hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-18432030/chunk_1/iprscan-20080502-18432030.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1997 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF03028.6.fs Dynein heavy chain 440.0 7.5e-133 2 PF03028.6.ls Dynein heavy chain 434.0 1.9e-127 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF03028.6.fs 1/2 985 1380 .. 1 444 [. 356.0 1.5e-107 PF03028.6.ls 1/1 985 1683 .. 1 783 [] 434.0 1.9e-127 PF03028.6.fs 2/2 1464 1683 .. 542 783 .] 84.0 1.1e-25 Alignments of top-scoring domains: PF03028.6.fs: domain 1 of 2, from 985 to 1380: score 356.0, E = 1.5e-107 *->lentypnpkvdwlsdqqWdsiarLseleeFrgLdddleknapdkrWk ++ +++++ +w+ +++ +++a L+ ++++L + l ++ + W+ KIAA1997 985 QQKIRDQLP-SWIDQERSWAVATLKI--ALPSLYQTLCFEDA-ALWR 1027 kwydseqPgEeeklPkeWkdeqklsidslkksaFqKLlllRalRPDRlty + y+++ + e+++P +k+s Fq +l+++ lRPDRl++ KIAA1997 1028 TYYNNSMC--EQEFPSILA---------KKVSLFQQILVVQVLRPDRLQS 1066 alrnFveekLpGekfvepdppldlskiyekeSspstPilFiLSPGaDPsk a++ F +++L G k v p pl+l++ y+ e+ + +Pil i SPGaDPs+ KIAA1997 1067 AMALFACKTL-GLKEVSP-LPLNLKRLYK-ETLEIEPILIIISPGADPSQ 1113 dvekLAkkmGFtfdnGkklhSiSLGQGQgpniAekaIetAaksGhWVlLQ ++ +LA ++G+ +h +++GQGQ +A +++++ a++G W +L+ KIAA1997 1114 ELQELANAE----RSGECYHQVAMGQGQAD-LAIQMLKECARNGDWLCLK 1158 NiHLaasWLptLEKkLesltppegtHpdFRLFLTaEpaprPeehIfPigl N HL+ sWLp LEK L l+p FRL+LTaE +p+ f l KIAA1997 1159 NLHLVVSWLPVLEKELNTLQP----KDTFRLWLTAEVHPN-----FTPIL 1199 LqnSiKiTNEPPtGlKANLlraysnDPIfdqeflemckkp.aefkrllFl Lq+S+KiT+E P+GlK NL+r+y + ++e++ k+++ ++ lF+ KIAA1997 1200 LQSSLKITYESPPGLKKNLMRTYES---WTPEQISK--KDnTHRAHALFS 1244 LCfFHAVVqERRkFGPlGWNksYEFNesDLriSvdvldnyLeanakGRqN L++FHA qERR+++P+GW+k+YEF+ sDLr ++ +d+ + KIAA1997 1245 LAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGA------ 1288 idpdkvPWeaLRYlfGeimYGGrItDdwDrRLLrtyLeefftpelfd... + v We++ +l+ ++YGGrI++++D R+L++yL +ff+ +++d + KIAA1997 1289 ---KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDvfn 1335 gnadyeLapkidgdlgfavPpntdyeeYieyIeesLPsessPelfGLhpN ++ + +p+ + ++P++ ++ +Y Ie+ P+ + P fGL++N KIAA1997 1336 QRNKKSIFPY-----SVSLPQSCSILDYRAVIEK-IPEDDKPSFFGLPAN 1379 A<-* + KIAA1997 1380 I 1380 PF03028.6.ls: domain 1 of 1, from 985 to 1683: score 434.0, E = 1.9e-127 *->lentypnpkvdwlsdqqWdsiarLseleeFrgLdddleknapdkrWk ++ +++++ +w+ +++ +++a L+ ++++L + l ++ + W+ KIAA1997 985 QQKIRDQLP-SWIDQERSWAVATLKI--ALPSLYQTLCFEDA-ALWR 1027 kwydseqPgEeeklPkeWkdeqklsidslkksaFqKLlllRalRPDRlty + y+++ + e+++P +k+s Fq +l+++ lRPDRl++ KIAA1997 1028 TYYNNSMC--EQEFPSILA---------KKVSLFQQILVVQVLRPDRLQS 1066 alrnFveekLpGekfvepdppldlskiyekeSspstPilFiLSPGaDPsk a++ F +++L G k v p pl+l++ y+ e+ + +Pil i SPGaDPs+ KIAA1997 1067 AMALFACKTL-GLKEVSP-LPLNLKRLYK-ETLEIEPILIIISPGADPSQ 1113 dvekLAkkmGFtfdnGkklhSiSLGQGQgpniAekaIetAaksGhWVlLQ ++ +LA ++G+ +h +++GQGQ +A +++++ a++G W +L+ KIAA1997 1114 ELQELANAE----RSGECYHQVAMGQGQAD-LAIQMLKECARNGDWLCLK 1158 NiHLaasWLptLEKkLesltppegtHpdFRLFLTaEpaprPeehIfPigl N