1100 1110
pF1KSD VQNITSPDEDGISPLGWLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQNITSPDEDGISPLGWLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPP
1110 1120 1130 1140 1150 1160
1120 1130 1140 1150 1160 1170
pF1KSD PVVATPRPKGRNRSHDWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVVATPRPKGRNRSHDWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVP
1170 1180 1190 1200 1210 1220
1180 1190 1200 1210 1220 1230
pF1KSD RYCEHFNILQNSSSELFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYCEHFNILQNSSSELFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQG
1230 1240 1250 1260 1270 1280
1240 1250 1260 1270 1280 1290
pF1KSD SRIGGAQEMERLAQLQQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRIGGAQEMERLAQLQQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAVLE
1290 1300 1310 1320 1330 1340
1300 1310 1320 1330 1340 1350
pF1KSD QIGPCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIGPCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKE
1350 1360 1370 1380 1390 1400
1360 1370 1380 1390 1400 1410
pF1KSD HKSEKEEEAGAAAVVDVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKSEKEEEAGAAAVVDVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTLNP
1410 1420 1430 1440 1450 1460
1420 1430 1440 1450 1460 1470
pF1KSD RTCLPSYLRGTLNRYSNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTCLPSYLRGTLNRYSNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTVQM
1470 1480 1490 1500 1510 1520
1480 1490 1500 1510 1520
pF1KSD WLLLYLNDLKAVSVESLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIPG----GVLK
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 WLLLYLNDLKAVSVESLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIPGAFISGVLK
1530 1540 1550 1560 1570 1580
1530 1540 1550 1560 1570 1580
pF1KSD IRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHID
1590 1600 1610 1620 1630 1640
1590 1600 1610 1620 1630 1640
pF1KSD QLVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSY
1650 1660 1670 1680 1690 1700
1650 1660 1670 1680 1690
pF1KSD AVPVTVMEPHTESLNPGSSGPNPPLTFHTLQIRSRGVPYASCTATQSFSTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVPVTVMEPHTESLNPGSSGPNPPLTFHTLQIRSRGVPYASCTATQSFSTFR
1710 1720 1730 1740 1750
>>XP_016867026 (OMIM: 273750,609577) PREDICTED: cullin-7 (1730 aa)
initn: 11411 init1: 10099 opt: 10099 Z-score: 10930.0 bits: 2035.5 E(85289): 0
Smith-Waterman score: 11351; 98.1% identity (98.2% similar) in 1730 aa overlap (1-1698:1-1730)
10 20 30 40 50 60
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
130 140 150 160 170 180
190 200
pF1KSD AGRMIQALSSHDAG--------------------------------TRTQILLSLSQQEA
:::::::::::::: ::::::::::::::
XP_016 AGRMIQALSSHDAGEGQCGEEGKAGEGLGRLRDSQDTVAGASDLIRTRTQILLSLSQQEA
190 200 210 220 230 240
210 220 230 240 250 260
pF1KSD IEKHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEKHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLN
250 260 270 280 290 300
270 280 290 300 310 320
pF1KSD DSAAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISELVQAMRWDQASDRPRSSARSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSAAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISELVQAMRWDQASDRPRSSARSPG
310 320 330 340 350 360
330 340 350 360 370 380
pF1KSD SIFQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIFQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDD
370 380 390 400 410 420
390 400 410 420 430 440
pF1KSD YEEISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEEISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQG
430 440 450 460 470 480
450 460 470 480 490 500
pF1KSD AVASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPD
490 500 510 520 530 540
510 520 530 540 550 560
pF1KSD HQEVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQEVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKY
550 560 570 580 590 600
570 580 590 600 610 620
pF1KSD GPEALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPEALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGY
610 620 630 640 650 660
630 640 650 660 670 680
pF1KSD GPAGKILLDLEQALSSEGTQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPAGKILLDLEQALSSEGTQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLR
670 680 690 700 710 720
690 700 710 720 730 740
pF1KSD ILKQLVDFPEALLLPWHEAVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILKQLVDFPEALLLPWHEAVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQ
730 740 750 760 770 780
750 760 770 780 790 800
pF1KSD LGARDAISKALEKHLGKLELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGARDAISKALEKHLGKLELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDH
790 800 810 820 830 840
810 820 830 840 850 860
pF1KSD RRTHRPINIPFFDVFLRYLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESN
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRTHQPINIPFFDVFLRYLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESN
850 860 870 880 890 900
870 880 890 900 910 920
pF1KSD GSAGSHYITLHMRRGILIRQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSAGSHYITLHMRRGILIRQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPS
910 920 930 940 950 960
930 940 950 960 970 980
pF1KSD ASRVILLENLTRFWPIIQIRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASRVILLENLTRFWPIIQIRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLF
