# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/pf00647.fasta.huge -Q ../query/KIAA1985.ptfa ./tmplib.25089 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1985, 955 aa
 vs ./tmplib.25089 library

1986550 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 4.6130+/-0.00502; mu= 18.3225+/- 0.343
 mean_var=91.1733+/-21.292, 0's: 0 Z-trim: 1  B-trim: 9 in 1/39
 Lambda= 0.134320

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 39, opt: 27, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA1043  ( 2126 res)   af02720                    (2126)  171 44.5 0.00016


>>KIAA1043  ( 2126 res)   af02720                         (2126 aa)
 initn: 252 init1: 100 opt: 171  Z-score: 172.9  bits: 44.5 E(): 0.00016
Smith-Waterman score: 340;  24.528% identity (53.208% similar) in 530 aa overlap (400-922:17-524)

     370       380       390       400       410       420         
KIAA19 GMSLPIWQVHLVLQNTTKLLGFPSPGWGEVSALACPMLRQALAACEELADRSTQRALCLI
                                     .:. :   .: :   ..:...  .      
KIAA10               ELGNMGAVYIAMGDFENAVQCH--EQHLKIAKDLGNKREEARAYSN
                             10        20          30        40    

     430       440       450       460        470       480        
KIAA19 LSKVYLEHRSPDGAIHYLSQALVLGQLLGEQE-SFESSLCLAWAYLLASQAKKALDVLEP
       :...:  .:. : :. : . .: :.: : :.   ...   :. :    .. ..: .  : 
KIAA10 LGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQ
           50        60        70        80        90       100    

      490       500       510       520       530       540        
KIAA19 LLCSLKETESLTQRGVIYNLLGLALQGEGRVNRAAKSYLRALNRAQEVGDVHNQAVAMAN
        :   .. .. . .:   . ::.  : .:  . : : .   :  :::..:   :. :..:
KIAA10 QLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGN
          110       120       130       140       150       160    

      550       560       570        580       590           600   
KIAA19 LGHLSLKSWAQHPARNYLLQAVRLY-CELQASKETDMELVQVF----LWLAQVLVSGHQL
       .:.        . : ..  :::. .  ::: : :.. .  :.     : .:   ...:. 
KIAA10 MGN-------AYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHD-
                 170       180       190       200       210       

           610       620       630       640       650       660   
KIAA19 THGLLCYEMALLFGLRHRHLKSQLQATKSLCHFYSSVSPNPEACITYHEHWLALAQQLRD
        ..:  :.  : .. . : ..:. .: ..: .:. : .   .:   :.:..: :: .:.:
KIAA10 -RALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAA-PYYEQYLRLAPDLQD
         220       230       240       250        260       270    

           670       680       690       700       710       720   
KIAA19 REMEGRLLESLGQLYRNLNTARSLRRSLTCIKESLRIFIDLGETDKAAEAWLGAGRLHYL
        : ::.. ..::  .  :.   . ....   ...: .  :: .  . :.:. . :     
KIAA10 MEGEGKVCHNLGYAHYCLG---NYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKA
          280       290          300       310       320       330 

           730       740       750       760       770       780   
KIAA19 MQEDELVELCLQAAIQTALKSEEPLLALKLYEEAGDVFFNGTRHRHHAVEYYRAGAVPLA
       . .   .: : .  .. : . ..    ..   . ::.:.   .  . :...:.   . ::
KIAA10 LLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFIC-KKDINGAIKFYEQ-QLGLA
             340       350       360       370        380          

           790       800       810       820       830       840   
KIAA19 RRLKAVRTELRIFNKLTELQISLEGYEKALEFATLAARLSTITGDQRQELVAFHRLATVY
       ...:  : :   .  :      .. :.::: . :   ..    .:   :  :  .::.::
KIAA10 HQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVY
     390       400       410       420       430       440         

           850       860       870       880       890       900   
KIAA19 YSLHMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYYRLGRLTFCQLKDAHDATEYFLL
       ..:  : ::  :: . :.:     :. :.    :.::  .: .:  ...  ..:  ::  
KIAA10 MALGKYTMAFKCYEEQLDLG----QKLKDPSLEAQVYGNMG-ITKMNMNVMEEAIGYFEQ
     450       460           470       480        490       500    

           910        920       930       940       950            
KIAA19 ALAAAVLL-GDEELQDTIRSRLDNICQSPLWHSRPSGCSSERARWLSGGGLAL       
        ::    : :.: . :  :.                                        
KIAA10 QLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKA
          510       520       530       540       550       560    




955 residues in 1 query   sequences
1986550 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:24:30 2008 done: Thu Dec 18 15:24:31 2008
 Total Scan time:  0.660 Total Display time:  0.050

Function used was FASTA [version 34.26.5 April 26, 2007]