Result of FASTA (omim) for
pFN21AA0148
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0148, 681 aa
1>>>pF1KA0148 681 - 681 aa - 681 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0678+/-0.000513; mu= 0.9740+/- 0.032
mean_var=238.2631+/-49.927, 0's: 0 Z-trim(115.9): 173 B-trim: 352 in 2/48
Lambda= 0.083089
statistics sampled from 26509 (26724) to 26509 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.313), width: 16
Scan time: 8.930
The best scores are: opt bits E(85289)
NP_001128685 (OMIM: 608564) ARF GTPase-activating ( 681) 4522 556.2 1.5e-157
NP_055591 (OMIM: 608564) ARF GTPase-activating pro ( 679) 4488 552.1 2.5e-156
XP_006719772 (OMIM: 608564) PREDICTED: ARF GTPase- ( 709) 3301 409.8 1.7e-113
NP_001317082 (OMIM: 608564) ARF GTPase-activating ( 708) 3300 409.7 1.9e-113
XP_006719775 (OMIM: 608564) PREDICTED: ARF GTPase- ( 596) 2759 344.8 5.5e-94
NP_476511 (OMIM: 608564) ARF GTPase-activating pro ( 631) 2754 344.2 8.8e-94
NP_001317083 (OMIM: 608564) ARF GTPase-activating ( 421) 2746 343.1 1.3e-93
XP_006719776 (OMIM: 608564) PREDICTED: ARF GTPase- ( 456) 2744 342.9 1.6e-93
NP_631940 (OMIM: 608564) ARF GTPase-activating pro ( 471) 2744 342.9 1.6e-93
XP_016875750 (OMIM: 608564) PREDICTED: ARF GTPase- ( 470) 2743 342.8 1.7e-93
XP_006719771 (OMIM: 608564) PREDICTED: ARF GTPase- ( 714) 2746 343.3 1.9e-93
XP_016875747 (OMIM: 608564) PREDICTED: ARF GTPase- ( 713) 2745 343.2 2e-93
XP_016875749 (OMIM: 608564) PREDICTED: ARF GTPase- ( 664) 2744 343.0 2.1e-93
XP_016875748 (OMIM: 608564) PREDICTED: ARF GTPase- ( 694) 2744 343.1 2.2e-93
NP_001128686 (OMIM: 608564) ARF GTPase-activating ( 729) 2744 343.1 2.2e-93
XP_006719770 (OMIM: 608564) PREDICTED: ARF GTPase- ( 744) 2744 343.1 2.3e-93
NP_476510 (OMIM: 608564) ARF GTPase-activating pro ( 759) 2744 343.1 2.3e-93
XP_005254054 (OMIM: 608564) PREDICTED: ARF GTPase- ( 758) 2743 343.0 2.5e-93
NP_001078923 (OMIM: 608434) ARF GTPase-activating ( 770) 2238 282.4 4.2e-75
XP_011522986 (OMIM: 608434) PREDICTED: ARF GTPase- ( 777) 2238 282.4 4.3e-75
NP_054749 (OMIM: 608434) ARF GTPase-activating pro ( 761) 2185 276.1 3.4e-73
XP_011522987 (OMIM: 608434) PREDICTED: ARF GTPase- ( 768) 2185 276.1 3.5e-73
XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462) 333 53.9 1.6e-06
XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP wit ( 527) 333 53.9 1.8e-06
XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP wit ( 565) 333 54.0 1.9e-06
NP_001268229 (OMIM: 616813) arf-GAP with GTPase, A ( 580) 333 54.0 1.9e-06
XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP wit ( 580) 333 54.0 1.9e-06
XP_016867221 (OMIM: 616813) PREDICTED: arf-GAP wit ( 630) 333 54.0 2e-06
XP_011514082 (OMIM: 616813) PREDICTED: arf-GAP wit ( 683) 333 54.0 2.1e-06
NP_114152 (OMIM: 616813) arf-GAP with GTPase, ANK ( 911) 333 54.1 2.7e-06
NP_055729 (OMIM: 608651) arf-GAP with GTPase, ANK ( 804) 317 52.2 9.1e-06
XP_005246116 (OMIM: 608651) PREDICTED: arf-GAP wit ( 808) 317 52.2 9.2e-06
NP_001032208 (OMIM: 608651) arf-GAP with GTPase, A ( 857) 317 52.2 9.6e-06
XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP wit ( 882) 317 52.2 9.8e-06
XP_006712297 (OMIM: 608651) PREDICTED: arf-GAP wit ( 886) 317 52.2 9.8e-06
XP_011508851 (OMIM: 608651) PREDICTED: arf-GAP wit (1073) 317 52.3 1.1e-05
XP_011508850 (OMIM: 608651) PREDICTED: arf-GAP wit (1098) 317 52.3 1.2e-05
XP_016858771 (OMIM: 608651) PREDICTED: arf-GAP wit (1106) 317 52.3 1.2e-05
XP_011508849 (OMIM: 608651) PREDICTED: arf-GAP wit (1126) 317 52.3 1.2e-05
XP_006712300 (OMIM: 608651) PREDICTED: arf-GAP wit (1147) 317 52.3 1.2e-05
XP_006712302 (OMIM: 608651) PREDICTED: arf-GAP wit (1151) 317 52.3 1.2e-05
NP_055585 (OMIM: 605476) arf-GAP with GTPase, ANK ( 836) 302 50.4 3.3e-05
XP_005268683 (OMIM: 605476) PREDICTED: arf-GAP wit ( 856) 302 50.4 3.3e-05
