hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-08165173/chunk_1/iprscan-20080502-08165173.nocrc
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query sequence: KIAA1630
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
PF02779.14.fs Transketolase, pyrimidine binding domain   225.4      6e-66   1
PF02779.14.ls Transketolase, pyrimidine binding domain   227.4    2.9e-65   1
PF00676.10.fs Dehydrogenase E1 component                 122.3    3.5e-34   1
PF00676.10.ls Dehydrogenase E1 component                  87.9    2.8e-23   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
PF00676.10.ls   1/1     205   516 ..     1   327 []    87.9  2.8e-23
PF00676.10.fs   1/1     292   516 ..   104   327 .]   122.3  3.5e-34
PF02779.14.fs   1/1     579   785 ..     1   189 []   225.4    6e-66
PF02779.14.ls   1/1     579   785 ..     1   189 []   227.4  2.9e-65

Alignments of top-scoring domains:
PF00676.10.ls: domain 1 of 1, from 205 to 516: score 87.9, E = 2.8e-23
                   *->yrmmllrRmedarmalykrkgirGFyhlyaGqEAlqvGiaaAldkgv
                      +++  +  ++ ++  ++  +gi+ + +++ ++++l+    ++  +  
    KIAA1630   205    EGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPP- 250  

                   DyviptmPYRdhgvllarGvsk.leevla..elyGreaGcskGkGGSmhm
                   +  +            +rG+s  +e++ a+++  ++ + +++   G  h 
    KIAA1630   251 ELMFRK----------MRGLSEfPENFSAtgDVLSHLTSSVDLDFGAHH- 289  

                   pgyygpknnrfyggngivgaqaqvpipaAvGiAlAakekreQf.....yv
                   p++       ++ ++++++++a +p+++  G ++  +    Q++++++y 
    KIAA1630   290 PLH-------VTMLPNPSHLEAVNPVAV--GKTRGRQ----QSrqdgdYS 326  

                   gd...yrgkkevaitlfGDGAFtnqGqffEalNfAalwklPvgGaIFvce
                   +d++ ++g+ +++   +GD++F +qG++ E+++++ l+   +gG ++ ++
    KIAA1630   327 PDnsaQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIV 376  

                   NNqyAisTpaerssasteyadrArGygIPgirVDGmDplAVyqAvKeAae
                   NNq + +Tpaer+++s + +d ++ +g ++i+V+G+ p++V  A++ A e
    KIAA1630   377 NNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFE 426  

                   rAreGkGPtLIElvTYRygGHsmsDdpstYRtreeveevrkkkDPikrlk
                   + r++ ++++I+l++YR+ GH++ D+p  +  + +++ +r+ k    +++
    KIAA1630   427 YQRQFRKDVIIDLLCYRQWGHNELDEPFYTN-PIMYKIIRARKSIPDTYA 475  

                   khLvskGlvseeElkeiekevrkeieeAvkkAesapepnpe<-*
                   +hL+  Gl ++eE+ ei +++ ++ ++    +  + +p+     
    KIAA1630   476 EHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALN    516  

PF00676.10.fs: domain 1 of 1, from 292 to 516: score 122.3, E = 3.5e-34
                   *->rfyggngivgaqaqvpipaAvGiAlAakekreQf.....yvgd...y
                      +++ ++++++++a +p+++  G ++  +    Q++++++y +d++ +
    KIAA1630   292    HVTMLPNPSHLEAVNPVAV--GKTRGRQ----QSrqdgdYSPDnsaQ 332  

                   rgkkevaitlfGDGAFtnqGqffEalNfAalwklPvgGaIFvceNNqyAi
                   +g+ +++   +GD++F +qG++ E+++++ l+   +gG ++ ++NNq + 
    KIAA1630   333 PGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGY 382  

                   sTpaerssasteyadrArGygIPgirVDGmDplAVyqAvKeAaerAreGk
                   +Tpaer+++s + +d ++ +g ++i+V+G+ p++V  A++ A e+ r++ 
    KIAA1630   383 TTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFR 432  

