# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/fg00781.fasta.huge -Q ../query/KIAA1942.ptfa ./tmplib.25089 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA1942, 445 aa
vs ./tmplib.25089 library
1987060 residues in 2037 sequences
Expectation_n fit: rho(ln(x))= 6.7023+/-0.00633; mu= 4.3960+/- 0.427
mean_var=152.2240+/-39.134, 0's: 0 Z-trim: 12 B-trim: 136 in 1/39
Lambda= 0.103952
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 37, opt: 25, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2037)
KIAA1242 ( 504 res) fh10406 ( 504) 218 44.4 2e-05
KIAA0925 ( 479 res) hh02949 ( 479) 186 39.6 0.00053
KIAA1374 ( 764 res) fj04345 ( 764) 181 39.0 0.0012
KIAA0199 ( 1283 res) ha03150s1 (1283) 170 37.6 0.0056
KIAA1645 ( 386 res) fg04139 ( 386) 161 35.7 0.0062
>>KIAA1242 ( 504 res) fh10406 (504 aa)
initn: 129 init1: 75 opt: 218 Z-score: 189.3 bits: 44.4 E(): 2e-05
Smith-Waterman score: 235; 26.180% identity (55.794% similar) in 233 aa overlap (218-443:245-458)
190 200 210 220 230 240
KIAA19 EPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKN-IHLWTPTDG
.. :: : : :.. .:. ...: . :
KIAA12 GLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER--GNLVAVGTHKGFVQIWDAAAG
220 230 240 250 260 270
250 260 270 280 290 300
KIAA19 GSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAH
. . . ::: : : :. . ..: : : : :::. : .. .:
KIAA12 KKLSMLE----GHTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSE--RRLQGH
280 290 300 310 320
310 320 330 340 350 360
KIAA19 DGDVNVISWSRQEPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSG
.: ..:: .. .: :::.:. : .:. .: ::: . .:.: : .. : :.. :
KIAA12 RQEVCGLKWSTDHQLLASGGNDNKLLVWN---HSSLSPVQQYTEHLAAVKAIAWSPHQHG
330 340 350 360 370 380
370 380 390 400 410 420
KIAA19 VFAASG--ADHQITQWDLAVERDP----EAGDVEADPGLADLPQQLLFVHQGETELKELH
..:..: ::. : :. .. .: ..:. . . . ..:. .: : .. . :
KIAA12 LLASGGGTADRCIRFWN-TLTGQPLQCIDTGSQVCNLAWSKHANELVSTH-GYSQNQILV
390 400 410 420 430
430 440
KIAA19 WHPQCPGLLVSTALSGFTIFRTISV
: . :.: . :.: . .:..
KIAA12 W--KYPSLTQVAKLTGHS-YRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVS
440 450 460 470 480 490
>>KIAA0925 ( 479 res) hh02949 (479 aa)
initn: 294 init1: 133 opt: 186 Z-score: 163.7 bits: 39.6 E(): 0.00053
Smith-Waterman score: 186; 28.226% identity (59.677% similar) in 124 aa overlap (258-377:84-203)
230 240 250 260 270 280
KIAA19 RLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRI
:: .: :..:.: ....:::: :.:.::
KIAA09 IVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRI
60 70 80 90 100 110
290 300 310 320 330 340
KIAA19 WDIRAAPSKACM---LTTATAHDGDVNVISWS-RQEPFLLSGGDDGALKIWDLRQFKSGS
:.: . : : : .:. :... : . .:.:.: : . ::.: :
KIAA09 WEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNL---DVGE
120 130 140 150 160 170
350 360 370 380 390 400
KIAA19 PVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLP
:: . :. . . .. :....... :...
KIAA09 PVKMIDCHTDVILCMSFNT-DGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVF
180 190 200 210 220
410 420 430 440
KIAA19 QQLLFVHQGETELKELHWHPQCPGLLVSTALSGFTIFRTISV
KIAA09 LGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGK
230 240 250 260 270 280
>>KIAA1374 ( 764 res) fj04345 (764 aa)
initn: 98 init1: 98 opt: 181 Z-score: 157.1 bits: 39.0 E(): 0.0012
Smith-Waterman score: 201; 25.131% identity (54.974% similar) in 191 aa overlap (208-393:88-259)
180 190 200 210 220 230
KIAA19 ALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKN
: .: : .: :. . :. . .:. . .
KIAA13 VKKQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGE-DGQ
60 70 80 90 100 110
240 250 260 270 280 290
KIAA19 IHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKA
:..:. : . . .. . : .. :.: . :. . . . :. . :.
KIAA13 IKIWSKTG-----MLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQ----PNAK
120 130 140 150 160
300 310 320 330 340 350
KIAA19 CMLTTATAHDGDVNVISWSRQEPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTS
. :::: . ..:. . ..::.:.: :.:: . : :. . . : :.::
KIAA13 VL--QWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWD----SYGRPLYNSQPHEHPITS
170 180 190 200 210 220
360 370 380 390 400 410
KIAA19 VEWHPQDSGVFAASGADHQI-----TQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQG
: : : :. .::. :. : . : :. :.:. :..:..
