# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/bm03548.fasta.nr -Q ../query/KIAA1848.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA1848, 445 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7825155 sequences
Expectation_n fit: rho(ln(x))= 5.6233+/-0.000188; mu= 9.8574+/- 0.011
mean_var=86.9660+/-16.863, 0's: 47 Z-trim: 53 B-trim: 267 in 1/66
Lambda= 0.137531
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 37, opt: 25, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|55961144|emb|CAI12365.1| SH3-domain GRB2-like e ( 404) 2611 527.7 2e-147
gi|220830517|emb|CAX15002.1| SH3-domain GRB2-like ( 400) 2558 517.2 2.9e-144
gi|123857190|emb|CAM23165.1| SH3-domain GRB2-like ( 404) 2547 515.0 1.3e-143
gi|160185603|sp|Q5PPJ9.2|SHLB2_RAT RecName: Full=E ( 404) 2534 512.4 7.8e-143
gi|73967824|ref|XP_850321.1| PREDICTED: similar to ( 403) 2522 510.0 4.1e-142
gi|160409932|sp|Q8R3V5.2|SHLB2_MOUSE RecName: Full ( 400) 2494 504.5 1.9e-140
gi|73967834|ref|XP_861352.1| PREDICTED: similar to ( 399) 2469 499.5 5.9e-139
gi|73967826|ref|XP_861239.1| PREDICTED: similar to ( 398) 2466 498.9 8.9e-139
gi|126297700|ref|XP_001363849.1| PREDICTED: hypoth ( 399) 2142 434.6 2e-119
gi|82233766|sp|Q5ZJ81.1|SHLB2_CHICK RecName: Full= ( 403) 2107 427.7 2.5e-117
gi|51704140|gb|AAH81208.1| MGC84737 protein [Xenop ( 396) 2099 426.1 7.4e-117
gi|123232871|emb|CAM15469.1| SH3-domain GRB2-like ( 402) 1958 398.1 2e-108
gi|190344051|gb|ACE75827.1| endophilin-B2 (predict ( 328) 1948 396.1 6.7e-108
gi|123232872|emb|CAM15470.1| SH3-domain GRB2-like ( 397) 1926 391.8 1.6e-106
gi|56388788|gb|AAH87652.1| SH3-domain GRB2-like en ( 330) 1837 374.1 2.9e-101
gi|41018150|sp|Q9NR46.1|SHLB2_HUMAN RecName: Full= ( 395) 1812 369.2 1e-99
gi|169409555|gb|ACA57900.1| SH3-domain GRB2-like e ( 395) 1799 366.6 6.1e-99
gi|194033680|ref|XP_001928957.1| PREDICTED: simila ( 395) 1784 363.6 4.8e-98
gi|74214713|dbj|BAE31195.1| unnamed protein produc ( 395) 1783 363.4 5.5e-98
gi|19353958|gb|AAH24477.1| SH3-domain GRB2-like en ( 395) 1783 363.4 5.5e-98
gi|73967816|ref|XP_548427.2| PREDICTED: similar to ( 394) 1782 363.2 6.3e-98
gi|198285992|gb|ACH85555.1| SH3-domain GRB2-like e ( 395) 1782 363.2 6.4e-98
gi|16518438|gb|AAL24820.1|AF426314_1 SH3GLB2 [Mus ( 395) 1777 362.2 1.3e-97
gi|157273780|gb|ABV27537.1| stimulator of prostati ( 395) 1776 362.0 1.5e-97
gi|149039097|gb|EDL93317.1| SH3-domain GRB2-like e ( 395) 1765 359.8 6.6e-97
gi|122132288|sp|Q08DK5.1|SHLB2_BOVIN RecName: Full ( 395) 1764 359.6 7.6e-97
gi|194225912|ref|XP_001499835.2| PREDICTED: simila ( 392) 1650 337.0 4.8e-90
gi|50604172|gb|AAH77597.1| Sh3glb2-prov protein [X ( 392) 1622 331.5 2.3e-88
gi|58477100|gb|AAH89758.1| MGC108465 protein [Xeno ( 390) 1582 323.5 5.6e-86
gi|63102473|gb|AAH95582.1| Zgc:111880 [Danio rerio ( 381) 1501 307.4 3.8e-81
gi|118341491|gb|AAI27566.1| Zgc:158183 protein [Da ( 353) 1495 306.2 8.1e-81
gi|166183811|gb|ABY84172.1| SH3-domain GRB2-like e ( 298) 1336 274.6 2.2e-71
gi|148676512|gb|EDL08459.1| SH3-domain GRB2-like e ( 298) 1307 268.9 1.2e-69
gi|73967832|ref|XP_861324.1| PREDICTED: similar to ( 386) 1304 268.4 2.2e-69
gi|109009575|ref|XP_001109686.1| PREDICTED: SH3-co ( 394) 1304 268.4 2.3e-69
gi|149039101|gb|EDL93321.1| SH3-domain GRB2-like e ( 298) 1299 267.3 3.6e-69
gi|149039098|gb|EDL93318.1| SH3-domain GRB2-like e ( 201) 1198 247.1 2.9e-63
gi|119608265|gb|EAW87859.1| SH3-domain GRB2-like e ( 232) 1198 247.2 3.2e-63
gi|220830518|emb|CAX15003.1| SH3-domain GRB2-like ( 374) 1198 247.3 4.6e-63
gi|194211143|ref|XP_001495966.2| PREDICTED: simila ( 536) 1189 245.6 2.1e-62
