Result of FASTA (omim) for
pFN21AB8017
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8017, 647 aa
1>>>pF1KB8017 647 - 647 aa - 647 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.9354+/-0.000555; mu= -10.5529+/- 0.034
mean_var=831.4968+/-187.550, 0's: 0 Z-trim(120.2): 658 B-trim: 0 in 0/57
Lambda= 0.044478
statistics sampled from 34348 (35225) to 34348 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.413), width: 16
Scan time: 11.730
The best scores are: opt bits E(85289)
NP_002305 (OMIM: 601329) LIM domain kinase 1 isofo ( 647) 4556 308.9 3.8e-83
NP_001191355 (OMIM: 601329) LIM domain kinase 1 is ( 613) 4177 284.5 7.7e-76
NP_057952 (OMIM: 601988) LIM domain kinase 2 isofo ( 617) 1503 112.9 3.5e-24
NP_005560 (OMIM: 601988) LIM domain kinase 2 isofo ( 638) 1503 112.9 3.5e-24
NP_001026971 (OMIM: 601988) LIM domain kinase 2 is ( 686) 1426 108.0 1.1e-22
NP_006276 (OMIM: 601782) dual specificity testis-s ( 626) 661 58.9 6.4e-08
XP_016855537 (OMIM: 604746) PREDICTED: dual specif ( 363) 408 42.3 0.0037
XP_016855538 (OMIM: 604746) PREDICTED: dual specif ( 363) 408 42.3 0.0037
NP_001307729 (OMIM: 604746) dual specificity testi ( 488) 410 42.6 0.004
XP_005270412 (OMIM: 604746) PREDICTED: dual specif ( 522) 410 42.7 0.0041
XP_016855536 (OMIM: 604746) PREDICTED: dual specif ( 522) 410 42.7 0.0041
XP_006710350 (OMIM: 604746) PREDICTED: dual specif ( 571) 410 42.7 0.0043
XP_011538799 (OMIM: 604746) PREDICTED: dual specif ( 571) 410 42.7 0.0043
NP_009101 (OMIM: 604746) dual specificity testis-s ( 571) 410 42.7 0.0043
NP_001305159 (OMIM: 601782) dual specificity testi ( 466) 405 42.3 0.0048
XP_011541578 (OMIM: 176942) PREDICTED: tyrosine-pr ( 468) 398 41.8 0.0066
XP_016864722 (OMIM: 176942) PREDICTED: tyrosine-pr ( 764) 398 42.2 0.0086
XP_011541574 (OMIM: 176942) PREDICTED: tyrosine-pr ( 769) 398 42.2 0.0086
XP_016864721 (OMIM: 176942) PREDICTED: tyrosine-pr ( 773) 398 42.2 0.0087
XP_011541572 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 398 42.2 0.009
XP_011541568 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 398 42.2 0.009
XP_016864718 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 398 42.2 0.009
XP_011541571 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 398 42.2 0.009
XP_011541569 (OMIM: 176942) PREDICTED: tyrosine-pr ( 837) 398 42.2 0.009
>>NP_002305 (OMIM: 601329) LIM domain kinase 1 isoform 1 (647 aa)
initn: 4556 init1: 4556 opt: 4556 Z-score: 1613.8 bits: 308.9 E(85289): 3.8e-83
Smith-Waterman score: 4556; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KB8 MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 HQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEID
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LLIQETSRLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLIQETSRLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 RSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 TGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 EIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL
550 560 570 580 590 600
610 620 630 640
pF1KB8 EHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD
:::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD
610 620 630 640
>>NP_001191355 (OMIM: 601329) LIM domain kinase 1 isofor (613 aa)
initn: 4177 init1: 4177 opt: 4177 Z-score: 1482.5 bits: 284.5 E(85289): 7.7e-76
Smith-Waterman score: 4177; 99.8% identity (100.0% similar) in 597 aa overlap (51-647:17-613)
30 40 50 60 70 80
pF1KB8 ELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARY
.:::::::::::::::::::::::::::::
NP_001 MLLASAPRRRRFLQRAKCCDCSASLSHQYYEKDGQLFCKKDYWARY
10 20 30 40
90 100 110 120 130 140
pF1KB8 GESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQ
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB8 TVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVR
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB8 VQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHD
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB8 TLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGR
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB8 SESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRT
290 300 310 320 330 340
390 400 410 420 430 440
pF1KB8 FLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSF
350 360 370 380 390 400
450 460 470 480 490 500
