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SpecieshumanProduct IDFXC16507Cloning SiteSgfI-PmeIGenBank AccessionGeneKIEE1399SymbolSHANK2
Alias : AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3DescriptionSH3 and multiple ankyrin repeat domains 2, transcript variant 1Original Clone IDcs03195NoteWe obtained this clone using the E.coli strain JM109 at 25 deg C.
Length: 5547 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 1849 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS76448.1 3.4e-215 100.0 SHANK2 CCDS12799.1 6.6e-46 41.8 SHANK1
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR011511 531 583 PF07653 Variant SH3 IPR001478 627 716 PF00595 PDZ/DHR/GLGF IPR021129 1785 1846 PF00536 Sterile alpha motif HMMSmart IPR002110 196 226 SM00248 Ankyrin repeat IPR002110 230 259 SM00248 Ankyrin repeat IPR002110 263 293 SM00248 Ankyrin repeat IPR002110 297 326 SM00248 Ankyrin repeat IPR002110 330 359 SM00248 Ankyrin repeat IPR002110 363 391 SM00248 Ankyrin repeat IPR001452 529 584 SM00326 Src homology-3 domain IPR001478 635 720 SM00228 PDZ/DHR/GLGF IPR001660 1783 1849 SM00454 Sterile alpha motif domain ProfileScan IPR020683 182 383 PS50297 Ankyrin repeat-containing domain IPR002110 196 229 PS50088 Ankyrin repeat IPR002110 230 262 PS50088 Ankyrin repeat IPR002110 297 329 PS50088 Ankyrin repeat IPR002110 330 362 PS50088 Ankyrin repeat IPR001452 526 585 PS50002 Src homology-3 domain IPR001478 626 720 PS50106 PDZ/DHR/GLGF IPR001660 1786 1849 PS50105 Sterile alpha motif domain
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) XP_016872876 1849 603290,613436 100.0 100.0 XP_016872877 1849 603290,613436 100.0 100.0 NP_036441 1849 603290,613436 100.0 100.0 XP_016872878 1840 603290,613436 99.5 100.0 NP_277052 1731 606230,606232,613950 45.9 96.9 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KE1399 Download>KIEE1399 5547 bp ATGCCGCGCAGCCCAACATCCAGCGAGGACGAGATGGCCCAGAGCTTCTCCGACTACTCC GTGGGGTCGGAGTCAGACAGCTCCAAAGAAGAGACCATCTATGACACGATCCGGGCCACT GCGGAGAAGCCGGGCGGTGCCAGGACGGAGGAGAGCCAGGGCAACACGCTGGTGATCCGC GTGGTCATCCATGACCTGCAGCAGACGAAATGCATTCGATTTAACCCGGATGCCACAGTG TGGGTTGCAAAGCAGCGGATCCTGTGTACATTAACCCAGAGTTTGAAAGATGTCCTGAAC TACGGCCTGTTCCAGCCGGCCAGCAATGGGCGTGACGGCAAGTTCCTGGATGAGGAGCGG CTCCTGCGCGAGTACCCACAGCCCGTGGGTGAGGGCGTTCCTTCCCTGGAGTTTCGATAC AAGAAGCGGGTGTATAAACAAGCCAGTCTCGATGAGAAACAGTTGGCCAAGCTCCACACG AAGACCAATCTGAAGAAATGCATGGATCACATTCAGCATCGCTTGGTGGAGAAGATCACC