hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/smart.HMMs.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-03274986/chunk_1/iprscan-20080502-03274986.nocrc
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Query sequence: KIAA1459
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SM00219                                                 433.0   1.6e-125   1
SM00220                                                 158.3      8e-43   1
SM00060                                                  93.7    2.2e-23   2
SM00454                                                  74.4    1.4e-17   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
SM00060    1/2     177   267 ..     1    69 []    36.5  3.6e-06
SM00060    2/2     288   369 ..     1    69 []    57.1  2.2e-12
SM00219    1/1     483   740 ..     1   280 []   433.0 1.6e-125
SM00220    1/1     483   744 ..     1   231 []   158.3    8e-43
SM00454    1/1     775   842 ..     1    67 []    74.4  1.4e-17

Alignments of top-scoring domains:
SM00060: domain 1 of 2, from 177 to 267: score 36.5, E = 3.6e-06
                   *->PgpPsnptelrvtdvtststsdltsvtlsWepP.......ivgYr..
                      P++P n   l  + v+ t      svtl+W pP ++++ + ++Y  +
    KIAA1459   177    PSAPVN---LISS-VNGT------SVTLEWAPPldpggrsDITYNav 213  

                   ...............................ytltgLkPgaepwteYefr
                    ++ ++  ++ +  +++++ ++++++ ++ +  + +L ++     +Y+f+
    KIAA1459   214 crrcpwalsrceacgsgtrfvpqqtslvqasLLVANLLAH----MNYSFW 259  

                   VrAvngndaGeg<-*
                   + Av    +G +   
    KIAA1459   260 IEAV----NGVS    267  

SM00060: domain 2 of 2, from 288 to 369: score 57.1, E = 2.2e-12
                   *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr...
                      P+ +     +r +  + t      sv+l W++P+ +++ i++Y+ + 
    KIAA1459   288    PSQVVV---IRQERAGQT------SVSLLWQEPeqpngiILEYEiky 325  

                   ...................ytltgLkPgaepwteYefrVrAvngndaGeg
                    +++++ ++ ++ + +++++t++gLkPg    t+Y+f+VrA+++  aG g
    KIAA1459   326 yekdkemqsystlkavttrATVSGLKPG----TRYVFQVRARTS--AGCG 369  

                   <-*
                      
    KIAA1459     -     -    

SM00219: domain 1 of 1, from 483 to 740: score 433.0, E = 1.6e-125
                   *->ltlgkkLGeGaFGeVykGtlk......ieVAVKtLkeda....keeF
                      ++ +k++G+G  GeV+ G+l+ +++++++VA+K Lk++ +++++++F
    KIAA1459   483    IHIEKIIGSGDSGEVCYGRLRvpgqrdVPVAIKALKAGYterqRRDF 529  

                   lrEakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLl
                   l+Ea+iM ++  +HpNi++L Gv+t +          miv+Eyme+G+L+
    KIAA1459   530 LSEASIMGQF--DHPNIIRLEGVVTRG-------RLAMIVTEYMENGSLD 570  

                   dyLrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenk
                    +Lr + ++++  +L+ +   + +GM+YL++ ++vHRDLAARN+Lv++n+
    KIAA1459   571 TFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNL 620  

                   vvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkd
                   v+K+sDFGLsR l+dd        y ++    ggk  +PirW+APE++ +
    KIAA1459   621 VCKVSDFGLSRVLEDD----PDAAYTTT----GGK--IPIRWTAPEAIAF 660  

                   gkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyRl
                   ++F+s+SDVWSFGV++WE++ +Ge PY++     m+n++v+  +++GyRl
    KIAA1459   661 RTFSSASDVWSFGVVMWEVLAYGERPYWN-----MTNRDVISSVEEGYRL 705  

                   pkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFselverl<-*
                   p P          CP +l++lMl+CW+ d ++RP+Fs++v+ l   
    KIAA1459   706 PAPMG--------CPHALHQLMLDCWHKDRAQRPRFSQIVSVL    740  

SM00220: domain 1 of 1, from 483 to 744: score 158.3, E = 8e-43
                   *->YellkklGkGaFGkVylardkk...tgrlvAiKvik........eri
                       ++ k++G+G  G+V+ +r + +++ +  vAiK +k + ++++++++
    KIAA1459   483    IHIEKIIGSGDSGEVCYGRLRVpgqRDVPVAIKALKagyterqrRDF 529  

                   lrEikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrg
                   l+E +i+ + dHPNI++L +v   +    +V+Ey+e+  G+L ++l+ + 
    KIAA1459   530 LSEASIMGQfDHPNIIRLEGVVTRgRLAMIVTEYMEN--GSLDTFLRTHD 577  

                   rrglrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hv
                   ++     ++  +   ++r +  ++ YL ++g +HRDL   N+L+ds+ + 
    KIAA1459   578 GQ-----FTImQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSnlVC 622  

                   KlaDFGlArql..........ttfvGTpeYmAPEvl...gYgkpavDiWS
                   K++DFGl+r+l+++++   ++t       + APE +  + ++  a+D+WS
    KIAA1459   623 KVSDFGLSRVLeddpdaayttTGGKIPIRWTAPEAIafrTFSS-ASDVWS 671  

                   lGcilyEllt.GkpPFp...qldlifkkig..........SpeakdLikk
                   +G++++E l+ G+ P+++ ++ d+i  +  +++ + + + ++ + +L+  
    KIAA1459   672 FGVVMWEVLAyGERPYWnmtNRDVISSVEEgyrlpapmgcPHALHQLMLD 721  

                   lLvkdPekRlta.eaLedeldikaHPff<-*
                   +++kd ++R+  +++        ++  +   
    KIAA1459   722 CWHKDRAQRPRFsQIVS-----VLDALI    744  

SM00454: domain 1 of 1, from 775 to 842: score 74.4, E = 1.4e-17
                   *->vs.wspesVaeWLesigleqYadnFrkngidgeelllltseedLkel
                        +    +V++WL+si++++Y+d+F++ g+++  ++l+++ +d   l
    KIAA1459   775    SGgGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRAL 821  

                   GitllGhRkkIlsaiqklkeq<-*
                   Gitl Gh+kkIl +iq++++q   
    KIAA1459   822 GITLMGHQKKILGSIQTMRAQ    842  

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