HL+ sWLp LEK L l+p FRL+LTaE +p+ f l KIAA1997 1159 NLHLVVSWLPVLEKELNTLQP----KDTFRLWLTAEVHPN-----FTPIL 1199 LqnSiKiTNEPPtGlKANLlraysnDPIfdqeflemckkp.aefkrllFl Lq+S+KiT+E P+GlK NL+r+y + ++e++ k+++ ++ lF+ KIAA1997 1200 LQSSLKITYESPPGLKKNLMRTYES---WTPEQISK--KDnTHRAHALFS 1244 LCfFHAVVqERRkFGPlGWNksYEFNesDLriSvdvldnyLeanakGRqN L++FHA qERR+++P+GW+k+YEF+ sDLr ++ +d+ + KIAA1997 1245 LAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGA------ 1288 idpdkvPWeaLRYlfGeimYGGrItDdwDrRLLrtyLeefftpelfd... + v We++ +l+ ++YGGrI++++D R+L++yL +ff+ +++d + KIAA1997 1289 ---KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDvfn 1335 gnadyeLapkidgdlgfavPpntdyeeYieyIeesLPsessPelfGLhpN ++ + +p+ + ++P++ ++ +Y Ie+ P+ + P fGL++N KIAA1997 1336 QRNKKSIFPY-----SVSLPQSCSILDYRAVIEK-IPEDDKPSFFGLPAN 1379 AEIgfltqeteklirtllelQpreaggeldggsgekvsrkkdssEEvvkq + ++ + + + i+ l+ l r+ +gs+ r E+ ++ KIAA1997 1380 IARSSQRMISSQVISQLRILG-RSIT----AGSK--FDR------EIWSN 1416 vlrdileklpkklCqklFdkeelmlkrt.e..eikdPlfvVlvQEiermN l+ +l +++ kl + + ++ +k+++ ++++ +P+ + + E ++ KIAA1997 1417 ELSPVLNLWK-KL---NQNSNLIHQKVPpPndRQGSPILSFIILEQFNAI 1462 kLlkeirrSLkeLdlglkGeltmsndlEeliksLlngrVPa.WD.mWakk L++ +++SL+ L+++++G+ + s+++++l+++Lln++ P W ++W ++ KIAA1997 1463 RLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLaWQsKWEGP 1512 syPslkpLgsWvtDLlkRirQLqeWtedsGGAklglPkvvWLsGFFnPQs +P +++ L++R +q+W +++ +l+++ +Ls +F P + KIAA1997 1513 EDPL-----QYLRGLVARALAIQNWVDKA-EKQALLSETLDLSELFHPDT 1556 FLTAimQsvARknkwPLDkLcLdteVtkkekeeqdskepPedGvyVhGLf FL+A++Q++AR+ + + D L++ + + +e ++ + ++GL KIAA1997 1557 FLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQ-------IKISGLL 1599 LEGArWDsktgllaeskp......KeLfspmPViwlkavpasdkqetkdv LEG +D+ ++l e+ +++++ +++L + m i +a+ + +++ KIAA1997 1600 LEGCSFDG--NQLSENQLdspsvsSVLPCFMGWIPQDACGP---YSPDEC 1644 yecPVYktkaRggvLSTTGHStnyvftfnLktkedtpaskWilaGVALll +++PVY ++R + v+ +++++ ++++Wi+ G AL+l KIAA1997 1645 ISLPVYTSAERDR----------VVTNIDVPCGG--NQDQWIQCGAALFL 1682 q<-* KIAA1997 1683 K 1683 PF03028.6.fs: domain 2 of 2, from 1464 to 1683: score 84.0, E = 1.1e-25 *->LlkeirrSLkeLdlglkGeltmsndlEeliksLlngrVPa.WD.mWa L++ +++SL+ L+++++G+ + s+++++l+++Lln++ P W ++W KIAA1997 1464 LVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLaWQsKWE 1510 kksyPslkpLgsWvtDLlkRirQLqeWtedsGGAklglPkvvWLsGFFnP ++ +P +++ L++R +q+W +++ +l+++ +Ls +F P KIAA1997 1511 GPEDPL-----QYLRGLVARALAIQNWVDKA-EKQALLSETLDLSELFHP 1554 QsFLTAimQsvARknkwPLDkLcLdteVtkkekeeqdskepPedGvyVhG +FL+A++Q++AR+ + + D L++ + + +e ++ + ++G KIAA1997 1555 DTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQ-------IKISG 1597 LfLEGArWDsktgllaeskp......KeLfspmPViwlkavpasdkqetk L LEG +D+ ++l e+ +++++ +++L + m i +a+ + ++ KIAA1997 1598 LLLEGCSFDG--NQLSENQLdspsvsSVLPCFMGWIPQDACGP---YSPD 1642 dvyecPVYktkaRggvLSTTGHStnyvftfnLktkedtpaskWilaGVAL + +++PVY ++R + v+ +++++ ++++Wi+ G AL KIAA1997 1643 ECISLPVYTSAERDR----------VVTNIDVPCGG--NQDQWIQCGAAL 1680 llq<-* +l KIAA1997 1681 FLK 1683 //