AAGATGCTGGACCGAGGCCTGGATCCCAATTTCCACGACCCGGAGACCGGAGAGACCCCC CTGACCTTAGCCGCTCAGCTGGACGACTCTGTGGAGGTCATCAAAGCTCTCAAAAATGGT GGAGCTCACCTGGACTTCCGTGCCAAAGATGGGATGACCGCCCTACACAAAGCTGCCCGA GCGAGGAACCAAGTTGCCCTGAAGACCCTTTTAGAGCTTGGTGCATCCCCAGATTATAAA GACAGTTACGGCCTCACCCCGCTGTATCACACAGCCATCGTCGGAGGTGATCCCTACTGC TGCGAGCTTCTCCTGCACGAACACGCCACTGTGTGCTGCAAAGATGAGAACGGCTGGCAC GAGATCCACCAGGCCTGCAGGTACGGGCACGTGCAGCACCTGGAGCACCTGCTGTTCTAC GGGGCAGACATGAGTGCCCAGAATGCCTCGGGGAACACGGCCTTGCACATCTGCGCCCTC TACAACCAGGACAGCTGTGCAAGAGTGCTTCTGTTTCGAGGCGGAAATAAGGAGTTAAAA AACTACAACAGCCAGACTCCATTTCAGGTGGCCATAATAGCAGGCAACTTTGAGCTGGCA GAATACATCAAGAACCACAAGGAAACAGACATTGTGCCCTTCCGAGAGGCCCCGGCGTAC TCCAACCGCCGGCGGCGGCCCCCCAACACGCTGGCCGCCCCCCGGGTCCTGCTGCGCTCC AACAGTGACAACAACCTCAATGCCAGCGCTCCCGACTGGGCCGTCTGCTCCACGGCCACC TCGCACCGCAGCCTGTCACCCCAGCTGCTGCAGCAGATGCCCAGCAAGCCCGAGGGGGCC GCGAAGACCATTGGGAGCTACGTGCCCGGGCCCCGCAGCCGGTCCCCATCGCTCAACAGG CTGGGCGGCGCAGGCGAGGACGGCAAGAGGCCGCAGCCTCTCTGGCATGTCGGGTCGCCT TTTGCTCTTGGTGCCAACAAGGACTCACTCTCGGCCTTCGAGTACCCGGGGCCCAAGCGG AAGCTCTACAGTGCCGTGCCCGGGAGGCTCTTCGTCGCTGTCAAGCCATACCAACCCCAA GTGGACGGCGAGATCCCCCTTCACCGCGGTGACAGGGTCAAAGTTCTGAGCATCGGTGAA GGGGGCTTCTGGGAAGGCAGCGCCCGCGGCCACATCGGATGGTTTCCGGCGGAGTGCGTG GAGGAGGTCCAGTGTAAGCCCAGGGACAGCCAGGCAGAAACCCGCGCTGACCGCAGCAAG AAGCTTTTCAGGCACTACACCGTGGGCTCCTATGACAGCTTCGACACTTCCAGTGACTGC ATTATTGAGGAGAAGACGGTGGTCCTGCAGAAAAAAGACAATGAGGGCTTTGGATTCGTG CTTCGAGGGGCCAAAGCTGACACACCCATTGAAGAATTCACACCAACACCGGCTTTCCCA GCCCTACAGTACCTGGAGTCCGTGGATGAAGGTGGGGTGGCGTGGCAAGCCGGACTAAGG ACCGGGGACTTCTTGATTGAGGTTAACAATGAGAATGTTGTCAAAGTCGGCCACAGGCAG GTGGTGAACATGATCCGGCAGGGAGGGAATCACCTGGTCCTTAAGGTGGTCACGGTGACC AGGAATCTGGACCCCGACGACACCGCCAGGAAGAAAGCTCCCCCGCCTCCAAAGCGGGCA CCGACCACAGCCCTCACCCTGCGCTCCAAGTCCATGACCTCGGAGCTGGAGGAGCTCGTG GATAAAGCCTCGGTCCGGAAGAAGAAGGATAAACCCGAGGAGATAGTCCCGGCCTCCAAG CCCTCCCGCGCTGCTGAGAACATGGCTGTGGAACCGAGGGTGGCGACCATCAAGCAGCGG CCCAGCAGCCGGTGCTTCCCGGCGGGCTCAGACATGAACTCTGTGTACGAACGCCAAGGA ATCGCCGTGATGACGCCCACTGTTCCTGGGAGCCCAAAAGCCCCGTTTCTGGGCATCCCT CGAGGTACGATGCGAAGGCAGAAATCAATAGACAGCAGAATCTTTCTATCAGGAATAACA GAGGAAGAGCGGCAGTTTCTGGCTCCTCCAATGCTGAAGTTCACCAGAAGCCTGTCCATG CCGGACACCTCTGAGGACATCCCCCCTCCACCGCAGTCTGTGCCCCCGTCCCCACCACCA CCTTCCCCAACCACTTACAACTGCCCCAAGTCCCCAACTCCAAGAGTCTACGGGACGATT AAGCCTGCGTTCAATCAGAATTCTGCCGCCAAGGTGTCCCCCGCCACCAGGTCCGACACC GTGGCCACCATGATGAGGGAGAAGGGGATGTACTTCAGGAGAGAGCTGGACCGCTACTCC