gi|73967828|ref|XP_861267.1| PREDICTED: similar to ( 373) 1182 244.1 4.2e-62
gi|73967818|ref|XP_861123.1| PREDICTED: similar to ( 378) 1182 244.1 4.2e-62
gi|73967836|ref|XP_861378.1| PREDICTED: similar to ( 365) 1178 243.3 7.1e-62
gi|73967822|ref|XP_861180.1| PREDICTED: similar to ( 370) 1178 243.3 7.2e-62
gi|73967820|ref|XP_861150.1| PREDICTED: similar to ( 385) 1178 243.4 7.4e-62
gi|73967830|ref|XP_861299.1| PREDICTED: similar to ( 386) 1178 243.4 7.4e-62
gi|37362288|gb|AAQ91272.1| SH3-domain GRB2-like en ( 254) 1175 242.6 8.1e-62
gi|22137336|gb|AAH28859.1| Sh3glb2 protein [Mus mu ( 287) 1173 242.3 1.2e-61
gi|123857192|emb|CAM23167.1| SH3-domain GRB2-like ( 374) 1173 242.4 1.4e-61
gi|149039103|gb|EDL93323.1| SH3-domain GRB2-like e ( 209) 1169 241.4 1.6e-61
>>gi|55961144|emb|CAI12365.1| SH3-domain GRB2-like endop (404 aa)
initn: 2611 init1: 2611 opt: 2611 Z-score: 2803.1 bits: 527.7 E(): 2e-147
Smith-Waterman score: 2611; 100.000% identity (100.000% similar) in 404 aa overlap (42-445:1-404)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|559 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
160 170 180 190 200 210
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
220 230 240 250 260 270
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
280 290 300 310 320 330
380 390 400 410 420 430
KIAA18 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
340 350 360 370 380 390
440
KIAA18 KKGKVPVTYLELLS
::::::::::::::
gi|559 KKGKVPVTYLELLS
400
>>gi|220830517|emb|CAX15002.1| SH3-domain GRB2-like endo (400 aa)
initn: 1390 init1: 1390 opt: 2558 Z-score: 2746.3 bits: 517.2 E(): 2.9e-144
Smith-Waterman score: 2558; 99.010% identity (99.010% similar) in 404 aa overlap (42-445:1-400)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|220 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
gi|220 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKAT----TVPDFQETRPRNYILSASA
160 170 180 190 200
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
210 220 230 240 250 260
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
270 280 290 300 310 320
380 390 400 410 420 430
KIAA18 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
330 340 350 360 370 380
440
KIAA18 KKGKVPVTYLELLS
::::::::::::::
gi|220 KKGKVPVTYLELLS
390 400
>>gi|123857190|emb|CAM23165.1| SH3-domain GRB2-like endo (404 aa)
initn: 2547 init1: 2547 opt: 2547 Z-score: 2734.4 bits: 515.0 E(): 1.3e-143
Smith-Waterman score: 2547; 97.030% identity (99.257% similar) in 404 aa overlap (42-445:1-404)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|123 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
gi|123 EKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
:::::::::.:::::::.::::::::::.::::.:::::::::::::.::::::::::::
gi|123 GELLAQYMAEAASELGPSTPYGKTLIKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|123 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
160 170 180 190 200 210
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|123 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
220 230 240 250 260 270
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
::::::::::::::::::::::::::::::::::::::::::.::::::::. : ::::
gi|123 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAVLAPPE
280 290 300 310 320 330
380 390 400 410 420 430
KIAA18 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|123 EAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
340 350 360 370 380 390
440
KIAA18 KKGKVPVTYLELLS
::::::::::::::
gi|123 KKGKVPVTYLELLS
400
>>gi|160185603|sp|Q5PPJ9.2|SHLB2_RAT RecName: Full=Endop (404 aa)
