# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/fh12913.fasta.huge -Q ../query/KIAA1821.ptfa ./tmplib.25089 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1821, 609 aa
 vs ./tmplib.25089 library

1986896 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 10.2448+/-0.00948; mu= -11.6612+/- 0.638
 mean_var=393.3653+/-97.055, 0's: 0 Z-trim: 8  B-trim: 80 in 1/39
 Lambda= 0.064666

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA0665  ( 760 res)   hk02064                     ( 760) 1095 116.6 7.7e-27


>>KIAA0665  ( 760 res)   hk02064                          (760 aa)
 initn: 1305 init1: 619 opt: 1095  Z-score: 573.7  bits: 116.6 E(): 7.7e-27
Smith-Waterman score: 1270;  39.836% identity (67.377% similar) in 610 aa overlap (3-608:221-760)

                                           10        20        30  
KIAA18                             GRDPDGFLRVERVAALGLRFGQGEEVEKLVKY
                                     : :::.:.:    ..  .: .:.:. :.::
KIAA06 LSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYG-AEQVKDLTKY
              200       210       220       230        240         

             40        50           60        70        80         
KIAA18 LDPNDLGRINFKDFCRGVFAMKGCE---ELLKDVLSVESAGTLPCAPEIPDCVE-QGSEV
       :::. :: :.:.:: .:. :... .   .    : :...   : :  :. : :  ...::
KIAA06 LDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTYEANEV
     250       260       270       280       290       300         

       90       100       110       120       130       140        
KIAA18 TGPTFADGELIPREPGFFPEDEEEAMTLAPPEGPQELYTDSPMESTQSLEGSVGSPAEKD
       :  ..  .:    :   : .  :.. ::. ::   :  .::         :. . :.:  
KIAA06 TDSAYMGSESTYSECETFTD--EDTSTLVHPELQPEGDADSA--------GGSAVPSEC-
     310       320         330       340               350         

      150       160       170       180       190       200        
KIAA18 GGLGGLFLPEDKSLVHTPSMTTSDLSTHSTTSLISNEEQFEDYGEGDDVDCAPSSPCPDD
         : ..  :.  .:.  :.        .:. ..:..::.:::::::.... .: . :   
KIAA06 --LDAMEEPDHGALLLLPGRPHPH--GQSVITVIGGEEHFEDYGEGSEAELSPETLCN--
        360       370       380         390       400       410    

      210       220       230       240       250       260        
KIAA18 ETRTNVYSDLGSSVSSSAGQTPRKMRHVYNSELLDVYCSQCCKKINLLNDLEARLKNLKA
              ..::   :. :  ::                                      
KIAA06 -------GQLGC--SDPAFLTP--------------------------------------
                     420                                           

      270       280       290       300       310       320        
KIAA18 NSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELEN
        ::....::   .: : .:. ..    . ::   . ... ..::..:: :::..: :::.
KIAA06 -SPTKRLSSKKVARYLHQSGALTME--ALEDPSPELMEGPEEDIADKVVFLERRVLELEK
          430       440         450       460       470       480  

      330       340       350       360       370       380        
KIAA18 DSLTNGDLKSKLKQENTQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKA
       :. ..:. .:.:.::: :::::.. :::..:.::  : . . ::.::..:   :.::::.
KIAA06 DTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKS
            490       500       510       520       530       540  

      390       400       410       420       430       440        
KIAA18 TEVELLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDLYK
        :.: :..:.:::.:::.:::. .  ::.. :.:.::.:.. :..:. .:::..:..  .
KIAA06 IEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKR
            550       560       570       580       590       600  

      450       460       470       480       490       500        
KIAA18 RMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNAR
       :: :.: ..: .::...::::::::::::.:::::. ::. :.  ::::.: :: :...:
KIAA06 RMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQR-RGRSSSMGLQEYHSR
            610       620       630       640        650       660 

      510       520       530       540       550       560        
KIAA18 AREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEIDTAS
       ::: :::.::.::::.: .:..::..:::::..::.  ::.::..   ..::::::...:
KIAA06 ARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAF-SESLAAEISSVS
             670       680       690       700        710       720

      570       580       590       600         
KIAA18 RDELMEALKEQEEINFRLRQYMDKIILAILDHNPSILEIKH
       :::::::...::::::::..:.:.::.::.. ::::::.: 
KIAA06 RDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK 
              730       740       750       760 




609 residues in 1 query   sequences
1986896 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:18:20 2008 done: Thu Dec 18 15:18:21 2008
 Total Scan time:  0.510 Total Display time:  0.030

Function used was FASTA [version 34.26.5 April 26, 2007]