pF1KB8 AKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKK
410 420 430 440 450 460
510 520 530 540 550 560
pF1KB8 PDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG
470 480 490 500 510 520
570 580 590 600 610 620
pF1KB8 LNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQ
530 540 550 560 570 580
630 640
pF1KB8 LEQLDRGFWETYRRGESGLPAHPEVPD
:::::::::::::::::::::::::::
NP_001 LEQLDRGFWETYRRGESGLPAHPEVPD
590 600 610
>>NP_057952 (OMIM: 601988) LIM domain kinase 2 isoform 2 (617 aa)
initn: 2174 init1: 578 opt: 1503 Z-score: 555.2 bits: 112.9 E(85289): 3.5e-24
Smith-Waterman score: 2238; 55.7% identity (78.2% similar) in 610 aa overlap (35-625:2-602)
10 20 30 40 50 60
pF1KB8 LLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYY
:.::.. : ::: .:. ::.. ::
NP_057 MGSYLSVPAYFTSRDLFRCSECQDSLTNWYY
10 20 30
70 80 90 100 110 120
pF1KB8 EKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTY
::::.:.: ::::...:: ::::: .: : :::::.::::::: :..: ..: :::.:
NP_057 EKDGKLYCPKDYWGKFGEFCHGCSLLMT-GPFMVAGEFKYHPECFACMSCKVIIEDGDAY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 TLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDP
.::.:. ::::.:. ..:..:..:.. .: .::..:::.:.::...:.::.:::..
NP_057 ALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMPATTEGRRGFSVSVES
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 PHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQ
.: .... ::.:. :. .::. .:.:: :::::::::::.:.. ..:.. :.
NP_057 -----AC-SNYATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAIS
160 170 180 190 200
250 260 270 280 290
pF1KB8 ETSRLLQLTLEHDP------HDTLGHGLGPETSPLSSPAYTPSGEAG----SSARQKPVL
.::. ::: .:::: . : :.:. . . : . .. .. :.. .
NP_057 QTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLRRRSLR
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB8 RSCSIDRSPGAGSLGSPASQRKDLGRSESLRVVCR-PHRIFRPSDLIHGEVLGKGCFGQA
:: ::..::: .: : .:..:::::: ..:::: ::::::::::: ::::
NP_057 RSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQA
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB8 IKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFIT
:::::. ::.::::::::: :::::.::: :::::: :.:::::::::::::::.::..:
NP_057 IKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLT
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB8 EYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKN
:::.::::. ...::: .::.:.: ::: ::::::::::: ::::::::::::.. .:.
NP_057 EYIEGGTLKDFLRSMDP-FPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKT
390 400 410 420 430 440
480 490 500 510 520
pF1KB8 VVVADFGLARLMVDE-KTQP-----EGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYD
::::::::.::.:.: : : :.:.: :::::::::::::::::::.::.:::
NP_057 VVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYD
450 460 470 480 490 500
530 540 550 560 570 580
pF1KB8 EKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCC
: ::.::::::::::::.: :::: ::::.::::::. : ... : .:::.:::... ::
NP_057 ETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICC
510 520 530 540 550 560
590 600 610 620 630 640
pF1KB8 DLDPEKRPSFVKLEHWLETLRMHLAGHL--PLGPQLEQLDRGFWETYRRGESGLPAHPEV
:.::.::.: ::: .:.: ..: :.: :: .::.::
NP_057 RLEPESRPAFSKLEDSFEALSLYL-GELGIPLPAELEELDHTVSMQYGLTRDSPP
570 580 590 600 610
pF1KB8 PD
>>NP_005560 (OMIM: 601988) LIM domain kinase 2 isoform 2 (638 aa)
initn: 2186 init1: 578 opt: 1503 Z-score: 555.1 bits: 112.9 E(85289): 3.5e-24
Smith-Waterman score: 2308; 55.2% identity (78.5% similar) in 627 aa overlap (19-625:6-623)
10 20 30 40 50
pF1KB8 MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQ-YLQALNADWHADCFRCCDCSASL
: .. : .::..: .: . ...: ::..:::: .:. ::
NP_005 MSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRCSECQDSL
10 20 30 40
60 70 80 90 100 110
pF1KB8 SHQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIG
.. ::::::.:.: ::::...:: ::::: .: : :::::.::::::: :..: ..:
NP_005 TNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMT-GPFMVAGEFKYHPECFACMSCKVIIE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB8 DGDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLS
:::.:.::.:. ::::.:. ..:..:..:.. .: .::..:::.:.::...:.::.:
NP_005 DGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMPATTEGRRGFS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 VSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEI
::.. .: .... ::.:. :. .::. .:.:: :::::::::::.:.. ..:.
