hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-15295776/chunk_1/iprscan-20080502-15295776.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1883 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF07714.7.ls Protein tyrosine kinase 262.5 7.8e-76 1 PF07714.7.fs Protein tyrosine kinase 260.7 1.6e-75 1 PF00069.15.fs Protein kinase domain 86.3 2.2e-24 1 PF00069.15.ls Protein kinase domain 88.2 2.4e-23 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF07714.7.fs 1/1 153 428 .. 1 272 [] 260.7 1.6e-75 PF00069.15.fs 1/1 153 428 .. 1 287 [] 86.3 2.2e-24 PF00069.15.ls 1/1 153 428 .. 1 287 [] 88.2 2.4e-23 PF07714.7.ls 1/1 153 428 .. 1 272 [] 262.5 7.8e-76 Alignments of top-scoring domains: PF07714.7.fs: domain 1 of 1, from 153 to 428: score 260.7, E = 1.6e-75 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie l+ ++++G+G FG+V +G+ + d t +V VK L+ +a + e KIAA1883 153 LSYLQEIGSGWFGKVILGEIF--SDYTPAQVVVKELRA-SAGPLE-- 194 redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL +++F++EA+ ++l +HpN++++lG c++ P ++++E++++GdL KIAA1883 195 QRKFISEAQPYRSL-QHPNVLQCLGLCVE-TLP----FLLIMEFCQLGDL 238 ldfLrkhr.......egrpLtlkdLlsfalQiAkGMeYLesknfvHRDLA + +Lr++r++++ ++e +p +l +L + l+iA+G+++L+s+n+vH DLA KIAA1883 239 KRYLRAQRppeglspELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLA 288 ARNcLVsenlvVKIsDFGLaRdiynddyYvrkkgggklPvkWmAPEslky RNcL++++l+V+I+D GLa y++dyY + + +P +W APE l + KIAA1883 289 LRNCLLTSDLTVRIGDYGLAHSNYKEDYY-LTPERLWIPLRWAAPELLGE 337 gk.......FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyed ++ + + +S +WS GV+LWE+f +G+qP Y +s+eevl++++++ KIAA1883 338 LHgtfmvvdQSRESNIWSLGVTLWELFEFGAQP-YRHLSDEEVLAFVVRQ 386 ......GyRLprPenCPdelYdlMlqCWaedPedRPtFselveeL<-* ++ + + RL+ P d Yd++++CW + P++RP+ s+l+ +L KIAA1883 387 qhvklaRPRLKLPY--ADYWYDILQSCW-RPPAQRPSASDLQLQL 428 PF00069.15.fs: domain 1 of 1, from 153 to 428: score 86.3, E = 2.2e-24 *->yelleklGsGsfGtVykakhkgtgk..iVAvKiikkrkekskkdkta + l+ +GsG fG+V ++ ++ + +V+vK+++ + + + +++ KIAA1883 153 LSYLQEIGSGWFGKVILGEIFSDYTpaQVVVKELRAS-AGPLEQRKF 198 rrlsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdyl + E+q ++L+HpN++++++ + + l++E+c+ G dL++yl KIAA1883 199 IS--EAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLG----DLKRYL 242 s.....e..trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPe + ++++e+ + + p + ++++++ l+i+rgl++LHs++ +H DL + KIAA1883 243 RaqrppEglSPELPPR--DLRTLQRMGLEIARGLAHLHSHNYVHSDLALR 290 NILldnngvvdaflKiaDFGlAkkls......t.sss.lttfvGTpwYmA N+Ll ++ +v +i+D GlA +s+ +++ + ++l+ + ++++A KIAA1883 291 NCLLTSDLTV----RIGDYGLA--HSnykedyYlTPErLWIP---LRWAA 331 PEvll......ggngygtkvDvWSlGvilyellt.GkpPFsgevqds.ld