hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080909/iprscan-20080909-09473277/chunk_1/iprscan-20080909-09473277.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1763 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF02210.14.ls Laminin G domain 429.8 3.4e-126 4 PF02210.14.fs Laminin G domain 422.4 5.7e-124 4 PF00054.13.fs Laminin G domain 149.0 2e-42 4 PF00054.13.ls Laminin G domain 149.5 8.1e-42 4 PF00754.15.ls F5/8 type C domain 140.9 3.3e-39 1 PF00754.15.fs F5/8 type C domain 139.0 5.9e-39 1 PF00008.17.fs EGF-like domain 48.7 9.3e-13 2 PF00008.17.ls EGF-like domain 52.5 1.3e-12 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00754.15.ls 1/1 57 188 .. 1 163 [] 140.9 3.3e-39 PF00754.15.fs 1/1 57 188 .. 1 163 [] 139.0 5.9e-39 PF02210.14.fs 1/4 226 355 .. 1 141 [] 114.8 3.8e-33 PF02210.14.ls 1/4 226 355 .. 1 141 [] 116.6 6.5e-32 PF00054.13.fs 2/4 412 541 .. 1 159 [] 57.9 2.9e-16 PF02210.14.fs 2/4 412 538 .. 1 141 [] 103.0 1e-29 PF00054.13.ls 2/4 412 541 .. 1 159 [] 59.7 8.6e-15 PF02210.14.ls 2/4 412 538 .. 1 141 [] 104.9 2.2e-28 PF00008.17.fs 1/2 567 599 .. 1 38 [] 28.5 4.4e-07 PF00008.17.ls 1/2 567 599 .. 1 38 [] 30.4 6e-06 PF02210.14.fs 3/4 835 954 .. 1 141 [] 125.1 3.7e-36 PF00054.13.ls 3/4 835 957 .. 1 159 [] 68.9 1.5e-17 PF00054.13.fs 3/4 835 957 .. 1 159 [] 67.1 6.6e-19 PF02210.14.ls 3/4 835 954 .. 1 141 [] 126.9 5.3e-35 PF00008.17.ls 2/2 976 1010 .. 1 38 [] 22.1 0.0019 PF02210.14.fs 4/4 1060 1190 .. 1 141 [] 79.5 7.4e-23 PF02210.14.ls 4/4 1060 1190 .. 1 141 [] 81.4 2.6e-21 Alignments of top-scoring domains: PF00754.15.ls: domain 1 of 1, from 57 to 188: score 140.9, E = 3.3e-39 *->qitaSseesgsggagrarLwspaaaalDGngntyghsvspstaWsse + ++Sse s+s+g+g+arL+ DG ++Ws+ KIAA1763 57 SFSSSSELSSSHGPGFARLNRR-----DGA-----------GGWSP- 86 kwsggaknndapqwlqvDLgkpkkitgvvtqgrqdggngyvksYkiqySd +++ qwlq+DLg+ +++t+v tqg++++ n +v+sY ++ Sd KIAA1763 87 LV------SNKYQWLQIDLGERMEVTAVATQGGYGSSN-WVTSYLLMFSD 129 DGseevnWttvkdgedilsdsgg.pkiF.gn.dnd.pvknlfdppikARY G nW+++++ ++ + F+gn ++d++v+ + p+ikAR+ KIAA1763 130 SG-W--NWKQYRQ--------EDsIWGFsGNaNADsVVYYRLQPSIKARF 168 vRivptswnggggiasraEl<-* +R++p++wn+ g+i++r E+ KIAA1763 169 LRFIPLEWNPKGRIGMRIEV 188 PF00754.15.fs: domain 1 of 1, from 57 to 188: score 139.0, E = 5.9e-39 *->qitaSseesgsggagrarLwspaaaalDGngntyghsvspstaWsse + ++Sse s+s+g+g+arL+ DG ++Ws+ KIAA1763 57 SFSSSSELSSSHGPGFARLNRR-----DGA-----------GGWSP- 86 kwsggaknndapqwlqvDLgkpkkitgvvtqgrqdggngyvksYkiqySd +++ qwlq+DLg+ +++t+v tqg++++ n +v+sY ++ Sd KIAA1763 87 LV------SNKYQWLQIDLGERMEVTAVATQGGYGSSN-WVTSYLLMFSD 129 DGseevnWttvkdgedilsdsgg.pkiF.gn.dnd.pvknlfdppikARY G nW+++++ ++ + F+gn ++d++v+ + p+ikAR+ KIAA1763 130 SG-W--NWKQYRQ--------EDsIWGFsGNaNADsVVYYRLQPSIKARF 