NP_005 VSVE-----SAC-SNYATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEV
170 180 190 200 210 220
240 250 260 270 280
pF1KB8 DLLIQETSRLLQLTLEHDP------HDTLGHGLGPETSPLSSPAYTPSGEAG----SSAR
. :..::. ::: .:::: . : :.:. . . : . .. .. :
NP_005 EDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLR
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 QKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESLRVVCR-PHRIFRPSDLIHGEVLGKG
.. . :: ::..::: .: : .:..:::::: ..:::: :::::::::::
NP_005 RRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKG
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB8 CFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKR
:::::::::. ::.::::::::: :::::.::: :::::: :.:::::::::::::::.
NP_005 FFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKK
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB8 LNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLV
::..::::.::::. ...::: .::.:.: ::: ::::::::::: ::::::::::::.
NP_005 LNLLTEYIEGGTLKDFLRSMDP-FPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLI
410 420 430 440 450
470 480 490 500 510 520
pF1KB8 RENKNVVVADFGLARLMVDE-KTQP-----EGLRSLKKPDRKKRYTVVGNPYWMAPEMIN
. .:.::::::::.::.:.: : : :.:.: :::::::::::::::::::.:
NP_005 KLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLN
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB8 GRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPI
:.:::: ::.::::::::::::.: :::: ::::.::::::. : ... : .:::.:::.
NP_005 GKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPL
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB8 TVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHL--PLGPQLEQLDRGFWETYRRGESGLP
.. :: :.::.::.: ::: .:.: ..: :.: :: .::.::
NP_005 AAICCRLEPESRPAFSKLEDSFEALSLYL-GELGIPLPAELEELDHTVSMQYGLTRDSPP
580 590 600 610 620 630
pF1KB8 AHPEVPD
>>NP_001026971 (OMIM: 601988) LIM domain kinase 2 isofor (686 aa)
initn: 2091 init1: 523 opt: 1426 Z-score: 528.0 bits: 108.0 E(85289): 1.1e-22
Smith-Waterman score: 2161; 56.2% identity (78.5% similar) in 577 aa overlap (35-594:2-570)
10 20 30 40 50 60
pF1KB8 LLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYY
:.::.. : ::: .:. ::.. ::
NP_001 MGSYLSVPAYFTSRDLFRCSECQDSLTNWYY
10 20 30
70 80 90 100 110 120
pF1KB8 EKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTY
::::.:.: ::::...:: ::::: .: : :::::.::::::: :..: ..: :::.:
NP_001 EKDGKLYCPKDYWGKFGEFCHGCSLLMT-GPFMVAGEFKYHPECFACMSCKVIIEDGDAY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 TLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDP
.::.:. ::::.:. ..:..:..:.. .: .::..:::.:.::...:.::.:::..
NP_001 ALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMPATTEGRRGFSVSVES
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 PHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQ
.: .... ::.:. :. .::. .:.:: :::::::::::.:.. ..:.. :.
NP_001 -----AC-SNYATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAIS
160 170 180 190 200
250 260 270 280 290
pF1KB8 ETSRLLQLTLEHDP------HDTLGHGLGPETSPLSSPAYTPSGEAG----SSARQKPVL
.::. ::: .:::: . : :.:. . . : . .. .. :.. .
NP_001 QTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLRRRSLR
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB8 RSCSIDRSPGAGSLGSPASQRKDLGRSESLRVVCR-PHRIFRPSDLIHGEVLGKGCFGQA
:: ::..::: .: : .:..:::::: ..:::: ::::::::::: ::::
NP_001 RSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQA
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB8 IKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFIT
:::::. ::.::::::::: :::::.::: :::::: :.:::::::::::::::.::..:
NP_001 IKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLT
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB8 EYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKN
:::.::::. ...::: .::.:.: ::: ::::::::::: ::::::::::::.. .:.