XP_005268682 (OMIM: 605476) PREDICTED: arf-GAP wit (1172) 302 50.5 4.2e-05
XP_016874261 (OMIM: 605476) PREDICTED: arf-GAP wit (1192) 302 50.5 4.3e-05
NP_001116244 (OMIM: 605476) arf-GAP with GTPase, A (1192) 302 50.5 4.3e-05
XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 265 45.9 0.00067
XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 265 45.9 0.00067
XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 265 45.9 0.00067
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 265 45.9 0.00067
>>NP_001128685 (OMIM: 608564) ARF GTPase-activating prot (681 aa)
initn: 4522 init1: 4522 opt: 4522 Z-score: 2949.7 bits: 556.2 E(85289): 1.5e-157
Smith-Waterman score: 4522; 100.0% identity (100.0% similar) in 681 aa overlap (1-681:1-681)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
610 620 630 640 650 660
670 680
pF1KA0 AYDIAKAAKQLVTITTKENNN
:::::::::::::::::::::
NP_001 AYDIAKAAKQLVTITTKENNN
670 680
>>NP_055591 (OMIM: 608564) ARF GTPase-activating protein (679 aa)
initn: 2747 init1: 2747 opt: 4488 Z-score: 2927.6 bits: 552.1 E(85289): 2.5e-156
Smith-Waterman score: 4488; 99.6% identity (99.6% similar) in 681 aa overlap (1-681:1-679)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_055 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
600 610 620 630 640 650
670 680
pF1KA0 AYDIAKAAKQLVTITTKENNN
:::::::::::::::::::::
NP_055 AYDIAKAAKQLVTITTKENNN
660 670
>>XP_006719772 (OMIM: 608564) PREDICTED: ARF GTPase-acti (709 aa)
initn: 4489 init1: 1764 opt: 3301 Z-score: 2158.4 bits: 409.8 E(85289): 1.7e-113
Smith-Waterman score: 4418; 95.4% identity (95.4% similar) in 711 aa overlap (1-681:1-709)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_006 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
420 430 440 450 460 470
490 500 510
pF1KA0 GEASRPEESRMRLQPFPAH------------------------------ASRLEKQNSTP
::::::::::::::::::: :::::::::::
XP_006 GEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDESARRASRLEKQNSTP
480 490 500 510 520 530
520 530 540 550 560 570
pF1KA0 ESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTE
540 550 560 570 580 590
580 590 600 610 620 630
pF1KA0 QITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAY
600 610 620 630 640 650
640 650 660 670 680
pF1KA0 RLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
660 670 680 690 700
>>NP_001317082 (OMIM: 608564) ARF GTPase-activating prot (708 aa)
initn: 4488 init1: 1763 opt: 3300 Z-score: 2157.8 bits: 409.7 E(85289): 1.9e-113
Smith-Waterman score: 4417; 95.4% identity (95.4% similar) in 711 aa overlap (1-681:1-708)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 HKNGQHFIIPQMAD---SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
420 430 440 450 460 470
490 500 510
pF1KA0 GEASRPEESRMRLQPFPAH------------------------------ASRLEKQNSTP
::::::::::::::::::: :::::::::::
NP_001 GEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDESARRASRLEKQNSTP
480 490 500 510 520 530
520 530 540 550 560 570
pF1KA0 ESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTE
540 550 560 570 580 590
580 590 600 610 620 630
pF1KA0 QITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAY
600 610 620 630 640 650
640 650 660 670 680
pF1KA0 RLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
660 670 680 690 700
>>XP_006719775 (OMIM: 608564) PREDICTED: ARF GTPase-acti (596 aa)
initn: 2949 init1: 1764 opt: 2759 Z-score: 1808.3 bits: 344.8 E(85289): 5.5e-94
Smith-Waterman score: 3764; 87.4% identity (87.4% similar) in 681 aa overlap (1-681:1-596)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_006 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK----
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
XP_006 ------------------------------------------------------------