TTGGACTCTGAAGACCTCTACAGTCGGAATGCCGGCCCGCAAGCCAACTTCCGCAACAAG AGAGGCCAGATGCCAGAAAACCCATACTCAGAGGTGGGGAAGATCGCCAGCAAAGCCGTC TACGTCCCCGCCAAGCCCGCCAGGCGGAAGGGGATGCTGGTGAAGCAGTCCAACGTGGAG GACAGCCCCGAGAAGACGTGCTCCATCCCTATCCCGACCATCATCGTGAAGGAGCCGTCC ACCAGCAGCAGCGGCAAGAGCAGCCAGGGCAGCAGCATGGAGATCGACCCCCAGGCCCCG GAGCCACCGAGCCAGCTGCGGCCTGACGAAAGCCTGACCGTCAGCAGCCCCTTTGCCGCC GCCATCGCCGGAGCCGTCCGCGACCGTGAGAAGCGGCTGGAAGCCAGGAGGAACTCCCCG GCCTTCCTCTCCACAGACCTGGGGGATGAGGATGTGGGCCTGGGGCCACCCGCCCCCAGG ACGCGGCCCTCCATGTTCCCCGAGGAGGGGGATTTTGCTGACGAGGACAGCGCTGAGCAG CTGTCATCCCCCATGCCGAGTGCCACGCCCAGGGAGCCCGAAAACCATTTCGTGGGTGGC GCCGAGGCTAGTGCTCCGGGTGAGGCTGGGAGGCCGCTGAATTCCACGTCCAAAGCCCAG GGGCCCGAGAGCAGCCCAGCAGTGCCCTCCGCGAGCAGCGGCACAGCCGGCCCCGGGAAT TATGTCCACCCACTCACAGGGCGGCTGCTTGATCCCAGCTCCCCGCTGGCCCTGGCACTC TCCGCAAGGGACCGAGCCATGAAGGAGTCTCAACAGGGACCCAAAGGGGAGGCCCCCAAG GCCGACCTCAACAAACCTCTTTACATTGATACCAAAATGCGGCCCAGCCTGGATGCCGGC TTCCCTACGGTCACCAGGCAGAACACCCGGGGACCCCTGAGGCGGCAGGAGACGGAGAAC AAGTACGAGACCGACCTGGGCCGAGACCGGAAAGGCGATGACAAGAAGAACATGCTGATC GACATCATGGACACGTCCCAGCAGAAGTCGGCTGGCCTGCTGATGGTGCACACCGTGGAC GCCACTAAGCTGGACAACGCCCTGCAGGAAGAGGACGAGAAGGCAGAGGTGGAGATGAAG CCAGACAGCTCGCCGTCCGAGGTGCCAGAAGGTGTTTCCGAAACCGAAGGTGCTTTACAG ATCTCCGCTGCCCCCGAGCCCACCACCGTGCCCGGCAGAACCATCGTCGCGGTGGGCTCC ATGGAAGAGGCGGTGATTTTGCCATTCCGCATCCCTCCTCCCCCTCTGGCATCCGTGGAC TTGGATGAGGATTTTATTTTTACAGAGCCATTGCCTCCTCCCCTGGAATTTGCAAATAGT TTTGATATCCCCGATGACCGGGCAGCTTCTGTCCCGGCTCTCTCAGACTTAGTGAAGCAG AAGAAAAGCGACACCCCTCAGTCCCCTTCGTTGAACTCCAGCCAACCAACCAACTCTGCA GACAGCAAGAAGCCAGCCAGTCTTTCAAACTGTCTGCCTGCCTCATTCCTGCCACCCCCT GAAAGCTTTGACGCCGTCGCCGACTCTGGGATCGAGGAGGTGGACAGCCGGAGTAGCAGC GACCACCACCTCGAGACGACCAGCACTATCTCCACCGTGTCTAGCATCTCCACCCTGTCT TCCGAAGGTGGAGAGAATGTGGACACCTGCACAGTCTATGCAGATGGGCAAGCATTTATG GTTGACAAACCCCCAGTACCTCCTAAGCCAAAAATGAAGCCCATCATTCACAAAAGCAAT GCACTTTATCAAGACGCGCTCGTGGAAGAAGATGTAGATAGCTTTGTTATCCCCCCGCCC GCTCCCCCGCCCCCGCCGGGCAGTGCCCAGCCTGGGATGGCCAAGGTTCTCCAGCCAAGG ACCTCCAAGTTGTGGGGCGACGTCACAGAGATCAAAAGCCCGATTCTCTCAGGCCCAAAG GCAAACGTTATTAGTGAATTGAACTCTATCCTACAGCAAATGAACCGAGAGAAATTGGCA AAGCCGGGGGAAGGACTGGATTCACCAATGGGAGCCAAGTCCGCCAGCCTCGCTCCAAGA AGCCCGGAGATCATGAGCACCATCTCAGGTACACGGAGCACGACGGTCACCTTCACTGTT CGCCCCGGCACCTCCCAGCCCATCACCCTGCAGAGCCGGCCCCCCGACTATGAAAGCAGG ACCTCAGGAACAAGACGTGCCCCAAGCCCTGTGGTCTCGCCAACAGAGATGAACAAAGAG ACCCTGCCCGCCCCCCTGTCTGCTGCCACCGCCTCTCCTTCTCCCGCTCTCTCAGATGTC TTTAGCCTTCCAAGCCAGCCCCCTTCTGGGGATCTATTTGGCTTGAACCCAGCGGGACGC AGTAGGTCGCCATCCCCCTCGATACTGCAACAGCCAATCTCAAATAAGCCTTTTACAACT AAACCTGTCCACCTGTGGACTAAACCAGATGTGGCCGATTGGCTGGAAAGTCTAAACTTG GGTGAACATAAAGAGGCCTTCATGGACAATGAGATCGATGGCAGTCACTTACCAAACCTG CAGAAGGAGGACCTCATCGATCTTGGGGTAACTCGAGTCGGGCACAGAATGAACATAGAA AGGGCTTTGAAACAGCTGCTGGACAGA