NP_001 EYIEGGTLKDFLRSMDP-FPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKT
390 400 410 420 430 440
480 490 500 510 520
pF1KB8 VVVADFGLARLMVDE-KTQP-----EGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYD
::::::::.::.:.: : : :.:.: :::::::::::::::::::.::.:::
NP_001 VVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYD
450 460 470 480 490 500
530 540 550 560 570 580
pF1KB8 EKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCC
: ::.::::::::::::.: :::: ::::.::::::. : ... : .:::.:::... ::
NP_001 ETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICC
510 520 530 540 550 560
590 600 610 620 630 640
pF1KB8 DLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD
:.::.:
NP_001 RLEPESRAPPGAAGEGPGCADDEGPVRRQGKVTIKYDPKELRKHLNLEEWILEQLTRLYD
570 580 590 600 610 620
>>NP_006276 (OMIM: 601782) dual specificity testis-speci (626 aa)
initn: 731 init1: 319 opt: 661 Z-score: 263.1 bits: 58.9 E(85289): 6.4e-08
Smith-Waterman score: 778; 40.2% identity (65.9% similar) in 346 aa overlap (303-644:24-349)
280 290 300 310 320 330
pF1KB8 LSSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESLRVVCRP-H
:: :. :. .. :: : :..
NP_006 MAGERPPLRGPGPGPGEVPGEGPPGPGGTGGGPGR----GRPSSYRALRSAVS
10 20 30 40
340 350 360 370 380 390
pF1KB8 RIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCL
. : .:. .: .: : :... :: ::..:.:::.: . .. . : :.::..: :
NP_006 SLARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLK-MNKLPSNRGNT-LREVQLMNRL
50 60 70 80 90 100
400 410 420 430 440 450
pF1KB8 EHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYL
.:::.:.:.:: .. .:. .:::..::::. ...: . : :. .: ::: :. ::
NP_006 RHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP-LSWPVRLHLALDIARGLRYL
110 120 130 140 150 160
460 470 480 490 500
pF1KB8 HSMNIIHRDLNSHNCLVR-ENKN--VVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYT
:: ...::::.:.::::: :... .::.::::: : . .. ::. .
NP_006 HSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLA----------EKIPVYREGARKEPLA
170 180 190 200 210
510 520 530 540 550 560
pF1KB8 VVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLD
:::.:::::::.. :. ::::.:::.:::::::.:.:: ::::::::: ::::.: .:
NP_006 VVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAF-R
220 230 240 250 260 270
570 580 590 600 610 620
pF1KB8 RYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGF
.:: :. ....::.:.: : :... . :: . .: :: ..:
NP_006 TLVGDDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEPAPLTRTALTHNQG-
280 290 300 310 320 330
630 640
pF1KB8 WETYRRGESGLPAHPEVPD
. : : :. .:.
NP_006 -SVARGGPSATLPRPDPRLSRSRSDLFLPPSPESPPNWGDNLTRVNPFSLREDLRGGKIK
340 350 360 370 380 390
>>XP_016855537 (OMIM: 604746) PREDICTED: dual specificit (363 aa)
initn: 407 init1: 284 opt: 408 Z-score: 177.6 bits: 42.3 E(85289): 0.0037
Smith-Waterman score: 408; 51.5% identity (81.6% similar) in 103 aa overlap (505-607:4-104)
480 490 500 510 520 530
pF1KB8 VVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFS
.. .:::.:.:::::.. . :.::.::::
XP_016 MGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFS
10 20 30
540 550 560 570 580 590
pF1KB8 FGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKR
.::.:::::.:..::::::::: .:::. .: .. .:::.:. .: ::..::. :
XP_016 YGIILCEIIARIQADPDYLPRTENFGLDYDAF--QHMVGDCPPDFLQLTFNCCNMDPKLR
40 50 60 70 80 90
600 610 620 630 640
pF1KB8 PSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD
::::.. . :: .
