# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/ah05473.fasta.huge -Q ../query/KIAA1520.ptfa ./tmplib.25089 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1520, 810 aa
 vs ./tmplib.25089 library

1986695 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 4.6873+/-0.00514; mu= 17.5868+/- 0.351
 mean_var=91.5302+/-21.756, 0's: 0 Z-trim: 4  B-trim: 55 in 2/38
 Lambda= 0.134058

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA1062  ( 1771 res)   hj03579s1                  (1771)  186 47.1   2e-05
KIAA1888  ( 737 res)   fk02242                     ( 737)  179 45.3 2.9e-05


>>KIAA1062  ( 1771 res)   hj03579s1                       (1771 aa)
 initn: 213 init1:  93 opt: 186  Z-score: 189.4  bits: 47.1 E(): 2e-05
Smith-Waterman score: 198;  23.413% identity (60.317% similar) in 252 aa overlap (541-784:319-559)

              520       530       540       550       560       570
KIAA15 SGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVS
                                     : ::   :  ...: .:.   .  .:...:
KIAA10 RTPRLSVMEEDQACAMESRRFEETRGMEEEPTHLPLVVCVDKLTKVYKD-DKKLALNKLS
      290       300       310       320       330        340       

              580       590       600       610       620       630
KIAA15 FSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVS
       ..:  ..:....: .:.::.. ..:: ...:  .: . . :. : . .   ... ...  
KIAA10 LNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRT-EMDEIRKNLGMCP
       350       360       370       380       390        400      

               640         650       660       670       680       
KIAA15 QEPVLFAR-SITDNISYG--LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQL
       :. ::: : .. ... .   : ..  : . .  .:     .: .:.   :..       :
KIAA10 QHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDK-----MIEDLE--LSNKRHSLVQTL
        410       420       430       440              450         

       690       700       710       720       730       740       
KIAA15 SGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLST
       :::.:.....: :.: .  ..:::: :...:  ..  : . :      .:.:. .:... 
KIAA10 SGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDE
     460       470       480       490       500       510         

       750        760       770           780       790       800  
KIAA15 VEH-AHLIVVLDKGRVVQQGTHQQLLAQG----GLYAKLVQRQMLGLQPAADFTAGHNEP
       ..  .  :.....:..   :.   :. .:    :    ::.:                  
KIAA10 ADLLGDRIAIISHGKLKCCGS--PLFLKGTYGDGYRLTLVKRPAEPGGPQEPGLASSPPG
     520       530       540         550       560       570       

            810                                                    
KIAA15 VANGSHKA                                                    
                                                                   
KIAA10 RAPLSSCSELQVSQFIRKHVASCLLVSDTSTELSYILPSEAAKKGAFERLFQHLERSLDA
       580       590       600       610       620       630       

>>KIAA1888  ( 737 res)   fk02242                          (737 aa)
 initn: 207 init1: 102 opt: 179  Z-score: 186.4  bits: 45.3 E(): 2.9e-05
Smith-Waterman score: 179;  22.430% identity (59.346% similar) in 214 aa overlap (569-776:414-620)

      540       550       560       570       580       590        
KIAA15 LAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILE-
                                     .:: .. :.. .:.::.:.:::. .:::  
KIAA18 SIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVG
           390       400       410       420       430       440   

       600       610       620       630        640        650     
KIAA15 NFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQ-EPVLFARSITDNIS-YGLPTVPFEM
       .. :  :   : : .  .. :   : . ..   : .:.    .. ...  ::  .:    
KIAA18 DIEPTSGQVFLGDYSSETSEDDDSL-KCMGYCPQINPLWPDTTLQEHFEIYG--AVKGMS
           450       460        470       480       490         500

         660       670       680       690       700       710     
KIAA15 VVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATS
       . .  .  .     ..:.. .  .: .:   : .: :... .: ... :: . .::: ..
KIAA18 ASDMKEVISRITHALDLKE-HLQKTVKK---LPAGIKRKLCFALSMLGNPQITLLDEPST
              510        520          530       540       550      

         720       730         740       750        760       770  
KIAA15 ALDAESEYLIQQAIHGNLQ--KHTVLIIAHRLSTVEHA-HLIVVLDKGRVVQQGTHQQLL
       ..: ...  . .::.  ..  :..... .: .  .: .   .... .:..   :: :.: 
KIAA18 GMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLK
        560       570       580       590       600       610      

            780       790       800       810                      
KIAA15 AQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA                      
       .. :                                                        
KIAA18 SKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQ
        620       630       640       650       660       670      




810 residues in 1 query   sequences
1986695 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:06:35 2008 done: Thu Dec 18 15:06:36 2008
 Total Scan time:  0.600 Total Display time:  0.040

Function used was FASTA [version 34.26.5 April 26, 2007]