# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/hj01608.fasta.huge -Q ../query/KIAA1830.ptfa ./tmplib.25089 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1830, 486 aa
 vs ./tmplib.25089 library

1987019 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 4.3890+/-0.00454; mu= 15.7059+/- 0.309
 mean_var=74.1616+/-17.564, 0's: 0 Z-trim: 2  B-trim: 9 in 1/39
 Lambda= 0.148931

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 37, opt: 25, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA0573  ( 451 res)   hj00186                     ( 451)  178 47.7   2e-06
KIAA0962  ( 822 res)   hj05850s1                   ( 822)  159 43.9   5e-05


>>KIAA0573  ( 451 res)   hj00186                          (451 aa)
 initn: 137 init1:  97 opt: 178  Z-score: 207.3  bits: 47.7 E(): 2e-06
Smith-Waterman score: 200;  20.725% identity (54.663% similar) in 386 aa overlap (3-374:34-399)

                                           10         20        30 
KIAA18                             SAPFPFPGGQAADPSVFI-PLLHSQLLQLSRA
                                     : : :   ..:::: . : .  .: .: : 
KIAA05 GAAAWRILRCRRLPEPSPFLTQPNLAQSQPPAPVP---VTDPSVTMHPAVFLSLPDL-RC
            10        20        30           40        50          

              40        50        60        70        80        90 
KIAA18 SMAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKL
       :.    .:.   . . .. ::       .:..:: ..   : :. ::.::: ::   . :
KIAA05 SLLLLVTWVFTPVTTEITSLD-------TENIDEILN---NADVALVNFYADWCRFSQML
      60        70        80                  90       100         

             100          110       120       130       140        
KIAA18 EPIWNEVGLEMKS---IGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYN--YR
       .::..:..  .:      . :  ...:  ..:.::... .  :::.::... . ..  ::
KIAA05 HPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYR
     110       120       130       140       150       160         

        150       160       170       180       190       200      
KIAA18 GPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASEL
       : :.   . .. .. ..  :. . .   .  ... .: .. :   ..  . . .. ....
KIAA05 GQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFERVANI
     170       180       190       200       210       220         

        210        220        230       240       250        260   
KIAA18 IVYT-YFFSASEEVV-PEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSW-INRERFQNY
       .     :.::  .:  ::  .  ..    ..:   . . :    : .... .. . .:. 
KIAA05 LHDDCAFLSAFGDVSKPERYSGDNI----IYKPPGHSAPDMVYLGAMTNFDVTYNWIQDK
     230       240       250           260       270       280     

            270       280       290       300       310       320  
KIAA18 -LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHM
        . .   . .: :.     .:  .   . . .   :. . .::::.  .  .  ..: : 
KIAA05 CVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISE-KGTINFLHA
         290       300       310       320       330        340    

            330       340          350        360       370        
KIAA18 DGNDYINTLLMDELTVPT---VVVLNTSNQQYFLLD-RQIKNVEDMVQFINNILDGTVEA
       : . . . ::  . : :.   :.....  ..: . : ...     . ::. .. .:    
KIAA05 DCDKFRHPLLHIQKT-PADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHR
          350        360       370       380       390       400   

      380       390       400       410       420       430        
KIAA18 QGGDSILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYI
                                                                   
KIAA05 EFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL            
           410       420       430       440       450             

>>KIAA0962  ( 822 res)   hj05850s1                        (822 aa)
 initn: 116 init1:  89 opt: 159  Z-score: 182.2  bits: 43.9 E(): 5e-05
Smith-Waterman score: 159;  22.222% identity (58.201% similar) in 189 aa overlap (61-237:192-371)

               40        50        60        70        80        90
KIAA18 ASMAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKK
                                     : . .:::.      .:. . . ::  : .
KIAA09 DESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKP-----YLIKITSDWCFSCIH
             170       180       190       200            210      

              100       110       120       130        140         
KIAA18 LEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTI-KLLKGDLAYNYRGPR
       .::.:.::  :.. .:  : .: . :     .: ..:... :.:  ...: ... ...  
KIAA09 IEPVWKEVIQELEELG--VGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISF-FHNAV
        220       230         240       250       260        270   

     150       160        170             180       190       200  
KIAA18 TKDDIIEFAHRV-SGALIRPLPSQQM------FEHMQKRHRVFFVYVGGESPLKEKYID-
       ..... .:.. .  : :.. . ....      ... .: : ..:  .    ::  :    
KIAA09 VRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQTPI-VPLLYKLTAF
           280       290       300       310       320        330  

             210          220       230       240       250        
KIAA18 AASELIVYTYFF---SASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRE
       : .. . . : .    ..::.. .:      :..::::.                     
KIAA09 AYKDYLSFGYVYVGLRGTEEMTRRYNINIYAPTLLVFKEHINRPADVIQARGMKKQIIDD
            340       350       360       370       380       390  

      260       270       280       290       300       310        
KIAA18 RFQNYLAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQ
                                                                   
KIAA09 FITRNKYLLAARLTSQKLFHELCPVKRSHRQRKYCVVLLTAETTKLSKPFEAFLSFALAN
            400       410       420       430       440       450  




486 residues in 1 query   sequences
1987019 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:18:40 2008 done: Thu Dec 18 15:18:41 2008
 Total Scan time:  0.440 Total Display time:  0.020

Function used was FASTA [version 34.26.5 April 26, 2007]