Gene/Protein Characteristic Table for FXC03046

Species
human

Product ID
FXC03046

Corresponding
HaloTag Clone PID

ORF Sequence
DNA sequence (1212 bp)
Protein sequence (404 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB464542]

Gene
KIBB8823

Symbol
GPR182
Alias : 7TMR, ADMR, AM-R, AMR, G10D, gamrh, hrhAMR

Description
G protein-coupled receptor 182

Original Clone ID
cp00858

Features of the cloned ORF sequence

Length: 1212 bp
Restriction map A Restriction map B
Genomic Structure
Features of the protein sequence

Length: 404 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
NP_009195 3.1e-169 100.0 G-protein coupl...
Homo sapiens
ABM87805 6.6e-169 99.8 adrenomedullin ...
synthetic construct
CAC79687 6.6e-169 99.8 G-protein coupl...
Homo sapiens
XP_003824949 4.1e-167 99.3 G-protein coupl...
Pan paniscus
XP_004053450 1.1e-166 98.5 G-protein coupl...
Gorilla gorilla...

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PR00643 PR00643 PR00643 PR00237 PR00643 PR00237 PR00237 PR00643 PR00237 PR00643 PR00237 PR00643 PR00237 PR00643 PR00237 PR00643 PF00001 PS50262 PS00237

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR001350 7 26 PR00643 G10D orphan receptor
IPR001350 26 42 PR00643 G10D orphan receptor
IPR001350 42 57 PR00643 G10D orphan receptor
IPR000276 55 79 PR00237 Rhodopsin-like GPCR superfamily
IPR001350 76 87 PR00643 G10D orphan receptor
IPR000276 88 109 PR00237 Rhodopsin-like GPCR superfamily
IPR000276 133 155 PR00237 Rhodopsin-like GPCR superfamily
IPR001350 154 171 PR00643 G10D orphan receptor
IPR000276 169 190 PR00237 Rhodopsin-like GPCR superfamily
IPR001350 196 214 PR00643 G10D orphan receptor
IPR000276 219 242 PR00237 Rhodopsin-like GPCR superfamily
IPR001350 243 257 PR00643 G10D orphan receptor
IPR000276 256 280 PR00237 Rhodopsin-like GPCR superfamily
IPR001350 291 308 PR00643 G10D orphan receptor
IPR000276 302 328 PR00237 Rhodopsin-like GPCR superfamily
IPR001350 331 350 PR00643 G10D orphan receptor
HMMPfam IPR000276 70 320 PF00001 Rhodopsin-like GPCR superfamily
ProfileScan IPR000276 70 320 PS50262 Rhodopsin-like GPCR superfamily
ScanRegExp IPR000276 139 155 PS00237 Rhodopsin-like GPCR superfamily

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 54 VVLFALYLAMFVVGLVENLLVIC 76 PRIMARY 23
2 88 MNLYILNMAIADLGIVLSLPVWM 110 PRIMARY 23
3 133 YFVNMYSSIFFLVCLSVDRYVTL 155 SECONDARY 23
4 172 AMCAGIWVLSAIIPLPEVVHIQL 194 PRIMARY 23
5 199 EPMCLFMAPFETYSTWALAVALS 221 SECONDARY 23
6 223 TILGFLLPFPLITVFNVLTACR 244 PRIMARY 22
7 259 LLCAYVAVFVMCWLPYHVTLLLL 281 PRIMARY 23
8 297 LLYFFYDVIDCFSMLHCVINPIL 319 PRIMARY 23

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_009195 404 605307 100.0 100.0
NP_005192 355 601834 62.0 80.9
NP_112477 369 604738 62.1 80.4
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