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KSD YMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVS
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KSD PVVQNITSPDEDGISPLGWLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVVQNITSPDEDGISPLGWLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEA
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KSD PPPVVATPRPKGRNRSHDWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPVVATPRPKGRNRSHDWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDF
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KSD VPRYCEHFNILQNSSSELFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPRYCEHFNILQNSSSELFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQI
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KSD QGSRIGGAQEMERLAQLQQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGSRIGGAQEMERLAQLQQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAV
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KSD LEQIGPCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQIGPCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASG
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KSD KEHKSEKEEEAGAAAVVDVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEHKSEKEEEAGAAAVVDVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTL
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KSD NPRTCLPSYLRGTLNRYSNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPRTCLPSYLRGTLNRYSNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTV
1450 1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KSD QMWLLLYLNDLKAVSVESLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIPGGVLKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMWLLLYLNDLKAVSVESLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIPGGVLKIR
1510 1520 1530 1540 1550 1560
1530 1540 1550 1560 1570 1580
pF1KSD DGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQL
1570 1580 1590 1600 1610 1620
1590 1600 1610 1620 1630 1640
pF1KSD VCLVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCLVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAV
1630 1640 1650 1660 1670 1680
1650 1660 1670 1680 1690
pF1KSD PVTVMEPHTESLNPGSSGPNPPLTFHTLQIRSRGVPYASCTATQSFSTFR
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTVMEPHTESLNPGSSGPNPPLTFHTLQIRSRGVPYASCTATQSFSTFR
1690 1700 1710 1720 1730
>>NP_001161842 (OMIM: 273750,609577) cullin-7 isoform 1 (1782 aa)
initn: 11411 init1: 10099 opt: 10099 Z-score: 10929.9 bits: 2035.5 E(85289): 0
Smith-Waterman score: 11351; 98.1% identity (98.2% similar) in 1730 aa overlap (1-1698:53-1782)
10 20 30
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRV
::::::::::::::::::::::::::::::
NP_001 ADSRGCSSVPRRHAPSRLSVSTPSRGPGARMVGELRYREFRVPLGPGLHAYPDELIRQRV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KSD GHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KSD PSQESAGEVGALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSQESAGEVGALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASI
150 160 170 180 190 200
160 170 180 190
pF1KSD EPLTGVFKDPRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAG----------------
::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPLTGVFKDPRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAGEGQCGEEGKAGEGLGR
210 220 230 240 250 260
200 210 220 230
pF1KSD ----------------TRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFE
::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRDSQDTVAGASDLIRTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFE
270 280 290 300 310 320
240 250 260 270 280 290
pF1KSD GIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSM
330 340 350 360 370 380
300 310 320 330 340 350
pF1KSD AMGTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMGTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFR
390 400 410 420 430 440
360 370 380 390 400 410
pF1KSD PRSEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTG
450 460 470 480 490 500
420 430 440 450 460 470
pF1KSD RTYWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTYWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLP
510 520 530 540 550 560
480 490 500 510 520 530
pF1KSD EDEDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDEDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIE
570 580 590 600 610 620
540 550 560 570 580 590
pF1KSD LAQDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAQDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQA
630 640 650 660 670 680
600 610 620 630 640 650
pF1KSD KDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQ
690 700 710 720 730 740
660 670 680 690 700 710
pF1KSD LQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSP
750 760 770 780 790 800
720 730 740 750 760 770
pF1KSD NTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFK
810 820 830 840 850 860
780 790 800 810 820 830
pF1KSD CEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHRPINIPFFDVFLRYLCQGSSVEVKED
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_001 CEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRYLCQGSSVEVKED
870 880 890 900 910 920
840 850 860 870 880 890
