hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-19163080/chunk_1/iprscan-20080502-19163080.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA2017 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF03028.6.fs Dynein heavy chain 1003.2 2.1e-302 1 PF03028.6.ls Dynein heavy chain 1005.0 2.4e-299 1 PF08393.3.fs Dynein heavy chain, N-terminal region 2 405.0 1.8e-120 1 PF08393.3.ls Dynein heavy chain, N-terminal region 2 168.0 2.3e-47 1 PF07728.4.fs ATPase family associated with various ce 91.7 1.5e-26 5 PF07728.4.ls ATPase family associated with various ce 72.7 1.1e-18 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF08393.3.ls 1/1 1 244 [. 1 427 [] 168.0 2.3e-47 PF08393.3.fs 1/1 3 244 .. 181 427 .] 405.0 1.8e-120 PF07728.4.fs 2/5 688 833 .. 1 184 [] 40.7 1.2e-11 PF07728.4.ls 1/2 688 833 .. 1 184 [] 42.5 1.3e-09 PF07728.4.ls 2/2 1030 1177 .. 1 184 [] 30.2 6.8e-06 PF03028.6.fs 1/1 2338 3049 .. 1 783 [] 1003.2 2.1e-302 PF03028.6.ls 1/1 2338 3049 .. 1 783 [] 1005.0 2.4e-299 Alignments of top-scoring domains: PF08393.3.ls: domain 1 of 1, from 1 to 244: score 168.0, E = 2.3e-47 *->peLkqleeElkllkqlWdlysevwesidewketpWsdlRdpekleee KIAA2017 - ----------------------------------------------- - ldkllkqlrkLpkevrqyeakeafeklkqkiknfkkslpllqeLknpamk KIAA2017 - -------------------------------------------------- - eRHWeqLmqilgvkdfdkknkldsesltLgdlldlnLilkyeeeikdIvd KIAA2017 - -------------------------------------------------- - qAqkElaiEkaLkeiketWsnveFelvpYkdtgrckllkGgwdelfekLe +++g ++l ++de+++ L+ KIAA2017 1 -----------------------------QERG--YILG-SVDEIIQSLD 18 DnqvlLqsMkaSpyykpFedeiseWekKLslldeileiWleVQrkWvYLE Dn +Lqs++ S+++ pF++++ +Wek+Lsl+ e++eiW+ VQrkW+YLE KIAA2017 19 DNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLE 68 gIFigSeDIrkQLPeEakRFdnIDkeflkiMkkvakdpnVldvcnipgll +IFig+ DIr+QLPeEak+FdnIDk f++iM ++ kdp + +c p++l KIAA2017 69 SIFIGG-DIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRL 117 eslLerlneqLekcQKaLneYLEtKRlaFPRFYFlSDdDLLEILGnskdP L++++e LekcQK+Ln+YL++KR+aFPRF+F+SDd+LL+ILG s+dP KIAA2017 118 SD-LQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILG-SSDP 165 trvQkHLkKlFdgIasLefdedgkd.ktIvgmvSkEGEeVpfsnpvsieg vQ H+ K++d+IasL+f+++++++k + +m+S EGE+ +f++ v++eg KIAA2017 166 LCVQEHMIKMYDNIASLRFNDGDSGeKLVSAMISAEGEVMEFRKIVRAEG 215 appVEeWLneLedeMkaTLkellreaveayr<-* +VE+W++++ +eM++T + +++ea++ y KIAA2017 216 --RVEDWMTAVLNEMRRTNRLITKEAIFRYC 244 PF08393.3.fs: domain 1 of 1, from 3 to 244: score 405.0, E = 1.8e-120 *->rckllkGgwdelfekLeDnqvlLqsMkaSpyykpFedeiseWekKLs r ++l ++de+++ L+Dn +Lqs++ S+++ pF++++ +Wek+Ls KIAA2017 3 RGYILG-SVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLS 48 lldeileiWleVQrkWvYLEgIFigSeDIrkQLPeEakRFdnIDkeflki l+ e++eiW+ VQrkW+YLE+IFig+ DIr+QLPeEak+FdnIDk f++i KIAA2017 49 LIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEAKKFDNIDKVFKRI 97 MkkvakdpnVldvcnipglleslLerlneqLekcQKaLneYLEtKRlaFP M ++ kdp + +c p++l L++++e LekcQK+Ln+YL++KR+aFP KIAA2017 98 MGETLKDPVIKRCCEAPNRLSD-LQNVSEGLEKCQKSLNDYLDSKRNAFP 146 RFYFlSDdDLLEILGnskdPtrvQkHLkKlFdgIasLefdedgkd.ktIv RF+F+SDd+LL+ILG s+dP vQ H+ K++d+IasL+f+++++++k + KIAA2017 147 RFFFISDDELLSILG-SSDPLCVQEHMIKMYDNIASLRFNDGDSGeKLVS 195 gmvSkEGEeVpfsnpvsiegappVEeWLneLedeMkaTLkellreaveay +m+S EGE+ +f++ v++eg +VE+W++++ +eM++T + +++ea++ y KIAA2017 196 AMISAEGEVMEFRKIVRAEG--RVEDWMTAVLNEMRRTNRLITKEAIFRY 243 r<-* KIAA2017 244 C 244 PF07728.4.fs: domain 2 of 5, from 688 to 833: score 40.7, E = 1.2e-11 *->gvlLvGpPGtGKselaerlaealsgqggrplfyvqltrdtteedLlg + vGp+ GKs ++ l++a ++ g ++y+++++ + +L g KIAA2017 688 TTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYG 734 rrdiapllhGngttswvdgpLvrAaryaretegslpeghivvlDEinras ++d + t+ w+dg+L r + +++ ++ i+++++++ KIAA2017 735 ILD-------PTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVD--- 774 pevlnaLlslLderrlllpdggelvkvapydklaergreeldlwklgrli + + ++s++d++rll+ +ge++ +++++ KIAA2017 775 ALWVENMNSVMDDNRLLTLANGERI-------RLQAH------------- 804 hdfrliataNpldgprglnelsaALrrRFlfvtvdpp<-* l+++ ++l+ +s+A+++R+ +v+vdp KIAA2017 805 --CALLFEVGDLQ------YASPATVSRCGMVYVDPK 833 PF07728.4.ls: domain 1 of 2, from 688 to 833: score 42.5, E = 1.3e-09 *->gvlLvGpPGtGKselaerlaealsgqggrplfyvqltrdtteedLlg + vGp+ GKs ++ l++a ++ g ++y+++++ + +L g KIAA2017 688 TTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYG 734 rrdiapllhGngttswvdgpLvrAaryaretegslpeghivvlDEinras ++d + t+ w+dg+L r + +++ ++ i+++++++ KIAA2017 735 ILD-------PTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVD--- 774 pevlnaLlslLderrlllpdggelvkvapydklaergreeldlwklgrli + + ++s++d++rll+ +ge++ +++++ KIAA2017 775 ALWVENMNSVMDDNRLLTLANGERI-------RLQAH------------- 804 hdfrliataNpldgprglnelsaALrrRFlfvtvdpp<-* l+++ ++l+ +s+A+++R+ +v+vdp KIAA2017 805 --CALLFEVGDLQ------YASPATVSRCGMVYVDPK 833 PF07728.4.ls: domain 2 of 2, from 1030 to 1177: score 30.2, E = 6.8e-06 *->gvlLvGpPGtGKselaerlaealsgqggrplfyvqltrdtteedLlg +v++vG++Gt K+ ++ +++ ls + + +++v +++ tt+ d+ KIAA2017 1030 PVIFVGESGTSKTATTQNFLKNLSEE-TNIVLMVNFSSRTTSMDIQR 1075 rrdiapllhGngttswvdgpLvrAaryaretegslpeghivvlDEinras ++ ++ ++++ + + + v+ D+ n+ + KIAA2017 1076 NLE-------ANVEKRTKDTYGPPMG----------KRLLVFMDDMNMPR 1108 .pev.....lnaLlslLderrlllpdggelvkvapydklaergreeldlw +e ++++++ L lL+ ++l+ d+g+++ ++ KIAA2017 1109 vDEYgtqqpIALLKLLLEKGYLY--DRGKELNCKS--------------- 1141 klgrlihdfrliataNpldgprglnelsaALrrRFlfvtvdpp<-* i d +ia+++ ++ +g+ne+++ ++++F +v+ p KIAA2017 1142 -----IRDLGFIAAMGKAG--GGRNEVDPRFISLFSVFNVPFP 1177 PF03028.6.fs: domain 1 of 1, from 