Result of FASTA (ccds) for
pFN21AB8019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8019, 670 aa
1>>>pF1KB8019 670 - 670 aa - 670 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7071+/-0.00101; mu= 2.3715+/- 0.061
mean_var=323.9418+/-66.157, 0's: 0 Z-trim(114.8): 17 B-trim: 165 in 1/54
Lambda= 0.071259
statistics sampled from 15303 (15316) to 15303 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.47), width: 16
Scan time: 4.120
The best scores are: opt bits E(32554)
CCDS22.1 DVL1 gene_id:1855|Hs108|chr1 ( 670) 4518 478.4 1.4e-134
CCDS81252.1 DVL1 gene_id:1855|Hs108|chr1 ( 695) 2504 271.4 3e-72
CCDS3253.1 DVL3 gene_id:1857|Hs108|chr3 ( 716) 1868 206.0 1.5e-52
CCDS11091.1 DVL2 gene_id:1856|Hs108|chr17 ( 736) 1682 186.9 8.7e-47
>>CCDS22.1 DVL1 gene_id:1855|Hs108|chr1 (670 aa)
initn: 4518 init1: 4518 opt: 4518 Z-score: 2529.7 bits: 478.4 E(32554): 1.4e-134
Smith-Waterman score: 4518; 100.0% identity (100.0% similar) in 670 aa overlap (1-670:1-670)
10 20 30 40 50 60
pF1KB8 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 AAWLSHTAALTGALPRYELEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 AAWLSHTAALTGALPRYELEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 IGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 IGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 TLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 TLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGST
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 GSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 RGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMG
610 620 630 640 650 660
670
pF1KB8 NPCEFFVDIM
::::::::::
CCDS22 NPCEFFVDIM
670
>>CCDS81252.1 DVL1 gene_id:1855|Hs108|chr1 (695 aa)
initn: 4500 init1: 2500 opt: 2504 Z-score: 1410.5 bits: 271.4 E(32554): 3e-72
Smith-Waterman score: 4454; 96.3% identity (96.4% similar) in 695 aa overlap (1-670:1-695)
10 20 30 40 50 60
pF1KB8 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
310 320 330 340 350 360
370 380 390
pF1KB8 AAWLSHTAALTGALPRY-------------------------ELEEAPLTVKSDMSAVVR
::::::::::::::::: .:::::::::::::::::
CCDS81 AAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAVVR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB8 VMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB8 RHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPY
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB8 QYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB8 GSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGG
610 620 630 640 650 660
640 650 660 670
pF1KB8 PPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM
:::::::::::::::::::::::::::::::::::
CCDS81 PPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM
670 680 690
>>CCDS3253.1 DVL3 gene_id:1857|Hs108|chr3 (716 aa)
initn: 1993 init1: 1198 opt: 1868 Z-score: 1057.0 bits: 206.0 E(32554): 1.5e-52
Smith-Waterman score: 2822; 63.8% identity (81.4% similar) in 709 aa overlap (1-654:1-700)
10 20 30 40 50 60
pF1KB8 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
:.:::::::.: .:::::::::. :::::::::.::. :: .:::::::::.::::::
CCDS32 MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQ-RP--SYKFFFKSMDDDFGVVK
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
::: :::::::::::::::::: :::.: : . .:. ..::::.::::::::::::::
CCDS32 EEISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSF
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 HPNVAS-SRDGMDNETGTESMVSHRRERARRRNR-EEAARTNGHPRGDRRRDVGLPPDSA
::.... :....::.: :.:.:: .::: :::. :.:.: :: .:.:::. : ::.
CCDS32 HPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPG-GYDSS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 STALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFS
:: .:::::..:: ::::: ::::.:::::::..:::.:.::::::::.. . .:.::::
CCDS32 STLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 SITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPG
:::::::::::.:::::::...:::::::::::.::::::::::::::::::::::::::
CCDS32 SITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 DMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPI
:::::::..:::::::::::::::::: . :::.:::::::::.::. ::.::..:.:::
CCDS32 DMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPI
300 310 320 330 340 350
360 370 380 390
pF1KB8 DPAAWLSHTAALTGALPRY------------------------ELEEAPLTVKSDMSAVV
:::::.:::::.::..: : .:.. :...:::.:.:
CCDS32 DPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB8 RVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGF
..: :.::::.:::::::::: :: ::.::::::: .:::: .:::::::::.::: ::
CCDS32 KAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGF
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB8 LRHTVNKITFSEQCYYVFGDLCSNLATLNLNS--GSSGTSDQDTLAPLPHP-AAPWPLGQ
.:::::::::::::::.:::::.:.:.:.:.. ::::.:::::::::::: :::::..