PE+l + +++ + ++++ +WSlGv+l+el+ G P+++ s+ KIAA1883 332 PELLGelhgtfMVVDQSRESNIWSLGVTLWELFEfGAQPYRHL---SdEE 378 qlqlirkilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDP l+ +++ + +l +++ + + d++ +c+++ P KIAA1883 379 VLAFVVRQQHVKLARPRLKLPY------------ADYWYDILQSCWRP-P 415 skRltaeeilqHPwf<-* ++R++a ++ + KIAA1883 416 AQRPSASDLQLQ--L 428 PF00069.15.ls: domain 1 of 1, from 153 to 428: score 88.2, E = 2.4e-23 *->yelleklGsGsfGtVykakhkgtgk..iVAvKiikkrkekskkdkta + l+ +GsG fG+V ++ ++ + +V+vK+++ + + + +++ KIAA1883 153 LSYLQEIGSGWFGKVILGEIFSDYTpaQVVVKELRAS-AGPLEQRKF 198 rrlsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdyl + E+q ++L+HpN++++++ + + l++E+c+ G dL++yl KIAA1883 199 IS--EAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLG----DLKRYL 242 s.....e..trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPe + ++++e+ + + p + ++++++ l+i+rgl++LHs++ +H DL + KIAA1883 243 RaqrppEglSPELPPR--DLRTLQRMGLEIARGLAHLHSHNYVHSDLALR 290 NILldnngvvdaflKiaDFGlAkkls......t.sss.lttfvGTpwYmA N+Ll ++ +v +i+D GlA +s+ +++ + ++l+ + ++++A KIAA1883 291 NCLLTSDLTV----RIGDYGLA--HSnykedyYlTPErLWIP---LRWAA 331 PEvll......ggngygtkvDvWSlGvilyellt.GkpPFsgevqds.ld PE+l + +++ + ++++ +WSlGv+l+el+ G P+++ s+ KIAA1883 332 PELLGelhgtfMVVDQSRESNIWSLGVTLWELFEfGAQPYRHL---SdEE 378 qlqlirkilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDP l+ +++ + +l +++ + + d++ +c+++ P KIAA1883 379 VLAFVVRQQHVKLARPRLKLPY------------ADYWYDILQSCWRP-P 415 skRltaeeilqHPwf<-* ++R++a ++ + KIAA1883 416 AQRPSASDLQLQ--L 428 PF07714.7.ls: domain 1 of 1, from 153 to 428: score 262.5, E = 7.8e-76 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie l+ ++++G+G FG+V +G+ + d t +V VK L+ +a + e KIAA1883 153 LSYLQEIGSGWFGKVILGEIF--SDYTPAQVVVKELRA-SAGPLE-- 194 redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL +++F++EA+ ++l +HpN++++lG c++ P ++++E++++GdL KIAA1883 195 QRKFISEAQPYRSL-QHPNVLQCLGLCVE-TLP----FLLIMEFCQLGDL 238 ldfLrkhr.......egrpLtlkdLlsfalQiAkGMeYLesknfvHRDLA + +Lr++r++++ ++e +p +l +L + l+iA+G+++L+s+n+vH DLA KIAA1883 239 KRYLRAQRppeglspELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLA 288 ARNcLVsenlvVKIsDFGLaRdiynddyYvrkkgggklPvkWmAPEslky RNcL++++l+V+I+D GLa y++dyY + + +P +W APE l + KIAA1883 289 LRNCLLTSDLTVRIGDYGLAHSNYKEDYY-LTPERLWIPLRWAAPELLGE 337 gk.......FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyed ++ + + +S +WS GV+LWE+f +G+qP Y +s+eevl++++++ KIAA1883 338 LHgtfmvvdQSRESNIWSLGVTLWELFEFGAQP-YRHLSDEEVLAFVVRQ 386 ......GyRLprPenCPdelYdlMlqCWaedPedRPtFselveeL<-* ++ + + RL+ P d Yd++++CW + P++RP+ s+l+ +L KIAA1883 387 qhvklaRPRLKLPY--ADYWYDILQSCW-RPPAQRPSASDLQLQL 428 //