Gene/Protein Characteristic Table for pF1KSDA0111

Species
human

Product ID
FXC00412

Corresponding
HaloTag Clone PID

ORF Sequence
DNA sequence (1233 bp)
Protein sequence (411 aa)

Linker Type
Flexi_RBS type
The extra Tyr-Val-Val codons are attached to the 3'-end of the ORF, because ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB383751]

Gene

Symbol
EIF4A3
Alias : DDX48, NMP265, NUK34, eIF4AIII

Description
eukaryotic translation initiation factor 4A, isoform 3

Original Clone ID

Features of the cloned ORF sequence

Length: 1233 bp
Restriction map A Restriction map B
Genomic Structure
Features of the protein sequence

Length: 411 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
P38919 1.9e-168 100.0 Eukaryotic init...
Homo sapiens
AAX29071 1.9e-168 100.0 DEAD box polype...
synthetic construct
2HYI 1.9e-168 100.0 5'-R(*UP*UP*UP*...
Homo sapiens
Q2NL22 4.1e-168 99.7 Eukaryotic init...
Bos taurus
2J0Q 5.6e-168 100.0 ATP-DEPENDENT R...
Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PF00270 PF00271 SM00487 SM00490 PS51195 PS51192 PS51194 PS00039

Result of InterProScan

Search method interpro_ID From To Entry Definition
HMMPfam IPR011545 62 228 PF00270 DNA/RNA helicase
IPR001650 296 372 PF00271 DNA/RNA helicase
HMMSmart IPR014001 57 254 SM00487 DEAD-like helicases
IPR001650 291 372 SM00490 DNA/RNA helicase
ProfileScan IPR014014 38 66 PS51195 RNA helicase
IPR014021 69 239 PS51192 Helicase
IPR001650 250 411 PS51194 DNA/RNA helicase
ScanRegExp IPR000629 185 193 PS00039 RNA helicase

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_055555 411 608546 100.0 100.0
NP_001958 407 601102 89.6 91.7
NP_001407 406 602641 86.7 98.5
NP_004388 483 600326 71.7 98.3
NP_037396 483 607663 72.0 90.5
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