initn: 2534 init1: 2534 opt: 2534 Z-score: 2720.5 bits: 512.4 E(): 7.8e-143
Smith-Waterman score: 2534; 96.287% identity (99.505% similar) in 404 aa overlap (42-445:1-404)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|160 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
gi|160 EKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
:::::::::.:::::::.:::::::.::.::::.:::::::::::::.::::::::::::
gi|160 GELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|160 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
160 170 180 190 200 210
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
::::::::::::::::.:::::::::::::::::::::.:::::::::::::::::::::
gi|160 SALWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQ
220 230 240 250 260 270
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
::::::::::::::::::::::::::::::::::::::::::.::::::::. :.::::
gi|160 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPE
280 290 300 310 320 330
380 390 400 410 420 430
KIAA18 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|160 EAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
340 350 360 370 380 390
440
KIAA18 KKGKVPVTYLELLS
::::::::::::::
gi|160 KKGKVPVTYLELLS
400
>>gi|73967824|ref|XP_850321.1| PREDICTED: similar to SH3 (403 aa)
initn: 2147 init1: 2119 opt: 2522 Z-score: 2707.7 bits: 510.0 E(): 4.1e-142
Smith-Waterman score: 2522; 97.030% identity (99.257% similar) in 404 aa overlap (42-445:1-403)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|739 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
:::::::::.:::::::::::::::::::::::.::::::::::::::.:::::::::::
gi|739 GELLAQYMAEAASELGPTTPYGKTLIKVAEAEKRLGAAERDFIHTASINFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
160 170 180 190 200 210
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
gi|739 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVESQTTYYAQ
220 230 240 250 260 270
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
::::::::::::::::::::::::::::::.::::::::::::.::::: ::::.:::::
gi|739 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPVSPPLSSTSPTTAVATMPVGPSVAGLAPPG
280 290 300 310 320 330
380 390 400 410 420 430
KIAA18 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
::.: :: :.::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 EAALRLE-VTPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
340 350 360 370 380
440
KIAA18 KKGKVPVTYLELLS
::::::::::::::
gi|739 KKGKVPVTYLELLS
390 400
>>gi|160409932|sp|Q8R3V5.2|SHLB2_MOUSE RecName: Full=End (400 aa)
initn: 1351 init1: 1351 opt: 2494 Z-score: 2677.7 bits: 504.5 E(): 1.9e-140
Smith-Waterman score: 2494; 96.040% identity (98.267% similar) in 404 aa overlap (42-445:1-400)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|160 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
gi|160 EKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
:::::::::.:::::::.::::::::::.::::.:::::::::::::.::::::::::::
gi|160 GELLAQYMAEAASELGPSTPYGKTLIKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
gi|160 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKAT----TVPDFQETRPRNYILSASA
160 170 180 190 200
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|160 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
210 220 230 240 250 260
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
::::::::::::::::::::::::::::::::::::::::::.::::::::. : ::::
gi|160 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAVLAPPE
270 280 290 300 310 320
380 390 400 410 420 430
KIAA18 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|160 EAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
