Result of FASTA (ccds) for
pFN21AB4393
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4393, 1390 aa
1>>>pF1KB4393 1390 - 1390 aa - 1390 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9974+/-0.0012; mu= 14.4291+/- 0.072
mean_var=78.3007+/-16.339, 0's: 0 Z-trim(102.4): 14 B-trim: 390 in 1/47
Lambda= 0.144941
statistics sampled from 6946 (6950) to 6946 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.213), width: 16
Scan time: 4.070
The best scores are: opt bits E(32554)
CCDS7354.1 POLR3A gene_id:11128|Hs108|chr10 (1390) 9194 1932.9 0
CCDS42706.1 POLR1A gene_id:25885|Hs108|chr2 (1720) 485 111.7 1.8e-23
>>CCDS7354.1 POLR3A gene_id:11128|Hs108|chr10 (1390 aa)
initn: 9194 init1: 9194 opt: 9194 Z-score: 10378.6 bits: 1932.9 E(32554): 0
Smith-Waterman score: 9194; 100.0% identity (100.0% similar) in 1390 aa overlap (1-1390:1-1390)
10 20 30 40 50 60
pF1KB4 MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKCGLLKIIHEKYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKCGLLKIIHEKYK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENLNPLVVLNLFKRIPAEDVPLLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENLNPLVVLNLFKRIPAEDVPLLLM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 NPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 AKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 AKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 IQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 KPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 AIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 AIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 FSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 NNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 YKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 YKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTM
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 ALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 GLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 IYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 CQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 CQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 KYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB4 STPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 STPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB4 RLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB4 VQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGI
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB4 EAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLAS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB4 FEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPKRPLIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPKRPLIFD
1330 1340 1350 1360 1370 1380
1390
pF1KB4 TNEFHIPLVT
::::::::::
CCDS73 TNEFHIPLVT
1390
>>CCDS42706.1 POLR1A gene_id:25885|Hs108|chr2 (1720 aa)
initn: 1527 init1: 459 opt: 485 Z-score: 534.9 bits: 111.7 E(32554): 1.8e-23
Smith-Waterman score: 1421; 33.6% identity (59.0% similar) in 921 aa overlap (310-1118:391-1298)
280 290 300 310 320 330
pF1KB4 TMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTR
: :: . . ..::.. . .. :
CCDS42 DEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYP-----
370 380 390 400 410
340 350 360 370 380 390
pF1KB4 GFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKA
:. : :. :.: :: .. :::::...:.:: :: . .:...:. : ::.:. :.
CCDS42 GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPW
420 430 440 450 460 470
400 410 420 430 440
pF1KB4 NINFLRKLVQNGPEVHPGANFIQQRHTQMKRF--LKYGNREKMAQEL----------KYG
:.. ::. : :::.:::::... .. . . . . .:: .:..: .
CCDS42 NVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGT
480 490 500 510 520 530
450 460 470 480 490 500
pF1KB4 DIVERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPH-RTFRFNECVCTPYNADFDGDEMN
:: ::. .::..:.::::.::. ::.:: ::. :. ...:.. : :::::::::::
CCDS42 KIVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMN
540 550 560 570 580 590
510 520 530 540 550 560
pF1KB4 LHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQ
:.::.: ..::: :: : . ..:..:.:: . ::: .... .: . :: : . .
CCDS42 AHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYME
600 610 620 630 640 650
570 580 590 600 610 620
pF1KB4 IIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILR---PSDDNPVRANLRTK--G
.. :. :. .:.: :.:::: ::::::. :..: : : :. . ..: :
CCDS42 LVYRGLT--DKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITG
660 670 680 690 700 710
630 640 650 660 670
pF1KB4 KQYC--------GKGED-LCANDSYVTIQNSELMSGSMDKGTLGSGSKNNIFYILLRDWG
: . : . : .: .: : :...::. : .::. :: : .. . . .:
CCDS42 KAWVKETPRSVPGFNPDSMC--ESQVIIREGELLCGVLDKAHYGS-SAYGLVHCCYEIYG
720 730 740 750 760 770
680 690 700 710 720
pF1KB4 QNEAADAMSRLARLAPVYLS-NRGFSIGIGD--VTPGQGLLKAKY--ELLNAGYKKCDEY
. .. ... :::: .::. :::..:. : : : . . . : . : .
CCDS42 GETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAA
780 790 800 810 820 830
730 740 750 760 770
pF1KB4 I---EALN----TGKLQQQPGCTAEETLEALILK---ELSVIRDHAGSACL-----RELD
. :: . :: :. .. .. . :: :.. .. ..::. :..
CCDS42 LNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFP
840 850 860 870 880 890
780 790 800 810 820 830
pF1KB4 KSNSPLTMALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKG
. :: :. :.::: .: :. .:: . : : : ..::: :: . : : :
CCDS42 E-NSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGG
900 910 920 930 940
840 850 860 870 880 890
pF1KB4 FVANSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRS
::.. : .:. : ::::: ::::::::::::::...::.:: ..: :: : :::::::.
CCDS42 FVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRD
950 960 970 980 990 1000
900 910 920 930 940
pF1KB4 STGDIIQFIYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCP--------SEP--ALSK
: :...::.:: :::: . .: .: . .: .... ..: :: .
CCDS42 SDGSVVQFLYGEDGLDIPKTQFL-QPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHH
1010 1020 1030 1040 1050 1060
950 960 970 980
pF1KB4 NELILTTES-----IMKKSEFLCCQDSFLQEIKKFIK-----------GVSEKIK-----
. : .: ..... :: ... .:: : .: :..: ..
CCDS42 FRAIKKWQSKHPNTLLRRGAFLSYSQK-IQEAVKALKLESENRNGRSPGTQEMLRMWYEL
1070 1080 1090 1100 1110 1120
990 1000 1010
pF1KB4 --KTRDKYGINDNGTTEPRV------LY----------QLDRITP---TQVEKFLETCR-
..: :: . . .: . .: ..: . .:.:: : .
CCDS42 DEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSEL
1130 1140 1150 1160 1170 1180
1020 1030 1040 1050 1060
pF1KB4 --D--------KYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPR
: :..:. ::: ::: : :::::::.:::::.:::::: . ::.:::.::
CCDS42 SLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPR
1190 1200 1210 1220 1230 1240
1070 1080 1090 1100 1110 1120
pF1KB4 IKEIIN-ASKAISTPIITAQ-LDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCF
..::. :: :.::.... :. .. .: .. .. :::. . :.
CCDS42 LREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEE
1250 1260 1270 1280 1290 1300
1130 1140 1150 1160 1170 1180
pF1KB4 ILVKLSLERIRLLRLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYY
CCDS42 KQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNV
1310 1320 1330 1340 1350 1360
1390 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:53:40 2016 done: Wed Nov 2 22:53:41 2016
Total Scan time: 4.070 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]