hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-04025332/chunk_1/iprscan-20080502-04025332.nocrc
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Query sequence: KIAA1480
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
PF00135.18.fs Carboxylesterase                             570.8   1.2e-168   1
PF00135.18.ls Carboxylesterase                             460.6   1.8e-135   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
PF00135.18.ls   1/1       1   458 [.     1   592 []   460.6 1.8e-135
PF00135.18.fs   1/1       3   458 ..   131   592 .]   570.8 1.2e-168

Alignments of top-scoring domains:
PF00135.18.ls: domain 1 of 1, from 1 to 458: score 460.6, E = 1.8e-135
                   *->mllllllllllllflavvataptspedpvVeTsyvgGkvrGlrvkvd
                                   ++++ ++                    G     +
    KIAA1480     1    ------------PRVWSPGS--------------------G----AK 11   

                   ggnkpvyaFlGIPYAkPPvGeLRFkkPqPpepWtgvldATkygpaCpQ.n
                                                                  Q+ 
    KIAA1480    12 K----------------------------------------------QgE 15   

                   dlgfpgfslalhvgsemwnkntgksmSEDCLYLNVytPklasenkklPVm
                   dl                  n g   +ED         ++ ++++  PVm
    KIAA1480    16 DLA----------------DNDG---DED---------EDIRDSGAKPVM 37   

                   VwIHGGGFqsGsassvslddydgpdlaasedVVVVtiNYRLGalGFLstg
                   V+IHGG +++G++     ++ dg++la++++V+V+t+NYR+G+lGFLstg
    KIAA1480    38 VYIHGGSYMEGTG-----NMIDGSILASYGNVIVITLNYRVGVLGFLSTG 82   

                   dselppppGNaGLlDQvlALrWVqeNIaaFGGDPdnVTlFGeSAGAaSVs
                   d+ ++   GN+GLlDQ++ALrWV eNIa+FGGDP ++T+FG + GA++Vs
    KIAA1480    83 DQAAK---GNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVS 129  

                   llllSppqsrGLFhrAIlqSGsalspwaitsppearnrakrlAkllGCpg
                   ll+lS  +s+GLF+rAI+qSGsals+wa++++p  ++++  lA ++GC+ 
    KIAA1480   130 LLTLS-HHSEGLFQRAIIQSGSALSSWAVNYQP--VKYTSLLADKVGCNV 176  

                   edseelveCLRkksaeelldaqwklllleefgffplfpFgPVvdGdtpda
                    d  ++v+CLR+ksa+el++++   +++++   f      PV+dGd    
    KIAA1480   177 LDTVDMVDCLRQKSAKELVEQDI--QPARYHVAFG-----PVIDGD---- 215  

                   flpkdPeellkegnfnkvPlliGvtsdEGllflayvl.dp.lsadllsei
                   ++p+dPe+l+++g+f ++++++Gv++ EGl f+  v + ++ +    s  
    KIAA1480   216 VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVdPEdGV----SGT 261  

                   dnedlflellpellpgase.steklreeiadaikeeYtdd.ddnseesrr
                   d+++   +++ ++l+g++e++     + ++++ik++Ytd+ d++++e+rr
    KIAA1480   262 DFDY-SVSNFVDNLYGYPEgK-----DTLRETIKFMYTDWaDRDNPETRR 305  

                   dalldllsDylFvcPilrlalaraakagspvYlYrFdyrssdsfnqyrin
                   + l+ l++D+++v P +++ ++ +a++gsp+Y+Y F +++          
    KIAA1480   306 KTLVALFTDHQWVEP-SVVTADLHARYGSPTYFYAFYHHCQ--------S 346  

                   llwppwrgvsHgdelsYvFGnpls.k.ly....sseeeemlssrrmmryw
                   l++p w  + Hgde++YvFG+p++++++  + ++s+ ++mls +++m+yw
    KIAA1480   347 LMKPAWSDAAHGDEVPYVFGVPMVgPtDLfpcnFSKNDVMLS-AVVMTYW 395  

                   tnFAktGnPN.............ngessglvkWppytkeeqkyylpitll
                   tnFAktG+PN++ +++++  +++ +  +++v W +y++ +q  yl+i+l+
    KIAA1480   396 TNFAKTGDPNkpvpqdtkfihtkANR-FEEVAWSKYNPRDQ-LYLHIGLK 443  

                   nitqk.lreedPrkvkcafw<-*
                   +++++++r+++     +afw   
    KIAA1480   444 PRVRDhYRATK-----VAFW    458  