168 vRivptswnggggiasraEl<-* +R++p++wn+ g+i++r E+ KIAA1763 169 LRFIPLEWNPKGRIGMRIEV 188 PF02210.14.fs: domain 1 of 4, from 226 to 355: score 114.8, E = 3.8e-33 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLvdGrlvlrydl F+T q++G+Ll+ +g +g d +++L+L+ rl l ++ KIAA1763 226 FKT-MQSDGILLHREGPnG---------D-HITLQLRRARLFLLINS 261 G......sgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g. G+ + +++++ v lt g+ l+D +WH+V + r g++v ++VD ++++ KIAA1763 262 GeaklpsTSTlVNLTLGsLLDDQHWHSVLIQRLGKQVNFTVDEHrHHfHa 311 spgssdtlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCir +++ +nl++++ +GG+p +ks + + ++F+GC++ KIAA1763 312 RGEFN---LMNLDYEISFGGIPAPGKSVSFP----------HrNFHGCLE 348 nvringe<-* n+++ng+ KIAA1763 349 NLYYNGV 355 PF02210.14.ls: domain 1 of 4, from 226 to 355: score 116.6, E = 6.5e-32 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLvdGrlvlrydl F+T q++G+Ll+ +g +g d +++L+L+ rl l ++ KIAA1763 226 FKT-MQSDGILLHREGPnG---------D-HITLQLRRARLFLLINS 261 G......sgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g. G+ + +++++ v lt g+ l+D +WH+V + r g++v ++VD ++++ KIAA1763 262 GeaklpsTSTlVNLTLGsLLDDQHWHSVLIQRLGKQVNFTVDEHrHHfHa 311 spgssdtlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCir +++ +nl++++ +GG+p +ks + + ++F+GC++ KIAA1763 312 RGEFN---LMNLDYEISFGGIPAPGKSVSFP----------HrNFHGCLE 348 nvringe<-* n+++ng+ KIAA1763 349 NLYYNGV 355 PF00054.13.fs: domain 2 of 4, from 412 to 541: score 57.9, E = 2.9e-16 *->FRTtepsGlLllgYnGtqterrskkeigdDFlaleLvdGrlev.syd FRT++ GlLl + q ++ ++l L dG+l+ + y+ KIAA1763 412 FRTWNKAGLLL--FSELQLISGG--------ILLFLSDGKLKSnLYQ 448 lGsgrlrpavvrsgdkvlnDGkWHsvelerngrsgtLsVdgearskktLg G+ p +++g++ lnDG+WHsv+l+ + ++++ Vdg + KIAA1763 449 PGKL---PSDITAGVE-LNDGQWHSVSLSAKKNHLSVAVDGQMA------ 488 GsvvtgesplgattesttLdvdgkLyvGGlPeldqavkarrlaispsfkG + + lg+++ + g y+GG P d+++ +++ + +f G KIAA1763 489 ----SAAPLLGPEQ----IYSGGTYYFGGCP--DKSFGSKCKSPLGGFQG 528 Cirdviingkpld<-* C+r ++i+gk +d KIAA1763 529 CMRLISISGKVVD 541 PF02210.14.fs: domain 2 of 4, from 412 to 538: score 103.0, E = 1e-29 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLvdGrlvlrydl FRT + + GlLl+++ + s+ + L+L dG+l+ + KIAA1763 412 FRT-WNKAGLLLFSELQlI--------SG-GILLFLSDGKLKSNLYQ 448 Gsgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g.spgssd ++ ++ +t g lnDGqWH+Vs++ +++++++ VDg+ ++ +++ g++ KIAA1763 449 PGKLpSDITAGvELNDGQWHSVSLSAKKNHLSVAVDGQmASaApLLGPE- 497 tlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCirnvring + g +y+GG+p+ s s+++++ +gF+GC+r + i g KIAA1763 498 --QIYSGGTYYFGGCPDKSFGSKCKSP--------LgGFQGCMRLISISG 537 e<-* + KIAA1763 538 K 538 PF00054.13.ls: domain 2 of 4, from 412 to 541: score 59.7, E = 8.6e-15 *->FRTtepsGlLllgYnGtqterrskkeigdDFlaleLvdGrlev.syd FRT++ GlLl + q ++ ++l L dG+l+ + y+ KIAA1763 412 FRTWNKAGLLL--FSELQLISGG--------ILLFLSDGKLKSnLYQ 448 lGsgrlrpavvrsgdkvlnDGkWHsvelerngrsgtLsVdgearskktLg G+ p +++g++ lnDG+WHsv+l+ + ++++ Vdg + KIAA1763 449 PGKL---PSDITAGVE-LNDGQWHSVSLSAKKNHLSVAVDGQMA------ 488 GsvvtgesplgattesttLdvdgkLyvGGlPeldqavkarrlaispsfkG + + lg+++ + g y+GG P d+++ +++ + +f G KIAA1763 489 ----SAAPLLGPEQ----IYSGGTYYFGGCP--DKSFGSKCKSPLGGFQG 528 Cirdviingkpld<-* C+r ++i+gk +d KIAA1763 529 CMRLISISGKVVD 541 PF02210.14.ls: domain 2 of 4, from 412 to 538: score 104.9, E = 2.2e-28 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLvdGrlvlrydl FRT + + GlLl+++ + s+ + L+L dG+l+ + KIAA1763 412 FRT-WNKAGLLLFSELQlI--------SG-GILLFLSDGKLKSNLYQ 448 Gsgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g.spgssd ++ ++ +t g lnDGqWH+Vs++ +++++++ VDg+ ++ +++ g++ KIAA1763 449 PGKLpSDITAGvELNDGQWHSVSLSAKKNHLSVAVDGQmASaApLLGPE- 497 tlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCirnvring + g +y+GG+p+ s s+++++ +gF+GC+r + i g KIAA1763 498 --QIYSGGTYYFGGCPDKSFGSKCKSP--------LgGFQGCMRLISISG 537 e<-* + KIAA1763 538 K 538 PF00008.17.fs: domain 1 of 2, from 567 to 599: score 28.5, E = 4.4e-07 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C pn +C +gG+C +++++++C C+ +y G +C KIAA1763 567 CLPN--YCEHGGECSQSWSTFHCNCTNT---GYRGATC 599 PF00008.17.ls: domain 1 of 2, from 567 to 599: score 30.4, E = 6e-06 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C pn +C +gG+C +++++++C C+ +y G +C KIAA1763 567 CLPN--YCEHGGECSQSWSTFHCNCTNT---GYRGATC 599 PF02210.14.fs: domain 3 of 4, from 835 to 954: score 125.1, E = 3.7e-36 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLvdGr.lvlryd F+T t+++G+ l + g+ + f+ +eL+ + + +++d KIAA1763 835 FKT-TASSGVFLENLGIaD-----------FIRIELRSPTvVTFSFD 869 lG.sgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g.spgs G+++ ++++ s++++nD+qWH+V+vern ++++L+VD+ ++ ++++p + KIAA1763 870 VGnGPFeISVQSPtHFNDNQWHHVRVERNMKEASLQVDQLtPKtQpAPAD 919 sdtlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCirnvri + l+ln++l++GG ++gF GCir++++ KIAA1763 920 GHV-LLQLNSQLFVGGTATR-----------------QrGFLGCIRSLQL 951 nge<-* ng KIAA1763 952 NGM 954 PF00054.13.ls: domain 3 of 4, from 835 to 957: score 68.9, E = 1.5e-17 *->FRTtepsGlLllgYnGtqterrskkeigdDFlaleLvdGr.levsyd F+Tt++sG+ l ++ +++ DF+ +eL+ + +s+d KIAA1763 835 FKTTASSGVFL-----ENLGIA-------DFIRIELRSPTvVTFSFD 869 lGsgrlr.pavvrsgdkvlnDGkWHsvelerngrsgtLsVdgearskktL +G+g + +++v s++ +nD++WH+v +ern ++++L+Vd + KIAA1763 870 VGNG--PfEISVQSPTH-FNDNQWHHVRVERNMKEASLQVDQLTP----- 911 gGsvvtgesplgattesttLdvdgkLyvGGlPeldqavkarrlaispsfk ++p +a++ + L ++ +L+vGG + +++f KIAA1763 912 ------KTQPAPADG-HVLLQLNSQLFVGGTA-----------TRQRGFL 943 GCirdviingkpld<-* GCir++ +ng+ ld KIAA1763 944 GCIRSLQLNGMTLD 