hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-14454983/chunk_1/iprscan-20080502-14454983.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1857 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00053.14.ls Laminin EGF-like (Domains III and V) 106.9 5.4e-29 3 PF00053.14.fs Laminin EGF-like (Domains III and V) 101.5 9.1e-29 3 PF00055.8.fs Laminin N-terminal (Domain VI) 50.4 3.8e-15 2 PF00055.8.ls Laminin N-terminal (Domain VI) 30.0 5.1e-11 1 PF00008.17.fs EGF-like domain 38.9 5.2e-10 3 PF07974.3.fs EGF-like domain 32.2 5.2e-08 3 PF00008.17.ls EGF-like domain 35.6 1.6e-07 3 PF07974.3.ls EGF-like domain 33.1 9.1e-07 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00055.8.ls 1/1 58 304 .. 1 264 [] 30.0 5.1e-11 PF00055.8.fs 1/2 156 220 .. 113 181 .. 40.8 3e-12 PF00053.14.fs 1/3 306 363 .. 1 59 [] 33.5 4.9e-09 PF00053.14.ls 1/3 306 363 .. 1 59 [] 35.3 2e-07 PF00053.14.fs 2/3 372 425 .. 1 59 [] 26.9 3.8e-07 PF00053.14.ls 2/3 372 425 .. 1 59 [] 28.8 1.8e-05 PF00053.14.ls 3/3 428 470 .. 1 59 [] 42.8 1.1e-09 PF00053.14.fs 3/3 428 470 .. 1 59 [] 41.1 3e-11 PF00008.17.fs 3/3 475 505 .. 1 38 [] 25.8 2.6e-06 PF07974.3.ls 2/2 475 505 .. 1 37 [] 25.3 0.0002 PF00008.17.ls 3/3 475 505 .. 1 38 [] 27.6 4.2e-05 Alignments of top-scoring domains: PF00055.8.ls: domain 1 of 1, from 58 to 304: score 30.0, E = 5.1e-11 *->CyPAtgNLainradrlsats.TCGlhsPEeyCilshlqpGRPVrdKk C P + L ++ +++ + TCG + PE++C sh +p KIAA1857 58 CQPKVMRLKDYVKVKVEPSGiTCGDP-PERFC--SHENP------YL 95 C.flCDsnspnkrddnpnsHpisflvdttnpqrlttWWQSetmlnGvqYp C+ CD+ p + Hp+ d l t WQS Yp KIAA1857 96 CsNECDASNPD------LAHPPRLMFDKEE-EGLATYWQSI---TWSRYP 135 n..nVTitLDLeaeFhiT.YvIikFkNtfRPEaamiieRSsDfGktWipY ++ ++itL + T+ v ++F RP m +e S+D G+tW pY KIAA1857 136 SplEANITLSWNKTVELTdDVVMTFE-YGRP-TVMVLEKSLDNGRTWQPY 183 qYYaydDsECeatYpgiprrpirtgraedd.vlCTSrYSdiePl.teGEV q+Ya d C + + rr+ +++vlCT +YS+ ++ e V KIAA1857 184 QFYAED---CMEAFGMSARRARDMSSSSAHrVLCTEEYSRWAGSkKEKHV 230 iFsvLeGR......PsadifDpY......SprlQewlkaTniRitLtRLh F v + R +P + D+ ++ +++ l e+ + T++R +L R KIAA1857 231 RFEVRD-RfaifagPDLRNMDNLytrlesAKGLKEFFTLTDLRMRLLR-P 278 TLGDnLldsSHRelkeLdpevlekYYYAIsDivVGG<-* LG +e+l kY+YAIs+i V G KIAA1857 279 ALGGTYVQ----------RENLYKYFYAISNIEVIG 304 PF00055.8.fs: domain 1 of 2, from 156 to 220: score 40.8, E = 3e-12 *->vIikFkNtfRPEaamiieRSsDfGktWipYqYYaydDsECeatYpgi v ++F RP m +e S+D G+tW pYq+Ya d C + + KIAA1857 156 VVMTFE-YGRP-TVMVLEKSLDNGRTWQPYQFYAED---CMEAFGMS 197 prrpirtgraedd.vlCTSrYSd<-* rr+ +++vlCT +YS+ KIAA1857 198 ARRARDMSSSSAHrVLCTEEYSR 220 PF00053.14.fs: domain 1 of 3, from 306 to 363: score 33.5, E = 4.9e-09 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C Cn+h+ C + + qC C +n+tG++C Ck ++ KIAA1857 306 CKCNLHA----NLCSMREG-----SLQCE-CEHNTTGPDCGKCKKNF 342 yglpsg.........dpgqgC<-* ++++ ++ + ++++++ C KIAA1857 343 RTRSWRagsylplphGSPNAC 363 PF00053.14.ls: domain 1 of 3, from 306 to 363: score 35.3, E = 2e-07 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C Cn+h+ C + + qC C +n+tG++C Ck ++ KIAA1857 306 CKCNLHA----NLCSMREG-----SLQCE-CEHNTTGPDCGKCKKNF 342 yglpsg.........dpgqgC<-* ++++ ++ + ++++++ C KIAA1857 343 RTRSWRagsylplphGSPNAC 363 PF00053.14.fs: domain 2 of 3, from 372 to 425: score 26.9, E = 3.8e-07 *->CdCnphGslsddtCdsddelf..geetGqClkCkpnvtGrrCdrCkp C+C +h+ +C s + ++ + C+ Ck+n+ G++C +C+ KIAA1857 372 CECYGHS----NRC-S----YidFLNVVTCVSCKHNTRGQHCQHCRL 409 Gyyglpsg..dpgqgC<-* Gyy++ s++ d ++ C KIAA1857 410 GYYRNGSAelDDENVC 425 PF00053.14.ls: domain 2 of 3, from 372 to 425: score 28.8, E = 1.8e-05 *->CdCnphGslsddtCdsddelf..geetGqClkCkpnvtGrrCdrCkp C+C +h+ +C s + ++ + C+ Ck+n+ G++C +C+ KIAA1857 372 CECYGHS----NRC-S----YidFLNVVTCVSCKHNTRGQHCQHCRL 409 Gyyglpsg..dpgqgC<-* Gyy++ s++ d ++ C KIAA1857 410 GYYRNGSAelDDENVC 425 PF00053.14.ls: domain 3 of 3, from 428 to 470: score 42.8, E = 1.1e-09 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+Cn Gs++ d+C+ tG C C+++ +G++Cd C+p + KIAA1857 428 CNCNQIGSVH-DRCNE--------TGFCE-CREGAAGPKCDDCLPTH 464 yglpsgdpgqgC<-* y ++qgC KIAA1857 465 Y------WRQGC 470 PF00053.14.fs: domain 3 of 3, from 428 to 470: score 41.1, E = 3e-11 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+Cn Gs++ d+C+ tG C C+++ +G++Cd C+p + KIAA1857 428 CNCNQIGSVH-DRCNE--------TGFCE-CREGAAGPKCDDCLPTH 464 yglpsgdpgqgC<-* y ++qgC KIAA1857 465 Y------WRQGC 470 PF00008.17.fs: domain 3 of 3, from 475 to 505: score 25.8, E = 2.6e-06 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C+++ C+ngGtC++ + +C Cp G ytG rC KIAA1857 475 CDDDQLLCQNGGTCLQNQ---RCACPRG----YTGVRC 505 PF07974.3.ls: domain 2 of 2, from 475 to 505: score 25.3, E = 0.0002 *->C......CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-* C++++ C++ +GtC + +C C++g y+G C KIAA1857 475 CdddqllCQN-GGTCLQN-------QRCACPRG----YTGVRC 505 PF00008.17.ls: domain 3 of 3, from 475 to 505: score 27.6, E = 4.2e-05 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C+++ C+ngGtC++ + +C Cp G ytG rC KIAA1857 475 CDDDQLLCQNGGTCLQNQ---RCACPRG----YTGVRC 505 //