Gene/Protein Characteristic Table for FHC00001

Species
human

Product ID
FHC00001

Corresponding
Flexi Clone PID

ORF Sequence
DNA sequence (1014 bp)
Protein sequence (338 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB385264]

Gene
KIAA0001

Symbol
P2RY14
Alias : BPR105, GPR105, P2Y14

Description
purinergic receptor P2Y, G-protein coupled, 14

Original Clone ID
cp00460

Quality control data of this clone

Characterization of the cloned ORF

N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand

Features of the cloned ORF sequence

Length: 1014 bp
Restriction map A Restriction map B
Features of the protein sequence

Length: 338 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
NP_055694 4.2e-133 100.0 P2Y purinocepto...
Homo sapiens
BAA02791 4.3e-133 100.0 KIAA0001, parti...
Homo sapiens
AAH34989 8.7e-133 99.7 Purinergic rece...
Homo sapiens
XP_001145005 1.4e-132 99.1 P2Y purinocepto...
Pan troglodytes
XP_004037908 3.3e-132 99.1 P2Y purinocepto...
Gorilla gorilla...

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PR01655 PR00237 PR01655 PR00237 PR00237 PR01735 PR01655 PR01735 PR00237 PR01655 PR01735 PR00237 PR01655 PR01735 PR01655 PR00237 PR01655 PR00237 PF00001 PS50262

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR005466 3 23 PR01655 UDP-glucose receptor
IPR000276 24 48 PR00237 Rhodopsin-like GPCR superfamily
IPR005466 45 57 PR01655 UDP-glucose receptor
IPR000276 56 77 PR00237 Rhodopsin-like GPCR superfamily
IPR000276 101 123 PR00237 Rhodopsin-like GPCR superfamily
IPR008109 113 124 PR01735 P2Y13 purinoceptor
IPR005466 121 139 PR01655 UDP-glucose receptor
IPR008109 137 146 PR01735 P2Y13 purinoceptor
IPR000276 137 158 PR00237 Rhodopsin-like GPCR superfamily
IPR005466 160 179 PR01655 UDP-glucose receptor
IPR008109 161 176 PR01735 P2Y13 purinoceptor
IPR000276 187 210 PR00237 Rhodopsin-like GPCR superfamily
IPR005466 210 223 PR01655 UDP-glucose receptor
IPR008109 211 224 PR01735 P2Y13 purinoceptor
IPR005466 224 237 PR01655 UDP-glucose receptor
IPR000276 231 255 PR00237 Rhodopsin-like GPCR superfamily
IPR005466 262 279 PR01655 UDP-glucose receptor
IPR000276 277 303 PR00237 Rhodopsin-like GPCR superfamily
HMMPfam IPR000276 39 295 PF00001 Rhodopsin-like GPCR superfamily
ProfileScan IPR000276 39 295 PS50262 Rhodopsin-like GPCR superfamily

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 20 ITQQIIPVLYCMVFIAGILLNGV 42 PRIMARY 23
2 57 IIYLKNIVIADFVMSLTFPFKIL 79 PRIMARY 23
3 89 LNVFVCRVSAVLFYVNMYVSIVF 111 PRIMARY 23
4 140 LLSVIVWMLMLLLAVPNIILTNQ 162 PRIMARY 23
5 187 SNYIFVAIFWIVFLLLIVFYTAI 209 PRIMARY 23
6 232 SRNIFSIVFVFFVCFVPYHIARI 254 PRIMARY 23
7 278 EFTLLLSAANVCLDPIIYFFLCQ 300 SECONDARY 23

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_001074924 338 610116 100.0 100.0
NP_055694 338 610116 100.0 100.0
NP_795713 333 606380 78.6 90.5
NP_076403 333 606380 78.6 90.5
NP_795345 342 600515,609821 77.5 93.2
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