Cloned ORF protein sequence for pF1KE1399 Download>KIEE1399 1849 aa MPRSPTSSEDEMAQSFSDYSVGSESDSSKEETIYDTIRATAEKPGGARTEESQGNTLVIR VVIHDLQQTKCIRFNPDATVWVAKQRILCTLTQSLKDVLNYGLFQPASNGRDGKFLDEER LLREYPQPVGEGVPSLEFRYKKRVYKQASLDEKQLAKLHTKTNLKKCMDHIQHRLVEKIT KMLDRGLDPNFHDPETGETPLTLAAQLDDSVEVIKALKNGGAHLDFRAKDGMTALHKAAR ARNQVALKTLLELGASPDYKDSYGLTPLYHTAIVGGDPYCCELLLHEHATVCCKDENGWH EIHQACRYGHVQHLEHLLFYGADMSAQNASGNTALHICALYNQDSCARVLLFRGGNKELK NYNSQTPFQVAIIAGNFELAEYIKNHKETDIVPFREAPAYSNRRRRPPNTLAAPRVLLRS NSDNNLNASAPDWAVCSTATSHRSLSPQLLQQMPSKPEGAAKTIGSYVPGPRSRSPSLNR LGGAGEDGKRPQPLWHVGSPFALGANKDSLSAFEYPGPKRKLYSAVPGRLFVAVKPYQPQ VDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVQCKPRDSQAETRADRSK KLFRHYTVGSYDSFDTSSDCIIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFP ALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVT RNLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELVDKASVRKKKDKPEEIVPASK PSRAAENMAVEPRVATIKQRPSSRCFPAGSDMNSVYERQGIAVMTPTVPGSPKAPFLGIP RGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPP PSPTTYNCPKSPTPRVYGTIKPAFNQNSAAKVSPATRSDTVATMMREKGMYFRRELDRYS LDSEDLYSRNAGPQANFRNKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVE DSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSMEIDPQAPEPPSQLRPDESLTVSSPFAA AIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRTRPSMFPEEGDFADEDSAEQ LSSPMPSATPREPENHFVGGAEASAPGEAGRPLNSTSKAQGPESSPAVPSASSGTAGPGN YVHPLTGRLLDPSSPLALALSARDRAMKESQQGPKGEAPKADLNKPLYIDTKMRPSLDAG FPTVTRQNTRGPLRRQETENKYETDLGRDRKGDDKKNMLIDIMDTSQQKSAGLLMVHTVD ATKLDNALQEEDEKAEVEMKPDSSPSEVPEGVSETEGALQISAAPEPTTVPGRTIVAVGS MEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRAASVPALSDLVKQ KKSDTPQSPSLNSSQPTNSADSKKPASLSNCLPASFLPPPESFDAVADSGIEEVDSRSSS DHHLETTSTISTVSSISTLSSEGGENVDTCTVYADGQAFMVDKPPVPPKPKMKPIIHKSN ALYQDALVEEDVDSFVIPPPAPPPPPGSAQPGMAKVLQPRTSKLWGDVTEIKSPILSGPK ANVISELNSILQQMNREKLAKPGEGLDSPMGAKSASLAPRSPEIMSTISGTRSTTVTFTV RPGTSQPITLQSRPPDYESRTSGTRRAPSPVVSPTEMNKETLPAPLSAATASPSPALSDV FSLPSQPPSGDLFGLNPAGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNL GEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR
Nucleotide Sequence (with vector) for pF1KE1399 Download>pF1KE1399 8660 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGCCGCGCAGC CCAACATCCAGCGAGGACGAGATGGCCCAGAGCTTCTCCGACTACTCCGTGGGGTCGGAG TCAGACAGCTCCAAAGAAGAGACCATCTATGACACGATCCGGGCCACTGCGGAGAAGCCG GGCGGTGCCAGGACGGAGGAGAGCCAGGGCAACACGCTGGTGATCCGCGTGGTCATCCAT GACCTGCAGCAGACGAAATGCATTCGATTTAACCCGGATGCCACAGTGTGGGTTGCAAAG CAGCGGATCCTGTGTACATTAACCCAGAGTTTGAAAGATGTCCTGAACTACGGCCTGTTC CAGCCGGCCAGCAATGGGCGTGACGGCAAGTTCCTGGATGAGGAGCGGCTCCTGCGCGAG TACCCACAGCCCGTGGGTGAGGGCGTTCCTTCCCTGGAGTTTCGATACAAGAAGCGGGTG TATAAACAAGCCAGTCTCGATGAGAAACAGTTGGCCAAGCTCCACACGAAGACCAATCTG AAGAAATGCATGGATCACATTCAGCATCGCTTGGTGGAGAAGATCACCAAGATGCTGGAC CGAGGCCTGGATCCCAATTTCCACGACCCGGAGACCGGAGAGACCCCCCTGACCTTAGCC GCTCAGCTGGACGACTCTGTGGAGGTCATCAAAGCTCTCAAAAATGGTGGAGCTCACCTG GACTTCCGTGCCAAAGATGGGATGACCGCCCTACACAAAGCTGCCCGAGCGAGGAACCAA GTTGCCCTGAAGACCCTTTTAGAGCTTGGTGCATCCCCAGATTATAAAGACAGTTACGGC CTCACCCCGCTGTATCACACAGCCATCGTCGGAGGTGATCCCTACTGCTGCGAGCTTCTC CTGCACGAACACGCCACTGTGTGCTGCAAAGATGAGAACGGCTGGCACGAGATCCACCAG GCCTGCAGGTACGGGCACGTGCAGCACCTGGAGCACCTGCTGTTCTACGGGGCAGACATG AGTGCCCAGAATGCCTCGGGGAACACGGCCTTGCACATCTGCGCCCTCTACAACCAGGAC AGCTGTGCAAGAGTGCTTCTGTTTCGAGGCGGAAATAAGGAGTTAAAAAACTACAACAGC CAGACTCCATTTCAGGTGGCCATAATAGCAGGCAACTTTGAGCTGGCAGAATACATCAAG AACCACAAGGAAACAGACATTGTGCCCTTCCGAGAGGCCCCGGCGTACTCCAACCGCCGG CGGCGGCCCCCCAACACGCTGGCCGCCCCCCGGGTCCTGCTGCGCTCCAACAGTGACAAC AACCTCAATGCCAGCGCTCCCGACTGGGCCGTCTGCTCCACGGCCACCTCGCACCGCAGC CTGTCACCCCAGCTGCTGCAGCAGATGCCCAGCAAGCCCGAGGGGGCCGCGAAGACCATT GGGAGCTACGTGCCCGGGCCCCGCAGCCGGTCCCCATCGCTCAACAGGCTGGGCGGCGCA GGCGAGGACGGCAAGAGGCCGCAGCCTCTCTGGCATGTCGGGTCGCCTTTTGCTCTTGGT GCCAACAAGGACTCACTCTCGGCCTTCGAGTACCCGGGGCCCAAGCGGAAGCTCTACAGT GCCGTGCCCGGGAGGCTCTTCGTCGCTGTCAAGCCATACCAACCCCAAGTGGACGGCGAG ATCCCCCTTCACCGCGGTGACAGGGTCAAAGTTCTGAGCATCGGTGAAGGGGGCTTCTGG GAAGGCAGCGCCCGCGGCCACATCGGATGGTTTCCGGCGGAGTGCGTGGAGGAGGTCCAG TGTAAGCCCAGGGACAGCCAGGCAGAAACCCGCGCTGACCGCAGCAAGAAGCTTTTCAGG CACTACACCGTGGGCTCCTATGACAGCTTCGACACTTCCAGTGACTGCATTATTGAGGAG AAGACGGTGGTCCTGCAGAAAAAAGACAATGAGGGCTTTGGATTCGTGCTTCGAGGGGCC AAAGCTGACACACCCATTGAAGAATTCACACCAACACCGGCTTTCCCAGCCCTACAGTAC CTGGAGTCCGTGGATGAAGGTGGGGTGGCGTGGCAAGCCGGACTAAGGACCGGGGACTTC TTGATTGAGGTTAACAATGAGAATGTTGTCAAAGTCGGCCACAGGCAGGTGGTGAACATG ATCCGGCAGGGAGGGAATCACCTGGTCCTTAAGGTGGTCACGGTGACCAGGAATCTGGAC CCCGACGACACCGCCAGGAAGAAAGCTCCCCCGCCTCCAAAGCGGGCACCGACCACAGCC