330 340 350 360 370 380
440
KIAA18 KKGKVPVTYLELLS
::::::::::::::
gi|160 KKGKVPVTYLELLS
390 400
>>gi|73967834|ref|XP_861352.1| PREDICTED: similar to SH3 (399 aa)
initn: 2072 init1: 1175 opt: 2469 Z-score: 2650.9 bits: 499.5 E(): 5.9e-139
Smith-Waterman score: 2469; 96.040% identity (98.267% similar) in 404 aa overlap (42-445:1-399)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|739 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
:::::::::.:::::::::::::::::::::::.::::::::::::::.:::::::::::
gi|739 GELLAQYMAEAASELGPTTPYGKTLIKVAEAEKRLGAAERDFIHTASINFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
gi|739 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKAT----TVPDFQETRPRNYILSASA
160 170 180 190 200
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
gi|739 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVESQTTYYAQ
210 220 230 240 250 260
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
::::::::::::::::::::::::::::::.::::::::::::.::::: ::::.:::::
gi|739 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPVSPPLSSTSPTTAVATMPVGPSVAGLAPPG
270 280 290 300 310 320
380 390 400 410 420 430
KIAA18 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
::.: :: :.::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 EAALRLE-VTPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
330 340 350 360 370 380
440
KIAA18 KKGKVPVTYLELLS
::::::::::::::
gi|739 KKGKVPVTYLELLS
390
>>gi|73967826|ref|XP_861239.1| PREDICTED: similar to SH3 (398 aa)
initn: 2223 init1: 1810 opt: 2466 Z-score: 2647.7 bits: 498.9 E(): 8.9e-139
Smith-Waterman score: 2466; 95.545% identity (97.772% similar) in 404 aa overlap (42-445:1-398)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|739 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
:::::::::.:::::::::::::::::::::::.::::::::::::::.:::::::::::
gi|739 GELLAQYMAEAASELGPTTPYGKTLIKVAEAEKRLGAAERDFIHTASINFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
160 170 180 190 200 210
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
gi|739 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVESQTTYYAQ
220 230 240 250 260 270
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPG
::::::::::::: :::::::::::.::::::::::::.::::: ::::.:::::
gi|739 CYRHMLDLQKQLGR-----FPGTFVGTTEPVSPPLSSTSPTTAVATMPVGPSVAGLAPPG
280 290 300 310 320
380 390 400 410 420 430
KIAA18 EASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
::.: :: :.::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 EAALRLE-VTPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGN
330 340 350 360 370 380
440
KIAA18 KKGKVPVTYLELLS
::::::::::::::
gi|739 KKGKVPVTYLELLS
390
>>gi|126297700|ref|XP_001363849.1| PREDICTED: hypothetic (399 aa)
initn: 1747 init1: 1132 opt: 2142 Z-score: 2300.2 bits: 434.6 E(): 2e-119
Smith-Waterman score: 2142; 84.198% identity (93.580% similar) in 405 aa overlap (42-445:1-399)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::::::::::::::::::::::::::::
gi|126 MDFNMKKLASDAGIFFTRAVQFTEEKFGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|126 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
::::::::..::.:::: ::::::::::.:.:: ::::::::::.:::.:::::::::::
gi|126 GELLAQYMTEAANELGPETPYGKTLIKVGETEKCLGAAERDFIHSASINFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::.:::::::.:::::::::::::::::::::::::. .::::::::::::::::::
gi|126 DWRTISKERRILQNRRLDLDACKARLKKAKAAEAKAA----AVPDFQETRPRNYILSASA
160 170 180 190 200
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
::::.::::::::::::::::::::::::::::::::::::..: : . :.. . : .
