hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-03575704/chunk_1/iprscan-20080502-03575704.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1477 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00069.15.fs Protein kinase domain 291.7 1.3e-84 2 PF00069.15.ls Protein kinase domain 277.8 2e-80 1 PF02149.10.fs Kinase associated domain 1 89.6 1.3e-24 1 PF07714.7.fs Protein tyrosine kinase 85.0 1.4e-24 3 PF02149.10.ls Kinase associated domain 1 91.6 2.2e-24 1 PF00627.21.fs UBA/TS-N domain 28.1 2.8e-07 1 PF00627.21.ls UBA/TS-N domain 30.1 7.3e-06 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00069.15.ls 1/1 172 401 .. 1 287 [] 277.8 2e-80 PF00069.15.fs 1/2 172 231 .. 1 62 [. 66.7 8.1e-19 PF07714.7.fs 1/3 172 231 .. 1 67 [. 49.2 3.5e-14 PF00069.15.fs 2/2 232 401 .. 85 287 .] 225.0 1.5e-64 PF07714.7.fs 2/3 254 292 .. 120 158 .. 18.9 2.2e-05 PF07714.7.fs 3/3 329 367 .. 198 238 .. 16.9 8.1e-05 PF00627.21.fs 1/1 421 460 .. 1 41 [] 28.1 2.8e-07 PF00627.21.ls 1/1 421 460 .. 1 41 [] 30.1 7.3e-06 PF02149.10.ls 1/1 821 870 .] 1 50 [] 91.6 2.2e-24 PF02149.10.fs 1/1 821 870 .] 1 50 [] 89.6 1.3e-24 Alignments of top-scoring domains: PF00069.15.ls: domain 1 of 1, from 172 to 401: score 277.8, E = 2e-80 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr y+l +++G+G+f++V++a+h+ tg++VAvKii+k ++ ++ ++r KIAA1477 172 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFR 218 lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse E++i+k L+HpNI G + fdyl KIAA1477 219 --EVRIMKILNHPNI----------------------G----EVFDYLV- 239 trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv ++g++ e+ea+ ++Qi+++++Y+H++ i+HRDLK eN+Lld +++ KIAA1477 240 --AHGRM--KEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN 285 vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD + KiaDFG++ + + +l+tf+G+p+Y+APE+ +g +++g++vD KIAA1477 286 I----KIADFGFSNE--FtVGNkLDTFCGSPPYAAPELFQGKKYDGPEVD 329 vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi vWSlGvily l++G +PF+g+ + ++l +++l+++++++++ + KIAA1477 330 VWSLGVILYTLVSGSLPFDGQ-----NLKELRERVLRGKYRIPFYMS--- 371 srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-* ++ L+kk+L ++P kR + e+i+++ w+ KIAA1477 372 ------------TDCENLLKKLLVLNPIKRGSLEQIMKDRWM 401 PF00069.15.fs: domain 1 of 2, from 172 to 231: score 66.7, E = 8.1e-19 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr y+l +++G+G+f++V++a+h+ tg++VAvKii+k ++ ++ ++r KIAA1477 172 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFR 218 lsEiqilkrLsHpNI<-* E++i+k L+HpNI KIAA1477 219 --EVRIMKILNHPNI 231 PF07714.7.fs: domain 1 of 3, from 172 to 231: score 49.2, E = 3.5e-14 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.keigaseeei +l+k++G+G+F +V +++ t+ +VAVK+++k + + KIAA1477 172 YRLQKTIGKGNFAKVKLARHV----LTGREVAVKIIdKT-QLNPTS- 212 eredFlrEAsiMkklGdHpNi<-* +++++rE++iMk l +HpNi KIAA1477 213 -LQKLFREVRIMKIL-NHPNI 231 PF00069.15.fs: domain 2 of 2, from 232 to 401: score 225.0, E = 1.5e-64 *->GLrvldLfdylsetrrkgpllfsedeakkialQilrgleYLHsngii G + fdyl ++g++ e+ea+ ++Qi+++++Y+H++ i+ KIAA1477 232 G----EVFDYLV---AHGRM--KEKEARAKFRQIVSAVQYCHQKYIV 269 HRDLKPeNILldnngvvdaflKiaDFGlAkklst.sss.lttfvGTpwYm HRDLK eN+Lld ++++ KiaDFG++ + + +l+tf+G+p+Y+ KIAA1477 270 HRDLKAENLLLDGDMNI----KIADFGFSNE--FtVGNkLDTFCGSPPYA 313 APEvllggngygtkvDvWSlGvilyelltGkpPFsgevqdsldqlqlirk APE+ +g +++g++vDvWSlGvily l++G +PF+g+ + ++l ++ KIAA1477 314 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ-----NLKELRER 358 ilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRltae +l+++++++++ + ++ L+kk+L ++P kR + e KIAA1477 359 VLRGKYRIPFYMS---------------TDCENLLKKLLVLNPIKRGSLE 393 eilqHPwf<-* +i+++ w+ KIAA1477 394 QIMKDRWM 401 PF07714.7.fs: domain 2 of 3, from 254 to 292: score 18.9, E = 2.2e-05 *->lQiAkGMeYLesknfvHRDLAARNcLVsenlvVKIsDFG<-* +Qi ++ +Y ++k +vHRDL A N L++ ++ +KI+DFG KIAA1477 254 RQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFG 292 PF07714.7.fs: domain 3 of 3, from 329 to 367: score 16.9, E = 8.1e-05 *->DVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLp<-* DVWS GV L+ +++ G P + g e+ e++ + yR p KIAA1477 329 DVWSLGVILYTLVS-GSLP-FDGQNLKELRERVLRGKYRIP 367 PF00627.21.fs: domain 1 of 1, from 421 to 460: score 28.1, E = 2.8e-07 *->ideeavkqLreMTGfdreeakkALeatngnverAvewLleh<-* d + + ++ M Gf r+e+ +AL + ++++ +A+++Ll + KIAA1477 421 NDTKRIDIMVTM-GFARDEINDALINQKYDEVMATYILLGR 460 PF00627.21.ls: domain 1 of 1, from 421 to 460: score 30.1, E = 7.3e-06 *->ideeavkqLreMTGfdreeakkALeatngnverAvewLleh<-* d + + ++ M Gf r+e+ +AL + ++++ +A+++Ll + KIAA1477 421 NDTKRIDIMVTM-GFARDEINDALINQKYDEVMATYILLGR 460 PF02149.10.ls: domain 1 of 1, from 821 to 870: score 91.6, E = 2.2e-24 *->ddksksvvkFEiqlyKlprldlyGvdfqRisGpqwlFkdLcsailne d++++s+v++E++++Klprl+l+Gv+f+RisG++++Fk+++s+i+ne KIAA1477 821 DARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANE 867 Lkv<-* L + KIAA1477 868 LML 870 PF02149.10.fs: domain 1 of 1, from 821 to 870: score 89.6, E = 1.3e-24 *->ddksksvvkFEiqlyKlprldlyGvdfqRisGpqwlFkdLcsailne d++++s+v++E++++Klprl+l+Gv+f+RisG++++Fk+++s+i+ne KIAA1477 821 DARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANE 867 Lkv<-* L + KIAA1477 868 LML 870 //