CTCACCCTGCGCTCCAAGTCCATGACCTCGGAGCTGGAGGAGCTCGTGGATAAAGCCTCG GTCCGGAAGAAGAAGGATAAACCCGAGGAGATAGTCCCGGCCTCCAAGCCCTCCCGCGCT GCTGAGAACATGGCTGTGGAACCGAGGGTGGCGACCATCAAGCAGCGGCCCAGCAGCCGG TGCTTCCCGGCGGGCTCAGACATGAACTCTGTGTACGAACGCCAAGGAATCGCCGTGATG ACGCCCACTGTTCCTGGGAGCCCAAAAGCCCCGTTTCTGGGCATCCCTCGAGGTACGATG CGAAGGCAGAAATCAATAGACAGCAGAATCTTTCTATCAGGAATAACAGAGGAAGAGCGG CAGTTTCTGGCTCCTCCAATGCTGAAGTTCACCAGAAGCCTGTCCATGCCGGACACCTCT GAGGACATCCCCCCTCCACCGCAGTCTGTGCCCCCGTCCCCACCACCACCTTCCCCAACC ACTTACAACTGCCCCAAGTCCCCAACTCCAAGAGTCTACGGGACGATTAAGCCTGCGTTC AATCAGAATTCTGCCGCCAAGGTGTCCCCCGCCACCAGGTCCGACACCGTGGCCACCATG ATGAGGGAGAAGGGGATGTACTTCAGGAGAGAGCTGGACCGCTACTCCTTGGACTCTGAA GACCTCTACAGTCGGAATGCCGGCCCGCAAGCCAACTTCCGCAACAAGAGAGGCCAGATG CCAGAAAACCCATACTCAGAGGTGGGGAAGATCGCCAGCAAAGCCGTCTACGTCCCCGCC AAGCCCGCCAGGCGGAAGGGGATGCTGGTGAAGCAGTCCAACGTGGAGGACAGCCCCGAG AAGACGTGCTCCATCCCTATCCCGACCATCATCGTGAAGGAGCCGTCCACCAGCAGCAGC GGCAAGAGCAGCCAGGGCAGCAGCATGGAGATCGACCCCCAGGCCCCGGAGCCACCGAGC CAGCTGCGGCCTGACGAAAGCCTGACCGTCAGCAGCCCCTTTGCCGCCGCCATCGCCGGA GCCGTCCGCGACCGTGAGAAGCGGCTGGAAGCCAGGAGGAACTCCCCGGCCTTCCTCTCC ACAGACCTGGGGGATGAGGATGTGGGCCTGGGGCCACCCGCCCCCAGGACGCGGCCCTCC ATGTTCCCCGAGGAGGGGGATTTTGCTGACGAGGACAGCGCTGAGCAGCTGTCATCCCCC ATGCCGAGTGCCACGCCCAGGGAGCCCGAAAACCATTTCGTGGGTGGCGCCGAGGCTAGT GCTCCGGGTGAGGCTGGGAGGCCGCTGAATTCCACGTCCAAAGCCCAGGGGCCCGAGAGC AGCCCAGCAGTGCCCTCCGCGAGCAGCGGCACAGCCGGCCCCGGGAATTATGTCCACCCA CTCACAGGGCGGCTGCTTGATCCCAGCTCCCCGCTGGCCCTGGCACTCTCCGCAAGGGAC CGAGCCATGAAGGAGTCTCAACAGGGACCCAAAGGGGAGGCCCCCAAGGCCGACCTCAAC AAACCTCTTTACATTGATACCAAAATGCGGCCCAGCCTGGATGCCGGCTTCCCTACGGTC ACCAGGCAGAACACCCGGGGACCCCTGAGGCGGCAGGAGACGGAGAACAAGTACGAGACC GACCTGGGCCGAGACCGGAAAGGCGATGACAAGAAGAACATGCTGATCGACATCATGGAC ACGTCCCAGCAGAAGTCGGCTGGCCTGCTGATGGTGCACACCGTGGACGCCACTAAGCTG GACAACGCCCTGCAGGAAGAGGACGAGAAGGCAGAGGTGGAGATGAAGCCAGACAGCTCG CCGTCCGAGGTGCCAGAAGGTGTTTCCGAAACCGAAGGTGCTTTACAGATCTCCGCTGCC CCCGAGCCCACCACCGTGCCCGGCAGAACCATCGTCGCGGTGGGCTCCATGGAAGAGGCG GTGATTTTGCCATTCCGCATCCCTCCTCCCCCTCTGGCATCCGTGGACTTGGATGAGGAT TTTATTTTTACAGAGCCATTGCCTCCTCCCCTGGAATTTGCAAATAGTTTTGATATCCCC GATGACCGGGCAGCTTCTGTCCCGGCTCTCTCAGACTTAGTGAAGCAGAAGAAAAGCGAC ACCCCTCAGTCCCCTTCGTTGAACTCCAGCCAACCAACCAACTCTGCAGACAGCAAGAAG CCAGCCAGTCTTTCAAACTGTCTGCCTGCCTCATTCCTGCCACCCCCTGAAAGCTTTGAC GCCGTCGCCGACTCTGGGATCGAGGAGGTGGACAGCCGGAGTAGCAGCGACCACCACCTC GAGACGACCAGCACTATCTCCACCGTGTCTAGCATCTCCACCCTGTCTTCCGAAGGTGGA