                   GPtLIElvTYRygGHsmsDdpstYRtreeveevrkkkDPikrlkkhLvsk
                   ++++I+l++YR+ GH++ D+p  +  + +++ +r+ k    ++++hL+  
    KIAA1630   433 KDVIIDLLCYRQWGHNELDEPFYTN-PIMYKIIRARKSIPDTYAEHLIAG 481  

                   GlvseeElkeiekevrkeieeAvkkAesapepnpe<-*
                   Gl ++eE+ ei +++ ++ ++    +  + +p+     
    KIAA1630   482 GLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALN    516  

PF02779.14.fs: domain 1 of 1, from 579 to 785: score 225.4, E = 6e-66
                   *->kkiatrkAsgeALaelaeedprvvgggaDvgaygGtftvtkgllhpq
                       k+++++A+++AL++l++ + +v+++g+Dvg  +Gtf+++++++  q
    KIAA1630   579    IKLDWATAEALALGSLLAQGFNVRLSGQDVG--RGTFSQRHAMVVCQ 623  

                   g.................egRvidtgiaEqamvgianGmAlhGpnllppv
                   +++++  + ++ ++++++  +v +++++E+a++g+++Gm+++ p+llp +
    KIAA1630   624 EtddtyiplnhmdpnqkgFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLW 673  

                   eatFgdFanpAfdQiyadaairryaalgklpvpfvvtrdpiGvGedGPtH
                   ea+FgdF+n  ++Qi++d +i+ ++a++ l+++ +v+++p+G+++ GP H
    KIAA1630   674 EAQFGDFFN--GAQIIFDTFISGGEAKWLLQSG-IVILLPHGYDGAGPDH 720  

                   qsqedeaylraiPg.......e.nNlkVvrPsdpaetkglLraAirsdrd
                   +s++ e++l+++   +++ +++++N+ Vv P++pa++++lLr++    r+
    KIAA1630   721 SSCRIERFLQMCDSaeegvdgDtVNMFVVHPTTPAQYFHLLRRQMV--RN 768  

                   drdPvvlrlprqllrhk<-*
                   +r+P++++ p++llr++   
    KIAA1630   769 FRKPLIVASPKMLLRLP    785  

PF02779.14.ls: domain 1 of 1, from 579 to 785: score 227.4, E = 2.9e-65
                   *->kkiatrkAsgeALaelaeedprvvgggaDvgaygGtftvtkgllhpq
                       k+++++A+++AL++l++ + +v+++g+Dvg  +Gtf+++++++  q
    KIAA1630   579    IKLDWATAEALALGSLLAQGFNVRLSGQDVG--RGTFSQRHAMVVCQ 623  

                   g.................egRvidtgiaEqamvgianGmAlhGpnllppv
                   +++++  + ++ ++++++  +v +++++E+a++g+++Gm+++ p+llp +
    KIAA1630   624 EtddtyiplnhmdpnqkgFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLW 673  

                   eatFgdFanpAfdQiyadaairryaalgklpvpfvvtrdpiGvGedGPtH
                   ea+FgdF+n  ++Qi++d +i+ ++a++ l+++ +v+++p+G+++ GP H
    KIAA1630   674 EAQFGDFFN--GAQIIFDTFISGGEAKWLLQSG-IVILLPHGYDGAGPDH 720  

                   qsqedeaylraiPg.......e.nNlkVvrPsdpaetkglLraAirsdrd
                   +s++ e++l+++   +++ +++++N+ Vv P++pa++++lLr++    r+
    KIAA1630   721 SSCRIERFLQMCDSaeegvdgDtVNMFVVHPTTPAQYFHLLRRQMV--RN 768  

                   drdPvvlrlprqllrhk<-*
                   +r+P++++ p++llr++   
    KIAA1630   769 FRKPLIVASPKMLLRLP    785  

//