pF1KSD KCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDS
930 940 950 960 970 980
900 910 920 930 940 950
pF1KSD SYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGID
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KSD TRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGAL
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KSD RQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEA
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KSD VFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSS
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KSD IMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQ
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KSD NGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGL
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KSD EIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQF
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KSD HVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENE
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KSD DLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPAL
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KSD ERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADML
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KSD NQAIGPLTSSRGPLDLHEQKDIPGGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQAIGPLTSSRGPLDLHEQKDIPGGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQ
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KSD NLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSS
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KSD TDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQI
1710 1720 1730 1740 1750 1760
1680 1690
pF1KSD RSRGVPYASCTATQSFSTFR
::::::::::::::::::::
NP_001 RSRGVPYASCTATQSFSTFR
1770 1780
>>XP_006715348 (OMIM: 273750,609577) PREDICTED: cullin-7 (1734 aa)
initn: 11398 init1: 8894 opt: 10081 Z-score: 10910.5 bits: 2031.9 E(85289): 0
Smith-Waterman score: 11333; 97.9% identity (97.9% similar) in 1734 aa overlap (1-1698:1-1734)
10 20 30 40 50 60
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
130 140 150 160 170 180
190 200
pF1KSD AGRMIQALSSHDAG--------------------------------TRTQILLSLSQQEA
:::::::::::::: ::::::::::::::
XP_006 AGRMIQALSSHDAGEGQCGEEGKAGEGLGRLRDSQDTVAGASDLIRTRTQILLSLSQQEA
190 200 210 220 230 240
210 220 230 240 250 260
pF1KSD IEKHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEKHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPGRVLFSLVKRYLHVTSLLDQLN
250 260 270 280 290 300
270 280 290 300 310 320
pF1KSD DSAAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISELVQAMRWDQASDRPRSSARSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSAAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISELVQAMRWDQASDRPRSSARSPG
310 320 330 340 350 360
330 340 350 360 370 380
pF1KSD SIFQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIFQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGNTYALYVRDTLQPGMRVRMLDD
370 380 390 400 410 420
390 400 410 420 430 440
pF1KSD YEEISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEEISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQG
430 440 450 460 470 480
450 460 470 480 490 500
pF1KSD AVASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECEHLTLAEWWELLFFIKKLDGPD
490 500 510 520 530 540
510 520 530 540 550 560
pF1KSD HQEVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HQEVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKY
550 560 570 580 590 600
570 580 590 600 610 620
pF1KSD GPEALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPEALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGY
610 620 630 640 650 660
630 640 650 660 670 680
pF1KSD GPAGKILLDLEQALSSEGTQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPAGKILLDLEQALSSEGTQENKVKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLR
670 680 690 700 710 720
690 700 710 720 730 740
pF1KSD ILKQLVDFPEALLLPWHEAVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILKQLVDFPEALLLPWHEAVDACMACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQ
730 740 750 760 770 780
750 760 770 780 790 800
pF1KSD LGARDAISKALEKHLGKLELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGARDAISKALEKHLGKLELAQELRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDH
790 800 810 820 830 840
810 820 830 840 850 860
pF1KSD RRTHRPINIPFFDVFLRYLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESN
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRTHQPINIPFFDVFLRYLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESN
850 860 870 880 890 900
870 880 890 900 910 920
pF1KSD GSAGSHYITLHMRRGILIRQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSAGSHYITLHMRRGILIRQLTLLVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPS
910 920 930 940 950 960
930 940 950 960 970 980
pF1KSD ASRVILLENLTRFWPIIQIRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASRVILLENLTRFWPIIQIRIKRCQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLF
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KSD YMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVS
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KSD PVVQNITSPDEDGISPLGWLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVVQNITSPDEDGISPLGWLLDQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEA
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KSD PPPVVATPRPKGRNRSHDWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPVVATPRPKGRNRSHDWSSLATRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDF
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KSD VPRYCEHFNILQNSSSELFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPRYCEHFNILQNSSSELFGPRAAFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQI
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KSD QGSRIGGAQEMERLAQLQQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGSRIGGAQEMERLAQLQQCLQAVLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAV
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KSD LEQIGPCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEQIGPCFPNRLPQQMLQSLSTSKELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASG
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KSD KEHKSEKEEEAGAAAVVDVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEHKSEKEEEAGAAAVVDVAEGEEEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTL
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KSD NPRTCLPSYLRGTLNRYSNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NPRTCLPSYLRGTLNRYSNFYNKSQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTV
1450 1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KSD QMWLLLYLNDLKAVSVESLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIPG----GV
:::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_006 QMWLLLYLNDLKAVSVESLLAFSGLSADMLNQAIGPLTSSRGPLDLHEQKDIPGAFISGV
1510 1520 1530 1540 1550 1560
1530 1540 1550 1560 1570 1580
pF1KSD LKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLH
1570 1580 1590 1600 1610 1620
1590 1600 1610 1620 1630 1640
pF1KSD IDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVL
1630 1640 1650 1660 1670 1680
1650 1660 1670 1680 1690
pF1KSD SYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQIRSRGVPYASCTATQSFSTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQIRSRGVPYASCTATQSFSTFR
1690 1700 1710 1720 1730
>>XP_011513321 (OMIM: 273750,609577) PREDICTED: cullin-7 (1786 aa)
initn: 11398 init1: 8894 opt: 10081 Z-score: 10910.3 bits: 2031.9 E(85289): 0
Smith-Waterman score: 11333; 97.9% identity (97.9% similar) in 1734 aa overlap (1-1698:53-1786)
10 20 30
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRV
::::::::::::::::::::::::::::::
XP_011 ADSRGCSSVPRRHAPSRLSVSTPSRGPGARMVGELRYREFRVPLGPGLHAYPDELIRQRV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KSD GHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KSD PSQESAGEVGALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSQESAGEVGALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASI
150 160 170 180 190 200
160 170 180 190
pF1KSD EPLTGVFKDPRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAG----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPLTGVFKDPRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAGEGQCGEEGKAGEGLGR
210 220 230 240 250 260
200 210 220 230
pF1KSD ----------------TRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFE
::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDSQDTVAGASDLIRTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFE
270 280 290 300 310 320
240 250 260 270 280 290
pF1KSD GIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIQLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSM
330 340 350 360 370 380
300 310 320 330 340 350
pF1KSD AMGTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMGTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFR
390 400 410 420 430 440
360 370 380 390 400 410
pF1KSD PRSEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTG
450 460 470 480 490 500
420 430 440 450 460 470
pF1KSD RTYWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTYWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLP
510 520 530 540 550 560
480 490 500 510 520 530
pF1KSD EDEDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDEDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIE
570 580 590 600 610 620
540 550 560 570 580 590
pF1KSD LAQDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQA
630 640 650 660 670 680
600 610 620 630 640 650
pF1KSD KDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQ
690 700 710 720 730 740
660 670 680 690 700 710
pF1KSD LQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSP
750 760 770 780 790 800
720 730 740 750 760 770
pF1KSD NTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFK
810 820 830 840 850 860
780 790 800 810 820 830
pF1KSD CEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHRPINIPFFDVFLRYLCQGSSVEVKED
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_011 CEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRYLCQGSSVEVKED
870 880 890 900 910 920
840 850 860 870 880 890
pF1KSD KCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDS
930 940 950 960 970 980
900 910 920 930 940 950
pF1KSD SYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGID
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KSD TRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGAL
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KSD RQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEA
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KSD VFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSS
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KSD IMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQ
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KSD NGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGL
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KSD EIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQF
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KSD HVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENE
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KSD DLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPAL
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KSD ERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADML
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KSD NQAIGPLTSSRGPLDLHEQKDIPG----GVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEG
:::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 NQAIGPLTSSRGPLDLHEQKDIPGAFISGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEG
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KSD EDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGS
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KSD ACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFH
1710 1720 1730 1740 1750 1760
1680 1690
pF1KSD TLQIRSRGVPYASCTATQSFSTFR
::::::::::::::::::::::::
XP_011 TLQIRSRGVPYASCTATQSFSTFR
1770 1780
>>XP_016867023 (OMIM: 273750,609577) PREDICTED: cullin-7 (1791 aa)
initn: 9201 init1: 7889 opt: 7889 Z-score: 8535.5 bits: 1592.5 E(85289): 0
Smith-Waterman score: 11264; 97.6% identity (97.6% similar) in 1730 aa overlap (10-1698:62-1791)
10 20 30
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQ
::::::::::::::::::::::::::::::
XP_016 PRRHAPSRLSVSTPSRGPGARMVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQ
40 50 60 70 80 90
40 50 60 70 80 90
pF1KSD IRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEV
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD GALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GALDKSVLEEMETDVKSLIQRALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKD
160 170 180 190 200 210
160 170 180 190
pF1KSD PRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAG-------------------------
:::::::::::::::::::::::::::::::::::
XP_016 PRVLDLLMHMLSSPDYQIRWSAGRMIQALSSHDAGEGQCGEEGKAGEGLGRLRDSQDTVA
220 230 240 250 260 270
200 210 220 230 240
pF1KSD -------TRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASDLIRTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGIQLPQVPG
280 290 300 310 320 330
250 260 270 280 290 300
pF1KSD RVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAMGTLISEL
340 350 360 370 380 390
310 320 330 340 350 360
pF1KSD VQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPRSEFASGN
400 410 420 430 440 450
370 380 390 400 410 420
pF1KSD TYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRTYWVHWHM
460 470 480 490 500 510
430 440 450 460 470 480
pF1KSD LEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPEDEDTEECE
520 530 540 550 560 570
490 500 510 520 530
pF1KSD HLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGE---------ILDDEILAELAVPIE
:::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 HLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEVEPAWRHSEILDDEILAELAVPIE
580 590 600 610 620 630
540 550 560 570 580 590
pF1KSD LAQDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQA
640 650 660 670 680 690
600 610 620 630 640 650
pF1KSD KDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQ
700 710 720 730 740 750
660 670 680 690 700 710
pF1KSD LQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSP
760 770 780 790 800 810
720 730 740 750 760 770
pF1KSD NTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFK
820 830 840 850 860 870
780 790 800 810 820 830
pF1KSD CEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHRPINIPFFDVFLRYLCQGSSVEVKED
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 CEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRYLCQGSSVEVKED
880 890 900 910 920 930
840 850 860 870 880 890
pF1KSD KCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDS
940 950 960 970 980 990
900 910 920 930 940 950
pF1KSD SYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGID
1000 1010 1020 1030 1040 1050
960 970 980 990 1000 1010
pF1KSD TRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGAL
1060 1070 1080 1090 1100 1110
1020 1030 1040 1050 1060 1070
pF1KSD RQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEA
1120 1130 1140 1150 1160 1170
1080 1090 1100 1110 1120 1130
pF1KSD VFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSS
1180 1190 1200 1210 1220 1230
1140 1150 1160 1170 1180 1190
pF1KSD IMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQ
1240 1250 1260 1270 1280 1290
1200 1210 1220 1230 1240 1250
pF1KSD NGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGL
1300 1310 1320 1330 1340 1350
1260 1270 1280 1290 1300 1310
pF1KSD EIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQF
1360 1370 1380 1390 1400 1410
1320 1330 1340 1350 1360 1370