490 500 510 520 530 540
pF1KA0 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
:::::::::::::::::::::::::::::::::::::::::
XP_006 -------------------ASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
420 430 440 450
550 560 570 580 590 600
pF1KA0 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
520 530 540 550 560 570
670 680
pF1KA0 AYDIAKAAKQLVTITTKENNN
:::::::::::::::::::::
XP_006 AYDIAKAAKQLVTITTKENNN
580 590
>>NP_476511 (OMIM: 608564) ARF GTPase-activating protein (631 aa)
initn: 2949 init1: 1764 opt: 2754 Z-score: 1804.7 bits: 344.2 E(85289): 8.8e-94
Smith-Waterman score: 3851; 89.1% identity (90.9% similar) in 681 aa overlap (1-681:1-631)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_476 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK----
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
: .:.: .: :: :. ...: :
NP_476 -SLDSDLSDGPVT----VQ---EFMEVKNA---------------------------LVA
420 430
490 500 510 520 530 540
pF1KA0 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
.:: ..: . .:::::::::::::::::::::::::::::::::::::::::
NP_476 SEA--------KIQQL-MKASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
440 450 460 470 480 490
550 560 570 580 590 600
pF1KA0 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
500 510 520 530 540 550
610 620 630 640 650 660
pF1KA0 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
560 570 580 590 600 610
670 680
pF1KA0 AYDIAKAAKQLVTITTKENNN
:::::::::::::::::::::
NP_476 AYDIAKAAKQLVTITTKENNN
620 630
>>NP_001317083 (OMIM: 608564) ARF GTPase-activating prot (421 aa)
initn: 1764 init1: 1764 opt: 2746 Z-score: 1801.9 bits: 343.1 E(85289): 1.3e-93
Smith-Waterman score: 2746; 99.3% identity (99.3% similar) in 417 aa overlap (1-417:1-415)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLLGK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
NP_001 DAN
420
>>XP_006719776 (OMIM: 608564) PREDICTED: ARF GTPase-acti (456 aa)
initn: 1764 init1: 1764 opt: 2744 Z-score: 1800.1 bits: 342.9 E(85289): 1.6e-93
Smith-Waterman score: 2744; 97.7% identity (98.6% similar) in 426 aa overlap (1-426:1-422)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_006 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: .:
XP_006 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK--SL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
.:. :.
XP_006 DSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKLLGKDAN
420 430 440 450
>>NP_631940 (OMIM: 608564) ARF GTPase-activating protein (471 aa)
initn: 1764 init1: 1764 opt: 2744 Z-score: 1799.9 bits: 342.9 E(85289): 1.6e-93
Smith-Waterman score: 2744; 97.7% identity (98.6% similar) in 426 aa overlap (1-426:1-422)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_631 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: .:
NP_631 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK--SL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
.:. :.
NP_631 DSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLLGKDAN
420 430 440 450 460 470
>>XP_016875750 (OMIM: 608564) PREDICTED: ARF GTPase-acti (470 aa)
initn: 1760 init1: 1760 opt: 2743 Z-score: 1799.3 bits: 342.8 E(85289): 1.7e-93
Smith-Waterman score: 2743; 97.7% identity (98.6% similar) in 426 aa overlap (1-426:1-421)
10 20 30 40 50 60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 HKNGQHFIIPQMAD---SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: .:
XP_016 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK--SL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
.:. :.
XP_016 DSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLLGKDAN
420 430 440 450 460 470
681 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:15:43 2016 done: Wed Nov 2 18:15:44 2016
Total Scan time: 8.930 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]