2338 to 3049: score 1003.2, E = 2.1e-302 *->lentypnpkvdwlsdqqWdsiarLselee..FrgLdddleknapdkr ++ +++p+ wlsdq+W++i+ Lse+++++F L+dd+e n+ KIAA2017 2338 EKSKRKKPC-AWLSDQGWEDIILLSEMFSdnFGQLPDDVENNQ--TV 2381 WkkwydseqPgEeeklPkeWkdeqklsidslkksaFqKLlllRalRPDRl W++wyd ++ E ++P +++ + ++FqKLl+lR++R DR+ KIAA2017 2382 WQEWYDLDSL-EQFPVPLGYDN---------NITPFQKLLILRCFRVDRV 2421 tyalrnFveekLpGekfvepdppldlskiyekeSspstPilFiLSPGaDP + a++++v ++ Gek+v+p p ++ i+e +S+p Pi+FiLSPG+DP KIAA2017 2422 YRAVTDYVTVTM-GEKYVQP-PMISFEAIFE-QSTPHSPIVFILSPGSDP 2468 skdvekLAkkmGFtfdnGkklhSiSLGQGQgpniAekaIetAaksGhWVl + d+ kLA+ G ++G++l+ +++GQGQ+ +A +++etA+ +G W + KIAA2017 2469 ATDLMKLAERSG---FGGNRLKFLAMGQGQEK-VALQLLETAVARGQWLM 2514 LQNiHLaasWLptLEKkLesltppegtHpdFRLFLTaEpaprPeehIfPi LQN+HL +WL++LEK Le++t+ +HpdFRL+LT+ p+ fPi KIAA2017 2515 LQNCHLLVKWLKDLEKSLERITK---PHPDFRLWLTTDPTKG-----FPI 2556 glLqnSiKiTNEPPtGlKANLlraysnDPIfdqeflemckkpaefkrllF g+Lq S+K+++EPP+GlK N++++y + ++ e+l++c++p +fk+l++ KIAA2017 2557 GILQKSLKVVTEPPNGLKLNMRATYFK---ISHEMLDQCPHP-AFKPLVY 2602 lLCfFHAVVqERRkFGPlGWNksYEFNesDLriSvdvldnyLeanakGRq +L+fFHAVVqERRkFG++GWN+ Y+FNesD+++++ l++yL++ + KIAA2017 2603 VLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQ--- 2649 NidpdkvPWeaLRYlfGeimYGGrItDdwDrRLLrtyLeefftpelfdgn ++++PW L+Yl+Ge+mYGGr D +DrR+L+ y +e+ +++fd++ KIAA2017 2650 -QRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTF 2698 adyeLapkidgdlgfavPpntdyeeYieyIeesLPsessPelfGLhpNAE +++ +++ + ++++P + + e+++e Ie+ LP +Pe+fGLhpNAE KIAA2017 2699 QPFHFFRN--KEVDYKIPVGDEKEKFVEAIEA-LPLANTPEVFGLHPNAE 2745 IgfltqeteklirtllelQpreaggeldggsgekvsrkkdssEEvvkqvl Ig++tq +++++ +llelQp + + +sg sr ++ + qv+ KIAA2017 2746 IGYYTQAARDMWAHLLELQPQTGE----SSSG--ISR-----DDYIGQVA 2784 rdileklpkklCqklFdkeelmlkrteeikdPlfvVlvQEiermNkLlke ++i k+p k Fd+++++++++++ +P+ vVl+QE+er+NkL+ KIAA2017 2785 KEIENKMP-----KVFDLDQVRKRLGTGL-SPTSVVLLQELERFNKLVVR 2828 irrSLkeLdlglkGeltmsndlEeliksLlngrVPaWDmWakksyPslkp +++SL+eL+++l Ge+ msn+l +++ sL++g +P W+++++ +lk+ KIAA2017 2829 MTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPN--IWRRLAPDTLKS 2876 LgsWvtDLlkRirQLqeWtedsGGAklglPkvvWLsGFFnPQsFLTAimQ Lg+W+ +l+R Q+ W ++ ++P+v WLsG+++P+s+LTA+ Q KIAA2017 2877 LGNWMVYFLRRFSQYMLWVTE------SEPSVMWLSGLHIPESYLTALVQ 2920 svARknkwPLDkLcLdteVtkkekeeqdskepPedGvyVhGLfLEGArWD +++Rkn+wPLD+ +L t Vtk+++ ++ ++ + +G++V+GL+LEGA WD KIAA2017 2921 ATCRKNGWPLDRSTLFTQVTKFQDADEVNER-AGQGCFVSGLYLEGADWD 2969 sktgllaeskpKeLfspmPViwlkavpasdkqetkdvyecPVYktkaRgg +++g l++skpK+L+ +P++ + +++a +++ +++++ PVY t+ R++ KIAA2017 2970 IEKGCLIKSKPKVLVVDLPILKIIPIEA-HRLKLQNTFRTPVYTTSMRRN 3018 vLSTTGHStnyvftfnLktkedtpaskWilaGVALllq<-* +++ +++vf+++L t + s+W+l+GV+L l+ KIAA2017 3019 AMG-----VGLVFEADLFTTR--HISHWVLQGVCLTLN 3049 PF03028.6.ls: domain 1 of 1, from 2338 to 3049: score 1005.0, E = 2.4e-299 *->lentypnpkvdwlsdqqWdsiarLselee..FrgLdddleknapdkr ++ +++p+ wlsdq+W++i+ Lse+++++F L+dd+e n+ KIAA2017 2338 EKSKRKKPC-AWLSDQGWEDIILLSEMFSdnFGQLPDDVENNQ--TV 2381 WkkwydseqPgEeeklPkeWkdeqklsidslkksaFqKLlllRalRPDRl W++wyd ++ E ++P +++ + ++FqKLl+lR++R DR+ KIAA2017 2382 WQEWYDLDSL-EQFPVPLGYDN---------NITPFQKLLILRCFRVDRV 2421 tyalrnFveekLpGekfvepdppldlskiyekeSspstPilFiLSPGaDP + a++++v ++ Gek+v+p p ++ i+e +S+p Pi+FiLSPG+DP KIAA2017 2422 YRAVTDYVTVTM-GEKYVQP-PMISFEAIFE-QSTPHSPIVFILSPGSDP 2468 skdvekLAkkmGFtfdnGkklhSiSLGQGQgpniAekaIetAaksGhWVl + d+ kLA+ G ++G++l+ +++GQGQ+ +A +++etA+ +G W + KIAA2017 2469 ATDLMKLAERSG---FGGNRLKFLAMGQGQEK-VALQLLETAVARGQWLM 2514 LQNiHLaasWLptLEKkLesltppegtHpdFRLFLTaEpaprPeehIfPi LQN+HL +WL++LEK Le++t+ +HpdFRL+LT+ p+ fPi KIAA2017 2515 LQNCHLLVKWLKDLEKSLERITK---PHPDFRLWLTTDPTKG-----FPI 2556 glLqnSiKiTNEPPtGlKANLlraysnDPIfdqeflemckkpaefkrllF g+Lq S+K+++EPP+GlK N++++y + ++ e+l++c++p +fk+l++ KIAA2017 2557 GILQKSLKVVTEPPNGLKLNMRATYFK---ISHEMLDQCPHP-AFKPLVY 2602 lLCfFHAVVqERRkFGPlGWNksYEFNesDLriSvdvldnyLeanakGRq +L+fFHAVVqERRkFG++GWN+ Y+FNesD+++++ l++yL++ + KIAA2017 2603 VLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQ--- 2649 NidpdkvPWeaLRYlfGeimYGGrItDdwDrRLLrtyLeefftpelfdgn ++++PW L+Yl+Ge+mYGGr D +DrR+L+ y +e+ +++fd++ KIAA2017 2650 -QRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTF 2698 adyeLapkidgdlgfavPpntdyeeYieyIeesLPsessPelfGLhpNAE +++ +++ + ++++P + + e+++e Ie+ LP +Pe+fGLhpNAE KIAA2017 2699 QPFHFFRN--KEVDYKIPVGDEKEKFVEAIEA-LPLANTPEVFGLHPNAE 2745 IgfltqeteklirtllelQpreaggeldggsgekvsrkkdssEEvvkqvl Ig++tq +++++ +llelQp + + +sg sr ++ + qv+ KIAA2017 2746 IGYYTQAARDMWAHLLELQPQTGE----SSSG--ISR-----DDYIGQVA 2784 rdileklpkklCqklFdkeelmlkrteeikdPlfvVlvQEiermNkLlke ++i k+p k Fd+++++++++++ +P+ vVl+QE+er+NkL+ KIAA2017 2785 KEIENKMP-----KVFDLDQVRKRLGTGL-SPTSVVLLQELERFNKLVVR 2828 irrSLkeLdlglkGeltmsndlEeliksLlngrVPaWDmWakksyPslkp +++SL+eL+++l Ge+ msn+l +++ sL++g +P W+++++ +lk+ KIAA2017 2829 MTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPN--IWRRLAPDTLKS 2876 LgsWvtDLlkRirQLqeWtedsGGAklglPkvvWLsGFFnPQsFLTAimQ Lg+W+ +l+R Q+ W ++ ++P+v WLsG+++P+s+LTA+ Q KIAA2017 2877 LGNWMVYFLRRFSQYMLWVTE------SEPSVMWLSGLHIPESYLTALVQ 2920 svARknkwPLDkLcLdteVtkkekeeqdskepPedGvyVhGLfLEGArWD +++Rkn+wPLD+ +L t Vtk+++ ++ ++ + +G++V+GL+LEGA WD KIAA2017 2921 ATCRKNGWPLDRSTLFTQVTKFQDADEVNER-AGQGCFVSGLYLEGADWD 2969 sktgllaeskpKeLfspmPViwlkavpasdkqetkdvyecPVYktkaRgg +++g l++skpK+L+ +P++ + +++a +++ +++++ PVY t+ R++ KIAA2017 2970 IEKGCLIKSKPKVLVVDLPILKIIPIEA-HRLKLQNTFRTPVYTTSMRRN 3018 vLSTTGHStnyvftfnLktkedtpaskWilaGVALllq<-* +++ +++vf+++L t + s+W+l+GV+L l+ KIAA2017 3019 AMG-----VGLVFEADLFTTR--HISHWVLQGVCLTLN 3049 //