CCDS32 IRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMA-
480 490 500 510 520 530
520 530 540 550 560
pF1KB8 GYPYQYPGPP-PCFP-PAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSS--RRAPGREKER
.::::: :: : : :.. . :.:::.::..::.::::.::::.::. :: .::.
CCDS32 -FPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRR---KEKDP
540 550 560 570 580 590
570 580 590 600
pF1KB8 RAAGA--GGSGSESDHTAPSGV------GSSWRERPAG-------QLSRGSSPRSQ---A
.:. . ::::::::::. :.. . : : ::. . : .:: ::.
CCDS32 KAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHP
600 610 620 630 640 650
610 620 630 640 650 660
pF1KB8 SATAPGLPP----PHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEF
: ::.:: : .. ::::.:: :.::.::::::.::::
CCDS32 SYGPPGVPPLYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEF
660 670 680 690 700 710
670
pF1KB8 FVDIM
CCDS32 FVDVM
>>CCDS11091.1 DVL2 gene_id:1856|Hs108|chr17 (736 aa)
initn: 1782 init1: 1135 opt: 1682 Z-score: 953.5 bits: 186.9 E(32554): 8.7e-47
Smith-Waterman score: 2543; 59.3% identity (77.5% similar) in 717 aa overlap (1-652:11-718)
10 20 30 40 50
pF1KB8 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFK
..:::.:::.::::::::::.:: ::.::.:::.::. ::. : :.:::
CCDS11 MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQ-RPAGA-KYFFK
10 20 30 40 50
60 70 80 90 100
pF1KB8 SMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPL----
::::::::::::: ::::.::::::::::::: ... . . . . ...: ::
CCDS11 SMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLP
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 ----ERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNREE---AART
:::.::::::::::::::.::..... :: :::.:: :::: :::. : ...
CCDS11 PLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHR
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 NGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKH
.: : .:. .: .:.:: ..:::::.:. ::::. . ::.:::::::..:::...:
CCDS11 TGGPSRLERHLAGY--ESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRH
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 KRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIY
::::::: . .:.:::::.:::::::::.:::::::...:::::::::::.:::::::
CCDS11 -RRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIY
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB8 IGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCW
:::::::::::::::::::::::::::.:::::::::::::::.:: . ::: :::::::
CCDS11 IGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCW
300 310 320 330 340 350
340 350 360 370 380
pF1KB8 DPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYE-----------------LEEA
::.:..:::.:: .:..:::::::.::.:::::..: : :
CCDS11 DPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGR
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB8 PLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREA
:.:..::..:...: :.::::.:::::::::: :: .:.::::::: ::::: :::::
CCDS11 GLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREA
420 430 440 450 460 470
450 460 470 480 490
pF1KB8 RKYASSLLKHGFLRHTVNKITFSEQCYYVFGDL---C-SNLATLNLNS--GSSGTSDQDT
:::::.::: :..:::::::::::::::::::: : : :..:.::. ::::.:::::
CCDS11 RKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDT
480 490 500 510 520 530
500 510 520 530 540 550
pF1KB8 LAPLPHPAAPWPLGQGYPYQYPGPPPCFP--PAYQD-PGFSYGSGSTGSQQSEGSKSSGS
::::: :.:::: . ::::.: : : : :.. ...::.::..::.::::.::::
CCDS11 LAPLPG-ATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGS
540 550 560 570 580 590
560 570 580 590 600 610
pF1KB8 TRSSRRA--PGREKERRAAGAGGSGSESDHTAPSGVGSSWRER-PAGQLSRGSSPRSQAS
:::. : :: .:: . .::::::. ::. :.: :. :. : :. : :..:
CCDS11 TRSDGGAGRTGRPEERAPESKSGSGSESE---PSSRGGSLRRGGEASGTSDGGPPPSRGS
600 610 620 630 640 650
620 630 640
pF1KB8 ATA-------PGL----PPPH---PTTKAYTVVGGPP-----------GGPPVRELAAVP
. . ::: ::: : . ..:. :: :.::::.:..::
CCDS11 TGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVP
660 670 680 690 700 710
650 660 670
pF1KB8 PELTGSRQSFQKAMGNPCEFFVDIM
::::.::
CCDS11 PELTASRQSFHMAMGNPSEFFVDVM
720 730
670 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:16:05 2016 done: Wed Nov 2 23:16:05 2016
Total Scan time: 4.120 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]