957 PF00054.13.fs: domain 3 of 4, from 835 to 957: score 67.1, E = 6.6e-19 *->FRTtepsGlLllgYnGtqterrskkeigdDFlaleLvdGr.levsyd F+Tt++sG+ l ++ +++ DF+ +eL+ + +s+d KIAA1763 835 FKTTASSGVFL-----ENLGIA-------DFIRIELRSPTvVTFSFD 869 lGsgrlr.pavvrsgdkvlnDGkWHsvelerngrsgtLsVdgearskktL +G+g + +++v s++ +nD++WH+v +ern ++++L+Vd + KIAA1763 870 VGNG--PfEISVQSPTH-FNDNQWHHVRVERNMKEASLQVDQLTP----- 911 gGsvvtgesplgattesttLdvdgkLyvGGlPeldqavkarrlaispsfk ++p +a++ + L ++ +L+vGG + +++f KIAA1763 912 ------KTQPAPADG-HVLLQLNSQLFVGGTA-----------TRQRGFL 943 GCirdviingkpld<-* GCir++ +ng+ ld KIAA1763 944 GCIRSLQLNGMTLD 957 PF02210.14.ls: domain 3 of 4, from 835 to 954: score 126.9, E = 5.3e-35 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLvdGr.lvlryd F+T t+++G+ l + g+ + f+ +eL+ + + +++d KIAA1763 835 FKT-TASSGVFLENLGIaD-----------FIRIELRSPTvVTFSFD 869 lG.sgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g.spgs G+++ ++++ s++++nD+qWH+V+vern ++++L+VD+ ++ ++++p + KIAA1763 870 VGnGPFeISVQSPtHFNDNQWHHVRVERNMKEASLQVDQLtPKtQpAPAD 919 sdtlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCirnvri + l+ln++l++GG ++gF GCir++++ KIAA1763 920 GHV-LLQLNSQLFVGGTATR-----------------QrGFLGCIRSLQL 951 nge<-* ng KIAA1763 952 NGM 954 PF00008.17.ls: domain 2 of 2, from 976 to 1010: score 22.1, E = 0.0019 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* Cs+ C ngG+C++ p g++C+C+ +ytG++C KIAA1763 976 CSSYGKLCRNGGKCRERPIGFFCDCTFS---AYTGPFC 1010 PF02210.14.fs: domain 4 of 4, from 1060 to 1190: score 79.5, E = 7.4e-23 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLv.dGrlvlryd FRT t+ lLl++++ + +l++ + ++G l++ry+ KIAA1763 1060 FRT-TRTPSLLLFVSSFyK---------E-YLSVIIAkNGSLQIRYK 1095 lG..sgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g.spg l++ +++v+ ++ ++++DGq H++ + r+++ v +++D+ + ++++++ KIAA1763 1096 LNkyQEPdVVNFDFkNMADGQLHHIMINREEGVVFIEIDDNrRRqVhLSS 1145 ssdtlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCirnvr ++ + +l lG + e+s++ + a +gF+GC++ v+ KIAA1763 1146 GT---EFSAVKSLVLGRILEHSDVDQETALAG------AqGFTGCLSAVQ 1186 inge<-* + ++ KIAA1763 1187 LSHV 1190 PF02210.14.ls: domain 4 of 4, from 1060 to 1190: score 81.4, E = 2.6e-21 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLv.dGrlvlryd FRT t+ lLl++++ + +l++ + ++G l++ry+ KIAA1763 1060 FRT-TRTPSLLLFVSSFyK---------E-YLSVIIAkNGSLQIRYK 1095 lG..sgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g.spg l++ +++v+ ++ ++++DGq H++ + r+++ v +++D+ + ++++++ KIAA1763 1096 LNkyQEPdVVNFDFkNMADGQLHHIMINREEGVVFIEIDDNrRRqVhLSS 1145 ssdtlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCirnvr ++ + +l lG + e+s++ + a +gF+GC++ v+ KIAA1763 1146 GT---EFSAVKSLVLGRILEHSDVDQETALAG------AqGFTGCLSAVQ 1186 inge<-* + ++ KIAA1763 1187 LSHV 1190 //