hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-11023564/chunk_1/iprscan-20080502-11023564.nocrc
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Query sequence: KIAA1727
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF02181.13.ls Formin Homology 2 Domain                       461.6   8.9e-136   1
PF02181.13.fs Formin Homology 2 Domain                       459.7   3.5e-135   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF02181.13.fs   1/1      75   444 ..     1   413 []   459.7 3.5e-135
PF02181.13.ls   1/1      75   444 ..     1   413 []   461.6 8.9e-136

Alignments of top-scoring domains:
PF02181.13.fs: domain 1 of 1, from 75 to 444: score 459.7, E = 3.5e-135
                   *->kkepkpkkkLKpLhWdKlnpsqdrgt.svWdkldeesfekkldldls
                       ++  +kk++++++W+ ++++q+rg++++W+   ++ +++  ++d++
    KIAA1727    75    YSHLGKKKRMRSFFWKTIPEEQVRGKtNIWTLAARQEHHY--QIDTK 119  

                   elEelFsakakkkkekks...seksskskkkkkeisvLDpkrsQNiaIlL
                    +EelF+ ++ ++k++ ++++++ +s+ + +++ei++LD+krs+Ni+I+L
    KIAA1727   120 TIEELFGQQEDTTKSSLPrrgRTLNSSFREAREEITILDAKRSMNIGIFL 169  

                   rklsklppeeivqailemDedvLgvvlflkemldllenLlkmaPtkeElk
                   +++ k++p+ iv+ i+++ +++ g         ++l   lk++P++eE+k
    KIAA1727   170 KQF-KKSPRSIVEDIHQGKSEHYG--------SETLREFLKFLPESEEVK 210  

                   klqekeykgdekspskLgraEqqFLlelskliprleeRlrallFkstFee
                   kl  k+++gd   +skL+ a+ +FL+ l++ +p++++R++a+  k++F +
    KIAA1727   211 KL--KAFSGD---VSKLSLAD-SFLYGLIQ-VPNYSLRIEAMVLKKEFLP 253  

                   eveelkpsletleaAseeLreSrkfkklLeliLalGNyMNsGtrrrGnAk
                   ++  l  ++++l++A++eL++++ ++++L+l+L++GN+MN+G +  GnA+
    KIAA1727   254 SCSSLYTDITVLRTAIKELMSCEELHSILHLVLQAGNIMNAGGYA-GNAV 302  

                   GFkLssLlKLsdvKstidnktTLLHflvkeieesEGkrlEeyrKLklpel
                   GFkLssLlKL+d+K++ +  ++LLHf+++e  +            k   l
    KIAA1727   303 GFKLSSLLKLADTKAN-KPGMNLLHFVAQEAQK------------KDTIL 339  

                   ldfsseLshVekAakvdleeLeadvkeLekglkklekelelseeSkvsde
                   l+fs+ L+hV+k+a+++le+ ea+++ L  + k l+++++  +e      
    KIAA1727   340 LNFSEKLHHVQKTARLSLENTEAELHLLFVRTKSLKENIQRDGE------ 383  

                   epsdkFvevmkeFleeAeekldkLesllkeakelfkelteYFghggedpk
                        ++++m++Fl+ A ekl++Le++ +e++++ + l+++F   +ed+k
    KIAA1727   384 -----LCQQMEDFLQFAIEKLRELECWKQELQDEAYTLIDFF---CEDKK 425  

                   detspeeFFkilrdFlnefk<-*
                    ++ ++e+F+i+rdF+++f+   
    KIAA1727   426 -TMKLDECFQIFRDFCTKFN    444  

PF02181.13.ls: domain 1 of 1, from 75 to 444: score 461.6, E = 8.9e-136
                   *->kkepkpkkkLKpLhWdKlnpsqdrgt.svWdkldeesfekkldldls
                       ++  +kk++++++W+ ++++q+rg++++W+   ++ +++  ++d++
    KIAA1727    75    YSHLGKKKRMRSFFWKTIPEEQVRGKtNIWTLAARQEHHY--QIDTK 119  

                   elEelFsakakkkkekks...seksskskkkkkeisvLDpkrsQNiaIlL
                    +EelF+ ++ ++k++ ++++++ +s+ + +++ei++LD+krs+Ni+I+L
    KIAA1727   120 TIEELFGQQEDTTKSSLPrrgRTLNSSFREAREEITILDAKRSMNIGIFL 169  

                   rklsklppeeivqailemDedvLgvvlflkemldllenLlkmaPtkeElk
                   +++ k++p+ iv+ i+++ +++ g         ++l   lk++P++eE+k
    KIAA1727   170 KQF-KKSPRSIVEDIHQGKSEHYG--------SETLREFLKFLPESEEVK 210  

                   klqekeykgdekspskLgraEqqFLlelskliprleeRlrallFkstFee
                   kl  k+++gd   +skL+ a+ +FL+ l++ +p++++R++a+  k++F +
    KIAA1727   211 KL--KAFSGD---VSKLSLAD-SFLYGLIQ-VPNYSLRIEAMVLKKEFLP 253  

                   eveelkpsletleaAseeLreSrkfkklLeliLalGNyMNsGtrrrGnAk
                   ++  l  ++++l++A++eL++++ ++++L+l+L++GN+MN+G +  GnA+
    KIAA1727   254 SCSSLYTDITVLRTAIKELMSCEELHSILHLVLQAGNIMNAGGYA-GNAV 302  

                   GFkLssLlKLsdvKstidnktTLLHflvkeieesEGkrlEeyrKLklpel
                   GFkLssLlKL+d+K++ +  ++LLHf+++e  +            k   l
    KIAA1727   303 GFKLSSLLKLADTKAN-KPGMNLLHFVAQEAQK------------KDTIL 339  

                   ldfsseLshVekAakvdleeLeadvkeLekglkklekelelseeSkvsde
                   l+fs+ L+hV+k+a+++le+ ea+++ L  + k l+++++  +e      
    KIAA1727   340 LNFSEKLHHVQKTARLSLENTEAELHLLFVRTKSLKENIQRDGE------ 383  

                   epsdkFvevmkeFleeAeekldkLesllkeakelfkelteYFghggedpk
                        ++++m++Fl+ A ekl++Le++ +e++++ + l+++F   +ed+k
    KIAA1727   384 -----LCQQMEDFLQFAIEKLRELECWKQELQDEAYTLIDFF---CEDKK 425  

                   detspeeFFkilrdFlnefk<-*
                    ++ ++e+F+i+rdF+++f+   
    KIAA1727   426 -TMKLDECFQIFRDFCTKFN    444  

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