GAGAATGTGGACACCTGCACAGTCTATGCAGATGGGCAAGCATTTATGGTTGACAAACCC CCAGTACCTCCTAAGCCAAAAATGAAGCCCATCATTCACAAAAGCAATGCACTTTATCAA GACGCGCTCGTGGAAGAAGATGTAGATAGCTTTGTTATCCCCCCGCCCGCTCCCCCGCCC CCGCCGGGCAGTGCCCAGCCTGGGATGGCCAAGGTTCTCCAGCCAAGGACCTCCAAGTTG TGGGGCGACGTCACAGAGATCAAAAGCCCGATTCTCTCAGGCCCAAAGGCAAACGTTATT AGTGAATTGAACTCTATCCTACAGCAAATGAACCGAGAGAAATTGGCAAAGCCGGGGGAA GGACTGGATTCACCAATGGGAGCCAAGTCCGCCAGCCTCGCTCCAAGAAGCCCGGAGATC ATGAGCACCATCTCAGGTACACGGAGCACGACGGTCACCTTCACTGTTCGCCCCGGCACC TCCCAGCCCATCACCCTGCAGAGCCGGCCCCCCGACTATGAAAGCAGGACCTCAGGAACA AGACGTGCCCCAAGCCCTGTGGTCTCGCCAACAGAGATGAACAAAGAGACCCTGCCCGCC CCCCTGTCTGCTGCCACCGCCTCTCCTTCTCCCGCTCTCTCAGATGTCTTTAGCCTTCCA AGCCAGCCCCCTTCTGGGGATCTATTTGGCTTGAACCCAGCGGGACGCAGTAGGTCGCCA TCCCCCTCGATACTGCAACAGCCAATCTCAAATAAGCCTTTTACAACTAAACCTGTCCAC CTGTGGACTAAACCAGATGTGGCCGATTGGCTGGAAAGTCTAAACTTGGGTGAACATAAA GAGGCCTTCATGGACAATGAGATCGATGGCAGTCACTTACCAAACCTGCAGAAGGAGGAC CTCATCGATCTTGGGGTAACTCGAGTCGGGCACAGAATGAACATAGAAAGGGCTTTGAAA CAGCTGCTGGACAGAGTTTAAACGAATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCG ACCTGCAGGCATGCAAGCTGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGC TGCTGCCACCGCTGAGCAATAACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAG GGGTTTTTTGCTGAAAGGAGGAACTATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCA GTCTAGCTATCGCCATGTAAGCCCACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTT TTCCCTTGTCCAGATAGCCCAGTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGG ACTGGCTTTCTACGTGTTCCGCTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCA GCGTGAGCTTCAAAAGAATTGCCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGC AAAGTAAACTGGATGGCTTTCTTGCCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCT GATCAAGAGACAGGATGACGGTCGTTTCGCATGCTTGAACAAGATGGATTGCACGCAGGT TCTCCGGCCGCTTGGGTGGAGAGGCTATTCGGCTATGACTGGGCACAACAGACAATCGGC TGCTCTGATGCCGCCGTGTTCCGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAG ACCGACCTGTCCGGTGCCCTGAATGAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTG GCCACGACGGGCGTTCCTTGCGCAGCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGAC TGGCTGCTATTGGGCGAAGTGCCGGGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCC GAGAAAGTATCCATCATGGCTGATGCAATGCGGCGGCTGCATACGCTTGATCCGGCTACC TGCCCATTCGACCACCAAGCGAAACATCGCATCGAGCGAGCACGCACTCGGATGGAAGCC GGTCTTGTCGATCAGGATGATCTGGACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTG TTCGCCAGGCTCAAGGCGCGTATGCCGGATGGTGAGGATCTCGTCGTGACTCATGGCGAT