PF00135.18.fs: domain 1 of 1, from 3 to 458: score 570.8, E = 1.2e-168
                   *->VytPklasenk...................klPVmVwIHGGGFqsGs
                      V++P    ++++++  +++++++++ ++++  PVmV+IHGG +++G+
    KIAA1480     3    VWSPGSGAKKQgedladndgdededirdsgAKPVMVYIHGGSYMEGT 49   

                   assvslddydgpdlaasedVVVVtiNYRLGalGFLstgdselppppGNaG
                   +     ++ dg++la++++V+V+t+NYR+G+lGFLstgd+ ++   GN+G
    KIAA1480    50 G-----NMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAK---GNYG 91   

                   LlDQvlALrWVqeNIaaFGGDPdnVTlFGeSAGAaSVsllllSppqsrGL
                   LlDQ++ALrWV eNIa+FGGDP ++T+FG + GA++Vsll+lS  +s+GL
    KIAA1480    92 LLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLS-HHSEGL 140  

                   FhrAIlqSGsalspwaitsppearnrakrlAkllGCpgedseelveCLRk
                   F+rAI+qSGsals+wa++++p  ++++  lA ++GC+  d  ++v+CLR+
    KIAA1480   141 FQRAIIQSGSALSSWAVNYQP--VKYTSLLADKVGCNVLDTVDMVDCLRQ 188  

                   ksaeelldaqwklllleefgffplfpFgPVvdGdtpdaflpkdPeellke
                   ksa+el++++   +++++   f      PV+dGd    ++p+dPe+l+++
    KIAA1480   189 KSAKELVEQDI--QPARYHVAFG-----PVIDGD----VIPDDPEILMEQ 227  

                   gnfnkvPlliGvtsdEGllflayvl.dp.lsadllseidnedlflellpe
                   g+f ++++++Gv++ EGl f+  v + ++ +    s  d+++   +++ +
    KIAA1480   228 GEFLNYDIMLGVNQGEGLKFVEGVVdPEdGV----SGTDFDY-SVSNFVD 272  

                   llpgase.steklreeiadaikeeYtdd.ddnseesrrdalldllsDylF
                   +l+g++e++     + ++++ik++Ytd+ d++++e+rr+ l+ l++D+++
    KIAA1480   273 NLYGYPEgK-----DTLRETIKFMYTDWaDRDNPETRRKTLVALFTDHQW 317  

                   vcPilrlalaraakagspvYlYrFdyrssdsfnqyrinllwppwrgvsHg
                   v P +++ ++ +a++gsp+Y+Y F +++          l++p w  + Hg
    KIAA1480   318 VEP-SVVTADLHARYGSPTYFYAFYHHCQ--------SLMKPAWSDAAHG 358  

                   delsYvFGnpls.k.ly....sseeeemlssrrmmrywtnFAktGnPN..
                   de++YvFG+p++++++  + ++s+ ++mls +++m+ywtnFAktG+PN++
    KIAA1480   359 DEVPYVFGVPMVgPtDLfpcnFSKNDVMLS-AVVMTYWTNFAKTGDPNkp 407  

                   ...........ngessglvkWppytkeeqkyylpitllnitqk.lreedP
                    +++++  +++ +  +++v W +y++ +q  yl+i+l++++++++r+++ 
    KIAA1480   408 vpqdtkfihtkANR-FEEVAWSKYNPRDQ-LYLHIGLKPRVRDhYRATK- 454  

                   rkvkcafw<-*
                       +afw   
    KIAA1480   455 ----VAFW    458  

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