gi|126 SALWSDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVSYLLCARFFINISITLASV
210 220 230 240 250 260
320 330 340 350 360 370
KIAA18 CYRHMLDLQKQLG-SSQGAIFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPP
: :. :.: ..:: ..: . :::::::.::::: ::::.: .:::::.::::.::..
gi|126 CIRK-LEL-RSLGLQGQLSKFPGTFVGNTEPASSPLSSASLATAAATIPVVPTVAGIPAT
270 280 290 300 310 320
380 390 400 410 420 430
KIAA18 GEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERG
:::.. :..:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|126 GEAAISLDDVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERG
330 340 350 360 370 380
440
KIAA18 NKKGKVPVTYLELLS
:.:::::::::::::
gi|126 NRKGKVPVTYLELLS
390
>>gi|82233766|sp|Q5ZJ81.1|SHLB2_CHICK RecName: Full=Endo (403 aa)
initn: 1646 init1: 1099 opt: 2107 Z-score: 2262.6 bits: 427.7 E(): 2.5e-117
Smith-Waterman score: 2126; 80.340% identity (92.718% similar) in 412 aa overlap (42-445:1-403)
20 30 40 50 60 70
KIAA18 AGGRGAVGGGGWAGGCRLRSGRARRPCGHAMDFNMKKLASDAGIFFTRAVQFTEEKFGQA
::::.::::::::.::.::.::::::.:::
gi|822 MDFNVKKLASDAGVFFSRAMQFTEEKLGQA
10 20 30
80 90 100 110 120 130
KIAA18 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|822 EKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTN
40 50 60 70 80 90
140 150 160 170 180 190
KIAA18 GELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEG
::::::::..::...:: ::::::::::.:....::::::::::.:::.:::::::::::
gi|822 GELLAQYMTEAANDFGPGTPYGKTLIKVGETQRRLGAAERDFIHSASINFLTPLRNFLEG
100 110 120 130 140 150
200 210 220 230 240 250
KIAA18 DWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASA
::.:::::::.:::::::::::::::::::::::::. .::::::::::::.:::::
gi|822 DWRTISKERRILQNRRLDLDACKARLKKAKAAEAKAA----AVPDFQETRPRNYVLSASA
160 170 180 190 200
260 270 280 290 300 310
KIAA18 SALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQ
::::.:::.:::.:::..:::::::::::::::::::::::::::::::::.:::.::::
gi|822 SALWSDEVEKAEHELRLTQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVESQTNYYAQ
210 220 230 240 250 260
320 330 340 350 360
KIAA18 CYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTAAAT-------MPVVPSV
::..::::::::: : :::::..: .::: ...:: ..::: .::::..
gi|822 CYQYMLDLQKQLGR-----FSGTFVGNAESTSPPPAAASPPAVAATTLPAVPTIPVVPTI
270 280 290 300 310 320
370 380 390 400 410 420
KIAA18 ASLAPP-GEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPD
... .:. : .:: ::::::::::::::::::::.::::::::.::::::::::::
gi|822 VGVPNTVAESVLNPNEVKPPASGTRKARVLYDYEAADSTELALLADEMITVYSLPGMDPD
330 340 350 360 370 380
430 440
KIAA18 WLIGERGNKKGKVPVTYLELLS
::::::::.:::::::::::::
gi|822 WLIGERGNQKGKVPVTYLELLS
390 400
445 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Thu Mar 5 22:34:46 2009 done: Thu Mar 5 22:39:04 2009
Total Scan time: 1478.980 Total Display time: 0.140
Function used was FASTA [version 34.26.5 April 26, 2007]