XP_016 PSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPR
100 110 120 130 140 150
>>XP_016855538 (OMIM: 604746) PREDICTED: dual specificit (363 aa)
initn: 407 init1: 284 opt: 408 Z-score: 177.6 bits: 42.3 E(85289): 0.0037
Smith-Waterman score: 408; 51.5% identity (81.6% similar) in 103 aa overlap (505-607:4-104)
480 490 500 510 520 530
pF1KB8 VVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFS
.. .:::.:.:::::.. . :.::.::::
XP_016 MGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFS
10 20 30
540 550 560 570 580 590
pF1KB8 FGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKR
.::.:::::.:..::::::::: .:::. .: .. .:::.:. .: ::..::. :
XP_016 YGIILCEIIARIQADPDYLPRTENFGLDYDAF--QHMVGDCPPDFLQLTFNCCNMDPKLR
40 50 60 70 80 90
600 610 620 630 640
pF1KB8 PSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD
::::.. . :: .
XP_016 PSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPR
100 110 120 130 140 150
>>NP_001307729 (OMIM: 604746) dual specificity testis-sp (488 aa)
initn: 684 init1: 284 opt: 410 Z-score: 177.1 bits: 42.6 E(85289): 0.004
Smith-Waterman score: 702; 46.7% identity (75.1% similar) in 229 aa overlap (382-607:16-229)
360 370 380 390 400 410
pF1KB8 QAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNF
::::..: : :::.:.:.:: .. .:.
NP_001 MALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHA
10 20 30 40
420 430 440 450 460 470
pF1KB8 ITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVREN
.::::..:.:. .. : . . ::. ::..: ::: :..::: .:.::::.:.:::....
NP_001 LTEYINSGNLEQLLDS-NLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRD
50 60 70 80 90 100
480 490 500 510 520
pF1KB8 KN---VVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDE
.: .::::::::. . : . : : .:::.:.:::::.. . :.:
NP_001 ENGYSAVVADFGLAEKIPDVSMGSEKL------------AVVGSPFWMAPEVLRDEPYNE
110 120 130 140 150
530 540 550 560 570 580
pF1KB8 KVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCD
:.::::.::.:::::.:..::::::::: .:::. .: .. .:::.:. .: ::.
NP_001 KADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAF--QHMVGDCPPDFLQLTFNCCN
160 170 180 190 200 210
590 600 610 620 630 640
pF1KB8 LDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD
.::. :::::.. . :: .
NP_001 MDPKLRPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPH
220 230 240 250 260 270
>>XP_005270412 (OMIM: 604746) PREDICTED: dual specificit (522 aa)
initn: 619 init1: 284 opt: 410 Z-score: 176.8 bits: 42.7 E(85289): 0.0041
Smith-Waterman score: 520; 34.2% identity (58.0% similar) in 307 aa overlap (304-607:25-263)
280 290 300 310 320 330
pF1KB8 SSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESLRVVCRPHRI
:.:. :. .:: . : .. :.
XP_005 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGN-VSQVGRVWPSSYRALISAFSRL
10 20 30 40 50
340 350 360 370 380 390
pF1KB8 FRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEH
: .:. : .:.: :....:: :: .:.::..: . .. ..::::..: : :
XP_005 TRLDDFTC-EKIGSGFFSEVFKVRHRASGQVMALK--MNTLSSNRANMLKEVQLMNRLSH
60 70 80 90 100 110
400 410 420 430 440 450
pF1KB8 PNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHS
::.:.:.:: .. .:. .::
XP_005 PNILRFMGVCVHQGQLHALTE---------------------------------------
120 130
460 470 480 490 500 510
pF1KB8 MNIIHRDLNSHNCLVRENKN---VVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVV
:::.....: .::::::::. . : . : : .::
XP_005 -----------NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKL------------AVV
140 150 160
520 530 540 550 560 570
pF1KB8 GNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRY
:.:.:::::.. . :.::.::::.::.:::::.:..::::::::: .:::. .: ..
XP_005 GSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAF--QH
170 180 190 200 210 220
580 590 600 610 620 630
pF1KB8 CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWE
.:::.:. .: ::..::. :::::.. . :: .
XP_005 MVGDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLL
230 240 250 260 270 280
640
pF1KB8 TYRRGESGLPAHPEVPD
XP_005 EKAPGVKRLSSLDDKIPHKSPCPRRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAAR
290 300 310 320 330 340
647 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:15:23 2016 done: Wed Nov 2 23:15:25 2016
Total Scan time: 11.730 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]