pF1KSD HVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENE
1420 1430 1440 1450 1460 1470
1380 1390 1400 1410 1420 1430
pF1KSD DLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPAL
1480 1490 1500 1510 1520 1530
1440 1450 1460 1470 1480 1490
pF1KSD ERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADML
1540 1550 1560 1570 1580 1590
1500 1510 1520 1530 1540 1550
pF1KSD NQAIGPLTSSRGPLDLHEQKDIPGGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQAIGPLTSSRGPLDLHEQKDIPGGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQ
1600 1610 1620 1630 1640 1650
1560 1570 1580 1590 1600 1610
pF1KSD NLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSS
1660 1670 1680 1690 1700 1710
1620 1630 1640 1650 1660 1670
pF1KSD TDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQI
1720 1730 1740 1750 1760 1770
1680 1690
pF1KSD RSRGVPYASCTATQSFSTFR
::::::::::::::::::::
XP_016 RSRGVPYASCTATQSFSTFR
1780 1790
>>XP_016867027 (OMIM: 273750,609577) PREDICTED: cullin-7 (1711 aa)
initn: 11408 init1: 6684 opt: 7871 Z-score: 8516.2 bits: 1588.8 E(85289): 0
Smith-Waterman score: 11379; 99.2% identity (99.2% similar) in 1711 aa overlap (1-1698:1-1711)
10 20 30 40 50 60
pF1KSD MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD GTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD YWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPED
430 440 450 460 470 480
490 500 510 520 530
pF1KSD EDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGE---------ILDDEILA
::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 EDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEVEPAWRHSEILDDEILA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD ELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD LDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDAQAQAKDSEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD VKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKPLLLQLQRQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDAC
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD MACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MACLRSPNTDREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQE
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD LRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHRPINIPFFDVFLRYLCQGS
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 LRDMVFKCEKHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRYLCQGS
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD SVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD LVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVASEDSSYMPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKR
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD CQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQQGGIDTRIRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLS
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD SRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLNGALRQEQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQ
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KSD YLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLA
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KSD TRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRGLPSSIMRNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRA
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KSD AFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFLLALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQA
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KSD VLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLIFSGLEIATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTS
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KSD KELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELQRQFHVYQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGE
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KSD EEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEENEDLYYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNK
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KSD SQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSHPALERGSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFS
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540
pF1KSD GLSADMLNQAIGPLTSSRGPLDLHEQKDIPG----GVLKIRDGSKEPRSRWDIVRLIPPQ
::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 GLSADMLNQAIGPLTSSRGPLDLHEQKDIPGAFISGVLKIRDGSKEPRSRWDIVRLIPPQ
1510 1520 1530 1540 1550 1560
1550 1560 1570 1580 1590 1600
pF1KSD TYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYLQAEGEDGQNLEKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLV
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KSD SSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLGKGSACSSTDVLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGP
1630 1640 1650 1660 1670 1680
1670 1680 1690
pF1KSD NPPLTFHTLQIRSRGVPYASCTATQSFSTFR
:::::::::::::::::::::::::::::::
XP_016 NPPLTFHTLQIRSRGVPYASCTATQSFSTFR
1690 1700 1710
1698 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:49:41 2016 done: Wed Nov 2 23:49:43 2016
Total Scan time: 18.610 Total Display time: 1.020
Function used was FASTA [36.3.4 Apr, 2011]