GCCTGCTTGCCGAATATCATGGTGGAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGC CGGCTGGGTGTGGCGGACCGCTATCAGGACATAGCGTTGGCTACCCGTGATATTGCTGAA GAGCTTGGCGGCGAATGGGCTGACCGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGAT TCGCAGCGCATCGCCTTCTATCGCCTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGT TCGAAATGACCGACCAAGCGACGCCCAACCGGTATCAGCTCACTCAAAGGCGGTAATACG GTTATCCACAGAATCAGGGGATAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGCAAAA GGCCAGGAACCGTAAAAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGA CGAGCATCACAAAAATCGACGCTCAAGTCAGAGGTGGCGAAACCCGACAGGACTATAAAG ATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCT TACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACG CTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACC CCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGT AAGACACGACTTATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTA TGTAGGCGGTGCTACAGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGGAC AGTATTTGGTATCTGCGCTCTGCTGAAGCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTC TTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGAT TACGCGCAGAAAAAAAGGATTTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGC TCAGTGGAACGAAAACTCACGTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATCTT CACCTAGATCCTTTTATAGTCCGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGG GATGGTGAAACCATGAAAAATGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGT ACCCTCTGGTTGCATAGGTATTCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTT TTTCGGGTGGTTTGTTGCCATTTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTT TAGCGGTGCGTACAATTAAGGGATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCA TCGAGATAAACCGCAGTACTCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTT CAGCCTGATACAGATTAAATCAGAACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGG CGGCAGTAGCGCGGTGGTCCCACCTGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAG CGCCGATGGTAGTGTGGGGTCTCCCCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAA AACGAAAGGCTCAGTCGAAAGACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACG CTCTCCTGAGTAGGACAAATCCGCCGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCG GAGGGTGGCGGGCAGGACGCCCGCCATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCA TCCTGACGGATGGCCTTTTTGCGTTTCTACAAACTCTTTTGTTTATTTTTCTAAATACAT TCAAATATGTATCCGCTCAT
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