KIAA13 VAWAP-DGELFAV-GSFHTLRLCDKTGWSYALEK-PNTGSIFNIAWSIDGTQIAGACGNG
230 240 250 260 270
420 430 440
KIAA19 ETELKELHWHPQCPGLLVSTALSGFTIFRTISV
KIAA13 HVVFAHVVEQHWEWKNFQVTLTKRRAMQVRNVLNDAVDLLEFRDRVIKASLNYAHLVVST
280 290 300 310 320 330
>>KIAA0199 ( 1283 res) ha03150s1 (1283 aa)
initn: 134 init1: 71 opt: 170 Z-score: 145.3 bits: 37.6 E(): 0.0056
Smith-Waterman score: 174; 25.495% identity (48.762% similar) in 404 aa overlap (3-381:818-1190)
10 20
KIAA19 AARKGR-RRTCETGEPMEA-ESGDTSSEG-PA
: :: :: .: .:: :: . :.: :
KIAA01 SDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKA
790 800 810 820 830 840
30 40 50 60 70 80
KIAA19 QVYLPGRGPPLREGEELVMDEEAYVLYHRAQTGAPCL---SFDIVRDHLGDNRTELPLTL
:: .::::. . :. : :: .:. .. : :
KIAA01 GPEEPGDSPPLRHRPR---GPPPPSLFGD-QPDLTCLIDTNFSAQPRSSQPTQPE-PRHR
850 860 870 880 890 900
90 100 110 120 130
KIAA19 YLCAGTQAESAQSNRLMMLRMHNLHGTK----P---PPSEGSDEEEEEEDEEDEEERKPQ
.:. .. . . .. :... .: : ::: : . ::: : : .
KIAA01 AVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPE-KGS
910 920 930 940 950 960
140 150 160 170 180 190
KIAA19 LELAMVPHY-GGINRVRVSWLGEEPVAGVWSEKGQVEVF-ALRRLLQVVEEP--QALAA-
:: .: :.: .... :. :.: : :..::. :.. .: : ....:
KIAA01 PSLAWAPSAEGSIWSLELQ--GNLIVVGRSS--GRLEVWDAIEGVLCCSSEEVSSGITAL
970 980 990 1000 1010
200 210 220 230 240
KIAA19 -FL--RDEQAQMK---PIFSFAGHMGEGFALDWSP-RVTGRLLTGDCQKNIHLWTPTDGG
:: : :... .::. : :: :: . : :. . ... .:
KIAA01 VFLDKRIVAARLNGSLDFFSLETHT----AL--SPLQFRGTPGRGSSPAS-PVYSSSDTV
1020 1030 1040 1050 1060 1070
250 260 270 280 290 300
KIAA19 SWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHD
. :. . .: . . :. . . ... : : ..:.. .. .: : : .:.
KIAA01 ACHLTHTVPCAHQKPITALKAAAGR---LVTGSQDHTLRVFRLE----DSCCLFTLQGHS
1080 1090 1100 1110 1120
310 320 330 340 350 360
KIAA19 GDVNVISWSRQEPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGV
: .... . : : :::.:::. .::. .:: :. : . :::. ..
KIAA01 GAITTV-YIDQTMVLASGGQDGAICLWDV---LTGSRVSHVFAHRGDVTSLT---CTTSC
1130 1140 1150 1160 1170
370 380 390 400 410 420
KIAA19 FAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELHWHPQCPG
.:: : :. ::
KIAA01 VISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDL
1180 1190 1200 1210 1220 1230
>>KIAA1645 ( 386 res) fg04139 (386 aa)
initn: 106 init1: 62 opt: 161 Z-score: 144.6 bits: 35.7 E(): 0.0062
Smith-Waterman score: 161; 24.481% identity (55.602% similar) in 241 aa overlap (204-426:117-346)
180 190 200 210 220 230
KIAA19 VEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVT-GR-LLT
. . .. :: :. . : . :: ::.
KIAA16 FCEGAQAQGRPLLFSGSQSGLVHIWSLQTRRAVTTLDGHGGQ--CVTWLQTLPQGRQLLS
90 100 110 120 130 140
240 250 260 270 280
KIAA19 GDCQKNIHLWTPTDGGSWHVDQRPF--VGHTRSVEDLQWSPTENTVFASCSADASIRIWD
. .. :: ..: : ::. . :: :: .: . . . ..: ..: .
KIAA16 QGRDLKLCLWDLAEGRSAVVDSVCLESVGFCRSSILAGGQPRWTLAVPGRGSDE-VQILE
150 160 170 180 190 200
290 300 310 320 330 340
KIAA19 IRAAPSKA--CMLTT-ATAHDG-DVNVISWS---RQEPFLLSGGDDGALKIWDLRQFKSG
. :::. : : : :. : . . :. ..:.::.: .::.. .::. . :
KIAA16 M---PSKTSVCALKPKADAKLGMPMCLRLWQADCSSRPLLLAGYEDGSVVLWDVSEQKVC
210 220 230 240 250 260
350 360 370 380 390
KIAA19 SPVATFKQHVAPVTSVEWHPQDS-GVFAASGADHQITQWDLAVERDPEA-GDVE-ADPGL
: .: : :: .... : . :. ...: . .. :.: .. .. : : ..::.
KIAA16 SRIAC---HEEPVMDLDFDSQKARGISGSAG--KALAVWSLDWQQALQVRGTHELTNPGI
270 280 290 300 310
400 410 420 430 440
KIAA19 ADL---PQQLLFVHQG-ETELKELHWHPQCPGLLVSTALSGFTIFRTISV
:.. :.. ... : . ... .::. . :
KIAA16 AEVTIRPDRKILATAGWDHRIRVFHWRTMQPLAVLAFHSAAVQCVAFTADGLLAAGSKDQ
320 330 340 350 360 370
KIAA16 RISLWSLYPRA
380
445 residues in 1 query sequences
1987060 residues in 2037 library sequences
Scomplib [34.26]
start: Thu Dec 18 15:22:58 2008 done: Thu Dec 18 15:22:59 2008
Total Scan time: 0.420 Total Display time: 0.040
Function used was FASTA [version 34.26.5 April 26, 2007]